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배영덕 ( Young Deok Bae ),김수진 ( Soo Jin Kim ),남택만 ( Teck Man Nam ),조한수 ( Han Su Cho ),노승혁 ( Seung Hyuk Rho ),윤덕형 ( Duck Hyoung Yoon ),윤종우 ( Jong Woo Yoon ),이삼열,남은숙,오국환 ( Kook Hwan Oh ),채동완 ( Dong Wan Cha 대한신장학회 2002 Kidney Research and Clinical Practice Vol.21 No.6
Immunosuppressive medications after renal allograft transplantation have impacted the course of acute and chronic rejection; however, they have no defined effects on the prevention of recurrent and Glomerulonephritis (GN) in an allograft kidney. Authors experienced a case of rapidly progressive glomerulonephritis (RPGN). The 35-year-old female patient developed a rapid deterioration of renal function 4 years after renal transplantation. The allograft biopsy showed crescentic glomerulonephritis evolving from membranoproliferative glomerulonephritis (MPGN) type Ⅰ. She was given pulse steroid and oral cyclophosphamide therapy immediately after the renal biopsy. Graft function stabilized and proteinuria decreased even though graft function did not recover to pre-treatment level and low grade proteinuria persisted.
손경민 ( Kyeong Min Son ),서영일 ( Young Il Seo ),김인제 ( In Je Kim ),배영덕 ( Young Deok Bae ),정영옥 ( Young Ok Jung ),차명진 ( Myeong Jin Cha ),김현아 ( Hyun Ah Kim ) 대한류마티스학회 2010 대한류마티스학회지 Vol.17 No.2
Objective: Gout is crystal-induced arthritis with hyperuricemia. Uric acid lowering agent (UALA) is the maintenance drug of its treatment. Drug adherence is an important factor that influences treatment outcome. The purpose this study was to examine the drug adherence to UALA of 303 gouty patients and to analyze the factors associated with compliance. Methods: We retrospectively assessed adherence to UALA in 303 patients who visited three hospitals affiliated with Hallym University. Patients were diagnosed as gout and used UALA with at least 6 month follow-up. Two adherence measures were calculated, the percentage of days covered (PDC) and the time until an extended break (at least 60 days) in treatment. A PDC <70% was considered poor adherence and factors associated with poor adherence were examined. Results: Among the 303 patients, 283 (93.4%) were male. Mean age was 55.4±13.7 years. Comorbidities included hypertension in 117 (38.6%), diabetic mellitus in 108 (35.6%), angina in 107 (35.3%), myocardial infarction in 108 (35.6%), and heart failure in 113 (37.3%). The mean PDC was 65.8% with 63.4% of patients considered poorly compliant over the study period. Mean treatment duration before an extended break occurred was 203.5 days. Factors associated with good adherence included hypertension and prescription from rheumatologist. Conclusion: In our study, adherence to UALA in gouty patient was poor. Understanding the factors associated with adherence to UALA and proper education of gouty patients to improve drug adherence are needed.
최효진 ( Hyo Jin Choi ),신기철 ( Ki Chul Shin ),배영덕 ( Young Deok Bae ),이정찬 ( Jung Chan Lee ),김진현 ( Jin Hyun Kim ),강은하 ( Eun Ha Kang ),임철현 ( Churl Hyun Im ),이은봉 ( Eun Bong Lee ),송영욱 ( Yeong Wook Song ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.1
1. Protein-losing enteropathy is a rare complication of autoimmune diseases. We report a case of primary Sjogren`s syndrome with protein-losing enteropathy in 50-year-old female who complained of generalized edema. Protein-losing enteropathy of the small intestine was demonstrated by Tc-99m labeled albumin abdominal scintigraphy. Duodenal biopsies showed chronic inflammatory cell infiltration without lymphangiectasis or vasculitis. The patient received oral prednisolone (60 mg/day) for 4 weeks with subsequent clinical improvement. Primary Sjogren`s syndrome or other autoimmune diseases should be considered in cases of protein-losing enteropathy.
식도 이완 불능증과 간질성 폐렴을 동반한 전신성 홍반성 낭창
권혜리 ( Hye Lee Kwon ),홍경욱 ( Kyung Wook Hong ),임승진 ( Seung Jin Lim ),박소영 ( So Young Park ),배영덕 ( Young Deok Bae ),김경호 ( Kyung Ho Kim ),최정희 ( Jeong Hee Choi ),모은경 ( Eun Kyung Mo ),박용범 ( Yong Bum Park ) 대한결핵 및 호흡기학회 2008 Tuberculosis and Respiratory Diseases Vol.65 No.4
Systemic lupus erythematosus (SLE) is a multisystem disorder where the etiology is not clearly known. Symptomatic chronic interstitial pneumonitis is an uncommon manifestation, with a reported prevalence of 3∼13%. Achalasia is rare disease that presents with failure in the relaxation of the esophagus sphincter. A 22-year-old woman was admitted to our hospital because of fever, cough and dyspnea. The patient had a history of pericardial effusion and Raynaud`s phenomenon. The results of laboratory tests indicated the presence of lymphopenia and included positive antibody tests for antinuclear antibody and anti Sm antibody. A chest X-ray demonstrated the presence of peribronchial infiltration on both lung fields. A Chest CT image showed interlobar septal thickening, ground-glass opacity and a honeycomb appearance in both lung fields and esophageal dilatation with air fluid level. An esophagogram showed the presence of dilated esophagus ends that represented the non-relaxed lower esophageal sphincter. Manometry demonstrated incomplete sphincter relaxation. The case was diagnosed as systemic lupus erythematosus associated with interstitial pneumonia and achalasia. (Tuberc Respir Dis 2008;65:323-327)