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간염 (肝炎) B 바이러스 DNA 혈중농도 (血中濃度)와 HBeAg / Anti - HBe 와의 상관 관계
송인성(In Sung Song),김정룡(Chung Yong Kim),이효석(Hyo Suk Lee),최상운(Sang Woon Choi),서정선(Jeong Sun Seo) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.4
N/A To evaluate the relationship between serum HBV DNA positivity and HBeAg/anti-Hbe status, and also the feasibility of HBeAg titer as an indirect parameter of serum HBV DNA level, 275 HBsAg- positive patients with acute and chronic liver disease were included in this study. The positive rate for serum HBV DNA in case of HBeAg positive/anti-HBe negative, HBeAg negative/anti-HBe negative, and HBeAg negative/anti-HBe positive was 92.5%, 63.3%, and 40.4%, respectively. Although the positive rate of HBV DNA in case of HBeAg positive/anti-HBe negativie was singificantly higher (p < 0.05) than the others, it was as high as about 50% (82/169) even in HBeAg negative cases regardless of anti-HBe positivity. The close correlation between log2 HBeAg titer and HBV DNA level in the serum was not demonstrable. We could, therfore, conclude that either detection of IIBeAg or measurement of HBeAg titer could not replace the determination of serum HBV DNA for the evaluation of infectivity of the HBsAg positive sera.
송인성 ( In Sung Song ),김선혁 ( Sun Hyuk Kim ),한상용 ( Sang Yong Han ),김정용 ( Chung Yong Kim ),박소배 ( So Bae Park ),전종민 ( Chong Min Jeon ) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1
N/A Fasting serum gastrin and secretin levels were measured by radioimmunoassay in 82 non- ulcer control subjects, 58 patients with active gastric ulcer, 83 patients with active duodenal ulcer, and 14 patients with active gastroduodenal ulcer. Fasting serum gastin and secretin levels were measured serially before and after treatment with Cimetidine and antacid(Amphojel) for 6 to 12 weeks. The results were as foIIows; 1) Patients with peptic ulcer had fasting Serum gastrin level similar to those observed in non-ulcer control subjects, but had higher fasting serum secretin level than non-ulcer control subjects. 2)No differences were found in fasting serum gastrin ar.d secretin level, in relation with ulcer site among patients with gastric ulcer. The fasting serum gastrin and secretin levels were also showed no differences in relation with age or presence of gastric erosion among patients with duodenal ulcer. 3) Fasting serum gastrin and secretin levels were not significantly altered before and after medication with cimetidine and antacid in patients with peptic ulcer. It is, therefore, suggested that gastric acidity did not directly correlated with fasting serum gastrin and secretin secretion.
유당흡수장애자 및 염증성 장질환 환자에서의 우유섭취량에 따른 유당흡수능과 유당불내성 증상의 발현양상
송인성(In Sung Song),정현채(Hyun Chae Jung),김정룡(Chung Yong Kim),문선희(Sun Hi Moon),황진혁(Jin Hyok Hwang) 대한내과학회 1999 대한내과학회지 Vol.56 No.5
N/A Objective : To define whether lactase-deficient subjects are intolerable to even a pack of milk(200ml) and whether milk intolerance in the patients with IBD is only due to lactose malabsorption, we performed this study. Methods : We evaluated 32 healthy adults and 12 patients with active stage of inflammatory bowel disease(IBD) who had not received antibiotics therapy within the previous 3 weeks. Thirty-two healthy adults underwent H2-breath test with 200, 400, 600 and 800ml of milk at 1st, 2nd, 3rd and 4th day of study, respectively. We measured their end-expiratory hydrogen concentrations and asked them to record the gastrointestinal symptoms. Twelve patients with IBD were tested only with 200ml of milk. Lactose malabsorption was defined as the increase of 20ppm over basal H2 concentration and lactose intolerance as having two or more of the following symptoms; abdominal pain, diarrhea, borborygmus and flatus. Results : The prevalence of lactase deficiency was 72%(23 of 32 subjects) at 800ml of milk(lactose 40g). Among the lactase-deficient subjects, lactose intolerance at 200ml of milk(lactose 10g) was noticed only in 13%(3 of 23 subjects). In the patients with active stage of IBD, the frequency of milk intolerance at 200ml of milk was 50%(6 of 12 subjects), which was higher than in the healthy adults(9%). But the prevalence of lactose malabsorber in the patients with IBD at 200ml of milk(17%) was not higher than in the healthy adults(16%). Conclusion : Most of lactase-deficient subjects(87%) can ingest one pack of milk without lactose intolerance. The increased prevalence of lactose intolerance in the patients with IBD at 200ml of milk is not originated from lactose malabsorption, but probably from incomplete colonic compensation salvage.
