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신제품 공개가 전략적 제휴를 맺은 기업의 주가에 미치는 영향
손인성(In-Sung Son),김진수(Jin-Su Kim) 한국인터넷전자상거래학회 2016 인터넷전자상거래연구 Vol.16 No.6
This paper studies the stock prices of the suppliers concluded strategic alliances with Samsung which preannounced new product(Galaxy S) from 2010 to 2016 through an event study. To do it, we estimate abnormal returns regarding companies listed on capital market in order to examine different market reaction. The results are follows: Preannouncement of Galaxy S had positive effect on stock price of all suppliers one day before preannouncement. Divided total samples into 2 groups(one is existing partner and another is new partner), it also had positive effect on stock price of both partners. Just new partners have more significant than existing. This study is meaningful in presenting new points in terms of strategic alliances through empirical analysis concerning enterprise value of strategic alliances with Samsung according to the preannouncement.
면역억제 치료 후 Darbapoetin에 반응한 진성 적혈구 무형성증
손인성 ( In Sung Son ),김도영 ( Do Young Kim ),박수연 ( Soo Youn Park ),나하영 ( Ha Young Na ),이정현 ( Jung Hyun Lee ),허태회 ( Tae Hwe Heo ),조영일 ( Young Il Jo ) 대한내과학회 2013 대한내과학회지 Vol.84 No.5
항 EPO 항체에 의한 PRCA는 매우 드물지만 적절한 치료를 하지 않으면 지속적인 적혈구 수혈이 필요하게 되므로 문제가 된다. PRCA가 진단되면 ESA 투여를 중단하고 면역억제 치료를 하는 것이 필요하다. 특히 항 EPO 항체는 모든 종류의 ESA 제제와 교차반응을 하므로, 어떤 ESA 제제로도 교체 투여하지 않아야 한다. 국내에서는 3예의 증례가 보고되었는데, 면역억제 치료를 시행하였으나 모든 예에서 치료에 성공하지 못하였다. 저자들은 EPO-α를 피하 주사하던 환자에서 발생한 PRCA를 면역억제 치료 후에 darbepoetin-α로 교체 투여하여 성공적으로 치료한 예를 경험하였기에 문헌고찰과 함께 보고한다. Patients with erythropoiesis-stimulating agent (ESA)-induced pure red cell aplasia (PRCA) should not routinely be switched to an alternative ESA or to darbepoetin-α because anti-erythropoietin (anti-EPO) antibodies cross-react with all kinds of recombinant ESAs. We present a case of ESA-induced PRCA in a 69-year-old man on hemodialysis whose anemia improved with reintroduction of darbepoetin-α following immunosuppressive therapy. The patient developed severe anemia after 15 months of subcutaneous administration of erythropoietin-α. After the diagnosis of PRCA, erythropoietin-α was discontinued and immunosuppressive therapy with a combination of prednisolone and oral cyclophosphamide was initiated. After 4 months of immunosuppressive therapy, the anti-EPO antibody titer was markedly decreased; however, esophageal candidiasis developed. Additional therapy with cyclosporine alone instead of prednisone and cyclophosphamide was performed, and anti-EPO antibody was subsequently not detected. Darbepoetin-α was then reintroduced, and the patient`s anemia improved without red cell transfusion. In conclusion, ESA-induced PRCA was successfully treated with reintroduction of darbepoetin-α following immunosuppressive therapy. (Korean J Med 2013; 84:742-746)
손인성(Son, In-Sung),김동현(Kim, Dong-Hyun),김한수(Kim, Han-Soo),심재현(Shim, Jae-Hyun) 대한건축학회 2014 대한건축학회논문집 Vol.30 No.12
The objective of this research is to investigate and analyze the current status of the tower observatory developments based on their background information both in business and architectural aspects. Actual twenty three case-study sites are visited, and data collections are conducted in the preparatory stage. The papers and research materials are scarce on this subject, and preceding studies and specific architectural guidelines are found insufficiently researched. Brief descriptions of the result are following. First, most tower observatories are operated by public finance of local government. Commonly, the profits are generated by subsidiary facilities like exhibition spaces and public relations facilities. Second, the majority of average height is around 40 to 120m, relatively low in height in steel-concrete structure. The internal space layout is generally laid out on two-floor type in circular perimeter shape. From the chronological comparison study, there is a certain shift in the development from the private sector to the public one along with varying shapes and sizes.
