소적혈구로부터 새로운 헝태의 세포질 포스포리팍제 A2의 동정 및 특성규명

신혜숙(Hae Sook Shin),김하동(Ha Dong Kim),장동훈(Dong Hoon Chang),전형준(Hyung Jun Jeon),유충규(Chung Kyu Ryu),정성윤(Sung Yun Jung),김대경(Dae Kyong Kim) 대한약학회 2001 약학회지 Vol.45 No.4

A Ca2+_dependent PLA2 activity termed Rpla2, was detected in the cytosol of bovine red blood cells (RBCs). The Rplab was characterized as a similar form to Group IV Cpla2, but different in secteral column chromatographic profiles including an anion exchange column.73 examine whether this Rpla2 is different from the well characterized Rpla2, a quinone derivative, BJ5O, was developed and tested for the inhibitory effect on the two PLA2 enzymes. The rPLA2 activity was inhibited by a quinone derivative (BJ5O) with ID50 of 20μM., but had no effect on the cPLA2, suggesting that rPLA2 may be a novel type of cytosolic PLA2 in RBCs.

댄스 동아리 활동에 참여한 청소년의 중독 현상과 정서와의 관계

신혜숙(Hae Sook Shin) 한국사회체육학회 2010 한국사회체육학회지 Vol.0 No.39

This study examined the relation between exercise addiction and emotion in 165 adolescents who were participating inr dance club activities, and drew conclusions as follows. First, with regard to the relation between exercise addiction and the pattern of participation in dance club activities, according to experience in dance club, exercise addiction was significantly more frequent in adolescents with dance experience of `three years or longer` than in those with experience of `less than a year.` According to satisfaction with participation, exercise addiction was significantly more frequent in adolescents who replied `Very satisfied` than in those who replied `Little satisfied`, According to experience in dance competitions, exercise addiction was significantly more frequent in adolescents who participated in dance competitions `three times or more a year` than in those without experience in dance competitions. Second, with regard to the relation between emotional difference and the pattern of participation in dance club activities, according to experience in dance club activities, emotional difference was larger in those with dance experience of `1~3 years` but the difference was not statistically significant. According to satisfaction with participation, emotional difference was significantly larger in adolescents who replied `So-so` than in those who replied `Very satisfied` and according to experience in dance competitions or presentations, emotional difference was significantly larger in adolescents without such experience than in those who participated in dance competitions or presentations `once or twice a year` or `three times or more a year.` Third, in the results of multiple regression on adolescents` addiction to dance club activities and their emotion, a high correlation was observed between addiction and emotion. In addition, exercise addiction appeared to have explanatory power to emotion, and emotion was affected significantly by the sub-factors of addiction `focus on health,` `strong desire,` `withdrawal symptom,` and `interpersonal relation` in their order. With the transition of dance culture over time, adolescents are participating in various dances voluntarily and actively, and creating adolescent-specific cultural society that is even contributing to the globalization of Korean culture. Because excessive absorption and addiction may have a harmful effect on emotion, however, guidance is required for adolescents` participation in dance activities.

무용 전공자들의 역할 수행 및 전문직업적 정체성, 진로 결정과의 관계

신혜숙 ( Hae Sook Shin ) 대한무용학회 2013 대한무용학회논문집 Vol.71 No.2

This study were conclusions as follows. First, the role performance, job identity, and career decision showed significant correlation. Second, job identity and career decision according to sub-factors of role performance, it was found that flexibility, one of subfactors of role performance, significant effects on sense of vocation and self reliance of job identity, feedback of role performance on professionalism of job identity, and making efforts of role performance on sense of vocation, self-reliance and professionalism. Third, career decision according to sub factors of job identity, sense of vocation, selfreliance and professionalism significant effects on career direction.

A Study on the Utilization of Inorganic Sulfur in Chicks

윤재인,신혜숙,신상주,Yoon, Jae-Ihn,Shin, Hae-Sook,Shin, Sang-Joo 생화학분자생물학회 1973 한국생화학회지 Vol.6 No.3

