비대칭 마그네트론 스퍼터링 방법으로 증착한 초경도 탄화규소 박막

배경은 ( Kyung Eun Bae ),채기웅 ( Ki Woong Chae ),박종극 ( Jong Keuk Park ),이욱성 ( Wook Seong Lee ),백영준 ( Young Joon Baik ) 대한금속재료학회(구 대한금속학회) 2015 대한금속·재료학회지 Vol.53 No.8

The effect of sputter target power and substrate bias voltage on the deposition of silicon carbide thin film was investigated. Films were deposited using unbalanced magnetron sputtering method with sintered silicon carbide target connected to a direct current electric power from 50 to 200 W. Ar gas was used as a sputtering gas. The distance between the target and the substrate was 7.5 cm and the deposition pressure was 3 m Torr. We used a Si single crystal wafer as a substrate, which was heated at 450℃. The substrate bias voltage was varied between 0 and -100V. Deposited films consisted of columnar grains with several nm width, which formed a texture whose orientation was influenced by the bias voltage. Most of the grains were crystalline which was confirmed by transmission electron microscopy. The hardness measured by a nano-indentation method showed a super-hardness of about 50 GPa. (Received September 17, 2014)

비대칭 마그네트론 스퍼터링 방법에 의한 탄화붕소박막의 증착거동

배경은 ( Kyung Eun Bae ),박종극 ( Jong Keuk Park ),이욱성 ( Wook Seong Lee ),배영준 ( Young Joon Baik ) 대한금속재료학회(구 대한금속학회) 2014 대한금속·재료학회지 Vol.52 No.12

The effect of temperature and substrate bias on the deposition behavior of boron carbide (BC) thin film was studied. BC thin films were deposited by an unbalanced magnetron sputtering (UBM sputtering) method. The B4C target was connected to a DC power supply at 200 W and sputtered by ionized argon gas. The distance between the substrate and target was 7.5 cm and the deposition pressure was 3 mTorr with argon gas. Silicon substrates were heated by halogen lamps from room temperature to 450 ℃. DC bias voltage applied to substrates up to .100 V. The deposited films showed no diffraction peak on either X-ray diffraction and transmission electron microscopy analysis, which indicated an amorphous nature of the films irrespective of deposition temperature and substrate bias in this study. Only a 1280 cm.1 absorption peak of Fourier transform infrared spectroscopy was observed. The hardness of the BC films was about 40 GPa regardless of deposition temperature.

Development of Online Continuing Education Courses on National Health Examination for Community Health Nurses: Using the Rapid Prototyping Method

Eun-Ha Kim(김은하),Kye-Ha Kim(김계하),Kyung-Eui Bae(배경의) 한국산학기술학회 2019 한국산학기술학회논문지 Vol.20 No.8

본 연구의 목적은 방문간호사를 위한 국가 건강검진에 관한 온라인 보수교육 프로그램을 개발하기 위함이다. 연구 기간은 2016년 11월부터 2017년 12월까지 시행되었다. 교육 프로그램은 래피드프로토타입 방법을 활용하여 단계적으로 개발하였다. : 1) 관련 문헌 검토와 이해관계자 및 전문가의 포커스그룹 면담(FGI)을 통해 학습자의 요구도를 확인하였다. 2) 방문 간호사의 건강 검진에 관한 상담 전략을 포함하는 교육내용의 개요를 작성하였다. 3) 온라인 교육자료 개발자와 연구자가 회의를 거쳐 온라인 교육 프로그램을 개발하여 학습자에게 모의 조사를 실시하였다. 4) 확정된 교육내용을 8개의 모듈로 구분하여 온라인 교육 자료 초안을 개발하여 파일롯 과정을 실행하였다. 5) 학습자의 피드백을 반영하여 교육 프로그램을 확정하여 지역사회 간호사를 위한 건강검진 온라인 보수교육 프로그램을 최종적으로 개발 및 운영하였다. 개발 된 온라인 보수교육 프로그램은 방문 간호사가 건강검진에 관한 상담을 수행하도록 돕는 데 효과적이었다. 따라서 온라인 보수교육 프로그램은 간호사의 실무역량을 향상하는데 효과적인 교육적 접근이라 할 수 있겠다. This study was conducted to develop an online education program for visiting health nurses on National Health Examination. The study period was from November 2016 to December 2017. The program was developed in stages using rapid prototyping methodology. 1) Learners" needs were identified through literature review and focus group interviews (FGIs) with visiting health nurses and stake-holders in the field. 2) The contents of the education program including counseling strategies regarding the heath of visiting health nurses were developed. 3) Online education materials were developed and piloted amongst learners. 4) The contents of educational programs were classified into eight learning modules, and online education drafts were pilot tested. 5) Based on feedback from learners, this program was revised and a web-based continuing education program for community nurses was developed. These education programs effectively assisted nurses with counseling regarding health examinations during visiting health nursing care. Therefore, the online continuing education program may be a very effective educational approach to improving nurses competency.

