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가감팔물탕(加減八物湯)을 투여한 아토피 피부염 환자 104명의 경표피수분손실율 변화
안상훈,이종훈,Ahn Sang-Hoon,Lee Jong-Hoon 대한한의학방제학회 2003 大韓韓醫學方劑學會誌 Vol.11 No.1
The skin is a barrier between the living organism and its environment, and this barrier function resides in the stratum corneum. The main function of the stratum corneum is to serve as a barrier preventing the penetration of irritants and transepidermal water loss(TEWL). The rate of transepidermal water loss is a convenient parameter for expressing barrier function. Impaired barrier function was manifested by a greatly increased rate of transepidermal water loss. In atopic dermatitis the rate of transepidermal water lossis greatly increased transepidermal water loss. Medication of Gagampalmultang restored to normal the abnormally high rates of transepidermal water loss in the 104 patients with atopic dermatitis. It specifically plays an important role in regulating barrier function.
안상훈 ( Sang Hoon Ahn ),박승우 ( Seung Woo Park ),정재복 ( Jae Bock Chung ),이진헌 ( Jin Heon Lee ),이세준 ( Se Joon Lee ),정준표 ( Jun Pyo Chung ),송시영 ( Si Young Song ),강진경 ( Jin Kyung Kang ) 대한췌담도학회 1999 대한췌담도학회지 Vol.4 No.1
The Mirzzi syndrome, which occurs in 0.7~1.4% of patients undergoing cholecystectomy, is an unusual benign obstruction of common hepatic duct resulting from ex-trinsic compression by a gallstone impacted in either the neck of the gallbladder or the cystic duct. The aim of this study is to investigate the clinical features of Mirizzi syndrome. From January 1989 to April 1998, among 1,320 patients with gallstone disease, 17 patients were diagnosed as having Mirizzi syndrome at Severance Hospital. Their medical records were reviewed and their clinical, radiological, and surgical features were analysed retrospectively. The incidence of Mirizzi syndrome was 1.3% (17/1320). Included patients comprised of 12 males and 5 females, with an average age of 59.0 years (range 3~86). 2. The presenting symptoms were right upper quadrant pain 11(64.7%), followed by jaundice 9 (52.9%), indigestion 7 (41.2%), nausea 6 (35.3%), fever 2 (11.8%), and pruritus 2 (11.8%). 3. According to the Cse-ndes` classification, the cases were categorized into type I 12 cases (70.5%), type Ⅱ 1 case(5.99%), type Ⅲ 2 cases (11.8%), and type Ⅳ 2 cases(11.8%). 4. Open cholecystectomy was applied to nine patients. Three patients who were believed to be unfit for surgery because of high risk were treated by endoscopic approach. There was no procedure-related complication. The Mirizzi syndrome is an unusual complication of gallstone disease. Though accurate diagnosis and cholecystectomy is a rational option, medical treatment can be performed in selected patients who are unfit for surgery.
황연해독탕(黃連解毒湯)이 Hypoxia-reoxygenation에 의해 손상 받은 Mouse Neuroblastoma 2a Cells에 미치는 영향(影響)
안상훈 ( Sang Hoon Ahn ),김종우 ( Jong Woo Kim ),강철훈 ( Chul Hun Kang ),황의완 ( Wei Wan Whang ) 대한한방신경정신과학회 2006 동의신경정신과학회지 Vol.17 No.2
Objective : This study was designed to asses the effect of Hwangryunhaedoktang and herbs on Mouse neuroblastoma 2a cells damaged by hypoxia-reoxygenation. Method : Mouse neuroblastoma 2a (N2a) cells were measured by MTT assay and LDH assay after 48h hypoxia and 6h reoxygenation. Mouse neuroblastoma 2a (N2a) cells were treated by Hwangryunhaedoktang and herbs. Result :1. Hwangryunhaedoktang was effective on LDH assay of hypoxia and reoxygenation.2. All of herbs were generally effective on LDH assay of hypoxia and reoxygenation.In LDH assay of hypoxia, the effects of herbs depended on concentration.In MTT assay of hypoxia, Coptidis Rhizoma and Gardeniae Fructus were effective.In MTT assay of reoxygenation most of herbs were not effective. But Phellodendri Cortex was effective in high concentration. Conclusion : The results imply that Hwangryunhaedoktang and all herbs of it may have protective effect on dementia and aging.