소화성 궤양 환자에서 Helicobacter pylori 의 약제 내성률과 재발현 및 재감염률을 고려한 H . pylori 박멸요법의 수립
송인성(In Sung Song),김나영(Na Young Kim),임채남(Chae Nam Lim),임선희(Sun Hee Lim),이계희(Kye Heui Lee),구명숙(Myung Sook Koo),정현채(Hyun Chae Jung),김정룡(Chung Yong Kim) 대한내과학회 1999 대한내과학회지 Vol.56 No.3
N/A Objective : This study was conducted to establish an ideal treatment regimen for H. pylori eradication in three aspects: clinical, microbiological, and reinfection. Methods : Four hundred thirty two patients with H. pylori positive peptic ulcer were randomized to receive two types of triple therapy: one includes colloidal bismuth subcitrate, metronidazole and tetracycline (BMT), and the other includes omeprazole, amoxicillin and clarithromycin (OAC). Results : More than 50% of symptom reduction within 1 week was 94.4% both in OAC and in BMT group. The percentages of side effects were 21.6% and 27.1% in OAC and BMT regimen, respectively. Good compliance with at least 85% intake was 99.0% and 95.2% in OAC and BMT regimen. The eradication rates of H. pylori were 85.9% and 89.1% in OAC and BMT regimen. Resistance rates to metronidazole and clarithromycin were 40.6% and 10.2% by E test, 74.3% and 27.0% by broth microdilution, and 45.3% and 10.9% by disk diffusion method. The eradication rates for H. pylori was 100% and 77.8% by BMT in patients with metronidazole-sensitive and -resistant strains, and 100% and 80.0% by OAC with clarithromycin- sensitive and -resistant strains, without significance by their resistances. The recrudescence rate within 1 year after eradication was 21.2% and 14.2% for OAC and BMT regimen without significant difference. The reinfection rate after 1 year was 4.0% and 5.0% for OAC and BMT regimen. Conclusion : Because the eradication rate of BMT regimen is 89.1% in spite of high metronidazole resistance rate, and there was no statistical difference in the aspects of symptom reduction, side effect, compliance, recrudescence and reinfection rate, BMT regimen is as favorable as OAC to eradicate H. pylori.
비전 시스템을 이용한 타공파이프 자동 절단장치 개발에 관한 연구
송인성(Song In-Sung),김학선(Kim Hack-Sun),정찬세(Jeong Chan-Se),김용석(Kim Yong-Suk),양순용(Yang Soon-Yong) 대한기계학회 2010 대한기계학회 춘추학술대회 Vol.2010 No.11
Punched pipe with exhaust noise is one of the very important parts. Production of punched pipes punching part, canaling part, cutting part will actually go through three processes. The first steel plate is required to punch a hole through the product through the pipe is welded to form canal. This produced a punched pipe about the pipe is approximately 6m. This product will be cut to fit the length of the cutting operation the operator is generally the length of pipe for each product will be cut by hand. This process occurs in large part to the tolerance and the precision of workers will vary depending on the skill to remove burrs after cutting its product through the process of completing a cycle time that is extending the production efficiency is degraded. In this paper, the exact length of punched pipe cut to Converted canal after Burr removal automatic method is described to have.
인간 리포코틴 - 1 유전자의 클로닝 및 대장균에서의 발현
허광래,박순희,강성만,송인성,이혜영,나도선 ( Kwahng Rae Huh,Soon Hee Park,Sung Man Kang,In Sung Song,Hay Young Lee,Doe Sun Na ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.4
A cDNA clone coding for lipocortin-1 was isolated from the cDNA library of human placental mRNA. Plasmid pHT1 was constructed by inserting the coding sequence into plasmid pKK233-2, a universal expression vector containing trc promoter. Lipocortin-1 was expressed constitutively or by induction with IPTG in E. colt strain C600 or JM109 harboring pHT1. The activity of purified lipocortin-1 was demonstrated by the in vitro phospholipase A₂ inhibitory activity.
한국인 간경섭증환자에서의 (肝硬燮症患者) 식도 (食道) 및 상부위장관내시경소견 (上部胃腸管內視鏡所見)
윤용범(Yong Bum Yoon),송인성(In Sung Song),최규완(Kyoo Wan Choi),박소배(So Bae Park),김선혁(Sun Hyuk Kim),전종민(Chong Min Jeon),김정룡(Chung Yong Kim),오인혁(In Hyuck Oh) 대한소화기학회 1982 대한소화기학회지 Vol.14 No.1
N/A Esophageal and gastroduodenal endoscopy was performed in 209 proven cirrhotic patients in order to demonstrate the frequency of the lesions found in upper gastrointestinal tract. The esophageal varix was demanstrated in 178 cases (85. 2%) among the 209 cirrhotics examined. The gastric erosion was found in 13 cases (6.2%), gastric mucosal homorrhasgic spots in 12 cases (5.7%) with peptic ulcer in 21 caes (10. 0%, gatric ulcer in 6.7%; duodenal ulcer in 3. 3%). There was no difference in the freguency of these lesions as the grade of esophageal varix increased.
김병관 ( Byeong Gwan Kim ),김유선 ( You Sun Kim ),김주성 ( Joo Sung Kim ),정현채 ( Hun Chae Jung ),송인성 ( In Sung Song ) 대한소화기학회 2002 대한소화기학회 춘계학술대회 Vol.2002 No.-
<목적> ASCA는 크론병에, 그리고 pANCA는 궤양성대장염에 비교적 특이한 자가항체로 알려져 있으나 아직 논란이 있는 실정이다. 본 연구에서는 크론병, 궤양성 대장염, 베체트 장염 그리고 장결핵환자와, 그 가족들을 대상으로 ASCA와 pANCA를 측정하여 진단적 유용성에 대하여 평가하고자 하였다. <방법> 1999년 1월부터 2000년 12월까지 서울대학교병원에서 치료를 받고 있는 크론병 85명, 궤양성 대장염 77명, 베체트 장염 36명, 장결핵