생마 신선편이 제조를 위한 천연 향신료의 항균, 항산화 및 항혈전 활성 평가

류희영,배경화,금은주,박상조,이봉호,손호용,Ryu, Hee-Young,Bae, Kyung-Hwa,Kim, Eun-Joo,Park, Sang-Jo,Lee, Bong-Ho,Sohn, Ho-Yong 한국생명과학회 2007 생명과학회지 Vol.17 No.5

천연 향신료를 이용한 기능성 생마 신선편이 제조를 위해, 국내외에서 사용되는 향신료들을 대상으로 물 추출물 및 메탄을 추출물을 제조하였다. 향신료의 추출효율은 향신료에 따라, 추출용매에 따라 큰 차이를 나타내었으며, 추출물들의 성분 분석 결과 향신료의 우수한 영양학적 특성을 확인하였다. 먼저 물 추출물들의 항균, 항산화 및 항혈전 활성을 검토한 결과, 물 추출물들은 항균활성을 나타내지 않았으며, 페퍼민트 추출물에서 트롬빈 타임이 26배 이상 연장되어 강력한 항혈전 활성을 확인하였으며, DPPH 소거능 평가결과 계피 및 로즈마리 추출물에서 각각 $61.3{\mu}g/ml$ 및 $84.3{\mu}g/ml$의 $IC_{50}$를 확인하였다. 한편 메탄을 추출물들에서는 타임, 생강, 및 계피 추출물이 생마 저온부패균에 대해 항균력을 나타내었으며, 로즈마리 추출물은 생마 저온부패균에 대한 항균력은 없었으나, 강력한 항충치균 활성을 나타내었다. 또한 계피 및 산초 추출물에서 우수한 항혈전 활성을, 타임 및 계피 추출물에서 강력한 DPPH 소거능을 확인하였다. 따라서 항산화 및 항혈전 활성이 동시에 우수한 페퍼민트 및 계피 물 추출물들을 이용하여 기능성 생마 신선편이를 제조하였으며, 제조된 신선편이는 $4^{\circ}C$에서 24시간 보관 후에도 페퍼민트 및 계피 유래의 항산화 및 항혈전 활성을 유지하였다. 이러한 결과는 천연 향신료를 이용하여, 저장성이 우수하면서, 기능성, 관능성이 강화된 신선편이 제조가 가능함을 제시하고 있다. To make functional fresh-cut yam using natural spices, the water or the methanol extract was prepared from different kinds of natural spices including ginger, wasabi, black pepper, mustard, cinnamon, chinese pepper, garlic, thyme, rosemary, chamomile, and peppermint. The extraction yields were varied as spice sources and extraction solvents used. Among the water extracts, peppermint extract showed strong antithrombosis activity with 26-folds extended thrombin time, and the $IC_{50}s$ of the extracts from cinnamon and rosemary were $61.3{\mu}g/ml\;and\;84.3{\mu}g/ml$ in DPPH scavenging assay, respectively. Whereas, the antimicrobial activity of all water extracts was ignorable. Among the methanol extracts, the extracts from thyme, ginger, and cinnamon showed antimicrobial activity against yam putrefactive bacteria. Strong antioxidative activity was found in the extracts from cinnamon and thyme. Based on these results, the functional fresh-cut yam was prepared using the water extract from peppermint or cinnamon. The antioxidative and antithrombin activities in the fresh-cut yam were maintained at $4^{\circ}C$ for 24 hr. Our results suggest that the natural spices could be applied to production of functional fresh-cut yam.

