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이관호 ( Kwan Ho Lee ),김형욱 ( Hyung Ook Kim ),류창학 ( Chang Hak Yoo ),손병호 ( Byung Ho Son ),박용래 ( Yong Lai Park ),조용균 ( Yong Kyun Cho ),김흥대 ( Hung Dai Kim ),한원곤 ( Won Kon Han ) 대한소화기학회 2012 대한소화기학회지 Vol.59 No.3
Background/Aims: Radiofrequency ablation (RFA) has been mostly used as a therapeutic alternative to hepatic resection for treating liver metastasis of colorectal cancer. The purpose of the present study was to determine whether there were differences in outcome between RFA and surgical resection in the treatment of colorectal cancer with liver metastases. Methods: We performed a retrospective analysis of 53 patients who underwent only hepatic resection or only RFA for colorectal liver metastases. Twenty-five patients who underwent hepatic resection were compared with 28 patients who underwent RFA for synchronous or metachronous liver metastases. Results: The median CEA level at the time of diagnosis of liver metastases was significantly higher in the resection group (14.2ng/mL vs. 2.8ng/mL, p=0.002). The median size of main liver metastases was significantly larger in the resection group (4.0 cm vs. 2.05 cm, p=0.002). There was no difference in the percentage of patients experiencing major complication (one patient in each group). The marginal recurrence rate was significantly higher in the RFA group (p=0.004). Disease-free and overall survival were longer in the resection group (p=0.008 and 0.017, respectively). In multivariate analysis, only the type of treatment was a factor associated with disease-free and overall survival (p=0.004 and 0.007, respectively). Conclusions: Because of the high marginal recurrence rate, RFA shows an inferior outcome in comparison with surgical resection. Therefore, RFA should be considered for only selected patients with unresectable (by any means) disease or with high operative risk.
볼록 검안렌즈의 MTF 성능 분석 및 이론적 해석에 대한 연구
방현진,이종웅,손병호,안교훈,최은정,Bang, Hyun Jin,Lee, Jong Ung,Son, Byung Ho,Ahn, Kyo Hoon,Choi, Eun Jung 한국광학회 2013 한국광학회지 Vol.24 No.5
10 diopter에서 20 diopter까지의 양볼록 검안렌즈에 대한 백색광 MTF(Modulation Transter Function)를 각주파수와 시력으로 나타낸 후, 이들을 각각 AIM(Aerial Image Modulation) curve와 비교하였다. 축상시야에서 평가된 양볼록 검안렌즈 모두 시력 2.0까지는 란돌트 링을 분해할 수 있는 MTF를 가지고 있었다. 하지만 반시야각 $5.0^{\circ}$인 비축시야에서는 10 diopter의 검안렌즈는 시력 0.9, 20 diopter의 검안렌즈는 0.8까지 란돌트 링을 분해할 수 있는 것으로 평가되어 시력을 1.0까지 측정하기에는 충분한 해상력을 가지지 못한 것으로 평가되었다. White light MTF(Modulation Transter Function)s of biconvex trial lenses from 10 to 20 diopter (D) were represented as a function of angular frequency and visual acuity, and then they were compared with AIM(Aerial Image Modulation) curves. All of the biconvex trial lenses evaluated in on-axis mode had MTF performance that could resolve Landolt's ring up to visual acuity 2.0. However, in a half field angle of five degrees, the trial lens of 10 diopters was able to resolve Landolt's ring up to visual acuity 0.9, and that of 20 diopter only up to visual acuity 0.8. This means that the trial lenses in the case of a half field angle of five degrees do not have sufficient resolution to measure visual acuity by 1.0.