X-ray상 경추 추체간 간격과 CT상 경추 추간판 탈출증의 상관관계에 대한 고찰

신우석 ( Woo Suk Shin ),정동훈 ( Dong Hoon Jung ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2015 한방재활의학과학회지 Vol.25 No.4

Objectives To investigate the relationship between cervical intervertebral space narrowing in the X-ray and HIVD level of cervical spine in the CT image. Methods We studied 101 subjects who were taken cervical spine X-ray and CT. Intervertebral space were measured at the anterior, middle and posterior portion of each cervical disc in the X-ray. Considering individual difference, intervertebral space was set as value divided by upper width of lower vertebral body. We analyzed statistically adjusted intervertebral space of normal group and herniated disc group using student’ t t-test. Results Intervertebral space of cervical spine was narrowed in the herniated disc group. But there was no significant difference at C2∼C3. Conclusions We found that narrowing intervertebral space of cervical spine is associated with herniated disc. Further clinical observation is needed. (J Korean Med Rehab 2015;25(4):75-81)

PubMed 검색을 통한 요추 추간판 탈출증의 침치료 연구 동향

신우석 ( Woo Suk Shin ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2014 한방재활의학과학회지 Vol.24 No.4

ObjectivesThe purpose of this study is to research current trends of acupuncture treat-ment of lumbar herniated intervertebral disc using the PubMed database.MethodsWe set up the search strategy and investigated clinical trials on acupuncture treatment of lumbar herniated intervertebral disc through PubMed search. This study ana-lyzed previous researched papers published from January 1st, 2000 to April 30th, 2014, and classified them by publication year, journal names, types of literature, treatment meth-ods and evaluation scales. To assess the quality of the reviewed literature, randomized controlled trial (RCT) studies were assessed by Cochrane`s risk of bias (ROB) tool and non-RCT studies were assessed by risk of bias for non-randomized studies (RoBANS).ResultsWe found 35 studies on the acupuncture treatment of lumbar herniated inter-vertebral disc. Papers on this topic have been published, on average, three to four times annually in 9 journals since the mid-2000`s. The journal with the largest number of pub-lications was Chinese Acupuncture & Moxibustion, and most of articles were classified as RCT. Acupuncture treatment was performed individually or together with other treatments. The most frequently used pain evaluation index was visual analogue scale (VAS). The index of effective rate was used frequently but there was a lack of objectivity. In regards to the quality of the studies, outcome assessment in RCT showed that random sequence gen-eration, allocation concealment, and the blinding of participants and personnel increase po-tential of risk of bias. For non-RCT assessment, outcome showed that confounding varia-ble, measurement of intervention were at high risk of bias.ConclusionsIn order to obtain objective clinical evidence of acupuncture treatment of lumbar herniated intervertebral disc, further clinical studies should be designed to minimize the risk of bias, using STRICTA with larger sample sizes. (J Korean Med Rehab 2014;24(4):49-60)

혈액검사 결과를 바탕으로 살펴본 노인 비만 특성 고찰

신우석 ( Woo Suk Shin ),고찬희 ( Chan Hee Kho ),최정은 ( Jeong Eun Choi ),이상욱 ( Sang Wook Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방비만학회 2013 한방비만학회지 Vol.13 No.2

The purpose of this study was to investigate the characteristics in elderly population with obesity by analyzing their blood test. Methods: Included 130 subjects of aged 60 or older went through body composition test, and blood test. We divided them into obesity group and normal group based on body mass index (BMI) results, and then the blood test results were compared between the groups. Results: Forty out of 130 subjects had BMI of 25 or more. Two groups showed significant difference in bilirubin total, alanine aminotransferase (ALT), cholesterol total, triglyceride, high density lipoprotein (HDL), red blood cell (RBC), hematocrite, mean corpuscular hemoglobin concentration, and platelet. All but HDL levels showed significantly higher results in obesity group than normal group. When compared with BMI, blood urea nitrogen, creatinine, ALT, cholesterol total, triglyceride, white blood cell (WBC), and RBC had significant positive correlations. Among those, cholesterol total, triglyceride, WBC, and RBC showed significant difference between two groups, with correlation to BMI. Especially, the average of triglyceride was higher than normal limit in obesity group, whereas it was lower than normal limit in normal group. Conclusions: Triglyceride, cholesterol total, WBC, and RBC are highly related to obese elderly in this study. Old people with obesity need to be careful of cardiovascular and metabolic disease that can be caused by these factors.