Simple Sequence Repeat (SSR) Marker를 이용한 토마토 품종 식별

권용삼,박은경,배경미,이승인,박순기,조일호,Kwon, Yong-Sham,Park, Eun-Kyung,Bae, Kyung-Mi,Yi, Seung-In,Park, Soon-Gi,Cho, Il-Ho 한국식물생명공학회 2006 식물생명공학회지 Vol.33 No.4

국내에서 유통되고 있는 토마토 품종의 판별 방법에 SSR marker의 이용 가능성에 대한 연구를 수행하여 얻어진 결과를 요약하면 다음과 같다. 토마토 28품종을 18개의 SSR marker를 이용하여 분석하였을 때 대립유전자의 수는 $2{\sim}9$개로 비교적 다양한 분포를 나타내었으며 전체 60개의 대립유전자가 분석되었다. PIC 값은 $0.476 {\sim}0.800$ 범위에 속하였으며 평균값은 0.607로 나타났다. SSR marker를 이용하여 작성된 토마토 28품종의 품종간 유전적 거리는 $0.35{\sim}0.97$의 범위로 나타났고, 유사도 지수 0.36을 기준으로 할 때 28개 품종은 체리형 토마토 그룹과 일반형 토마토 그룹으로 나눌 수 있었으며, 공시 품종 모두 SSR marker의 genotype에 의해 뚜렷이 구분되었다. 이 연구결과는 토마토의 품종식별에 기초 자료로 유용하게 이용될 수 있는 것으로 나타났다. This study was carried out to evaluate the suitability of simple sequence repeat (SSR) markers for varietal identification and genetic diversity in 28 commercial tomato varieties. The relationship between marker genotypes and 28 varieties was analyzed. Of the 219 pairs of SSR primers screened against ten tomato varieties, 18 pairs were highly polymorphic with polymorphism information content (PIC) ranging from 0.467 to 0.800. Among the polymorphic loci, two to nine SSR alleles were detected for each locus with an average of 3.3 alleles per locus. Genetic distances were estimated according to Jaccard's methods based on the probability that the amplified fragment from one genotype would be present in another genotype. These varieties were categorized into cherry and classic fruit groups corresponding to varietal types and genetic distance of cluster ranging from 0.35 to 0.97. The phonogram discriminated all varieties by marker genotypes. The SSR markers proved to be useful variety identification and genetic resource analysis of tomato.

결혼이주여성이 임신·출산과정에서 체험한 갈등경험

김은하(Kim Eun-Ha),박형숙(Park Hyoung Sook),배경의(Bae Kyung Eui) 질적연구학회 2012 질적연구 Vol.12 No.1

Purpose: This study aimed to explore the structure of meaning on conflict experienced by married immigrant women during pregnancy and childbirth. Methods: A phenomenological approach was used. Participants were five immigrant women who had experienced pregnancy and childbirth in Korea. Data were collected by in-depth interviews. The method proposed by Giorgi (1997) was used to guide the process data analysis. Results: The structure of meaning which emerged from constituents was: Overcame absence of family relationship and became "Korean-mother." It explored the essence of conflict experienced by married immigrant women during pregnancy and childbirth, which reflected the four phenomenological structures of space, body, time, and relationship: Became a person who gained no respect from one's spouse; left out in a place where access to medical information and health care provider were blocked; endured time of loneliness and isolation from in-laws and people around; accepted the new child-centered family relationships. Conclusion: This study provided an understanding on conflict experienced by married immigrant women during pregnancy and childbirth. The findings of this study could be utilized for a nursing intervention to take care of conflict experienced by married immigrant women during pregnancy and childbirth.

분산제 함량에 따른 전도성 카본블랙의 분산 특성 및 스크린 인쇄된 OTFTs용 소스-드레인 전극 물성

이미영(Mi Young Lee),배경은(Kyung Eun Bae),김성현(Seong Hyun Kim),임상철(Sang Chul Lim),남수용(Su Yong Nam) 한국고분자학회 2009 폴리머 Vol.33 No.5

Simple sequence repeat (SSR) marker를 이용한 벼 품종 식별

권용삼,박은경,박찬웅,배경미,이승인,조일호,Kwon, Yong-Sham,Park, Eun-Kyung,Park, Chan-Ung,Bae, Kyung-Mi,Yi, Seung-In,Cho, Il-Ho 한국생명과학회 2006 생명과학회지 Vol.16 No.6

