중복 Z-성형술을 이용한 큐피드활의 교정

유선열,서일영,Ryu, Sun-Youl,Seo, Il-Young 대한악안면성형재건외과학회 2005 Maxillofacial Plastic Reconstructive Surgery Vol.27 No.1

이차 구순비성형술을 받고자 본과에 내원한 편측성 완전 구순구개열을 가진 29세 남자 환자에서 상방으로 반전된 큐피드활과 적순부의 휘파람 변형을 교정하기 위해 중복 Z-성형술을 시행하였다. 수술 후에 반전된 큐피드활이 정상적인 형태로 재건되고 휘파람 변형이 없어졌으며 상순의 긴장도가 완화되었다. 중복 Z-성형술시 적순부 내에서만 피판을 형성하므로 피부에는 새로운 반흔이 생기지 않아 심미적으로 만족스러웠고 상순결절은 더욱 볼록해 졌다. 수술 4년경과 후 큐피드활은 부드러운 곡선으로 좌우 대칭을 이루고 매우 자연스럽게 보였으며 장기적인 추적관찰 결과 양호한 결과를 보였다. 중복 Z-성형술은 반전된 큐피드활의 교정시 다른 수술방법에 비해 술식이 간단하고 주위조직 손상이 적으며 휘파람 변형의 교정도 가능한 좋은 방법이라고 사료된다. Cupid's bow, upper lip, columella, and ala of nose are esthetically important, in which their symmetrical plasties determine success or failure of the surgery in cleft lip and palate patients. Z-palsty and its modifications are simple and effective. The double Z-plasty is economical in surgical time and esthetics in reconstructing the cupid's bow compared with other methods. We report a 29-year-old male patient who represented reversed cupid's bow and whistle deformity after the primary repair of the cleft lip. He was corrected the cupid's bow using a double Z-plasty. The reversed cupid's bow was corrected to a normal shape and the whistle deformity disappeared. The tightness of the upper lip was relieved after the operation. The double Z-plasty was esthetically successful because the procedure was limited in the vermilion and did not produce a new scar on the skin. Furthermore, the lip tubercle became protuberant. The cupid's bow was symmetrically smoothly curved at 4 years after the operation. These results indicate that the double Z-plasty is simple, less traumatic to the surrounding tissues, and suitable for the correction of whistle deformity.

Tricalciumaluminate의 초기 수화반응에 미치는 $K_2O$의 영향

한기성,최만,서일영,Han, Ki-Sung,Choi, Man,Seo, Il-Young 한국세라믹학회 1982 한국세라믹학회지 Vol.19 No.2

Two kinds of clinker liquid melts, one containing 2.0% of $K_2O$ and the other without $K_2O$, were prepared with the similar composition as those developed during the firing of portland cement clinker. One portion of melt was quenched and found to consist of glass together with traces of proto-$C_3A$, and the other portion was allowed to cool spontaneously to crystallize $C_3A$ and calciumferrite well. The product obtained by crystallization of the melt without $K_2O$showed cubic $C_3A$, while orthorhombic $C_3A$ was formed from the crystallized product containing $K_2O$. Studies on the hydration behavior of the samples made from the melts with 30% of gypsum were carried out for 24 hours by observation at regular intervals ettringite, monosulphate hydrates and gypsum which were formed or consumed during hydration. The samples without $K_2O$ in the melts were hydrated wth addition of proper amount of $K_2SO_4$ in the water for hydration. Hydration behavior of glassified $C_3A$ showed that it has low reactivity relative to crystallized $C_3A$, and also hydration reactivity of orthorhombic $C_3A$ was much lower than that of cubic $C_3A$ in 60 minutes. Potassium sulphate in the solution reduced the hydration reactivity of $C_3A$ . Evolution peaks of hydration heat examined by twin-type conduction micro-calorimeter showed that glassified $C_3A$ without $K_2O$ had secondary peak after 9 hours and $C_3A$ containing $K_2O$ after 12 hours. When crystallized $C_3A$ was hydrated, initial peaks of hydration heat were considerably high and there was no secondary peak for cubic $C_3A$ but the secondary peak of orthorhombic $C_3A$ appeared after 4 hours.

