ANK₃ 유전자 다형성과 조현병의 연관성에 대한 연합연구

양소영,허익수,조은영,최미지,박태성,이유상,홍경수,Yang, So Yung,Huh, Ik-Soo,Cho, Eun Young,Choi, Mi Ji,Park, Taesung,Lee, Yu-Sang,Hong, Kyung Sue 대한생물정신의학회 2015 생물정신의학 Vol.22 No.4

Objectives Previous genome-wide association studies have indicated the association between ankyrin 3 (ANK3) and the vulnerability of schizophrenia. We investigated the association between single nucleotide polymorphisms (SNPs) covering the whole ANK3 locus and schizophrenia in the Korean population. Methods The study subjects were 582 patients with schizophrenia and 502 healthy controls. Thirty-eight tag SNPs on ANK3 and five additional SNPs showing significant association with schizophrenia in previous studies were genotyped. Results Three (rs10994181, rs16914791, rs1938526) of 43 SNPs showed a nominally significant association (p < 0.05) with at least one genotype model. But none of these associations remained significant after adjusting for multiple testing errors with Bonferroni's correction. Conclusions We could not identify a significant association between ANK3 and schizophrenia in the Korean population. However, three SNPs showing an association signal with nominal significance need to be investigated in future studies with higher statistical power and more specific phenotype crossing the current diagnostic categories.

정한모 초기시 연구 : ‘되기’의 상상력과 연대 의식을 중심으로

양소영(Yang So Young) 한국언어문학회 2020 한국언어문학 Vol.114 No.-

The purpose of this paper is to examine the realization of existence and the aspect of life that appeared in Jeonghanmo s early days. First of all, darkness appears in his early days, when darkness allows the poet to experience the innermost experience, which means hope and vitality beyond the passage of time. This situation allowed the poet to confront a war of masculine and destructive power. Therefore, darkness served as an image that strengthened the poet s vitality. Many stones come out in the early days. In particular, his stone acts as a driving force that embodies the manifestation of existence. The poet is lonely and anxious due to the experience of war, but he spurs on the realization of existence to overcome this situation. Therefore, ordinary stones are themselves but such stones make them escape the boundaries of human beings. Gradually becoming a stone becomes transcendental beyond the realization of one s own existence. In the early days erosive imagination emerges when eros act as a solidarity rather than as a simple principle of pleasure. Human beings themselves are in a state of discontinuity, and beyond this sense of isolation or anxiety, the sense of continuity is figuratively present as sexual pleasure. In his poem, Eros goes beyond the question of sex and has continuity and emphasizes solidarity.

초등학교 4학년의 음악적성과 청각인지능력 상관관게 연구

양소영 ( So Young Yang ) 민족음악학회 2008 음악과 민족 Vol.36 No.-

정한모 시에 나타난 시간의 의미 연구

양소영(Yang so young) 한국언어문학회 2015 한국언어문학 Vol.94 No.-

This research aimed at examining the meaning of time in Jeong, hanmo's poem. The existing researches on Jeong, hanmo's poem have understood the overall world of his poem as 'humanism' or concentrated on the baby in his poem or the analysis of the image related to the baby. This is the case which merely investigating Jeong, hanmo's poem world by limiting it. In his poem, various aspects of life were expressed with various images besides the image of a baby. However, meanwhile the researchers have not proceeded systematic and thoughtful discussion on this. In Jeong, hanmo's poem, the expressions of time appear frequently. In his poem, there are lots of expressions of time, e.g. "in the depth of the night where the darkness is piling up, in the arm of the night where the darkness is piling up"(｢In the depth of the night where the darkness is piling up｣), "Inside of the night which we lived today, which used be the darkness of you and me”(｢Binghwa｣), “In the dark night far from the starlight”(｢With the wind｣), in his early poem, “In the dawn when your voice wet in each layer”(｢Waterway of the night｣), “The dawn is a white wall today also”(｢Gladiolus｣) “Subdued silence becomes a warm temperature on this awakened dawn”(｢Song of a stone｣) in his medium-dated poem, “The snow piled up during the night covers the river of time. That side over the bridge of 60 years”(｢four or five-year old child｣), “In the time spent over the 60 years of the river of history flown windingly”(｢Fields of hometown｣) “In the middle of the open sea covered with the darkness over the 50 years”(｢My solitude is｣) in his late-dated poem, etc. This way, Jeong, hanmo's poem treated the part related to time importantly, there's no research on time until now, since the meanwhile researches have focused on the baby or the image analysis related to the baby. Time in Jeong, hanmo's poem can be considered by being connected with the process of self-recognition of the main agent, related to the clarification of self. This is meeting the inside of true self, which is the introspection within the existence. The night in Jeong, hanmo's early poem shows the state of solitude, however the poet makes the reader look back on the self through the night. The night functions for the poet as the medium between the main agent and the self-awareness. For him, the night makes more inner sense. In this inner secrecy, the poet introspect the existence. Here, furthermore, the time, 'the dawn', opened deeper sense of the poet in his medium-dated poems, Baby's roomand The dawn. As the result, this sense made the pot grow insight into the world and made open thought. Through the expression of “The dawn is open eye tomorrow also”(｢Gladiolus｣), the dawn makes open thought to cope with the pain of life by dissolving the poet's own lethargy. This enables one to overcome the negative reality and recover the positive self. In the medium-dated poem, the poet gets the open thought thanks to 'the dawn', and in his late-dated poem, this open thought is sublimated to reach the transcendent territory which has no division between the self and the world. This point appears in his poem as the reminiscence of hometown. In his late-dated poem, Baby's room messenger and Standing at the starting point, the poet reminisces the past centered with the present through the expressions of “Now I return to the starting point. At the starting point to return after sixty years” (｢Seojang｣), “Hometown 50 years ago”(｢Jeomgyeong｣). This is to remember the pure time, the poet wants to maintain the identity of self by replaying the past in the present. This is to transcend the boundary of all territories, where the negative real world is overcome, and to establish a positive and volitional identity, rather

