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신용철,최중대,임경재,심혁호,류창원,양재의,유경열,Shin, Yong-Chul,Choi, Joong-Dae,Lim, Kyoung-Jae,Shim, Hyeok-Ho,Lyou, Chang-Won,Yang, Jae E.,Yoo, Kyung-Yoal 한국농공학회 2005 한국농공학회논문집 Vol.47 No.6
Natural environment of the Wolgokri stream watershed, located in Chuncheon, Gangwon province, Korea, has been well preserved as a traditional agricultural watershed. To analyze characteristics of NPS pollution generated from an mountainous agricultural watershed, the flow and water qualities of the study watershed were monitored and were analyzed to estimate pollution loads. Annual runoff volume ratio was $70.4\%$. Concentrations of T-N, T-p, COD, and TOC were higher when monthly rainfall was between $0\~30mm$ than those when monthly rainfall was between $30\~70mm$. However, the concentrations varied considerably when monthly rainfall was higher than 100mm. The flow weighted mean concentrations(mg/L) of BOD, COD, TOC, $NO_3-N$, T-N, T-P and SS were 1.96, 2.72, 3.32, 1.41, 4.70, 0.187 and 13.36, respectively. The BOD, SS, T-N and T-P loads of July, 2004 were $48\%,\;17\%,\;51\%\;and\;32\%$ of annual load, respectively. The BOD, COD, TOC, $NO_3-N$, T-N, T-p, and SS loads (kg/ha) from Mar. 2004 to Apr. 2005 were 19.09, 26.55, 32.39, 13.85, 45.92, 1.887 and 130.18, respectively. The highest concentrations of BOD, NO3-N, T-N, T-p, SS, COD and TOC were found before the flow reached the peak runoff, possibly due to the first flushing effect. Generally, pollution loads of the Wolgokri watershed were not that significant. Phosphorus load, however, was higher enough to cause eutrophication in the receiving water body It was recommended that best management practices need to be implemented to reduce phosphorus sources.
증례 : Parvovirus B19 감염에 의한 혈구탐식림프조직구증 1예
심혁 ( Hyeok Shim ),김현정 ( Hyun Jung Kim ),이영진 ( Young Jin Lee ),박무림 ( Moo Rim Park ) 대한내과학회 2007 대한내과학회지 Vol.72 No.4
저자들은 발열을 주소로 내원한 평소 건강하던 16세 남자 환자에서 양측 경부 및 겨드랑이 림프절, 간, 비장종대, 범혈구감소증, 골수흡인검사에서는 핵내 봉입체가 있는 거대 전적혈모구와 혈구세포를 탐식하는 조직구의 증가, 항Parvovirus B19 IgM 항체와 중합효소연쇄반응 양성소견으로 Parvovirus B19의 감염에 의한 혈구탐식 림프조직구증으로 진단하였고, 스테로이드 및 IV immunoglobulin의 보존적 치료에 의해 회복된 증례를 보고하는 바이다. Hemophagocytic lymphohistiocytosis is an unusual syndrome that`s characterized by fever, hepatosplenomegaly, cytopenias, hypertriglyceridemia, hypofibrinogenemia and pathologic finding of hemophagocytosis in the bone marrow and other tissues. A previously healthy 16-year-old male was admitted because of fever. The cervical and axillary lymph nodes, liver and spleen were palpable. CBC revealed pancytopenia with a decreased reticulocyte count, and the bone marrow aspiration smear showed the presence of giant pronormoblasts with intranuclear inclusion bodies and an increased number of histiocytes that were engulfing blood cell. IgM antibody against Parvovirus B19 and PCR for Parvovirus B19 were positive. Thus, he was diagnosed with hemophagocytic lymphohistiocytosis that was caused by Parvovirus B19 infection. Parvovirus B19 is an agent rarely associated with hemophagocytic lymphohistiocytosis, and in most cases it occurs in those patients with an underlying disease. We report here on a case of hemophagocytic lymphohistiocytosis associated with acute Parvovirus B19 infection in healthy male. (Korean J Med 72:433-436, 2007)
클라인펠터증후군 환자에서 진단된 11q23 재배열을 동반한 급성 골수성 백혈병 1예
정영훈 ( Young Hoon Jeong ),심혁 ( Hyeok Shim ),이영진 ( Young-jin Lee ),박무림 ( Moo Rim Park ) 대한내과학회 2016 대한내과학회지 Vol.91 No.1
저자 등은 27세의 클라인펠터증후군 환자에서 진단된11q23의 재배열을 동반한 급성 골수성 백혈병 국내 첫 증례를 경험하였다. 현재 클라인펠터증후군이 급성 골수성 백혈병의 발생에 영향을 주는지에 대해서는 논란이 있는 상태이다. 하지만 지금까지 보고된 클라인펠터증후군에서 발생한급성 골수성 백혈병의 진단 당시 나이가 일반인구 집단에 비해 낮은 점은 일반인구 집단에서 발생한 급성 골수성 백혈병과는 다른 특성을 가질 수 있다는 점을 시사한다. 따라서 두질환과의 관계에 대한 여러 가지 의문점을 해결하기 위해서는 좀더 체계적이고 많은 조사 대상이 포함된 연구가 필요할것으로 보인다. Klinefelter syndrome is usually characterized by eunuchoidism, gynecomastia, small testes, infertility, elevated gonadotropins, mental retardation, and a constitutional extra X chromosome. Several reports have suggested an association between leukemia and Klinefelter syndrome, although two cohort studies failed to show a clear association between the two. We report the first Korean case of acute myeloid leukemia with the 11q23 rearrangement in a 27-year-old man with Klinefelter syndrome. (Korean J Med 2016;91:75-78)