http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
박효정 ( Hyo Jung Park ) 한국정맥경장영양학회 2015 한국정맥경장영양학회지 Vol.7 No.2
Glutamine is the most abundant amino acid, composed of more than 50 percent of free amino acid in the human body. It had been regarded as a conditional essential amino acid and its concentration is markedly reduced in critically ill patients with trauma, burn, or sepsis. From the early 1990s, many parenteral glutamine studies on critical illness have reported the benefits in mortality, infection, and length of stay. However, its clinical efficacy was based on out-of-date, smaller, single-center studies. Clinical effects of parenteral glutamine have shown no benefits or even harms in recent clinical trials and meta-analysis. Furthermore, it has challenged the hypothesis that low plasma glutamine concentration was associated with poor outcomes in critically ill patients. Although many studies showing the efficacy of glutamine have been reported, parenteral glutamine supplementation may be harmful in patients with multiorgan failure or baseline kidney dysfunction. Further studies should be conducted to identify the use of glutamine supplementation in combination with parenteral and enteral nutrition or enteral/oral nutrition alone, specific adult or pediatric patients, the appropriate time and doses for administration of glutamine, cost-benefit analysis, and the exact mechanisms of action.
장부전 환자의 장재활 시스템 구축을 위한 질 향상 활동
박효정 ( Hyo Jung Park ),이상훈 ( Sang Hoon Lee ),윤지혜 ( Ji Hye Yoon ),김현정 ( Hyun Jung Kim ),홍슬희 ( Seul Hee Hong ),김은주 ( Eun Ju Kim ),민자경 ( Ja Kyung Min ),김현정 ( Hyun Jung Kim ),정보경 ( Bo Kyung Jung ),오채연 ( Ch 한국정맥경장영양학회 2014 한국정맥경장영양학회지 Vol.6 No.3
Purpose: Intestinal failure (IF) is a complex clinical condition requiring a multi-disciplinary team approach. Our objective was to set up the treatment protocols and education documents for IF patients for development of intestinal rehabilitation programs in our hospital. Methods: We compared the number of inpatients, length of hospital stay, mode of nutrition and calorie supply at discharge, and the frequency of blood transfusions before and after quality improvement of multidisciplinary activities, in order to evaluate the indirect effects of new protocols and training materials and for development of the intestinal rehabilitation system. Results: We integrated eleven protocols for treatment and monitoring and seven educational materials for patients and caregivers. We compared indirect effects before and after the quality improvement activities. The number of IF patients hospitalized was reduced from 12 to 9. The mean days of hospital stay was decreased from 322 days to 73 days, the average number of monthly blood transfusions was also reduced from 1.8 to 0.3. In addition, the percentage of patients administered enteral nutrition and calories supplied was increased at discharge. Conclusion: By integrating IF protocols and education materials for IF patients, we found possible indirect effects of intestinal rehabilitation using a multidisciplinary team approach.
뮤즐리 식사 대용식이 비만 중년여성의 체중감량과 혈액성분에 미치는 영향
박효정 ( Hyo Jung Park ),홍양희 ( Yang Hee Hong ),정은영 ( Eun Young Jung ),김선희 ( Seon Hee Kim ),전승철 ( Seung Cheol Jun ),장은재 ( Un Jae Chang ) 한국미용학회 2010 한국미용학회지 Vol.16 No.2
This study was designed to investigate the effects of weight control and changes in serum components using a commercial muesli meal replacements diet on 23 obese middle aged women (body mass index, BMI>25) over a period of 4 weeks. Muesli meal replacements contain that are consisted of mainly whole grain, seeds, and nuts ingredients. The subjects had muesli meal replacement (38 g) with milk or soymilk once a day instead of breakfast. The mean weight was significantly decreased from 63.0±8.0 kg to 61.6±7.7 kg after 4 weeks (p<0.001). Body mass index (p<0.001), fat mass (p<0.01), lean body mass (p<0.01), and waist size (p<0.001) were also significantly decreased after experimental period. The concentration of serum glucose (p<0.05), total cholesterol (TC) (p<0.01), and low-density lipoprotein (LDL) cholesterol (p<0.05) were significantly decreased during experimental period. Our results show that muesli meal replacements are effective in the diet therapy of obese middle aged women.