정한모 시에 나타난 자기애 양상 연구

양소영(Yang So-young) 한국비평문학회 2009 批評文學 Vol.- No.32

Sinking to inner world and alienation and sense of loneliness, which are prominent in Jeong Hanmo’s early poems, remind us of ‘narcissism’ in the psychology. Freud defines narcissism as libidinal. That the subject in symbolic world withdraws interest and love from object to itself is not different from an attempt to recur to the complete union of subject and object which was enjoyed in one’s infancy. At this point, the subject forms a connection with the object in the fantasy that is reorganized to meet one’s ego impulse , instead of the external object in the real world. Therefore, the object that the narcissistic subject experiences is, after all, the other as reflection of the ego, i.e. an altered ego, and a narcissistic transition is accompanied. And it appears as emotional manifestation like the process of represented by image, recognition of self-existence situation through alienation and sense of loneliness, and longing for primitive maternal world. In his middle and latter years poems, it can be said that serous attempts were made to meet Jeong Hanmo’s narcissistic desire. Image of baby and image of sea are structures that can make feel enough narcissistic satisfaction. And Jeong Hanmo identify tree, who has the same situational identity as him, with him and discovers his from them. That is, he experiences narcissism that feels his own ideal self-image through such self ideals. However, the subject cannot help but inevitably encounter evidences of lack of self in such a narcissistic transition. Therefore, the poems of playing with words that exhibit evidence of lack and nihility residing in the other side of narcissism. We can see that, like this, the process to rather tame nihility in semiotic world is also to exhibit the narcissistic desire of the subject that pursues the world of primitive satisfaction.

