안저사진과 레트로모드로 촬영한 주사레이저검안경 영상의 드루젠 발견 비교

송인석,조희윤,이병로,In Seok Song,Hee Yoon Cho,Byung Ro Lee 대한안과학회 2011 대한안과학회지 Vol.52 No.10

Purpose: To compare SLO (scanning laser ophthalmoscope) retromode images with conventional color fundus photography for the detection of drusen. Methods: We obtained color fundus photography and SLO retromode images of the ten fellow eyes of ten patients with unilateral exudative age-related macular degeneration (AMD) and twenty eyes of 20 patients who had only drusen without exudative AMD. The numbers of druse in each image were compared within the same retinal boundary. Results: In the fellow eyes of unilateral exudative AMD, an average number of 63.1 ± 81.9 drusen in color fundus photography and an average number of 141.3 ± 124.1 drusen in SLO retromode images were detected (<em>p</em> = 0.005). In the eyes with only drusen, an average number of 57.0 ± 43.9 drusen in color fundus photography and an average number of 112.2 ± 82.0 drusen in SLO retromode images were detected (<em>p</em> = 0.000). In the presence of media opacity like cataract, drusen were better detected in SLO retromode images than they were in color fundus photography. Conclusions: About twice as many drusen were detected in SLO retromode images than in color fundus photography. Drusen were also better detected in SLO retromode images in cases of media opacity. SLO retromode images might provide more sensitive images for the detection of drusen than does color fundus photography. J Korean Ophthalmol Soc 2011;52(10):1189-1194

헤파린의 심막유착 방지효과에 관한 실험적 연구

송인석,이홍균,Song, In-Seok,Lee, Hong-Gyun 대한흉부심장혈관외과학회 1986 Journal of Chest Surgery (J Chest Surg) Vol.19 No.1

The pericardial adhesions following the first open heart surgery pose a major problem that can increase the morbidity and mortality in cases of reoperation because of the danger of damaging the heart, great vessels or grafts. The purpose of this study was to determine the effect of intrapericardial infusion of 5% dextrose solution and heparin on experimental pericardial adhesions. The 15 white rabbits were divided into three treatment groups of 5 animals each: group 1 [control group], group 2[5% dextrose group] and group 3 [heparin group]. At 4 weeks, all animals were sacrificed and the pericardial adhesions were graded as follows: 1[none], ll[mild], Ill[moderate] and IV[severe]. Histological examination was performed on a subset of each group. The difference of adhesion between control and heparin group was evaluated by Chi-square analysis. The results were as follows: 1. Pericardial adhesions developed in 80% of animals in group 1 and 2. 2. Only 40%> of animals in group 3 had mild to moderate pericardial adhesions. This was significantly different from the control group [P=0.01]. 3. Histological examination showed that the pericardium with adhesion was thickened with fibrosis, while that without adhesion was thin, normal appearance. 4. In group 3, there was no evidence of hemorrhage or hemorrhagic tendency in the pericardium.

기관지에 발생한 양성 점액상피종 1례 보

송인석,조건현,이홍균,Song, In-Seok,Jo, Geon-Hyeon,Lee, Hong-Gyun 대한흉부심장혈관외과학회 1984 Journal of Chest Surgery (J Chest Surg) Vol.17 No.4

Mucoepidermoid tumor arising from the bronchial tree as one of the bronchial adenoma is a extremely rare in incidence. And its clinical and histopathologic behavior has been reported as varying degree of benign to extremely malignant. Because symptoms are usually related to the bronchial obstruction or obstructive pneumonitis followed by endobronchial growth of tumor, frequently error is made in diagnosis of this tumor as entity of obstructive lung disease. We present a case of mucoepidermoid tumor with review of relevant literatures arising from the right middle lobe bronchus extending to intermediate bronchus in 47 years old housewife and was surgically removed by middle and lower Iobectomy.