안상훈(Sang Hoon Ahn),유정열(Jung Yul Yoo) 대한기계학회 2008 대한기계학회 춘추학술대회 Vol.2008 No.5
The main obstacle to propel micro/nano robots or particles is high temperature generated by traditional energy sources. To reduce it, many attempts have been made so far but most of them have not proved their effectiveness. One research recommended fascinating idea that flagella bacteria be used as energy source like our ancestors used livestock as energy source. The limitation of this research is random motion. Thus, we suggest one directional motion with Janus particle. For generating Janus particle, we designed a micro channel device. One hemisphere of a droplet includes a fluorescent dye which shows the direction of the particle. The other hemisphere of a droplet includes a chemical attractant for flagella bacteria, Serratia marcescens (S.marcescens) which is known as one of the strongest flagella bacteria. Both sides of Janus droplet include UV initiator for solidification. To harvest Janus particles with micro pipettes, they are released to the site where flagella bacteria, Smarcescens, were incubated. Then we observe directional movement of each particle.
생산과 복지의 제도적 상보성에 관한 비교연구 : 선진자본주의 국가를 중심으로
안상훈(Ahn Sang-Hoon) 한국사회복지학회 2005 한국사회복지학 Vol.57 No.2
본 연구는 복지체제와 생산레짐이 서로 연관성을 지니는지, 만약 연관된다면 어떤 방식으로 조응하는지, 그리고 현대복지국가의 두 가지 목표라고 할 수 있는 생산과 분배에서 어떤 차이를 노정하고 있는지에 관한 경험적 분석이다.<br/> 본 연구의 분석은 크게 두 부문으로 나뉜다. 하나는 Esping-Andersen의 복지체제론에서 이야기되는 세 가지 체제가 생산과 복지의 포괄적 조응을 담아낼 수 있는가에 관한 군집분석이고, 다른 하나는 이러한 세 가지 체제들이 생산과 복지에 관한 다양한 변수들에 있어 통계적인 차이를 보이는지에 관한 일원분산분석이다.<br/> 본 연구의 분석결과는 다음과 같다. 첫째, 군집분석 결과, 자본주의의 다양성에 관한 논의와 세 가지 복지자본체제에 관한 논의는 하나의 분석틀 안에서 소화될 수 있음이 밝혀졌다. 둘째, 일원분산분석 결과, 생산과 복지에 관한 대표적인 변수들이 세 가지 체제 사이에 상당한 차별성을 보임이 확인되었다. 무엇보다 흥미로운 결과는 사민주의, 보수주의, 자유주의 체제들이 유사한 수준의 경제적인 성과를 보이면서도 분배성과에 있어서는 매우 상이한 수준을 지닌다는 점이다. This study empirically examines if there is a certain linkage between the production regimes and welfare systems; and if linked, how they are linked. It also investigates what the different regimes performed in terms of economic growth and redistribution. <br/> As a matter of fact, we have a series of studies that explores structural diversity of production and welfare. However, the existing studies are limited in that they consider only specific facets of the structure, although the structure of welfare capitalism should be studied as a comprehensive whole. This is the gap which this study tries to overcome.<br/> The study is composed of two major parts. The first one is the cluster analysis that examines if Esping-Andersen's notion about three different welfare regime and the thesis of diversity of capitalism can be dealt within a single research framework. The second is the ANOVA analysis investigating if variables of production and welfare are to be statistically different in the trichotomy framework. <br/> According to the result of the analyses, we can find at least two important evidences about institutional complementaries of production and welfare. First, Esping-Andersen's framework is useful to comprehensively deal with production as well as welfare. Secondly, there are statistically different regimes of production and welfare in the context of political economic and social policy variables.<br/> What is the most striking conclusion of the study is that there is no difference among the regimes in terms of the level of economic efficiency; while we can find a huge differences in terms of the level of welfare effectiveness. In conclusion, there is no substantive evidence to argue that welfare is innately antithesis of economic growth.