국내 입원한 성인 암환자의 정맥영양 사용에 대한 후향적 연구
박효정 ( Hyo Jung Park ),손유민 ( You Min Sohn ),정지은 ( Jee Eun Chung ),김정태 ( Jung Tae Kim ),양진아 ( Jin A Yang ),배혜정 ( Hye Jung Bae ),성예원 ( Ye Won Sung ),김선화 ( Sun Hwa Kim ),조지윤 ( Ji Yoon Cho ),정경미 ( Kyung Mi 한국정맥경장영양학회 2020 한국정맥경장영양학회지 Vol.12 No.2
Purpose: There have been no clinical studies on the characteristics of parenteral nutrition (PN) for adult cancer inpatients in South Korea. The published evidence describing modern PN practices in these patients is also extremely limited. Therefore in this retrospective multicenter cross-sectional study, we aimed to investigate the PN support practice in hospitalized adult cancer patients. Methods: The study included adult cancer patients hospitalized in nine hospitals in South Korea and received PN, during the period from August 1st, 2017 to October 30th, 2017. We evaluated the relevant hospital-based PN practices in this group. Results: Among the 11,580 inpatient admissions during this period, 759 cancer patients received PN (6.6%). The majority of enrolled patients (97.2%) used commercially available PN and 71.2% of these used peripheral PN formulations. The average in-hospital PN duration was 16.1±19.9 days. Patients received only 65.4±25.4% calories of the recommended target calories. The in-hospital mortality of enrolled patients was 26.1%. Conclusion: We conclude that commercial PN is the most common form of PN administered to hospitalized adult cancer patients and the overall in-hospital mortality in the patients using PN is higher in South Korea compared to other countries.
연하장애가 있는 신경계 이상 환아에서 경피 내시경하 위루술 후 흡인성 폐렴의 빈도 감소
박효정(Hyo Jung Park),강지현(Ji Hyun Kang),김정미(Jung-mi Kim),추미애(Mi Ae Chu),최병호(Byung-Ho Choe),서혜은(Hye Eun Seo),권순학(Soonhak Kwon) 대한소아신경학회 2011 대한소아신경학회지 Vol.19 No.2
목적 : 스스로 먹을 수 없는 사람의 경우 타인에 의해 음식물을 공급하는 방법은 비위관을 통하거나 위루관을 통한 방법이 있다. 이중 내시경을 통한 위루술 후에 호흡기 감염의 감소 등의 유익을 확인하고자 연하장애가 있는 신경계 환아들을 대상으로 본 연구를 시행하였다. 방법 : 경북대학교병원 소아청소년과에서 1999년 1월부터 2008년 12월까지 연하장애가 있는 신경계 이상환자 중 경피 내시경하 위루술을 시행 받고 시술 후 12개월 이상 경과 관찰된 26명을 대상으로 환자들의 특성을 조사하고 기저 질환별로 분류하였으며 시술 전후에 체중과 흡인성 폐렴으로 입원하게 되는 횟수를 비교하였다. 시술 전과 시술 후 6개월 및 시술 후 6-12개월을 기간으로 정하여 비교하였다. 결과 : 총 26명(남자 14)의 시술 당시 평균 나이는 6.4±4.7 (0.9-16.9)세였다. 절반 이상인 16명의 체중이 또래에서 3 백분위수 미만이었다. 기저질환으로는 뇌성마비가 16명, 후천적 뇌손상이 4명, 척수성 근위축증이 3명, 신경계 퇴행성 질환과 선천성 근위축증이 각각 2명과 1명 이었다. 시술 전과 시술 후 6개월 및 6-12개월에 체중에는 유의한 증가가 없었다. 시술 전의 흡인성 폐렴의 빈도는 전체환자에서 6개월 간 평균 2.2회 였고 시술 후 6개월 이내에는 평균 0.35회, 6에서 12개월 이내에는 평균 0.27회로 유의한 감소가 있었다(P =0.000). 결론 : 경피 내시경하 위루술은 연하곤란을 보이는 신경질환 환아에서 흡인성 폐렴의 빈도를 감소시킬 수 있는 유용한 시술로 생각한다. Purpose : Nasogastric tube or percutaneous endoscopic gastrostomy (PEG) tube can provide a means of feeding when oral intake is not adequate. This study aimed to evaluate the benefits of PEG such as reduced respiratory complications in neurodisabled children with dysphagia. Methods : Twenty-six neurodisabled patients with dysphagia were followed-up after PEG for at least 12 months from 1999 to 2008. Medical records including characteristics, body weight, frequency of aspiration pneumonia, and grade of gastroesophageal reflux (GER) were reviewed retrospectively between the time before and after PEG. The data collected before PEG was compared with those at 0-6 months and 6-12 months after PEG. Results : The 26 (male 14) enrolled patients had a mean age on PEG of 6.4±4.7 (0.9-16.9) years. The body weight percentile of 16 out of 26 patients was under the 3rd percentile. Underlying diseases were cerebral palsy (n=16), acquired braininjury (n=4), spinal muscular atrophy (n=3), neurodegenerative disease (n=2), and congenital muscular dystrophy (n=1). Body weight was not significantly different before and after PEG. The frequency of aspiration pneumonia was 2.2 times per 6 months before PEG, compared to 0.35 times (0-6 months) and 0.27 times (6-12 months) after PEG, which showed a significant difference (P =0.000). Conclusion : The frequency of aspiration pneumonia decreased significantly by PEG in neurodisabled children with dysphagia.