연구.학술정보 효율적 검색을 위한 온톨로지 기반의 주제 색인어 구조화 방안 연구

송인석,Song, In-Seok 한국과학기술정보연구원 과학기술정보센터 2008 Journal of Information Science Theory and Practice Vol.39 No.4

본 연구에서는 정보검색도구 관점에서 지식조직체계로서 기존 시소러스 구축방안의 특성과 한계점을 검토하고, 대상 정보의 지식구조의 반영 및 정보 간의 의미관계 추론을 지원하는 온톨로지 기반의 주제 색인어 구조화 방안을 제시한다. 기존의 용어 중심의 시소러스와 달리, 단계별 연구프로세스 과정에서 수행되는 연구자의 정보행위 및 수요 분석에 때라 주제색인어의 개념을 식별 범주화하고, 인문사회과학 분야 학술논문의 지식체계를 구성하는 그 개념들 간의 유기적 관계정의를 통해 주제 색인어 집합의 의미구조를 정형화하였다. 이를 기반으로 각각의 온톨로지 기반 주제 색인어 집합은 구조화된 의미 색인으로서 대상 문서의 지식체계를 표현한다. 정보수요에 따라 정의된 공리나 추론규칙을 활용하여 이용자는 문제 해결에 적합한 정보를 대상 정보의 의미관계로 구성된 주제 도메인의 학술커뮤니케이션 네트워크상에서 분석적 정보탐색을 통해 효율적으로 검색 할 수 있다. In this paper, a ontology-based keyword structuring method is proposed to represent the knowledge structure of scholarly documents and to make inferences from the semantic relationships holding among them. The characteristics of thesaurus as a knowledge organization system(KOS) for subject heading is critically reviewed from the information retrieval point of view. The domain concepts are identified and classified by analysis of the information activities occurring in a general research process based on scholarly sensemaking model. The ontological structure of keyword set is defined in terms of the semantic relationship of the canonical concepts which constitute scholarly documents such as journal articles. As a result, each ontologically structured keyword set of a document represents the knowledge structure of the corresponding document as semantic index. By means of the axioms and inference rules defined for information needs, users can efficiently explore the scholarly communication network built on the semantic relationship among documents in an analytic way based on the scholarly sensemaking model in oder to efficiently retrieve the relevant information for problem solving.

프로스타그란딘(prostaglandin) 생합성효소

송인석,Song, In-Seok 한국통합생물학회 1997 한국동물학회 뉴스레터 Vol.14 No.1

국가과학기술종합정보서비스(NTIS)-기술.산업정보 서비스

송인석,Song, In-Seok 한국과학기술정보연구원 2008 지식정보인프라 Vol.30 No.-

고등학생의 비주장행동이 자살생각에 미치는 영향 :

은선경(Sun Kyoung Un),송인석(In Seok Song) 연세대학교 사회복지연구소 2014 한국사회복지조사연구 Vol.42 No.-

본 연구는 비주장행동이 자살생각에 미치는 영향을 알아보고, 이들의 관계에서 학교폭력피해경험의 매개효과와 폭력의식화의 조절효과를 알아보는데 그 목적이 있다. 연구의 대상은 서울시소재 고등학교 1-2학년 남․여 329명이며, 조사도구는 연구대상자의 일반적 특성, 비주장행동(독립변인), 학교폭력피해경험(매개변인), 자살생각(종속변인), 폭력의식화(조절변인) 등의 척도를 사용하였다. 폭력의식화 척도는 평균중심화에 의해 고·저 집단으로 구분하여 조절변인으로 분석되었다. 수집된 자료는 구조방정식모형(SEM)이용하여 매개효과, 잠재평균분석, 조절효과를 분석하였다. 연구결과는 다음과 같다. 첫째, 학교폭력피해경험이 비주장행동과 자살생각의 관계에서 매우 중요한 매개요인으로서 비주장행동이 높을수록 학교폭력피해경험이 증가하여 자살생각에 영향을 미치는 것으로 나타났다. 둘째, 비주장행동, 학교폭력피해경험, 자살생각 등의 수준에서 폭력의식화 수준이 높은 집단과 낮은 집단간에 유의한 차이가 발견되었다. 폭력의식화 수준이 낮은 고등학생들이 폭력의식화 수준이 높은 학생들보다 비주장행동, 학교폭력피해경험, 자살생각의 잠재평균이 더 높게 나타났다. 셋째, 비주장행동과 학교폭력피해경험의 경로에서, 그리고 학교폭력피해경험과 자살생각의 경로에서 폭력의식화 수준이 높은 집단과 낮은 집단 간의 조절효과가 있는 것으로 나타났다. 이는 폭력의식화 교육이 학교폭력피해와 자살생각을 감소시킬 수 있는 보호요인으로 작동할 수 있음을 보여준다. The purpose of this study was to research the influence of non-assertive behavior on the suicidal ideation and to investigate mediating effects of school violence experience and moderating effects of violence conscientization which are the desirable buffering mechanism as protection factor for students who experienced school violence in high school. The subjects of this study were 329 high school students in Seoul. The research tool is questionnaires which are consist of demographic characteristics of the subjects, school violence experience scale, analysis of non-assertiveness causes scale, violence conscientization scale, and suicidal ideation. In order to analyze the data of the study, multi-group analysis, latent mean analysis, moderated effect and mediated effect analysis were used. The major findings of this study were as following. First, there was a mediating effect on school violence experience between non-assertiveness behavior and suicidal ideation. Second, the mean value in non-assertiveness behavior, school violence experience, and suicidal ideation was higher in the group of low level violence conscientization than in the group of high level violence conscientization. Third, level of violence conscientization was moderated the pathway between non-assertiveness behavior and school violence experience and suicidal ideation on our model. Using these findings, social work practice, in particular, can be guided in terms of an important strategies for suicidal prevention program.

