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박준성,전유종,나재호,조수연,신양진,신외경,김준호 한국자동차공학회 2022 한국 자동차공학회논문집 Vol.30 No.10
This paper proposes a high-efficiency power module for electric vehicle fast charger application. The power module consists of a three-phase vienna rectifier and an isolated LLC resonant converter designed to achieve high efficiency at peak current when the battery voltage is from 150 V to 1000 V, which is the commercially fast charging requirement for 400 V and 800 V batteries. The DC-link voltage control of PFC as well as duty adjustment, frequency control, and half/full-bridge switching of LLC resonant converter are proposed to cover a wide battery voltage range. A 20 kW prototype of the proposed power module is built and tested to verify performance. The peak efficiency of one power module was 96.5 %, which was measured 2 %p higher than that of the Infypower’s 20 kW power module. In order to verify the proposed constant current control and pre-charging sequence, the effectiveness of the parallel-connected power modules was also validated on an 80 kW prototype. Owing to identical hardware and software in each power module, the proposed power module can easily expand the power up to 400 kW for ultra-fast charging.
박준성,김현수,이종욱,양말숙,강석윤,김재홍,--,조혜진,정철권,조도연,최진혁,임호영,김효철 대한조혈모세포이식학회 2001 대한조혈모세포이식학회지 Vol.6 No.1
연구배경: 고용량 항암 화학 요법 및 자가 조혈모세포 이식술은 임상적 관해를 유도하기 위한 새로운 치료 접근방법 이지만 미세 잔류암의 제거가 이루어지지 않는다면 재발을 막는 데에 제한적인 치료방법일 수밖에 없다. 최근 자가 조혈모세포 이식과 더불어 IL-2로 체외에서 활성화한 조혈모세포 이식술 및 이식 후 지속적인 IL-2의 주입방법이 시행되고 있으며, 이로 인한 골수 회복의 지연, 발열 등 IL-2의 합병증에 대한 연구가 진행 중이다. 이에 저자 등은 다양한 고형암 및 혈액암 환자에게 자가 조혈모세포 이식과 더불어 IL-2로 활성화한 조혈모세포 이식술을 시행하여 그 경험을 보고하는 바이다. 방법: 1997년 3월부터 2000년 2월까지 3년간 아주대학교병원에서 고용량 항암 화학 요법 및 자가 조혈모세포 이식술을 시행받은 고형암 및 혈액암 환자 중 인터류킨-2로 활성화한 조혈모세포 이식술을 병행했던 환자 39명을 대상으로 하였으며, 그 중 10례는 절대 호중구 수치가 500/ul 이상 되었을 때, 나머지 29례는 그 이전상태에서 IL-2로 활성화한 조혈모세포를 추가로 이식하였다. 이 환자들의 이식과정 중 나타났던 발열, 피부발진 및 골수 생착과정의 지연여부 등을 후향적으로 조사하였다. 결과: 환자는 남자 10례, 여자 29례이었고, 중앙 연령은 39세(1~55세)이었으며, 활성화된 조혈모세포 이식 후 72시간 내에 발열이 있었던 경우를 WHO 기준으로 평가하여 3도 발열이 2례, 2도 발열이 23례, 1도 발열이 3례, 발열이 없었던 경우가 11례 이었다. 피부 발진은 이식을 위한 입원기간 동안 발생한 것을 WHO 기준으로 평가하여 3도 발진은 없었고, 2도 발진이 2례, 1도 발진이 3례 이었고, 나머지 34례는 피부에 이상소견을 보이지 않았다. 골수 생착의 지표인 백혈구 수치와 혈소판 수치는 절대 호중구 수치가 500/ul 이상이 되는 시기와 혈소판 수치가 20,000/ul 이상이 되는 시기가 골수 이식일로부터 각각 평균 11.7일(8~33일) 및 평균 16.1일(7~33일)이었으며, 이는 동일 기간 동안 아주대학교 병원에서 고용량 항암 화학 요법 및 IL-2가 포함되지 않은 자가 조혈모세포 이식술을 시행받은 72명의 무작위 추출군의 골수 생착속도가 각각 평균 11.8 일(p=0.102), 15.3 일(p=0.092)임을 비교해볼 때 IL-2로 활성화한 조혈모세포의 주입은 통계적으로 유의한 골수 생착속도 지연은 없었으며, 무작위 추출군 및 골수 생착 전 과 후의 IL-2 활성화 조혈모세포 이식군 간에 이식된 CD34+ 세포수의 통계학적인 차이는 없었다. 골수 생착이 이루어진 이후에 IL-2 활성화 조혈모세포 이식술을 시행한 경우는 골수 억압이 관찰되지 않았다. 결론: 고용량 항암 치료 및 자가 조혈모세포 이식술에 병행하는 IL-2 활성화 조혈모세포 이식술은 그 부작용으로서 발열, 피부발진 및 골수 생착의 지연 등이 있을 수 있으며, 자가 조혈모세포 이식 후 골수 생착이 이루어지지 않은 상태에서 시행한 IL-2 활성화 조혈모세포 이식술이 의미있는 골수 생착 지연을 초래하지 않는 것으로 나타났다. 본 연구는 IL-2 의 유용성과 합병증에 대한 후향적 연구로서 향후 보다 많은 증례를 통해서 IL-2 면역 요법의 효과에 대하여 비교 연구를 해야할 것으로 사료된다. Background: High dose chemotherapy(HDCT) with autologous peripheral blood stem cell transplantation(PBSCT) provides a higher degree of tumor debulking in various hematologic or non-hematologic malignancies, but it has the limitation in controlling micro-residual disease and in preventing relapse. Adoptive immunotherapy may conjoin to transplantation to prevent relapse after high dose chemotherapy. At present, many transplantation centers investigated the feasiblity of ex vivo activation of autologous PBSC by interleukin-2(IL-2), followed by the parenteral administration of IL-2 posttransplantation. Methodes: We now report the tolerability, feasibility and engraftment sequences using IL-2 ex vivo activated PBSC transplantation after autologous PBSC transplantation and continuous parenteral IL-2 administration posttransplantation in the 39 patients from March 1997 to February 2000. Among them 29 patients received IL-2 activated PBSC on day 3, 10 patients received after engraftment was achieved. Fever and skin rash were graded by WHO toxicity criteria. Results: There was no toxic death. 2 patients developed third degree fever, 23 patients second degree and 3 patients first degree but 11 patients did not develop fever. There was no patient who developed third degree skin rash, 2 patients second degree, 3 patients first degree but 34 patients did not develop any skin rash. The bone marrow engraftment was D+11.7 days(range 8~33 days) with neutrophil and D+16.1 days(range 7~33 days) with platelet. Comparing with the 72 patients who did not receive IL-2 in same duration and same center, bone marrow engraftment did not delayed(p=0.235, p=0.232, respectively). Among the control group, the post-engratment group and pre-engraftment group, there was no difference with transplanted CD 34+ cell count. Conclusions: High dose chemotherapy with autologous PBSC transplantation followed by IL-2 activated PBSC transplantation and continuous parenteral IL-2 administration posttransplatation is a tolerable and feasible treatment as an adoptive immunotherapy.