고든의 음악학습이론에 나타난 심리학적 접근 요소

양소영 ( So Young Yang ) 민족음악학회 2007 음악과 민족 Vol.34 No.-

김여정 시에 나타난 에코페미니즘 특성 연구

양소영 ( Yang So Young ) 한성대학교 한성어문학회 2021 漢城語文學 Vol.45 No.-

이 글의 목적은 김여정 시에 나타난 여러 자연 이미지, 생명의 특성, 어머니를 복합적으로 분석하여 그녀의 시 세계를 풍요롭게 이해하는 데 있다. 초기시에 나타난 레몬의 생명력은 자연과 인간의 공감을 이끌어 낸다. 이때 공감이라는 것은 자연과 인간의 상호 작용을 의미한다. 자연과 인간의 공감은 긍정적인 자아 형성을 이룰 수 있게 한다. 초기시에서 시인은 레몬을 통해 자연과 인간의 상호 관계를 확인하는데 이는 소중한 여성적 가치를 얻게 하며 긍정적인 자아 형성을 하게 한다. 이것은 가부장제 속의 고립된 자아에서 벗어날 수 있는 동력으로 작용한다. 중기시의 비상의 이미지는 자연과 인간의 조화를 이끈다. 시인은 자연과 인간의 조화와 합일 속에 ‘관계적 자아’를 형성하며 그 결과, 그녀는 자신을 둘러싼 여러 문제를 능동적으로 해결할 수 있는 확장된 자아, 즉, 능동적 자아를 얻게 된다. 관계적 자아는 가부정적 질서에 대응해 여성의 위치를 평등하게 바라보고자 하는 의미를 지닌다. 게다가 시인은 새의 비상을 통해 자연과 인간 전체에 생명을 나누며 순환의 질서와 관계성의 원리를 경험하게 된다. 후기시에 나타난 어머니는 평범함 속에서도 극락조, 정자나무와 연결되며 여신의 면모를 지닌다. 즉, 어머니는 영적인 대상으로 가족과 모든 것을 포용할 수 있는 내밀한 가치를 지닌 영원한 존재이다. 어머니의 영적인 힘은 자아와 세계 등 이원적인 경계를 허물어 버린다. 어머니는 모든 것을 사랑할 수 있는 힘을 지녔고, 이런 사랑은 자연과 여성을 속박하는 가부장적 상황을 해체시킨다. 이런 점은 주체적인 특성을 보여준다. The purpose of this article is to comprehensively analyze the natural images, the characteristics of life, and the mother to understand in Kim Yeo-jung’s poems and to reach a rich understanding of the world of her poetry. The vitality of lemons in early poems derives between nature and humans. In this case, empathy means the interaction between nature and humans. Empathy between nature and humans allows for positive self-formation. In early poetry, the poet confirms the relationship between nature and humans through lemons, which acts as a driving force to make the poet realize a person of positive and precious value and escape from the isolated self in an uneasy reality. The imagination of soaring in the mid-term period poetry leads to harmony between nature and humans. The poet forms a “relational self” in harmony with nature and humans, resulting in an extended self, that is, an active self, that can proactively solve the problems surrounding herself. In addition, the poet experiences the circular order and the principle of relationship, sharing life with nature and humans through a bird’s soaring The mother, who appeared in the late poetry, appears as a goddess by being connected to the a bird of paradise and shade tree. In other words, the mother is an eternal being who has an innate value to embrace her family and everything as a spiritual object. The spiritual power of a mother breaks down dualistic boundaries such as self and the world. The mother has the power to embrace everything, and this ability dissolves nature and the patriarchal situation that binds women. This shows proactive and subjective characteristics.

윤동주 동시에 나타난 상승 이미지 연구

양소영 ( So Young Yang ) 경희대학교 인문학연구원 2014 인문학연구 Vol.0 No.26

원은 원 이미지를 형성한다. 가족 공동체 구성원은 서로 응집시키며 내밀함을 나타낸다. 이런 내밀성은 가족들에게 친밀감을 만들어준다. 가족 공동체 구성원에 나타난 내밀함은 세계와 친밀하게 만들어 그들과 하나가 되는 순수한 마음이 담겨 있다. 이런 내밀함으로 윤동주는 당시 식민지 현실의 외로움, 슬픔을 밝고 화해로운 세계로 이끈다. 원 이미지에 나타난 순수한 마음은 확장되어 별, 눈, 새벽 이미지로 인해 열린 사유를 만들어 놓는다. 이런 열린 사유를 통해 시인은 자아와 세계의 이분법적 세계관을 허물어 버리며, 모든 사물과 하나가 된다. 열린 사유는 당시 식민지 현실에 지치고 힘든 시인에게 구원의 사유가 된다. 특히, 새벽 이미지에 주목할 필요가 있다.『아기의 새벽』에서 새벽은 존재의 솟구침과 연결시켜 생각할 수 있고, ‘아기가 젖달라 울어서 새벽이 된다’란 표현을 볼 때 아기의 울음도 존재의 성찰과 연관된다. 새벽과 아이의 울음은 시인에게 자신의 내면을 치유하게 하며, 그는 긍정적인 자아를 찾는다. 윤동주는 긍정적인 내면 속에서 세계를 좀 더 순수하게 바라볼 수 있게 된다. 이때의 마음은 자아와 세계에 대한 경계가 없고 모든 사물과 하나가 되는 열린 세계이다. 이는 상승의 영역이기도 하다. 그러므로 상승 이미지는 시인의 역동적인 삶을 의미하기도 하다. 이 역동적인 삶은 모든 사물과 하나가 되는 열린 정신을 의미하고, 이런 정신 속에서 시인의 시 세계가 더욱 확장되게 된다. The bright, light, and happy world is frequently shown in rise’s image when you read children’s poems by Yun Dong-joo. This image of rise is shown as the wind, sunlight, circles, stars, snow, and dawn in his children’s poems. There are a lot of daily and ordinary poetic diction in them. But, they rather make you interpret his children’s poems in various ways. Various aspects of life are shown in his children’s poems and painful absence of the present was also expressed. However, pain from absence of the present is removed through freedom of the wind’s image shown in children’s poems by Yun Dong-joo. ‘Sunlight’ and ‘the wind’ shown in 「Sunlight、the Wind、」 and ‘Let’s go’ done in 「Glow of fireflies」 create the wind’s image. In addition, freedom shown in the wind’s image forms the backbone of communication with other things and gets to seek the more fundamental desire. As rise’s image shown in children’s poems by Yun Dong-joo is expressed as various aspects of transformation, it makes the poet’s poetic world richer. For example, it’s circles’ image. The circles cohere themselves and establish the existence inside privately. The circles cohere and expand. They are connected to the force of rising air. The poet gets to seek his earnest wish through these circles. For example, the members of the family community that my father, my mother, my elder sister, and myself sit together with the red apples in 「apples」 form circles’ image. The members of the family community cohere each other show privacy. This privacy makes the family feel a sense of closeness with each other. The privacy shown in the members of the family community is also imagination of innocence to be one by making them be intimate with the world. the members get to confirmed their love about their family beyond absence of the present and the narrator satisfies his desire through this privacy. Rise’s image in children’s poems by Yun Dong-joo is shown as stars, snow, and dawn. Especially, you need to take note of dawn. Dawn in 「A baby’s dawn」 can be thought by connecting it to ebulliency of the existence. The baby’s crying is connected to introspection of the existence when you read the expression, ‘Daylight has come because the baby cries asking for milk.’ The dawn and the baby’s crying have the same implicit meaning of inscape. They give the poet strength to heal his inner side. And as the result, he finds positive ego. Yun Dong-joo gets to look at the world more genuinely in his positive inner side. At this moment, his mind is connected to his ego and the world and the world is opened by becoming one with all the things. This is also the rising area. Rise means the poet’s dynamic life. This dynamic life means an open mind that he becomes one with all the things. And the width of poetic tension gets wider and the poet gets to recognize the hidden side of life.