종합감기약 복용 후 발생한 양안 급성 폐쇄각발작 1예

홍은희(Eun Hee Hong),이민지(Min Jee Lee),송인석(In Seok Song) 대한안과학회 2016 대한안과학회지 Vol.57 No.2

목적: 종합감기약(성분: Chlorpheniramine maleate, phenylephrine hydrochloride, belladonna alkaloid) 복용 후 발생한 양안의 급성폐쇄각발작 1예를 경험하여 보고하고자 한다. 증례요약: 67세 남자 환자가 내원 1일 전부터 시작된 양측성 두통, 구토와 동반된 양안 통증 및 시력저하를 주소로 내원하였다. 환자는 내원 3일 전부터 하루 3회 일반의약품의 종합감기약을 복용하고 있었다. 최대교정시력 우안 0.3, 좌안 0.7이었고, 안압은 우안 50mmHg, 좌안 40 mmHg, 굴절값은 우안 +0.75 D sph=-0.75 D cyl×100, 좌안 +1.25 D sph=-1.25 D cyl×80으로 측정되었다. 양안의 중심 전방깊이는 중심 각막두께의 3배, 주변부 전방깊이는 1/4 이하였고, 전방각경 검사상 양안의 전방각은 폐쇄되어 있었다. 감기약을 끊고 축동제 및 안압하강제 투여 후 증상은 호전되었다. 10일 후 양안에 레이저 주변부홍채절개술을 시행하였고 4개월 후까지 증상의 재발이나 안압의 상승은 관찰되지 않았다. 결론: 시중에서 쉽게 구할 수 있는 종합감기약에 의해서도 급성 폐쇄각발작이 발생할 수 있으므로 급성 폐쇄각발작의 소인이 있는 환자에서는 이러한 감기약 복용 시에 주의가 필요할 것이다. Purpose: The authors report a case of bilateral simultaneous acute angle closure attack following administration of an over-the-counter common cold medication (ingredients: chlorpheniramine maleate, phenylephrine hydrochloride, and belladonna alkaloid). Case summary: A 67-year-old man visited the emergency room with a sudden onset of bilateral blurred vision and ocular pain accompanied by headache, nausea, and vomiting. He had taken an over-the-counter common cold medication three times per day for three days before the visit. His visual acuity was 0.3 and 0.7 and intraocular pressure (IOP) was 50 mm Hg and 40 mm Hg in right and left eye, respectively. The refraction in manifest refractive test was +0.75 D sph = ‑0.75 D cyl × 100 in right eye and +1.25 D sph = ‑1.25 D cyl × 80 in left eye. The anterior chamber depth was three times the corneal thickness in center and less than 1/4 of the corneal thickness in periphery in both eyes on van Herick method. The angles of both eyes were closed on gonioscopy. He was treated with ocular hypotensive medication and miotics followed by withdrawal of common cold medications. After 10 days, bilateral neodymium-doped yttrium aluminium garnet (Nd:YAG) laser peripheral iridotomies were done. During four months of follow-up, there was no recurrence of angle closure attack, and normal IOP was maintained without glaucoma medications. Conclusions: Common cold medications which are easily accessible can induce acute angle closure attack in those who are predisposed to develop angle closure attacks, hence attention must be taken in those people when taking common cold medications