경골 파혈산동탕(破血散疼湯)이 골절 생쥐의 골 유합에 미치는 영향

신우석 ( Woo-suk Shin ),( Kira Parichuk ),차윤엽 ( Yun-yeop Cha ) 한방재활의학과학회 2020 한방재활의학과학회지 Vol.30 No.4

Objectives The main purpose of this study was to evaluate the bone healing effect of Pahyeolsandong-tang (PHT)(Poxiesanteng-tang) extract in tibia fracture-induced mice. Methods PHT was extracted using a solution of 35% ethanol in 60°C for 8 hours. Mice were randomly divided into 4 groups (normal, control, PHT 50 and PHT 100). Mice of experimental groups were medicated with PHT 50 or 100 mg/kg for 7 to 21 days. To clarify the effect of bone fracture healing, relative messenger RNA (mRNA) expressions of osteocalcin (OCN), runt-related transcription factor 2 (Runx2), osterix (OSX), Sox9, collagen type Ⅱ alpha 1 chain (Col2a1), receptor activator of nuclear factor kappa-B ligand (RANKL), osteoprotegerin (OPG) were examined. Results In in vitro experiment, relative mRNA expression of OCN, Runx2, Col2a1 was significantly increased in PHT treated group to compare with control differentiation group. In in vivo experiment, relative mRNA expression of OCN, Runx2, OSX, Sox9, Col2a1, RANKL, OPG was significantly increased in PHT treated group. Conclusions This study showed that PHT accelerates bone fracture healing through the activation of osteoclasts and osteoblasts. It was showed that PHT significantly promotes osteoblasts differentiation by osteoblast differentiation markers such as OCN, Runx2, Col1a2. Also it was investigated that PHT had stimulatory effect on osteoblasts function through enhancing OCN, Runx2, OSX, Sox9, Col2a1 and, osteoclasts function through enhancing RANKL and OPG markers. PHT effectively promotes bone fracture healing process through activation of osteoblasts and osteoclasts. (J Korean Med Rehabil 2020;30(4):1-16)

전방머리자세(Forward Head Posture)의 정도와 척추 만곡 변형의 상관관계

정현우 ( Hyun Woo Jung ),신우석 ( Woo Suk Shin ),김두희 ( Doo Hee Kim ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),고연석 ( Youn Seok Ko ),이정한 ( Jung Han Lee ),정원석 ( Won Suk Chung ),신병철 ( Byungcheul Shin ),송윤경 ( 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4

ObjectivesThis study was designed to investigate the correlation between the forward head posture and the spinal alignment.MethodsWe examined the whole spine x-rays of the 144 student sample. We meas-ured the Craniovertebral angle (CVA), Cervical angle (CA), Thoracic kyphotic angle (TKA), lumbar lordosis angle (LLA) and Ferguson`s angle (FA) of the students. We then analyzed the relationship between these angles.ResultsCVA had correlation with CA, but it was weak. There was significant correlation between CVA and TKA. There were no significant correlation among CVA, LLA and FA.ConclusionsAccording to above results, there is a negative relationship between the CVA and the TKA - in that higher CVAs yielded lower TKAs. But CVA had no significant correlation with LLA or FA. (J Korean Med Rehab 2013;23(4):195-202)

비만에 대한 국내 의학계의 최근 연구 동향 분석 -대한비만학회지를 중심으로-

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),김동환 ( Dong Hwan Kim ),정연재 ( Yeon Jae Jeong ),임한빛 ( Han Bit Im ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방비만학회 2013 한방비만학회지 Vol.13 No.1

This study was performed to analyze the recent trend of the studies about obesity in medicine and to provide background for futher studies. Methods: All of the article were selected in "The Korean Journal of Obesity". Search were conducted through "http://kosso.or.kr" with the search word "obesity". Collected articles were classified into clinical study, experimental study, literary study, case report. Results: One hundred eighty four studies were included and analyzed in terms of study design, subject, intervention, period, obesity index and so on. The numbers of clinical studies, literary studies, experimental studies, case reports were respectively 143 (77.7%), 26 (14.1%), 2 (1.1%) and 7 (3.8%). In clinical studies, observational studies were 112 (78.3%) and intervention studies were 31 (21.7%). And most of sample sizes were more than 100 and less than 499. Body mass index, waist circumstance, body fat percent were major criteria of clinical study. Most of the subjects on obesity were about relation with another disease or experimental results and diagnosis. According to classification by the kinds of intervention, diet, exercise, drug, behavior were respectively 22, 18, 8, and 8. More than fourty percent of intervention studies were studied for 12 weeks. Conclusions: To improve the quality of Korean Medicine study for obesity, we need to recruiting big sample size and activate randomized clinical trial.

반하백출천마탕(半夏白朮天麻湯)과 침 치료에 호전을 보인 섭식장애 환자 치험 1예

정동훈 ( Dong Hoon Jung ),신우석 ( Woo Suk Shin ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),최우진 ( Woo Jin Choi ) 한방비만학회 2015 한방비만학회지 Vol.15 No.1

Eating disorders is a significant failure on the dietary behavior, can be distinguished by anorexia nervosa and bulimia nervosa. For the treatment of eating disorders, screening for medical conditions and hospitalizations are needed. Also, medications such as antidepressants may be helpful, and it should be considered a dynamic psychotherapy, cognitive behavioral therapy, and family therapy together. Recently we experienced a 24-year-old woman who was accompanied with binge eating at night, habitual vomiting, dizziness, anorexia, and general weakness. We applied Banhabaeckchulchunma-tang and acupunture treatment during 2 weeks. Through this program, patient``s condition was improved on body mass index and Eating Attitude Test-26.

