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송현철 ( Hyun Chul Song ),황인택 ( Inteck Whoang ),최광남 ( Kwang Nam Choi ) 한국인터넷정보학회 2009 인터넷정보학회논문지 Vol.10 No.4
본 논문에서는 영상 내 객체들의 카테고리 분석을 위해 연구된 PLSA를 기반으로 특이점에 가중치를 부여하여 보다 유사한 카테고리 간에 인식 성능을 향상시키는 접근법에 대하여 연구하였다. PLSA는 문서기반의 정보검색 분야로부터 소개된 기법으로, 약한 수준의 비감독 방법임에도 불구하고 인상적인 인식성능을 보여준다. 그러나 비슷한 특징점 분포를 보이는 유사한 카테고리 간의 객체 카테고리 인식에 대해서는 비교적 낮은 성능을 보인다. 본 연구에서는 카테고리간의 비교실험을 통해 각 특징점에 대하여 가중치를 부여한 PLSA를 적용하여 유사한 객체 간의 카테고리 인식 가능성을 살펴보았다. 실험에서는 기존의 PLSA 기법과 제안한 가중치를 부여 PLSA 기법을 각각 적용하여 그 성능을 비교하였다. 본 연구에서는 기존 PLSA기법에서는 비교적 낮은 인식률을 보인 유사한 카테고리 인식에 대하여 실험 결과를 통해 가중치를 부여한 PLSA 기법이 보다 향상된 성능을 보임을 확인하였다. In this paper we propose a new approach that recognizes the similar categories by weighting distinctive features. The approach is based on the PLSA that is one of the effective methods for the object categorization. PLSA is introduced from the information retrieval of text domain. PLSA, unsupervised method, shows impressive performance of category recognition. However, it shows relatively low performance for the similar categories which have the analog distribution of the features. In this paper, we consider the effective object categorization for the similar categories by weighting the mainly distinctive features. We present that the proposed algorithm, weighted PLSA, recognizes similar categories. Our method shows better results than the standard PLSA.
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송현철(Hyun Chul Song),최광남(Kwang Nam Choi) 한국정보과학회 2007 한국정보과학회 학술발표논문집 Vol.34 No.1C
영상 내 사물들의 카테고리를 인식하는 연구는 시각적 영상처리와 연관된 다양한 분야에서 활발히 진행되고 있다. 객체 범주화(Object Categorization)는 가정과 같은 실내에서 책상, 의자, 컵, 주전자 등의 다양한 사물들을 구분하여 인식하는데 중요한 역할을 할 수 있다. 본 논문에서는 최근 영상 내 객체들의 카테고리 분석을 위해 연구된 PLSA를 기반으로 특이점에 가중치를 부여하여, 보다 유사한 카테고리 간에 인식 성능을 향상시키는 접근법에 대하여 연구하였다. PLSA는 문서기반의 정보검색 분야로부터 소개된 기법으로, 약한 수준의 비감독 방법임에도 불구하고 인상적인 인식성능을 보여준다. 그러나 비슷한 특징점 분포를 보이는 유사한 카테고리 간의 객체 카테고리 인식에 대해서는 비교적 낮은 성능을 보인다. 본 연구에서는 카테고리간의 비교실험을 통해 각 특징점에 대하여 가중치를 부여한 PLSA를 적용하여 유사한 객체 간의 카테고리 인식 가능성을 살펴보았다. 실험에서는 기존의 PLSA 기법과 제안한 가중치를 부여 PLSA 기법을 각각 적용하여 그 성능을 비교하였다. 본 연구에서는 기존 PLSA 기법에서는 비교적 낮은 인식률을 보인 유사한 카테고리 인식에 대하여 실험 결과를 통해 가중치를 부여한 PLSA 기법이 보다 향상된 성능을 보임을 확인하였다.
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토끼 하치조신경 전위술 후의 신경 및 신경주변조직 변화 관찰을 위한 예비 실험
송현철(Hyun Chul Song) 대한구강악안면외과학회 1999 대한구강악안면외과학회지 Vol.25 No.4
Purpose : The purpose of this study was 1) to find nerve damage after inferior alveolar nerve transposition and 2) to examine whether the soft tissue or bone changes around the nerve produce the compression to the nerve in the healing period. Materials and Method : Inferior alveolar nerve was exposed through the bony window and the scratch was made in the bone to be thought as the inferior alveolar canal. Suture was made after the nerve was repositioned. The nerve and surrounding tissues were examined with the light micioscope and the fluorescent microscope before surgery and at 1 month, 3 months, and 5 months after surgery. Results : After surgery, the epineurium was damaged and the nerve was divided to several fascicles covered with the perineurium The newly formed fibrous connective tissue and vessels were seen around fascicles. There was new bone formation. However the nerve was not compressed by the connective tissue or the new bone. Conclusion : The results of this study suggest that neurosensory disturbances after inferior alveolar nerve transposition are resulted by the direct trauma in surgery rather than the compression to the nerve by the scar or new bone formation in the healing period.
