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RISS 인기검색어
- 검색키워드
- 저자 : 서구종(Gu Jong Seo) (검색결과 4 건)
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서구종(Gu-Jong Seo),유선열(Sun-Youl Ryu),김옥준(Ok-Joon Kim),최홍란(Hong-Ran Choi) 대한구강악안면외과학회 2002 대한구강악안면외과학회지 Vol.28 No.1
The present study was carried out to evaluate the correlation of metastasis and prognostic factors in squamous cell carcinoma of head and neck. Examination was performed on a series of thirty-seven patients who were confirmed to squamous cell carcinoma and its lymphatic metastasis by pathologist. Correlations of metastasis and other factors such as angiogenesis, histologic grading, and p53 expression and ras oncogene were studied. The depth of tumors was around 1 to 27mm. Twenty cases were more than 10mm deep, of which seventeen cases were shown lymphatic metastasis. Total score of histologic grading including keratinization, nuclear atypia, growth pattern and intensity of inflammation was ranged from 5 to 10 points. Of these factors, nuclear atypia with intensity of inflammation, and nuclear atypia with growth pattern was correlated with nuclear atypia each. For angiogenesis, number of new-formed vessels were counted 13 to 58 each. Twenty-eight cases were shown to lymphatic metastasis. No correlation with histologic grading and lymphatic metastasis was found. The results of immunohistochemical staining for p53 and ras oncogene revealed that positive cases were 16 and 22, negative for 21 and 15 each. However, both were not correlated with histologic grading and lymphatic metastasis. These results were revealed that angiogenesis was not correlated with lymphatic metastasis of squamous cell carcinoma arising in head and neck. Nuclear atypia with intensity of inflammation and dysplasia with growth pattern were correlated with histologic grading, which suggested that more careful and adequate advice is needed for effective treatment.
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이종호(Jong Ho Lee),서구종(Gu Jong Seo),박광(Kwang Park),박기덕(Gi Deog Park),정무강(Moo Gang Chung),정중재(Jung Jae Jeong),정종철(Jong Cheol Jeong),박준아(Joon Ah Park) 대한구강악안면외과학회 1993 대한구강악안면외과학회지 Vol.19 No.3
We analysed the clinical datas obtained from 10 patients who underwent reconstructive microsurgery using venous autografts(male, 9 : female, 1 : range of age, 18-70 years old). The autologous veins were used to lengthen the pedicle in 6 cases. In the rest 4 cases, we used the autologous veins to reconstruct the defect of radial artery, lacrimal canaliculi, Wharton s duct and to guide the nerve regeneration, respectively. A length of long(7 cases) or small(3 cases) saphenous veins were harvested. Various types of venous graft with long saphenous vein and its branches(Medial femoral vein and external pudendal vein) were designed, including Y-, Loop- and interpositioning-type. These designs were very helpful when there were inadequate pedicle length, unsuitable recipient vessels. We could observe the patency in the repaired Wharton s duct and lacrimal canaliculi with good salivation and lacrimal drainage. Sensory was restored with the venous tubular guide. In conlusion, venous autografting was most reliable(success rate 90%) and useful technique that might be used in the field of oral and maxillofacial surgery.
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서구종,유선열 전남대학교 치과대학 2000 전남치대논문집 Vol.12 No.1
Examination was performed on a series of 37 patients who were confirmed to squamous cell carcinoma and its lymphatic metastasis by biopsy. Correlations of metasiatsis and other factors such as aginogenesis, histologic grading, and expression of p53 and ras oncogene were studied. The depth of tumors is around 1 to 27mm. 20 caseas were showed the depth of more than 10mm, of which 17cases were showed the lymphatic metastasis. Total score of histologic grading including keratinization, atypia, growth pattern and intensity of inflammation is ranged from 5 to 10 points. Of these factors, atypia with intensity of inflammtion, and atypia with growth pattern is correlated with atypia each. For angiogenesis, number of new formed vessels were counted 13 to 58 each. 28 cases shown the lymphatic metastasis. No correlation with histologic grading and lymphatic metastasis was found. The results of immunohistochemical staining for p53 and ras oncogene revealed that positive case is 16 and 22, negative for 21 and 15 each. Both were not correlated with histologic grading and lymphatic metastasis. Above results were reaveled that angiogenesis is not correlated with lymphatic metastasis in squamous cell carcinoma arising in head and neck region. Atypia with intensity of inflammtion and dyplasia with growth pattern are, however, correlated with histlogic grading, which suggest that more careful and adequate advice is needed to clinician.
ScienceON
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