만성 요통 임상연구에 사용된 설문지 현황 고찰

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),이진원 ( Jin Won Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),고연석 ( Youn Seok Ko ),이정한 ( Jung Han Lee ),정원석 ( Won Suk Chung ),신병철 ( Byung Cheul Shin ),송윤경 ( 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.4

ObjectivesThe aim of this review is to provide fundamental data for low back pain scales which can be used in clinical trial.MethodsWe investigated the latest studies on chronic low back pain via PubMed. And we also investigated domestic studies through “http://oasis.kiom.re.kr”. 95 research pa-pers were analyzed. Scales were classified into pain scale, function scale, generic health status scale and psychological scale.Results1) According to foreign clinical studies, Visual Analog Scale (VAS) and Numerical Rating Scale (NRS) were used 18 times as pain scale. Oswestry Disability Index (ODI) was used 20 times as function scale, Roland-Morris Disability Questionnaire (RMDQ) was 17, and Hannover Functional Ability Questionnaire (HFAQ) was used 3 times. 36-item Short Form Health Survey (SF-36) was used 13 times as generic health status scale, Euroqol-5 Dimentions Questionnaire (EQ-5D) was 11, and 12-item Short Form Health Survey (SF-12) was used 3 times. Fear-Avoidance Beliefs Questionnaire (FABQ) was used 9 times as psy-chological scale, Pain Catastrophizing Scale (PCS) and Tampa Scale for Kinesiophobia (TSK-R) both were used 3 times. 2) According to domestic clinical studies, VAS was used 37 times as pain scale, NRS was 11, and Short Form McGill Pain Questionnaire (SF-MPQ) was used 6 times. ODI was used 30 times as function scale, RMDQ was 2 times only. SF-36 was used once as generic health status scale and Beck’s Depression Inventory (BDI) was used 3 times as psychological scale.ConclusionsWe recommend VAS or NRS as a measure to evaluate pain, and ODI as a measure to evaluate functional disability. And we also recommend SF-36 or SF-12 and EQ-5D as a measure to evaluate generic health status. Finally, we recommend FABQ for use in measuring psychological scale. (J Korean Med Rehab 2013;23(4):95-115)

비만 치료 한약 무작위 대조 임상시험에서의 음식 섭취량과 운동량 실태분석

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ),송윤경 ( Yun Kyung Song ),안민윤 ( Min Youn Ahn ),고성규 ( Seong Gyu Ko ) 한방비만학회 2013 한방비만학회지 Vol.13 No.2

The objective of this study was to analyse the methods being used to control food intake and physical activity in RCTs of human obesity. Methods: A total of 21 randomized controlled trials (RCTs) were investigated. Nine of which were domestic studies from "http://oasis.kiom.re.kr" and the other of which were foreign studies from systematic reviews of RCTs on herbal medicine for treatment of human obesity. Results: According to domestic studies, "low calorie diet" were recommended in five cases of the domestic studies , "maintain current dietary habit" were recommended in two and no information on diet was two. Considering the seven cases where the information on diet was available, patients`` food intake were checked at every visit in six cases. Only two cases among the six had been dropped owing to the violation of dietary habit by patients. Exercises were prohibited in two cases, "maintain current level of phisical activity" were recommended in three cases and, from the rest, no information was available. The level of physical activity were not strictly controlled by any means hence no drop out. According to foreign studies, "low calorie diet" were recommended in two cases, "very low calorie diet (less than 700 kcal/day)" in one case, "maintain current dietary habit" in two cases, "do not eat fat" in two cases and no information was available in the rest five cases. Exercises which concerns spending about 300 kcal/day was recommended in one case, "moderate exercise" were recommended in three cases, "maintain current level of physical activity" were recommended in three cases and no information available in the rest five cases. Conclusions: In order to improve the accuracy of RCT, for the dietary side, researchers should record patient food intake at every visit by means of 24-hour dietary recall methods. This can be supplemented by multiple choice survey that are designed to help patients to diagnose themselves more accurately leading to less bias. For the exercise side, it is highly recommended to confine the exercises to walking only so as to quantify the amount of physical activity more easily by using pedometer.

해독요법 중 커피관장을 적용한 죽상경화증의 치험 1례

김두희 ( Doo Hee Kim ),신우석 ( Woo Suk Shin ),정현우 ( Hyun Woo Jung ),정준교 ( Jun Kyo Jung ),이진원 ( Jin Won Lee ),박원형 ( Won Hyung Park ),차윤엽 ( Yun Yeop Cha ) 한방재활의학과학회 2013 한방재활의학과학회지 Vol.23 No.2

This study was performed to report the effect of coffee enema among detoxification Therapy on atherosclerosis.Russian patient was treated by coffee enema, acupuncture, herbal medicines, exercise, cupping, korean physical therapy, chuna manipulation treatment and moxibustion. The state of patient was measured by Infrared Thermography, Blood Vessel Stasis Test and Minnesota Nicotine Withdrawal Scale.After treatments, both feet temperature were increased. And index of indicating the occlusion of the lower body was improved. Also, Minnesota Nicotine Withdrawal Scale scores were improved. It means the patient was successful at non-smoking during hospitalization. These results suggests that atherosclerosis was improved. According to above results, coffee enema was effective to improve the atherosclerosis. More studies should be followed.