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흰쥐에서 경부 교감신경절제술이 안압의 일차변동에 미치는 영향
임남기,김태형,송준경,유지명.Nam Kee Lim. M.D.. Tae Hyung Kim. M.D.. Joon Kyeong Song. M.D.. Ji Myong Yoo. M.D. 대한안과학회 2008 대한안과학회지 Vol.49 No.11
Purpose: The present study was undertaken to determine the 24-hour pattern of intraocular pressure (IOP), and to reveal the effect of unilateral decentralization on circardian rhythm of IOP in eyes of rats. Methods: Nine male Sprague-Dawley rats were exposed to a 12-hour light/dark cycle for 3 weeks. 24-hours IOP pattern was measured at six time points (8, 12, 16, 20, 24, and 4 circardian time) by Tonopen XL tonometer in awake state. After unilateral sympathectomy (cervical ganglionectomy), IOP measurements were performed at the same time points on post-operation 1, 2, 3, and 4 weeks. Results: 24-hour IOP pattern of rats showed a rhythmic pattern that appeared to be sinusoidal with 12-hour light/dark cycle. IOPs were low during the light phase and high during dark phase. After unilateral sympathectomy, the circardian rhythm of IOP was maintained in control eyes. But in sympathecotmized eyes, the circardian thythm of IOP was loss. Conclusions: These results show that sympathetic nervous systems contribute to the circardian rhythm of IOP in rats. J Korean Ophthalmol Soc 2008;49(11):1839-1844
류마티스관절염 환자에서 익상편수술 후 발생한 천공성 공막연화증
김재희 ( Jae Hee Kim ),김현옥 ( Hyun Ok Kim ),정용근 ( Yong Geun Jeong ),윤성은 ( Seong Un Yun ),이경주 ( Kyeong Ju Lee ),이창민 ( Chang Min Lee ),김완수 ( Wan Soo Kim ),송준경 ( Joon Kyung Song ),이상일 ( Sang Il Lee ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.1
The ocular manifestations of rheumatoid arthritis (RA) are common and they can vary from patient to patient. However, necrotizing anterior scleritis without inflammation (scleromalacia perforans) is a rare and serious opthalmic complication, and it is typically associated with long-standing RA. Although the etiology and pathogenesis of scleromalacia perforans are diverse and they are not completely understood, ophthalmic surgery is one of the well known causes of scleromalacia perforans. Patients with systemic autoimmune disease such as RA have an especially higher risk of scleromalacia perforans after opthalmic surgery. Because scleromalacia perforans is a potential threat not just to eyesight, but to life as well, early diagnosis and prompt treatment are required for its successful management. We experienced a case of scleromalacia perforans that developed after scleral excision of pterygium in a 58 year old woman who had a 7 year history of RA, and this was well treated with an early screral graft. We report here on this case along with a review of the relevant literature.