박준성,김진수 경희대학교 산학협력기술연구원 2005 산학협력기술연구논문집 Vol.11 No.4
Nanocrystalline ceria powders were prepared by hydrothermal treatment of cerium(IV) ammonium nitrate solution without a precipitating agent. A systematic investigation of the effect of hydrothermal temperature and reaction time on the physical properties of the product powders was carried out. When the hydrothermal temperature was increased, the product ceria powders exhibited larger crystallite size with higher yield. Increasing reaction time produced more crystalline ceria powders attributed to further hydrothermal reactions and structural rearrangement. The physical properties of ceria powders can be controlled by adjusting the hydrothermal conditions.
박준성,염미선,김은희,유리나,이윤정,고태성 대한소아신경학회 2014 대한소아신경학회지 Vol.22 No.4
Purpose: This study was performed to investigate the clinical presentations, diagnostic findings and prognosis of pediatric patients with the broad definition of “encephalitis”, that is inflammation of brain, in a single Korean tertiary center. Method: We retrospectively analyzed medical records of patients who had been diagnosed with encephalitis from January 2000 to July 2013 at the Asan Medical Center Children’s Hospital. We classified encephalitis in three categories of etiology which are infectious, para-infectious and primary inflammatory. The initial presentation, radiological and electroencephalographic findings, treatments and outcomes were reviewed. Results: During the 13-year study period, we found 199 pediatric cases of encephalitis.128 (64.3%), 50 (25.1%), and 21 (10.5%) cases were classified as infectious, para infectious and primary inflammatory encephalitis, respectively. They presented with fever (62.3%), altered mentality (51.3%), seizures (52.8%) and motor dysfunction (37.7%). Specific pathogens were proven in only 32 (25%) patients from 128 infectious encephalitis. Among 185 patients who had been followed up, 127 cases (68.6%) recovered without sequela and 50 cases (27%) with sequelae. Eight cases (4.3%), six with infectious encephalitis, one with acute disseminated encephalomyelitis and the other with Reye syndrome, expired. Conclusion: Infectious etiology is suggested in a great part of the pediatric encephalitis and additional efforts are needed to find specific etiologies of encephalitis in many cases. Considering the high mortality and morbidity of the pediatric encephalitis, prompt evaluations and appropriate treatment should be implemented. 목적: 다양한 임상증상을 보이며 심각한 합병증 또는 사망에 이를수 있는 소아뇌염의 원인을 알고 이에 따른 진단, 치료, 그 치료 경과를 알아보고자 하였다. 방법: 2000년 1월부터 2013년 7월까지 서울아산병원에 뇌염으로입원한 소아199명을 대상으로 후향적 검토를 통해 소아뇌염의 원인질환을 확인하고 원인질환에 따라 감염성, 부감염성, 일차 염증성 뇌염으로 분류하였으며 각각의 임상양상, 검사결과, 잠정진단에 따른 치료 및 질병경과를 조사하였다. 결과: 감염성 뇌염이 전체 뇌염의 64.3%로 가장 많았으며 특정 원인균이 동정되지 않은 경우가 75% 이었다. 부감염성 뇌염은 25.1%, 일차 염증성 뇌염은 10.5%로 확인되었다. 초기 증상으로 발열(62.3%), 경련발작(52.8%), 의식변화(51.3%), 운동 이상, 두통, 구토를보였으며, 뇌척수액 내 백혈구 증가는 72.6%에서, MRI 이상은 64%에서, EEG 이상은 76.6%에서 나타났다. 68.1%에서 완치되었으며 27% 에서 후유증을 남기고 4.3%는 사망하였다. 일차 염증성 뇌염에서 완치율이 낮고(P=0.032) 합병률이 높은 경향을 보였다(P=0.039). 경련증상(OR 4.17, P=0.007), 뇌파 이상소견(OR 3.37, P=0.037)이 나쁜 예후와 관련이 있었다. 결론: 발열, 운동기능 이상, 경련, 의식변화 등의 임상증상을 보이는환자에서 뇌염을 의심하고 최근 발달한 영상 및 혈청학적 검사를 포함하는 광범위한 검사와 잠정진단에 따른 즉각적인 치료가 필요하며합병증에 대하여 정신건강의학적 평가를 포함한 지속적인 추적관찰이 필요하다.
박준성 대한조선학회 2011 대한조선학회 학술대회자료집 Vol.2011 No.6
Although the estimation methods for an underwater vehicle performance were already presented, the verification of the methods has not been enough using experiments due to the intricacy of the experimental system. In this paper, free running model test on waterjet type underwater vehicle was carried out at the swimming pool using picture taken by continuous shooting mood. The vehicle' s trajectory and time series data of the vehicle speed, drift angle, heading angle and turning rate were obviously understood from the experiments.
朴埈成 誠信女子大學校 1986 硏究論文集 Vol.23 No.-