Treacher Collins 증후군 환아에서 급성 기도 폐색

유선열(Sun-Youl Ryu),서일영(Il-Young Seo),황웅(Ung Hwang),김선국(Sun-Kook Kim) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.5

Treacher Collins syndrome is inherited as an autosomal dominant trait with variable penetrance. It shows a marked variability even in the same family. This syndrome is developmental defect affecting the branchial arches. It is not usually associated with acute respiratory distress, but has symptoms of microtia, hypoplastic zygomatic bones, hypoplastic mandibular rami, and bilateral coloboma. It usually requires an emergency operation immediately after the birth. We experienced an infant with Treacher Collins syndrome who showed retrognathia, glossoptosis, microtia, and cleft palate. Intermittent cyanosis, depression of the chest, respiratory difficulty associated with airway obstruction, and swallowing difficulty were also observed. To relieve severe upper airway obstruction caused by retrognathia and glossoptosis, we simultaneously performed tongue-lip adhesion and subperiosteal release of the floor of the mouth. The respiratory and swallowing difficulties were relieved and the tongue repositioned anteriorly. We report the present case with a review of the literature.

두개 파상풍의 치험례

류승희(Seung-Hee Ryu),서일영(Il-Young Seo),박홍주(Hong-Ju Park),오희균(Hee-Kyun Oh) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.4

Cephalic tetanus is a rare subtype of tetanus in which trismus is a charateristic symptom. The paralysis of one or more cranial nerves can occur. The 7th cranial nerve is most frequently involved. It account for 1 to 3% of the tetanus and has a mortality of 15 to 30%. The incubation period is 1 to 14 days, and approximately two thirds of tetanus cases progress to generalized tetanus. Generally, the symptoms of cephalic tetanus can include : facial pain, trismus, dysphagia, muscle twitching spasms of the face and jaw (risus sardonicus), neck stiffness and malaise. We present a case of cephalic tetanus who 54-year male patient had trismus and dysphagia. There was no history of trauma. As there was a delay in diagnosis of cephalic tetanus, respiratory disorder and intermittent general spasm occurred. The patient was treated by injection of antibiotics, muscle relaxant, and human anti-tetanus immunoglobulin. His symptoms were disappeared, and he was discharged ambulatory.

악골에 발생한 법랑아세포종의 임상적 연구

김현섭(Hyun-Syeob Kim),류재영(Jae-Young Ryu),유민기(Min-Gi Yu),서일영(Il-Young Seo),Uttom Kumar Shet,국민석(Min-Suk Kook),박홍주(Hong-Ju Park),유선열(Sun-Youl Ryu),최홍란(Hong-Ran Choi),오희균(Hee-Kyun Oh) 대한구강악안면외과학회 2007 대한구강악안면외과학회지 Vol.33 No.5

Ameloblastoma, a benign tumor of odontogenic type, represents 10% of all tumors of the jaw. It is localized in the mandible (80%) and in the maxilla(20%). In every case, the selection of the surgical treatment must consider some fundamental elements, including the age and general state of health the clinicopathological variant, and the localization and extent of the tumor. This study was invested the clinicopathological findings of 23 patients with ameloblastoma which had been diagnosed by biopsy during the period of 1987 to 2005 at Chonnam National University Hospital. And it contained the statistical analysis according to the treatment methods and the clinicopathological findings such as sex, age, location, chief complaints, duration, radiographic findings, histologic findings, treatment methods. The results obtained are were follows. The age of patient ranged from 10 to 91 years(means, 35.9 years) at biopsy. Thirteen(57%) of the 23 subjects were males, and 10(43%) were females. Twenty(87%) of the 23 ameloblastomas were located in the mandible. Swelling was the most common symptom and was experienced by 20(87%) patients. Radiographically, 11(48%) of the 23 tumors were unilocular with a well-demarcated border and 12(52%) were multilocular. The most common histologic pattern was plexiform and acanthomatous rather then follicular. Conservative treatment was performed 7 cases(30%), radical treatment 11 cases(48%), and combined treatment 5 cases(22%). Follow-up period ranged from 2.1 years to 22 years(mean 5.1 years). Based on the above results, surgical excision after marsupialization was found to be useful as a preliminary treatment of the large cystic ameloblastoma in children and adolescents. On the contrary, the lesion with a soap bubble appearance, the one with ineffective marsupialization was subjected to extensive excision of the tumor with a wide margin of normal bone.

