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      • KCI등재후보

        비궤양성 소화불량증 환자의 아형분포에 대한 연구

        성인경(In Kyung Sung),강인구(In Ku Kang),심승철(Seung Chul Shim),김종필(Jong Pil Kim),이기창(Kee Chang Lee),손정일(Chong Il Sohn),정철헌(Chul Hun Jung),박동일(Dong Il Park),이종철(Jong Chul Rhee) 대한내과학회 1994 대한내과학회지 Vol.46 No.3

        N/A Objectives: It has been proposed that patients with non-ulcer dyspepsia can be classified into symptom subgroups. Subgroups were as follows; those with symptoms suggestive of peptic ulceration (ulcerlike dyspepsia), those with gastric stasis (dysmotilitylike dyspepsia), those with gastroesophageal reflux (refluxlike dyspepsia), and the remainder (unspecified dyspepsia). Methods: The study population consisted of 306 patients with non-ulcer dyspepsia admitted to or attending to Hanyang University Hospital from the beginning of Feb. 1990 to the end of August 1992. We evaluated the gastrointestinal symptoms and measured gastric emptying time for 150min using radionuclide scintiscan of an 99mTc-labeled chicken liver. Results: 1) A total of 306 patients with diagnosed to non-ulcer dyspepsia, 54% had dysmotilitylike dyspepsia, 16% had ulcerlike dyspepsia, 2% had refluxlike dyspepsia and 10% had unspecified dyspepsia. 2) A total of 148 non-ulcer dyspepsia patients with normal gastric emptying time, 48% had dysmotilitylike dyspepsia, 19% had ulcerlike dyspepsia, 2% had refluxlike dyspepsia and 10% had unspecified dyspepsia. 3) A total of 158 non-ulcer dyspepsia patients with delayed gastric emptying time, 61% had dysmotilitylike dyspepsia, 14% had ulcerlike dyspepsia, 2% had refluxlike dyspepsia and 9% had unspecified dyspepsia. 4) Dysmotilitylike dyspepia was more commonly present in patients with delayed gastric emptying time than in patients with normal gastric emptying time(p<0.05) 5) There was a slight female predominance (1:1.3 male-female ratio) in non-ulcer dyspepsia patients with normal gastric emptying and peak incidence was 40 to 49 years of age (40%). 6) There was a female predominance (1:1.9 male-female ratio) in non-ulcer dyspepsia patients with delayed gastric emptying and peak incidence was 40 to 49 years of age(42%). 7) A total of non-ulcer dyspepsia patients, 35% had irritable bowel symptoms and the frequency of accompanied irritable bowel symptoms was statistically significant difference between the patients with normal gastric emptying time (46%) and the patients with delayed gastric emptying time (26%)(p<0.01). Conclusion: Among the non-ulcer dyspepsia patients in Korean, dysmotilitylike dyspepsia was most common subgroup and the refluxlike dyspepsia was very rare and 35% had irritable bowel syptoms.

      • KCI등재

        항인지질항체 증후군을 동반한 복합 교원성 질환

        이제경 ( Je Kyung Lee ),정성수 ( Sung Soo Jung ),유태석 ( Tae Seok Yoo ),장대국 ( Dae Kook Chang ),심승철 ( Seung Chul Shim ),고희관 ( Hee Kwan Koh ),김태환 ( Tae Hwan Kim ),전재범 ( Jae Bum Jun ),이인홍,배상철 ( Sang Cheol Bae ) 대한류마티스학회 1998 대한류마티스학회지 Vol.5 No.2

        The presence of antiphospholipid antibodies in systemic lupus erythematosus (SLE) and the primary antiphospholipid antibody syndrome(APS) are well-known risk factors for thrombosis. However, aCL associated with rheumatic diseases other than SLE or primary APS tend to be in low prevalence and low titer, and unassociated with clinical complications. We experienced a 31-year-old female patient with painful swelling, purpura, and intermittent claudication of both lower extremities, moderate thrombocytopenia, and persistent positive antiphospholipid antibodies(43 GPL of aCL, positive LAC). Four years prior to admission, she had been diagnosed at our hospital as a mixed connective tissue disease because of positive anti-nRNP, Raynaud`s phenomenon, swollen hands, polyarthritis, sclerodactyly. After anticoagulant therapy, she experienced remarkable symptomatic improvement. We report an unusual case of antiphospholipid antibody syndrome in mixed connective tissue disease with a review of the literature.

      • SCOPUSKCI등재

        내시경적 위장관 용종 절제술 60예의 임상적 고찰

        박경남,이민호,윤석진,기춘석,이종철,심승철,함준주 대한소화기내시경학회 1993 Clinical Endoscopy Vol.13 No.2

        Advances in fiberoptic endosoarpy have improved diagnostic capabilities and management in patients with gastrointnatinal polyps. The gastrointestinal polyp is a premalignant lesion in varying dagrees according to size, pathology, and location. Endpecopic polypetomy has long been considered as a safe and effective method for removal of polyp. Sixty endoscopic gastrointestinal polypectamies wire doe in 53 patients who visited Hanyang University Hospital from 1984 to 1990, and the clinical characteristics including histopathology were evaluated. The results obtained were as follows; 1) Most patients were in fifth decade. The ratio of male to female was 1 :1.52 2) 40 gastric polyps were found among 41,300 gastrofiberscopies(0.09%) and 20 colonic polyps were found among 1,200 colanofiberscopies(1.6%). 3) The removed gastroduodenal polyps were mostly below 0.5cm in size(37.5%) and colonic polyps wire mostly 1.0 cm to 2.0 cm in size(25% ). 4) The number of single polyp was 32(88%) in gastroduadenum and 12(70.5%) in colon. In gastroduodenal polyps, polyps were located on gastric body(20 cases), gastric antrum(18 cases), and duodienal bulb(2 cases), in order of frequency. In colonic polyps, polyps were located on sigmoid colon(10 canes) and rectum(4 cases). 5) Histapathologic examittations revealed that most common type was hyperplastc type(62.5 %) in Bastroduodenal polyps and adenomatous type(40%) in colonic polyps. One case of gastroduadenal polyp and three cases of colonic polyps showed focally malignant change of muscosa. Therefore, endoscopic polypectomy is thought to be important to assess malignant change of gastrointestinal polyps.

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