SSR markers를 이용하여 벼의 품종간 유전적 유연관계 분석과 품종식별 방법에 대한 연구를 수행하여 얻어진 결과를 요약하면 다음과 같다. SSR primer 50개와 벼 보급종 21품종을 PCR 반응시킨 결과 다형성을 뚜렷하게 나타내는 primer는 23개였으며, 각 marker에 의해 발생된 대립유전자의 수는 $2{\sim}9$까지 검출되었고, 평균값은 3.00개로 나타났다. 유전적 다형성 정도를 나타내어 주는 SSR marker의 PIC 값은 최소 0.091에서부터 최대 0.839까지 다양하게 분석되었다. SSR marker를 이용하여 분석된 벼 21품종에 대한 전체 유전적 유사도는 $0.59{\sim}0.92$의 범위에 속하였고 유사도 지수 0.65를 기준으로 할 때 4개의 그룹으로 구분되었다. SSR marker중에서 RM206, RM225, RM418, RM478은 marker genotype에 의해 21 품종에 대해 각각 고유한 밴드 특성을 나타내어 품종판별이 가능한 것으로 나타났다. 금후 이 연구결과는 벼 보급종의 품종식별을 위해 효과적으로 이용될 수 있는 것으로 나타났다. The objective of this study was carried out to evaluate the suitability of simple sequence repeat (SSR) markers for genetic diversity assessment and identification of rice varieties. The 23 primers selected from 50 SSR primers showed polymorphisms in the 21 rice varieties. The 2 to 9 SSR alleles were detected for each locus with an average of 3.00 alleles per locus. The polymorphism information content (PIC) ranged form 0.091 to 0.839. Based on band patterns, UPGMA cluster analysis was conducted. These varieties were separate into 4 groups corresponding to rice ecotype and pedigree information and genetic distance of cluster ranging from 0.59 to 0.92. The 4 SSR primer sets (RM206, RM225, RM418, RM478) selected form 23 polymorphic primers were differentiated all the rice variety from each other by markers genotypes. These markers may be used wide range of practical application in variety identification of rice.

조현병 환자에서 비정형 장기지속형 주사제와 경구제의 6개월 추적관찰 기간 효과비교

박찬미(Chan mi Park),박은정(Eun jung Park),이승환(Seung Hwan Lee),김영훈(Young Hoon Kim),정영철(Young Chul Chung),원승희(Seung hee Won),이상규(Sang Kyu Lee),박선철(Seon Cheol Park),배경열(Kyung ryul Bae),최진아(Jin A Choi),최하진(Ha 한국보건의료연구원 2016 근거와 가치 Vol.2 No.2

Objectives: To compare the clinical outcomes between the schizophrenia patients using long-acting injection (LAI) and those using oral agent (Oral). Methods: A prospective multicenter registry conducted at 7 hospitals comparing a one-year treatment effectiveness of LAI to reduce recurrence and to improve medication adherence (MA) and quality of life (QOL). This interim analysis presents data from the first 6 months of the follow-up period. Results: Among a total of 393 patients enrolled in this study, 385 patients (LAI 87, Oral 298) were analyzed as the interim analysis. There were no significant differences in clinical global impression (CGI), global improvement (GI), positive and negative symptom scale (PANSS), and QOL (CGI, P=0.618; GI, P=0.599; PANSS, P=0.289; EuroQol five dimensions questionnaire, P=0.254; Korean version of 4th revision of Schizophrenia Quality of Life Scale, P=0.416; visual analogue scale, P=0.581). LAI was associated with improved doctor’s perspective MA (P=0.021), but no difference was observed in patient’s perspective MA (P=0.355). Recurrence for 6 months occurred in 8 cases (9.2%) of LAI and in 43 cases (14.4%) of Oral. Kaplan-Meier analysis showed that there was no significant difference in time to recurrence after enrollment between LAI and Oral. The multivariate Cox analysis also showed no difference (hazard ratio=1.710; 95% confidence interval=0.758~3.855). Conclusion: In patients with schizophrenia experiencing recurrence, the difference of effectiveness between LAI and oral therapy could not be observed during 6 months of follow-up.

발효, 세포배양, 생물공정 시판 전통주의 항균, 항산화 및 항혈전 활성 평가

류희영 ( Hee Young Ryu ),금은주 ( Eun Jo Kum ),배경화 ( Kyung Hwa Bae ),김영관 ( Young Kwan Kim ),권인숙 ( In Sook Kwun ),손호용 ( Ho Yong Sohn ) 한국미생물생명공학회 2007 한국미생물·생명공학회지 Vol.35 No.3