Pierre Robin sequence 환자에서 기도 폐색의 외과적 치료

유선열(Sun-Youl Ryu),이용욱(Young-Uk Lee),서일영(Il-Young Seo) 대한구강악안면외과학회 2004 대한구강악안면외과학회지 Vol.30 No.3

The deformities of micrognathia and glossoptosis in the newborn are frequently associated with a cleft palate, which is known as Pierre Robin sequence. Upper airway obstruction is the most serious problem in these patients. Treatment of Pierre Robin sequence includes either positional or surgical intervention. Mild cases are often managed in the prone position. However, when the patient fails to thrive due to chronic upper airway obstruction, or severe respiratory distress ensures despite positional treatment, surgical intervention is mandatory to relieve the obstruction. We experienced three infants with Pierre Robin sequence who showed a symptom triad of micrognathia, glossoptosis, and cleft palate. Intermittent cyanosis, depression of the chest, respiratory difficulty and feeding problems were also observed. To relieve severe upper airway obstruction caused by micrognathia and glossoptosis, we simultaneously performed modified tongue lip adhesion (TLA) and a subperiosteal release of the floor of the mouth (SRFM). Respiratory and feeding difficulties were relieved, the tongue positioned anteriorly, body weight increased, and mandibular growth improved. Simultaneous TLA and SRFM may constitute a simple and reliable method for surgical treatment of airway obstruction in patients with Pierre Robin sequence.

구순접합술이 회전신전법에 의한 편측성 완전 구순열 수복에 미치는 영향

유선열(Sun-Youl Ryu),박충열(Chung-Youl Park),서일영(Il-Young Seo) 대한구강악안면외과학회 2003 대한구강악안면외과학회지 Vol.29 No.5

The present study was carried out to evaluate the postoperative results of Millard rotation-advancement repair (MR) and lip adhesion followed by Millard rotation-advancement repair (LAMR) in unilateral complete cleft lip. Twenty patients with unilateral complete cleft lip underwent MR or LAMR at the Department of Oral and Maxillofacial Surgery of Chonnam University Hospital over a period of 6 years (January 1994 to December 1999) were analyzed. The surgical results following the operation were assessed on the basis of scoring, vertical lip length, and scar hypertrophy. The mean score was better in LAMR group (74.74±1.09, n=13) than in MR group (66.50±1.14, n=7) for both lip and nose segments. Scar hypertrophy developed in MR group with 28.6% and in LAMR group with 23.1%. No significant difference was noted in the ratio of lip length between LAMR and MR groups (0.84±0.08 and 0.73±0.10). These results suggest that LAMR is better than MR in repairing the unilateral complete cleft lip.