손인성(Son, In Sung),김진수(Kim, Jin Su) 한국국제회계학회 2013 국제회계연구 Vol.0 No.48
본 연구는 회사채 발행능력인 기업의 부채수용력(Debt Capacity)을 이용하여 자본조달순서이론(Pecking Order Theory)을 검정하였다. 2000년부터 2010년까지 한국 유가증권시장 및 코스닥시장 상장기업을 대상으로 실증 분석한 결과는 다음과 같다. 대부분의 한국 유가증권시장 상장기업, 대기업, 수도권 기업은 부채수용력에 제한이 없어 부채발행을 통해 자금부족분을 충당한다. 반면에 코스닥시장 상장기업, 중소기업, 비수도권 기업은 부채수용력의 제약으로 주식발행을 통해서 자금을 조달하고 있음을 확인하였다. 정보비대칭 하에서 역선택비용이 매우 높은 소규모 고성장 기업의 경우 자본조달순서이론이 지지되지 않는 기존 연구 결과에 대해 부채수용력을 이용함으로써 그 설명력이 향상됨을 알 수 있었다. This paper empirically examines the pecking order theory with the measure of debt capacity of Korean firms. This study sample consists of firms listed on the Korea Securities Market and KOSDAQ Market from 2001 to 2010. The main results are as follows. Due to their lack of debt capacity constraints, most of the firms listed on Korea Securities Market, major firms and the capital area firms cover the financial deficit through issuing debt. On the other hand, the KOSDAQ listed firms, small businesses and non-capital area firms was confirmed to issue shares with debt capacity constraints. Under asymmetric information, adverse selection cost of the small high-growth firms is too high. So the results of previous studies suggest that they don"t follow the pecking order theory. However, by using a debt capacity, its explanatory power could be improved.
손인성,윤순민,김학신,육영호,박병황,김주현,Son, In-Sung,Yoon, Soon-Min,Kim, Hak-Sin,Yuk, Young-Ho,Park, ByeongHwang,Kim, JuHyun 한국군사과학기술학회 2014 한국군사과학기술학회지 Vol.17 No.2
In terms of chemical detection performance related with chemical material sampling, this investigation shows optimized values, resulted from minimizing loss from air turbulence and other reasons when pressure changes on the basis of sampling flow rate Based on simulations and pressure control of the outside conditions it became possible to obtain ion mobility detection optimum values, and to derive standard pressure conditions that is appropriate for DMS characteristic.
새로운 플라보노이드 유도체인 DA-6034의 TNBS 유발성 염증성대장염 모델에서의 치료효과
손미원(Mi Won Son),고준일(Jun Il Ko),김희기(Hee Kee kim),장동경(Dong Kyung Jang),유무희(Moo Hi You),김원배(Won Bae Kim),이강춘(Kang Chun Lee),송인성(In Sung Song) 대한약학회 1998 약학회지 Vol.42 No.2
The efficacy of DA-6034, a new flavonoid derivative, was investigated in comparison with sulfasalazine in a trinitrobenzene sulfonic acid (TNBS)-induced rat colitis. Under light anaesthesia with ether, rats were subjected to intracolonic administration of 30mg TNBS in 50% ethanol (0.5ml) and were then sacrificed at 7 or 21 days after colitis induction. The TNBS control group (the saline treated colitic rat) exhibited ulceration and inflammation of the distal colon with formation of granuloma and pathologic connections. Moreover, an increase in colonic myeloperoxidase (MPO) activity (investigated as an index of leukocyte adhesion and accumulation) and an elevated colonic leukotriene B4 (LTB4) level were observed. The colitic rats received DA6034 (0.3-30mg/kg) or sulfasalazine (50-100mg/kg), prednisolone (0.3-3mg/kg) after the induction of colitis until they were sacrificed. Oral treatment with DA-6034 resulted in significant reductions of macroscopic colonic damage, colonic inflammation. DA6034 had a more potent effect than sulfasalazine and prednisolone on macroscopic colonic damage, while it has similar effect with prednisolone on the reduction of colonic LTB4 synthesis and MPO activity. This study show, therefore, that DA-6034 is effective m attenuating the colonic lesion in an TNBS-induced colitis model. Furthermore, the results suggest that the effect of DA-6034 is partially related to its action on LTB4 synthesis and MPO inhibition.
황용 ( Yong Hwang ),이상헌 ( Sang Heon Lee ),홍성철 ( Sung Chul Hong ),김도영 ( Do Young Kim ),김용진 ( Yong Jin Kim ),서정웅 ( Jung Woong Seo ),손인성 ( In Sung Son ),정현아 ( Hyun A Jung ),최홍석 ( Hong Seok Choi ),이정화 ( Jun 대한류마티스학회 2012 대한류마티스학회지 Vol.19 No.4
Giant cell arteritis (GCA), the most common form of systemic vasculitis in adults, preferentially involves large and medium-sized arteries in patients over the age of 50. The classic manifestations are headaches, jaw claudication, polymyalgia rheumatica, and visual symptoms. Acute myeloid leukemia (AML) is a hematopoietic stem cell disorder characterized by a block in the differentiation of hematopoiesis, resulting in the growth of a clonal population of neoplastic cells or blasts. This malignant alteration in hematopoietic stem cells leads to a loss of normal hematopoietic function, which, if left untreated, typically leads to death within weeks to months of its clinical presentation. Although there have been reports of CLL or CML accompanied by several kinds of autoimmune vascular diseases, such as polymyalgia rheumatica, GCA, or necrotizing temporal arteritis, no studies have reported a case of AML with GCA. We experienced an 80-year-old male patient who developed AML 6 years after the diagnosis of GCA. He was under the use of oral glucocorticoid, hydroxychloroquine, and methotrexate at the time of the diagnosis of the AML. This is the first case in Korea to report GCA accompanied by AML.