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안인성,손현석,Ahn, In-Sung,Son, Hyeon-S. 대한예방의학회 2007 예방의학회지 Vol.40 No.2
Objectives : Since the first human infection from avian influenza was reported in Hong Kong in 1997, many Asian countries have confirmed outbreaks of highly pathogenic H5N1 avian influenza viruses. In addition to Asian countries, the EU authorities also held an urgent meeting in February 2006 at which it was agreed that Europe could also become the next target for H5N1 avian influenza in the near future. In this paper, we provide the general and applicable information on the avian influenza in the bioinformatics field to assist future studies in preventive medicine. Methods : We introduced some up-to-date analytical tools in bioinformatics research, and discussed the current trends of avian influenza outbreaks. Among the bioinformatics methods, we focused our interests on two topics: pattern analysis using the secondary database of avian influenza, and structural analysis using the molecular dynamics simulations in vaccine design. Results : Use of the public genome databases available in the bioinformatics field enabled intensive analysis of the genetic patterns. Moreover, molecular dynamic simulations have also undergone remarkable development on the basis of the high performance supercomputing infrastructure these days. Conclusions : The bioinformatics techniques we introduced in this study may be useful in preventive medicine, especially in vaccine and drug discovery.
배세은(Bae, Se-Eun),김하연(Kim, Ha-Yeon),손현석(Son, Hyeon-S.),이현실(Rhee, Hyun-SiIl) 한국산학기술학회 2011 한국산학기술학회논문지 Vol.12 No.4
성인병관리 및 개인건강관리를 위해 개인건강기록(PHR)은 매우 중요하다. 현재 노인 또는 장년층과 미래 노인, 장년층과의 차이를 비교해 보기 위해 젊은층(대학생)과 성인을 대상으로 조사하였다. 방법: 두 연령집단의 면대면 설문조사를 성인(131명)과 대학생(398명)을 2009년 5월 11일부터 22일까지 실시하였다. 설문지는 18개 문항으 로 구성되었다. 결과 및 결론: 젊은층보다는 성인층에서 PHR을 사용하겠다는 의지(대학생그룹3.3, 성인그룹3.7)와 지 인들에게 PHR을 추천하겠다는 의지(대학생그룹3.1, 성인그룹3.8)가 비교적 높게 나타났다. 반면, 성인그룹은 종이형 PHR(63.2%)을 선호하였으며 대학생그룹은 ePHR(71.1%)을 더 선호하였고, PHR에 담겨져 있는 정보유출에 대한 우려 가 성인그룹(3.7)보다 대학생그룹(4.5)이 높은 것으로 나타났다. PHR에 대한 교육 시기는 고등학교와 대학교로 응답하 였다. 따라서 젊은층의 PHR활성화를 위해서는 ePHR에 대한 조기교육과 사용이 편리한 PHR개발이 이루어져야 할 것 으로 사료된다. Objectives: Using a PHR(Personal Health Record) is very important for the management of chronic disease and health. The young age group in this study was asked to pretend that they were members in the old age group (adult group here after) in order to investigate the recognition level differences in such conditions. Methods: We conducted face to face surveys with two age groups. 131 Adults and 398 University students, from May 11 to 22 in 2009. The questionnaires were composed of 18 items. Results & Conclusion: Adults replied more favorably than University students in using PHR willingness(University group 3.3score, Adults 3.7score) and recommendation(university 3.1score, Adults 3.8score). Adults liked paper PHR (63.2%), whereas, University students favored electronic Personal Health Record (71.1%). University students were highly concerned about disclosing the information(4.5score) of their PHR. They thought the appropriate time of education for PHR is high school or University degree. Therefore, in the future, it is vital that a PHR for young age group should be begun in early education and that an ePHR should be developed.