유경성 용종 형태로 발생된 신장 혈관근육지방종 1예

주현준 ( Hyun Jun Ju ),이강원 ( Kang Won Lee ),이유민 ( Yu Min Lee ),차정민 ( Jeong Min Cha ),신진호 ( Jin Ho Shin ),안선호 ( Seon Ho Ahn ),송주흥 ( Ju Hung Song ),서일영 ( Il Young Seo ),김헌수 ( Hun Su Kim ),조향정 ( Hyang Jung 대한신장학회 2007 Kidney Research and Clinical Practice Vol.26 No.3

흰쥐의 요도 손상후 협착 형성에 있어서 TGF-β_1의 역할

서일영,임정식 圓光大學校 醫科學硏究所 1995 圓光醫科學 Vol.11 No.2

Transforming growth factor-β_1 (TGF-β_1)is a homodimeric peptide of 25kDa involved in many fundamental biological processes including cell growth, extracellular matrix deposition and degradation, and inflammatory responses. Especially TGF-β_1 is released by platelet and inflammatory cells, and it affects all phases of the wound healing after injury. It contributes to the regulation of fibroblast chemotaxis and proliferation, and also controls the synthesis and degradation of extracellular matrix necessary for tissue repair. Clinically, scar tissue formation and subsequent stricture after urethral injury often result in troublesome problems to urologists. We intended to know the involvement of TGF-β_1 in the formation of stricture and histological changes after urethral injury of rats. We injured urethrae of 24 adult male Sprauge-Dawley rats(200-250g) by urethrotome and Dormia basket, and then observed histological changes and analysed TGF-β_1 mRNA levels by Northern blot. Northern blot analysis showed that TGF-β_1 mRNA was expressed for 1,3,and 5 days after injury. Fibroblasts and deposition of extracellular matrix were markedly increased on day 5. Reepithelialization was completed and urethral lumen was narrowed on day 10. Our results indicate that TGF-β_1 is involved in the formation of stricture after urethral injury and plays a critical role in early phase of tissue repair and fibrosis.

구강악안면 외상 환자의 창상 감염에 대한 임상세균학적 연구

서일영,유선열 전남대학교 치의학연구소 2003 구강과학 Vol.15 No.1

With increasing incidence of motor vehicle accidents and violent instrument-aided assaults, there has been a concomitant increase in oral and maxillofacial injuries. One of the greatest problems in achieving successful treatment for the injuries is wound infection. This study is to use selected antibiotics appropriately from bacteriological culture and antibiotic sensitive test for curing of wound and to prevent the infection by microorganism and also to prevent misusing and abusing antibiotics. A clinicobacteriological study was done in 40 patients with maxillofacial injuries treated in the Department of Oral and Maxillofacial Surgery of Chonnam University Hospital during the period of March 2002 though August 2002. Causative bacteria of wound contamination and infection were identified by bacteriological culture. Antibiotic sensitivity test was also done for the isolated bacteria. Clinical data were analyzed for the following issues: sex and age distribution, causes, types, site of injuries, and time elapsed from injury to treatment. Bacterial culture was positive in 29 out of 40 cases: 16 out of 20 fracture and laceration wounds, and 13 out of 20 simple laceration wounds. Frequently isolated bacteria were Streptococci viridans (24%), gram-positive bacilli (24%), Streptococcus salivalius (13%). and Staphylococcus species(13%). Streptococcus species were the most popular bacteria in the oral cavity (44.8%) and Staphylococcus species on the facial skin (27.3%). In comparison. Streptococcus species were the most popular bacteria in the oral cavity (41%)and Staphylococcus species the facial skin (53.6%) in normal healthy subjects. The positivity of bacterial culture was not related with causes of injury, ages, or sexes, but closely related with types and locations of the injuries and time intervals from injury to treatment. The injuries in the oral cavity (75.8%) were more positive in the bacterial culture than facial skin injury (63.6%) and complex lacerations (80%) were more positive in the bacterial culture than simple lacerations (65%). The patients who had a treatment from injury over 3 hours showed more positivity in the bacterial culture than those under 3 hours. The isolated bacteria were more sensitive to clindamycin, erythromycin, cefotaxim than to oxacillin, ampicillin and penicillin. In conclusion, effective antibiotics should be given judiciously in patients who have severe oral and maxillofacial trauma, who do not have proper treatment for hours, and who have simple injuries in oral cavity as well. Clindamycin, erythromycin, cefotaxim are effective as primary antibiotics in these cases.