표지된 황산염 유황을 5일령되는 병아리에게 먹여 1주 내지 4주간 계속한 다음 각종조직과 기관으로부터 방사능을 검출하므로써 닭에 있어서 무기 유황 이용에 관하여 실험하였다. 기관에서 추출한 tendomucoid, 식도와 건에서 만든 collagen은 방사능을 시종 검출할 수 있었는바 상당한 차이가 조직간에 그리고 처리간에 나타났다. 이는 이들 조직이 표지된 황산염을 황산염 함유물질에 전입하였음을 시사한다. 위와 비슷한 현상이 날개와 다리의 피부로부터 만들어진 elastin에서도 관찰되었는데 이는 황산염 유황이 cystine 및 methionine 등의 유기 유황으로 전환되었음을 시사한다. 방사능은 실험기간 중 첫주에서 4주까지 깃털과 꼬리털에서도 검출되었다. 이는 무기 유황이 털의 경우 전체 아미노산의 20% 이상을 차지하는 아미노산인 cystine으로 전환 되었음을 결정적으로 시사한다. 제 3주 및 제 4주에는 간장, 신장, 심장 및 흉근으로 만든 균질물에서도 방사능이 검출되었다. A study on the utilization of inorganic sulfur in chicks was carried out with labeled sulfate-sulfur fed to five-day old chicks and radioactiviy was counted for various tissues and organs of chicks after one to four weeks of treatment. Tendomucoid prepared from trachae and collagen made from esophagus and tendon emitted the beta-ray with a considerable variation between tissues and between treatments throughout the investigation indicating that these tissues incorporated labeled sulfate into sulfate-containing compounds. A similar observation was made on the elastin prepared from wing and leg skin suggesting a probable conversion of sulfate sulfur to organic sulfur such as cystine and methionine. The ray was detected from the feather of both wing and tail from the first week till the fourth week of the experiment. This is definitely indicative that inorganic sulfur is incorportated into cystine, an amino acid which alone counts more than 20 per cent of total amino acids in feather. Total homogenates made from liver, kidney, heart and breast muscle during the third and fourth treatments also emitted radioactivity.

닭에 있어서의 무기 유황 이용에 관한 연구

윤재인,신혜숙,신상주 ( Jae Ihn Yoon,Hae Sook Shin,Sang Joo Shin ) 생화학분자생물학회 1973 BMB Reports Vol.6 No.3

A study on the utilization of inorganic sulfur in chicks was carried out with labeled sulfate-sulfur fed to five-day old chicks and radioactivity was counted for various tissues and organs of chicks after one to four weeks of treatment. Tendomucoid prepared from trachae and collagen made from etophagus and tendon emitted the beta-ray with a considerable variation between tissues and between treatments throughout the investigation indicating that these tissues incorporated labeled sulfate into sulfate-containing compounds. A similar observation was made on the elastin prepared from wing and leg skin suggesting a probable conversion of sulfate sulfur to organic sulfur such as cystine and methionine. The ray was detected from the feather of both wing and tail from the first week till the fourth week of the experiment. This is definitely indicative that inorganic sulfur is incorportated into cystine, an amino acid which alone counts more than 20 per cent of total amino acids in feather. Total homogenates made from liver, kidney, heart and breast muscle during the third and fourth treatments also emitted radioactivity.

무용 수업에 참여한 초등학생들의 감성지능과 자기효능감 및 또래 유능성과의 관계

장하나(Ha Na Jang),신혜숙(Hae Sook Shin) 한국사회체육학회 2012 한국사회체육학회지 Vol.0 No.50

This study used the total 223 copies of data as the final analysis by using the significance sampling method after selecting elementary schoolers participating in dance classes as the sampling group. For the data possible to be analyzed from the collected data, multiple regression analysis and the correlation analysis were conducted by using SPSS 18.0 and the results are like below. First, significant correlation is shown in the correlation analysis for the emotional intelligence, self-efficacy and peer competence of the elementary schoolers participated in dance classes. Second, in the result of multiple regression analysis of self-efficacy in accordance with the subordinate factors of emotional intelligence, it has 35% influence on self-efficacy. Especially, “self-awareness” factor, “self-regulation” factor and “synchronization” factor among the subordinate factors of emotional intelligence are shown to have significant relations with self-efficacy. Third, in the result of multiple regression analysis of peer competence in accordance with the subordinate factors of emotional intelligence, it has 47.1% influence on peer competence. Especially, “self-awareness” factor, “petty interpersonal” factor”, “self-regulation” factor and “synchronization” factor are shown to have significant relations with emotional intelligence. Fourth, self-efficacy is shown to have 45.6% influence on peer competence while “self-regulation” “judgment” “competence” “daecheoryeok ”factor among the subordinate factors is shown to have significant relation with peer competence. It is found that dance classes has influence on improving emotional intelligence, self-efficacy and peer competence of elementary schoolers whose egos start to be formed, which means that physical expression activities act as not only providing physical/emotional/social development and infinite imagination, but also improving social/emotional competence which can guarantee children`s happy lives. Thus in order to develop children`s healthy egos, dance classes through physical expression activities are mostly essential education for the growth and development in childhood. They should be formed to provide better educational effects as more studies on this should be conducted in the future.