매체혼탁에 따른 파장가변 빛간섭단층촬영과 스펙트럼영역 빛간섭단층촬영 영상의 질 비교

홍은희(Eun Hee Hong),박승훈(Seung Hun Park),이정욱(Jung Wook Lee),이주향(Ju Hyang Lee),송인석(In Seok Song),이병로(Byung Ro Lee) 대한안과학회 2016 대한안과학회지 Vol.57 No.2

목적: 안구 매체혼탁이 있는 안에서 파장가변 빛간섭단층촬영(swept-source optical coherence tomography, SS-OCT)과 스펙트럼영역 빛간섭단층촬영(spectral domain optical coherence tomography, SD-OCT) 영상의 질을 비교하고자 하였다. 대상과 방법: 정상 40안, 매체혼탁 60안(백내장 30안, 유리체혼탁 20안, 각막혼탁 10안)에서 SS-OCT와 SD-OCT의 6×6 macularscan을 시행하였다. 각 영상에 대해 영상의 질의 객관적 지표로 quality factor (QF)를, 주관적 지표로 subjective grading scale(SGS)을 측정하여 정상안과 매체혼탁안에서의 영상의 질 차이를 비교하고 매체혼탁의 종류와 정도에 따른 영상의 질 차이를 비교하였다. 결과: 정상안과 매체혼탁안 모두에서 SD-OCT에 비해 SS-OCT에서 객관적 지표, 주관적 지표 모두 더 높은 영상의 질을 보였다(p<0.001). SS-OCT와 SD-OCT의 영상의 질 차이는 매체혼탁의 종류에 따른 유의한 차이는 없었고(QF: p=0.188, SGS: p=0.635), SD-OCT QF를 기준으로 매체혼탁의 정도에 따라 분류한 두 군(Group I: 20≤QF<50, II: 0≤QF<20) 간의 비교에서도 유의한 차이는 보이지 않았다(QF: p=0.088, SGS: p=0.051). 결론: SS-OCT는 매체혼탁의 종류나 정도에 관계없이 SD-OCT에 비해 개선된 영상의 질을 보여주며, 이는 매체혼탁안에서 정확한 질병 진단 및 경과 평가에 도움이 될 것으로 여겨진다. Purpose: To compare the image quality between swept-source optical coherence tomography (SS-OCT) and spectral domain optical coherence tomography (SD-OCT), especially in eyes with media opacity. Methods: Forty eyes without media opacity and 60 eyes with media opacity (30 eyes with cataract, 20 eyes with vitreous opacity, and 10 eyes with corneal opacity) were included in this study. SD-OCT and SS-OCT 6 × 6 macular scans were taken by a single operator. For image quality analysis, a total of 200 OCT images were subjectively graded by two trained retina specialists and measured quantitatively using the image quality factor (QF) built into the OCT devices. Results: Compared to conventional SD-OCT, SS-OCT had statistically significantly better subjective and objective grades in the normal group, as well as each of the media opacity groups (p-value < 0.001). In both the subjective and objective grades, there was no significant difference according to the types of media opacity (QF: p = 0.188, subject grading scale [SGS]: p = 0.635) and the degree of media opacity (Group I: 20 ≤ QF < 50, Group II: 0 ≤ QF < 20; QF: p = 0.088, SGS: p = 0.051) in the superiority of image quality of SS-OCT to SD-OCT. Conclusions: In this media opacity patient population, swept-source OCT is a superior diagnostic tool when compared with SD-OCT in both objective and subjective assessments, even in the ocular media opacity. This result may be useful in diagnosis and progression detection of retinal disease in media opacity eyes.

Hybrid Type IPMSM 적용을 통한 Spindle Machine의 토크 리플 저감 설계

송인석(In-Seok Song),장도현(DoHyun Jang),황영호(Young-Ho Hwang),서채원(Chae Won Seo),정상용(Sang-Yong Jung) 대한전기학회 2023 대한전기학회 학술대회 논문집 Vol.2023 No.7