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Cetraxate 가 흰쥐 위액분비에 (胃液分泌) 미치는 경향
이인수,이상재,신순현,이기환,김종숙 ( In Soo Rhee,Sang Jea Lee,Soon Hyun Shin,Ki Whan Lee,Chong Sook Kim ) 대한소화기학회 1980 대한소화기학회지 Vol.12 No.1
The present study was done to evaluate the effect of cetraxate on the gastric secretion of rats with pylorus ligation. We determined the gastric volume, acid output, total protein, mucoprotein and pepsin concentration of gastric juice 24 hours after administration. The following results were obtained. The gastric volume was decreased than control group. 2. The acid output was decreased than control group. The total protein and mucoprotein were markedly increased in spite of low dosage administration of cetraxate. 4. The pepsin concentration was not changed.
고창순 ( Chang Soon Koh ),이문호 ( Mun Ho Lee ),김용일 ( Yong Il Kim ),서동진 ( Dong Jin Suh ),신순현 ( Soon Hyun Shin ),정홍근 ( Hong Keun Chung ) 대한내과학회 1972 대한내과학회지 Vol.15 No.5
A case of von Gierke`s disease in a seventeen-year-old boy is presented. Clincal features were characterized by growth retardation, & abdominal distension due to marked hepatomegaly, accompanying hypoglycemia, epinephrine-resistant blood sugar level, hyper
당뇨병 환자에 있어서의 혈청 보체 C3 , C4 에 관한 연구
김용성(Yong Seong Kim),서양관(Yang Kwan Seo),오연상(Yeon Sang Oh),신순현(Soon Hyun Shin) 대한내과학회 1989 대한내과학회지 Vol.36 No.2
N/A Complement is required for the final step of the humoral immune process that leads to pancreatic islet cell damage. Recently low serum C4 levels were reported in insulin-dependent diabetes and this might be due to either complement consumption or phenotypic variation. To study the differential levels of the complement system in patients with diabetes mellitus, we measured the serum C3 and C4 levels in 5 patients with insulin dependent diabetes (Type 1), 14 patients with non-obese non-insulin dependent diabetes (Type IIa) and 14 patients with obese non-insulin dependent diabetes (Type IIb). The results were as follows: 1) The serum C3 and C4 levels in the control group were 85.4±8.16 mg/dl and 44.1±8.31 mg/dl respectively. 2) The serum C3 levels in Type I, Type Ila and Type IIb diabetics were not significantly different from that in the control group (p<0,1). 3) The serum C4 levels in Type I diabetics and Type IIa diabetics were 26.9±8.72 mg/dl and 32.2±10.9 mg/ dl, respectively, which were significantly lower than that in the control group (p<0.01, p<0.05, resepectively). However, in Type IIb diahetics, it was not significantly lower than that in the control group (p<0.1). 4) The serum C4 levels were not different between groups with or without diabetic complications, but sereum C3 levels in the groups with diabetic complications were higher than that in the group without diabetic complications (p<0.01). These results showed that there was a significant decrease in serum C4 levels in Type I and Type IIa diabetes mellitus. We suggested that pathogenic similarities were presented between Type I and Type IIa diabetes mellitus in the process of complement systems but further study will he required.