Labor relations traditionally have suffered from an identy crisis. In some schools they are taught as institutional economic courses or economic labor courses. Such courses rarely seem to address the managerial implications of labor relations. In ercent years the field of personnel and labor relations have experienced a resurgence of interest on part of managers. They are interested in how unions operate, how businesses become involved with labor unions, and how the negotiation and contract administraction process operates. thus, to managers, the understanding of the foundation of the trade unionism is necessary to see why the unions exists it does in its present form. This paper is based on the assumption that most managers need to have at least a basic understanding of the trade unionism as the theory of the labor movement. Trade unionism is divided into two major perspectives, as follows. Traditional uoionism is concerned with the ways in which unions are organized and seek to increase their security and power. Modern theories of unionism focus on the development of internal structure, administration, leadership, membership participation, and loyalty, all essential to the solidarity and unity which are the ultimate sources of the union`s power. Table-1 displays a brief summary of principal contribution to the trade unionism. Table-1 Summary of Trade Unionism _______________________________________________________________________________________________________________________ Perspective Researcher Union Organlzing Variables ________________________________________________________________________________________________________________________ Moral and ethical theories of Christian socialists, M. Mauris, moral and ethical values,beliefs. trade unionism C. Kingsley etc ________________________________________________________________________________________________________________________ Revolutiontradition of trade K. Mark, F. Engels, V.I. Lenin structure variables unionism etc _______________________________________________________________________________________________________________________ Psychological and defensive S.Perlman, A.S. Tannenbaum consciousness of opportunity, reaction of trade unionism etc scarcity, innovation _______________________________________________________________________________________________________________________ Economoc foundation and pur- S.&B. Webb structure(economic) variables pose of trade unionism _______________________________________________________________________________________________________________________ Democratic and political process N.W.Chamberlain,J.R.Comm- power relations of trade unionosm ons,J.S.Adams etc _______________________________________________________________________________________________________________________ Industrial Labor System J.T.Dunlop etc the rule, actors, ideology, _______________________________________________________________________________________________________________________ Oxford School/Pluralism H.A. Clegg, A. Flanders etc multivariates _______________________________________________________________________________________________________________________ Behavioral Perspectives M.E. Gordon, T.A. Kochan etc behavioral determinants _______________________________________________________________________________________________________________________ The distinction between the traditional and modern perspectives is identified as follows in Table-2. Table-2 Traditional & Modern Perspective in Unionism _______________________________________________________________________________________________________________________ Dimension Traditional Perspective Modern Perspective _______________________________________________________________________________________________________________________ Basic orientations Ideology-oriented System-oriented _______________________________________________________________________________________________________________________ Organizing behavior Labor movement Management movement _______________________________________________________________________________________________________________________ Goal-oriented Unidemensional Multidemensional _______________________________________________________________________________________________________________________ Strategic variables Ideology, Rules Environment, Strategy _______________________________________________________________________________________________________________________ pose of trade unionism