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타이타늄 임프란트 골유착시 TGF-$\beta$와 IGF-I의 발현
이인웅,송현철,지유진,Lee, In-Woong,Song, Hyun-Chul,Jee, Yu-Jin 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.2
Many of the molecular and genotypic events taking place at the osteoblast cell level during bone-implant integration are still largely unknown. The objective of this study was to examine expression patterns of TGF-$\beta$ and IGF-I related genes during bone-implant integration. Titanium implants with machined surface were placed into 8 rabbit tibias. At 3rd, 7th, 14th, 28th day after implantation, the expression pattern of TGF-$\beta$ and IGF-I genes in bone with or without implant was examined using reverse transcriptase-polymerase chain reaction (RT-PCR). At the same time, histomorphometric analysis was evaluated, respectively. The bone-to-implant contacts (BIC) of experimental groups were 5.2%, 6.2%, 6.6%, 24.6% at 3rd, 7th, 14th, 28th day. This indicated that newly formed bone increased at the implant surface in bone marrow space after implantation. The expressions of TGF-$\beta$ and IGF-I were higher in implantation groups than untreated control groups during all experimental days. The increased expression of TGF-$\beta$ and IGF-I genes may be associated with the increased bone-to-implant contact. This result provided the evidence for existing biologic differences in tissue response after implantation and helped us to understand molecular biologic processes in tissue-implant integration.
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타이타늄 임프란트 주위 골유착 관여 유전자의 발현: BMP2, BMP4
심정환,지유진,송현철,Shim, Cheong-Hwan,Jee, Yu-Jin,Song, Hyun-Chul 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.4
After dental implant are planted into their bony site among the various growth factors associated with bone formation. BMP is expressed in the bone surrounding the implant fixture. By taking a close look at BMP2, BMP4 which are growth factors that take put in bone formation, its histologic features and radiographic bone healing patterns we would like to examine the mechanism of osseointegration. We randomly used 8 male and female house rabbit amd used diameter 5 mm height spiral shaped implants(Ostem, Korea) for animal use handled as a resorbable blast machined(RBM) surface and machined surface. 2group were formed and each group had RBM surface and machined surface implant or a simple bone cavity. After 3, 7, 14 and 28 days post surgery 2 objects were sacrificed from each group and histologic specimens were acquired. RT-PCR analysis was conducted and after H&E staining the extent of osseointegration was measured applying a histologic feature and histomorphometric analysis program. Quanitity one -4.41(Bio-Rad, USA) was used after scanning the PCR product image of the growth factors manifested in each group. According to the histomorphometric features the RBM, Machined surface group showed increased contact between bone and implant surface at 3, 7, 14 and 28 days after surgery. The BMP2 level increased in both experiment groups but remained unchanged in the contrast group. BMP4 levels stayed steady after the early post implantation period for RBM but showed decreased in the machined surface group and contrast group. The amount of contact between bone and implant surface increased with the passage of time. BMP2, BMP4 were expressed in both experimental group and contrast group. These growth factors play a role in osseointegration of implant.
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가토 하악골에서 신연 골형성술시 신연속도에 따른 TGF-$\beta$1, IGF-I, bFGF의 발현
신선아,지유진,송현철,Shin, Sun-A,Jee, Yu-Jin,Song, Hyun-Chul 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.3
Distraction osteogenesis is a technique of lengthening bone including soft tissue by gradual separation of surgically divided bone surfaces. Although the biomechanical, histological, and ultrastructural changes associated with distraction osteogenesis have been widely described, the molecular mechanisms governing the formation of new bone in distracted bone segments remain largely unclear. However, such information has significant clinical implications because it may enable targeted therapeutic manipulations designed to accelerate osseous regeneration. The purpose of this study was to evaluate the expression of TGF-$\beta$1, IGF-I and bFGF in distraction osteogenesis according to different distraction rates in a rabbit's mandible. When twenty-four adult rabbits underwent open osteotomy between the premolar and mental foramen, an external bilateral distraction device was applied. Latency was allowed for five days before distraction. Three different distraction rates were 0.7 mm/day (A, n=8), 1.4 mm/day (B, n=8) and 2.4 mm/day (C, n=8). The distraction device was activated with the same distraction rhythms of twice a day until 4.9 mm (A & B group) and 8.4 mm (C group) length gains was achieved. The animals were sacrificed at postoperative 3, 7, 14 and 28 days. The bony specimens were stained with H&E for histologic examination, and RT-PCR analysis was done for the identification of the expression of TGF-$\beta$1, IGF-I and bFGF. The results obtained from this study were as follows : The 0.7 mm/day and 1.4 mm/day distraction rate groups were shown to improve regenerative bone formation on radiographic and histologic examination. Also, TGF-$\beta$1, IGF-I and bFGF expression increased in the 0.7 mm/day and 1.4 mm/day distraction rate groups. But the 2.4 mm/day distraction rate group specimen was different with adjacent normal bone and hardly expressed of growth factors. These findings suggest that improved new bone formation in the 0.7 mm/day and 1.4 mm/day distraction rates is associated with enhanced expression of TGF-$\beta$1, IGF-I and bFGF by mechanical tension stress. Additionally, the 0.7 mm/day and 1.4 mm/day distraction rate groups were significantly different from the 2.4 mm/day distraction rate group in the expression of growth factors. According to the above results, it seems possible to apply a distraction rate of up to 1.4 mm/day a day in rabbit's mandible. And further studies are needed to evaluate growth factors of TGF-$\beta$1 and IGF-I, which are excellent in expression.
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