자연과학분야: 무용과 댄스스포츠 전공별 여중생의 신체구성 및 체력 분석

오수일(Su Ill Oh),신혜숙(Hae Sook Shin),황예선(Ye Seon Hwang) 한국무용과학회 2012 한국무용과학회지 Vol.26 No.-

본 연구는 무용 및 댄스스포츠를 전공으로 한 여자 중학생 14명(무용; 7, 댄스스포츠; 7)을 대상으로 하여 전공별 신체구성 및 체력을 분석하였다. 신체구성 측정을 위해 Inbody 3.0을 이용하여 체중, 체지방량, 체지방률, 제지방량, 체질량지수를 알아보았다. 체력 분석항목은 근력, 근지구력, 순발력, 민첩성, 유연성, 평형성 및 전신지구력으로 하였으며, 각 항목의 측정을 위해 악력계, 윗몸일으키기, 제자리 멀리뛰기, side step 검사, 앉아 윗몸 앞으로 굽히기, 외발서기 및 트레드밀을 이용한 최대산소섭취량으로 하였다. 신체구성 결과, 체중, 체지방량, 체지방량, 제지방량 및 체질량지수의 모든 항목에서 무용전공 집단과 댄스스포츠전공 집단 간의 유의한 차이가 나타나지 않았다(p>.05). 체력에서는 유연성(p<.01), 순발력(p<.01), 민첩성(p<.05), 전신지구력(p<.05)항목에서 무용전공 집단이 댄스스포츠전공 집단에 비해 유의하게 높은 것으로 나타났으며 근력, 근지구력, 평형성에서는 집단 간 유의한 차이가 나타나지 않았다(p>.05). 무용 및 댄스스포츠전공 여자 중학생의 신체구성과 체력간의 상관에서는 체지방량이 전신지구력에 부적 상관을 나타냈으며 30.5%의 영향력을 미쳤다. 체지방률도 전신지구력에 부적 상관을 나타냈으며 33.4%의 영향력을 미치는 것으로 나타났다. 제지방량은 근력에 정적 상관이 있는 것으로 나타났고 44.7%의 영향력을 나타냈다. This study analyzed the body composition and physical fitness of fourteen middle school girls who have been majoring in dance(n=7) and seven majoring in dance sports(n=7) for no less than 2 years. Weight, body fat mass, %fat, lean body mass and body mass index(BMI) were studied using Inbody 3.0 to measure body composition. The items for physical fitness analysis included muscular strength, muscular endurance, power, agility, flexibility, balance and cardiorespiratory and the measurement for each item used dynamometer, sit-up, standing long jump, side-step test, trunk flexion, single leg stance, and VO2max. The results on body composition showed no significant difference between dance group and dance sports group in all items(p>.05). As for physical fitness, dance group showed a significantly higher than dance sports group in flexibility(p<.01), power(p<.01), agility(p<.05),cardiorespiratory(p<.05) and there was no significant difference between two groups in muscular strength, muscular endurance, and balance(p>.05). In terms of the correlation between body composition and physical fitness for middle school girls majoring in dance and dance sports, body fat mass had negative correlation with cardiorespiratory with 30.5 percent of influence. %fat also showed negative correlation with cardiorespiratory with 33.4 percent of influence. Lean body mass had positive correlation with muscular strength with the influence being 44.7 percent.

한국인(韓國人)의 잠복기 상태의 H.A.A.에 관하여

김창균 ( Chang Kyoon Kim ),이건섭 ( Keun Sup Lee ),신혜숙 ( Hae Sook Shin ),김남호 ( Nam Ho Kim ) 대한임상검사과학회 1973 대한임상검사과학회지(KJCLS) Vol.5 No.1

The prevalence of hepatitis associated antigen in Korean of 199 out-patient and 1,501 health populations were studied by means of Agar gel double diffusion technique at St. mary`s hospital, Catholic Medical CoIlege. The results are as follows: 1. The H.A.A. showed positive results in 5.3% (89 of 1700 case) and this was much higher than the prevalence in other countries. 2. The H. A. A. distribution was more frequentin 21-30 years old healthy groups. This indicated that active age groups had higher chance of infections than the other age groups. 3. The exact mode of transmission remains obscure but scarification may have important role. 4. The relationship between the occurence of H. A. A. positivity and blood transfusion revaled more higher prevalence in multiple transfusion cases. 5. The positive rate of H. A. A showed 50% on 5th to 9th day and 20th to 29th day after blood transfusion respectively.

