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보문 : Mealan-a 세포에서 흰전동싸리 에탄올 추출물과 흑마늘 열수 추출물의 피부미백 효능
백현기 ( Hyun Gi Beak ),황지연 ( Ji Yeon Hwang ),홍성희 ( Sung Hee Hong ),김영철 ( Young Chul Kim ) 대한미용학회(구 대한미용과학회) 2015 대한미용학회지 Vol.11 No.1
This study was conducted in order to compare the whitening efficacy of Melilotus alba Medicus ethanol extract (MAEE) and black garlic water extract (BGWE). The total polyphenol contents of MAEE and BGWE were 122.65 and 5.5 mg/g, respectively, and the total flavonoid contents were 130.24 and 5.4 mg/g, respectively. The electron donating abilities of MAEE and BGWE at a concentration of 1,000 μg/mL were 74.4% and 37.2%, respectively. The maximum permissible levels of MAEE and BGWE in melan-a cells were ascertained as over 200 μg/mL. MAEE and BGWE at 50 μg/mL reduced the melanin contents by 27.5% (p/0.01) and 3.7%, respectively. MAEE and BGWE at 50 μg/mL reduced intracellular tyrosinase activity by 3.5% and 7.6%, respectively. Collectively, the results of this study suggested that MAEE and BGWE effectively inhibited melanin synthesis, while their tyrosinase inhibition activities were found to be weak. Additionally, the antioxidant activity and whitening efficacy of MAEE were higher than those of BGWE.
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청소년의 스마트폰 중독과 마음건강과의 관계에서 학교생활적응의 매개효과
하태현 ( Tai Hyun Ha ),백현기 ( Hyeon Gi Beak ) 한국컴퓨터교육학회 2014 컴퓨터교육학회 논문지 Vol.17 No.6
본 연구는 스마트폰 중독에 영향을 미치는 요인으로서 마음건강의 주 효과를 검증하고, 이들 관계에 학교생활적응의 매개효과를 검증해봄으로써 스마트폰 중독 예방을 위한 다양한 실천적 함의를 제공하는데 그 목적이 있다. 이를 위해 스마트폰을 사용하는 지역 소재 초등학교 260명을 대상으로 설문조사를 실시하였다. 스마트폰 중독, 마음건강 및 학교생활적응 간의 관계를 구조방정식 모형으로 설정해 학교생활적응의 매개효과를 검증하였다. 연구결과 학교생활적응은 마음건강과 스마트폰 중독 사이의 관계를 완전히 매개하는 변인으로 나타났다. 학교생활적응의 매개효과는 Sobel 검증을 통해서 통계적 유의미성이 검증되었다. 이러한 결과는 마음건강이 학교생활적응과 같은 부정적 정서의 발생을 감소시켜주며, 이는 다시 스마트폰의 중독적 사용 가능성을 낮춰주는데 영향이 있음을 제시하고 있다. 이를 토대로 본 연구는 스마트폰 중독 예방을 위해 마음건강 향상과 같은 보호요인의 강화 노력이 무엇보다 중요하며, 매개 변인으로서 스마트폰 중독에 영향을 미치는 학교생활적응과 같은 위험요인을 관리하기 위한 장·단기적 개입이 필요하다는 점을 시사하고 있다. This study aims to offer a wide range of practical implications for Smartphone addiction prevention by verifying the effect of mind health as a factor that is influenced by Smartphone addiction, and testing the relationships between Smartphone addiction and mind health with school life adaptation as a mediation effect. For this research, a survey was conducted of 250 elementary school students who use Smartphones. The relationships between Smartphone addiction, mind health and school life adaptation were set as the structural equation model, and they were verified by the mediation effect of school life adaptation. The results showed that school life adaptation turned out to be an entirely mediating variable on the relationship between mind health and Smartphone addiction. The statistical significance of the effect on school life adaptation was verified by the Sobel test. The mediation effect resulted in mind health reducing the occurrence of negative emotion of school life adaptation, and also reinforced decreased Smartphone use.
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보문 : 인체피부섬유아세포에서 자주달개비 메탄올 추출물의 항노화 효능
황지연 ( Ji Yeon Hwang ),백현기 ( Hyun Gi Beak ),박별례 ( Byoul Rye Park ),김영철 ( Young Chul Kim ) 대한미용학회(구 대한미용과학회) 2015 대한미용학회지 Vol.11 No.1
The objectives of this study were to evaluate the effects of Tradescantia reflexa methanol extract (TRME) on collagen synthesis and the inhibition of collagen degradation in human dermal fibroblasts. Total polyphenolics and flavonoids in the TRME were 148.3 mg/g and 95 mg/g, respectively. At concentration of 1,000 μg/mL, the electron donating ability of TRME was 10.3%. Collagenase and elastase inhibition of TRME at 10 mg/mL was 82.5% and 49.8%, respectively. As determined with a 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay, the maximum permissible level for treating human dermal fibroblasts with TRME was shown to be over 200 μg/mL. In comparison with the control, TRME at 200 μg/mL significantly (p/0.01) increased type I procollagen synthesis by 58.9%, while TRME at 200 μg/mL significantly (p/0.01) decreased matrix metalloproteinase-1 mRNA expression by 49.1%. These results suggested that TRME had very low toxicity in human dermal fibroblasts, and had high efficacy on the stimulation of collagen synthesis and the inhibition of collagen degradation in human dermal fibroblasts. Therefore, TRME may be used as a functional cosmetic material for the prevention or alleviation of skin-wrinkle formation induced by ultraviolet rays.
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