올바른 약물 이용 지원 시범사업 성과 연구

양소영 ( Yang So-young ),장선미 ( Jang Sunmee ),권순홍 ( Kwon Sun-hong ),이주연 ( Lee Juyeun ),아영미 ( Ah Youngmi ),강신우 ( Kang Cinoo ),홍성현 ( Hong Sung-hyun ),박혜경 ( Park Hyekyung ) 한국보건사회연구원 2020 保健社會硏究 Vol.40 No.3

본 연구의 목적은 약사가 환자의 거주지를 방문하여 약물 사용의 적절성과 부작용 발생 여부를 파악하고 약물에 대한 정보제공 및 복약지도를 실시하는 ‘올바른 약물 이용지원’ 시범사업의 효과를 평가하는 것이다. 시범사업에서는 다제약물을 복용하는 만성 질환자를 건강보험청구자료를 이용해 선정하여, 사업 참여에 동의한 사람에 대해 총 4차례의 상담교육을 진행하였다. 대상자의 복약순응, 약물 관련 인지, 중복투약 등을 현황을 파악하고, 1차와 4차에서 조사한 현황을 비교하였다. 4차에 걸친 상담 결과, 약물 인지도, 복약순응도, 일반적인 약물 지식 수준이 개선되었으며, 전체적으로 중복투 약 환자 분율이 감소하였다. 의약사 지시에 따른 불용의약품 발생률이 증가하였으며, 자의적 판단으로 불용의약품을 발생시키는 비율이 줄어들었다. 본 시범사업은 환자의 약물 사용을 포괄적으로 관리할 수 있는 새로운 프로그램을 개발했다는 점에서 의의가 있다. 그러나 보건의료 직능 간 협업체계가 제대로 구축되지 않아 약사에 의해 파악된 약물관련문제가 충분히 개선되지 못한 부분이 존재하며, 이는 향후 사업 추진에서 개선 되어야 할 과제이다. 이를 위해 현재 운동과 영양 관리를 수행하고 있는 지역사회일차의 료지원센터에 본사업을 결합시키는 방안도 고려해볼 수 있겠다. The purpose of our study was to evaluate the effectiveness of the pilot project for polypharmacy management, in which pharmacists visit participants’ residences to identify the appropriateness of medication use and the incidence of adverse events, provide medication reconciliation, and educate how to manage medication. In the pilot program, health insurance claims data were used to identify the polypharmacy patients with chronic diseases, and a total of four counseling sessions were conducted for patients who agreed to participate in the program. The status of the patients’ medication adherence, medication-related awareness, and medication duplication was identified, and the results from the first and fourth rounds of consultation were compared. The medication-related awareness, medication adherence, and general knowledge of medication were improved. The incidence rate of unused medication according to the decision of healthcare provides increased, while that of unused medication due to patients’ own decisions decreased. This pilot project is a new comprehensive program for medication management. However, the medicationrelated problems identified by pharmacists have not been sufficiently reconciled due to the lack of a cooperative system among healthcare providers, which is a task to be improved in the future. Combining this program with Community-based Primary Medical Support Center, which currently conducts exercise and nutrition management, can be also considered.