수지침요법이 월경전후기 불편감 완화에 미치는 효과

조결자 ( Kyoul Ja Cho ),문희자 ( Heui Ja Moon ),박신애 ( Shin Ae Park ),강현숙 ( Hyun Sook Kang ),신혜숙 ( Hae Sook Shin ),정숙자 ( Sook Ja Chung ),이은미 ( Eun Mi Lee ) 경희대학교 동서간호학연구소 2001 동서간호학연구지 Vol.6 No.1

The purpose of this study was to identify the effect of hand acupuncture for reduction of dysmenorrhea. 71 female middle school and high school students were selected as subjects from April to May 2001, among which 38 students consisted of the experimental group while 22 students were the control group by convenient assignment. The experimental group participated in hand acupuncture treatment. The experimental treatment was to puncture corresponding points(A4, A5, J1, J3, J23, H2, F7) on both the palm and back of a hand with disposable acupuncture needles and to remove needles after 20-30 minutes` recess during which the subjects reposed themselves on bed. The collected data were processed using the SPSS PC Program and analyzed using χ2 test and t-test. The results of this study were as follows 1. The symptoms of premenstrual syndrome have decreased, but no significant differences were statistically observed between hand-acupunctured group and non-hand acupunctured group. 2. Subjective pain degree has decreased after hand acupuncture. 3. As for objective pain degree, a significant reduction in voice change was observed between two groups. Facial expressional changes and perspiration degree reduced but showed no significant statistically changes between two groups. 4. Comfort has increased after hand acupuncture. These results suggest that the hand acupuncture therapy works effectively on easing menstrual pain and symptoms as well as partially on reducing discomfort. It is particularly efficacious for a reduction in subjective pain and facial expressional changes in positive respect. Therefore the hand acupuncture therapy can be considered as an independent nursing intervention for dysmenorrhea reduction.

두경부 암환자의 항암화학요법에 따른 삶의 질 변화

신혜숙,박혜자,박명희,연기순,김훈교,문한림,송혜향 가톨릭대학교 가톨릭대학교 간호대학 호스피스 교육연구소 1999 호스피스논집 Vol.4 No.-

The purpose of this study was to assess the changes in quality of life wish elapse of chemotherapy in head and neck cancer patients. This study was a longitudinal descriptive design. The subjects were 9 patients who had stage III and stage IV head and neck cancer and received neoadjuvant cisplatin and 5-fluorouracil chemotherapy. Linear Analogue Self Assessment Scale (LASA) of the QOL which it includes eleven items(seven physical items appetite, nausea/vomiting, physical well-being, vigor activity, energy, sleepiness, fatigue and four mental items anger, anxiety, depression & vital power) were used to assess the quality of life eleven times(once in the prechemotherapy period and from the 1st day to 10th day postchemotherapy). The means of scores at each time were analyzed by repealed measures of ANOVA and Bonferroni multiple comparison method. The results are as follows : 1. The degree of appetites decreased significantly on the period between third and sixth day compared with that of appetites on the prechemotherapy day (p<0.001). 2. The degree of physical well-being decreased significantly on the period between first and fifth day compared with that of physical well-being on the prechemotherapy day (p<0.001). 3. The degree of nausea/vomiting decreased significantly on the period between first and fourth day compared with that of appetites on the prechemotherapy day (p<0.001). 4. The degree of anger decreased significantly on the second, fourth, eighth and ninth day after chemotherapy compared with that of anger on the prechemotherapy day(p<0.001). 5. The degree of fatigue decreased significantly on the fourth day compared with that of fatigue on the prechemotherapy day(p<0.001). 6. The increment of nausea/vomiting and poor appetite started on the 2.89th day and 3.67th day after chemotherapy, respectively. 7. The increment of sleepiness started on the 2.56th day after chemotherapy. 8. The increment of depression and anxiety started on the 2.33th day and 3.33th day after chemotherapy, respectively. 9. The lowest degrees of nausea/vomiting and poor appetite were 37.00±17.9 % and 28.64±14.94 % after chemotherapy compared with those of nausea/vomiting and poor appetite on the prechemotherapy day, respectively. 10. The lowest degrees of anger and vigor activity were 48.12±28.3 % and 39.83±24.9 % after chemotherapy compared with those of anger and vigor activity on the prechemotherapy day, respectively. 11. The recovery rates of eight items of quality of life (appetite, vigor activity, energy, fatigue, anger, anxiety, depression & vital power) were shown to reach a peak on the tenth day after chemotherapy and be reached to almost 84 % compared with those of quality of life on the prechemotherapy day. 12. The recovery rates of physical well-being and sleepiness were shown to reach to 67.75 % and 95.68 % on the 10th day after chemotherapy compared with those of physical well-belong and sleepiness on the prechemotherapy day. 13. The recovery rates of seven physical items were faster than those of four mental items on the 10th day after chemotherapy. In conclusion, it is suggested that nursing care strategies to improve the quality of life in patients with chemotherapy would be established both physically and mentally, and be extended at least ten days when patients stayed their home after chemotherapy.