오장환 시에 나타난 환상성 연구

양소영 ( Yang So Young ) 단국대학교 한국문화기술연구소 2022 한국문화기술 Vol.32 No.-

이 논문의 목적은 오장환 시에 나타난 비현실적인 요소 즉 환상적인 특성을 중심으로 로즈메리 잭슨의 환상성 이론에 의해 그의 시를 새롭게 분석하는데 있다. 우선, 2장에서 시인은 근대화된 도시에 나타난 편리함을 절망의 시선으로 바라보며 도시를 노동자의 죽음 등 부정적인 이미지로 형상화했다. 특히, 시인은 근대화가 만들어낸 병폐에 민감하게 반응하고 이런 병폐를 희극과 비극을 교차하면서 즉 환상적으로 표현하였다. 3장에서 시인은 황혼 속에서 실재와 비실재의 경계를 확인하고 자신의 내면을 바라보게 된다. 「병실」과 「체온표」에 나타난 고열 속의 시적 화자의 환상은 순수하게 이상적 자아를 찾고자 하는 의지가 담겨 있는 부분이다. 4장에서 시인은 자신의 내면의 결핍을 어머니의 모성적 환타지를 통해 치유하고자 했다. 그에게 환상은 불안한 자아를 회복하는, 내적 자아의 극복 양상 과정을 담고 있다. 이는 고통받는 시인의 모습에서 벗어나 진실을 찾아나서는 시인의 모습을 보여주는 부분이기도 하다. 시 속에 나타난 어머니는 현실 세계에 존재하는 절대적 여신으로 이런 점은 부조화로 이루어진 근대 도시를 잊어버리게 한다. 특히 시에 나타난 어머니는 자식의 모든 것을 걱정하고 포용하는 존재로, 이는 모성적 환상을 보여준다. 그에게 영원할 것 같은 고통스런 여정이 모성적 환상에 의해 긍정적으로 바뀌며 결국 시인은 불안한 자아를 극복하며 능동적인 자아를 발견하게 된다. The purpose of this paper is to analyze his poems in abundance by Rosie Jackson’s Theory of Fantasticity, focusing on the unrealistic side-fantastic elements that appeared in O Jang-hwan’s poem. The illusions in his poetry caused his inner lack, and he extended this inner confusion to unrealistic aspects. Even if the poet’s fantasy shows a dominant resistance to reality, it is not a escapist tendency, but rather he seeks symbiotic relationships through fantasy and heals the inner side of living in pain. In Chapter 2, the poet expressed the desperate situation of a modern city through the image of death, expressing a city without vitality. His poem expressed the mechanized city of the 1930s as an image of the death of a worker, showing the ills of society. The poet despair at the incongruity created by modern times, reacting sensitively to the reality at the time and having an ego of vigilance. Eventually, he expressed his surroundings in a fantastic way to get out of the city. In Chapter 3, the poet lived in a city and was lonely, but through fantasies on the border between reality and unreality, he looked at the inner nature in desperate situations and found a stable self. The poetical self experiences the process of identifying the goldfish and the self, and the fantasy in such high fever contains the poet speaker’s willingness to find the ideal self in purity. In Chapter 4, “Perfume” is a poem that the poet misses his mother in her hometown, showing her continuing to worry about her son in her mother’s fantasy, which shows maternal fantasy as a target of care and love for her child’s safety. In the motherly fantasy, the poetic self reflects on itself rather than comfort and affection. It is the mother who lets us escape the unstable reality. In “I like faith in my child’s whereabouts, whose motherhood is unknown,” motherhood to a poet is the subject of healing the self, which lives in pain with an inner deficiency in eternal time. The illusion shown in O Jang-hwan’s poem is not revealed by existing researchers, and this attempt reveals various reasons for the poetic subject and is also the way to find O Jang-hwan’s own new expression. analyzing O Jang-hwan’s poem from a fantastic perspective is a part of the poet who has been suffering O Jang-hwan and finding the truth of his life. The illusion shown in his poem can be understood as an active dimension, away from the mere escape of reality. The fantasy in O Jang-hwan’s poem played an important role in revealing the situation of the 1930s, and as a result, it proves that he was an important poet in the 1930s.