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박정섭,정승민,이시형,정기용,여현수,하유군,최유경,전찬용,김동우,박종형,Park, Jung-sup,Jung, Seung-min,Lee, Si-hyung,Jung, Ki-yong,Yeo, Hyun-soo,Hsia, Yu-chun,Choi, You-kyung,Jun, Chan-yong,Kim, Dong-woo,Park, Chong-hyeong 대한중풍순환신경학회 2006 대한중풍.순환신경학회지 Vol.7 No.1
Objectives : This study was prepared for investigating the clinical features of stroke patients. Methods : We retrospectively reviewed the medical records of 102 patients who were admitted to Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University with a diagnosis of stroke from Jan. 1, 2004 to Dec. 31, 2004. Results : Ischemic stroke(include TIA, 82.4%) was more common than hemorrhagic stroke(17.6%). The incidence in male was 41.2%, in female was 17.6% and the most prevalent age group is over-sixties. Cerebral infarction was most frequently noticed in lacunar-infarction and hemorrhage in putamen. Hypertention, the most preceding diseases, followed by diabetes mellitus and CVA. The rate of recurrence was 27.45%. Cerebral infarction and cerebral hemorrhage was much occurred after rising. The most patients visited the hospital within 24 Hours. The most common symptoms in admission time were motor weakness and speech disorder. The complication was mostly mental disorder. Conclusion : Our study on CVA patients was similar to previous studies from 1994 to 2003. In most cases, western and oriental treatment and medicine were given synthetically.
박정섭,이시형,임영남,정기용,전찬용,박종형,김동우,Park, Jung-Sup,Rhee, See-Hyung,Yim, Young-Nam,Jung, Ki-Young,Jun, Chan-Young,Park, Chong-Hyeong,Kim, Dong-Woo 대한한방내과학회 2005 大韓韓方內科學會誌 Vol.26 No.3
Objectives : This study was designed to evaluate the effects of oriental herb medicine therapy on a limited stage small ell lung cancer(SCLS) patient. Methods : The medical record of this case of SCLS was researched. The patient had been treated with oriental herb medicine for five months continuously in OPD. Clinical data was analyzed and the mass of small cell lung cancer before and after oriental herb medicine therapy was compared using X-ray and CT scan of the whole body in order to determine metastasis. Result : After 5 months of oriental herb medical treatment, most of symptoms disappeared or improved. The small cell lung cancer patially receeded and improvements were mainly seen in sputum, coughing, insomnia, diarrhea, and performance status. Conclusion : The study suggests that oriental herb medicine therapy effects the tumor size by causing remission and Improving health and relieving symptoms, and also positively effects the quality of life as a supportive or curative therapy for SCLC patients.
Streptozotocin 유발 당뇨 백서에 상엽 지각(桑葉 枳殼) 혼합물의 항당뇨 및 혈관탄성개선 효과
박정섭,박종형,전찬용,최유경,황귀서,김동우,Park, Jung-Sup,Park, Chong-Hyeong,Jun, Chan-Yong,Choi, You-Kyung,Hwang, Gwi-Seo,Kim, Dong-Woo 대한한방내과학회 2007 大韓韓方內科學會誌 Vol.28 No.3
Objectives : This study was designed to evaluate the anti-diabetes and vasoelasticity effects of Mori Folium and Aurantii Fructus in streptozotocin-induced type II diabetes mellitus model. Methods : The anti-diabetic effect of Mori Folium and Aurantii Fructus on rats induced with diabetes by streptozotocin was investigated through analyses of changes in body weight, blood glucose, urine volume of rats, viability of human umbilical vein endothelial cells(HUVECs), and elasticity of descending thoracic aorta in rats. The subjects in this study were divided into four groups(n=15): a normal group without any treatment (Con), a normal group with Mori Folium and Aurantii Fructus treatment(Con+P), a diabetes group induced by streptozotocin(STZ), and a Mori Folium and Aurantii Fructus treatment group under diabetes induced by streptozotocin(STZ+P). Rats were administered streptozotocin to induce diabetes. Results : The study showed that Mori Folium and Aurantii Fructus significantly reduced highly increased blood glucose levels(p<0.01) and prevented the diabetic rats from weight loss(p<0.01) and polyurea(p<0.05), Mori Folium and Aurantii Fructus also recovered decreased viability of HUVECs(p<0.01) and damaged elasticity of aorta induced by the streptozotocin (p<0.01). Conclusions: It was concluded from the results that Mori Folium and Aurantii Fructus have a distinct anti-diabetes effect and they also prevent damage of blood vessel induced by diabetes. resulting in prevention of cardiovascular diseases ascribed to diabetes.
삼봉강룡반어탕(三蓬薑龍半魚湯) 가(加) 하고초(夏枯草)와 加(가) 별갑(鱉甲)의 항암효과에 대한 비교연구
박정섭,정승민,임영남,고호연,한지완,김동우,Park, Jung-Sup,Jung, Seung-Min,Yim, Young-Nam,Ko, Ho-Yeun,Han, Ji-Wan,Kim, Dong-Woo 대한한방내과학회 2004 大韓韓方內科學會誌 Vol.25 No.4
In this piece of research, Prunellae spica is added to Sambonggangyongbaneotang for one group and Trionycis carapax is added to Sambonggangyongbaneotang for the other group. With these two different prescriptions, the degrees of tumor suppression are compared to develop a better prescription. SKH = Sambonggangyongbaneo-tang + Prunellae Spica SKB = Sambonggangyongbaneo-tang + Trionycis Carapax The results were as follows: 1. SKH and SKB demonstrated anti-tumor effects against tumor advancement of S-180 2. SKH and SKB showed on elevation of macrophage for tumor-bearing mice. 3. $100{\mu}g/ml,\;500{\mu}g/ml$ of SKH and $500{\mu}g/ml$ of SKB demonstrated a rise in alkaline phosphates of B-Lymphocyte in the spleen in tumor-bearing mice. Results support a role for both SKH and SKB for anti-tumor effects via endorsement of macrophage and encouragement of B-lymphocyte toward S-180.
박정섭(Jung-Sup Park) 한국정보보호학회 2015 정보보호학회논문지 Vol.25 No.6
최근 IT 산업에서 보안은 소프트웨어 개발 시 가장 중요하게 고려해야 할 요소로 자리 잡았다. 특히 자산을 보호하는 목적의 정보보호시스템의 보안성은 더욱 중요하다. 정보보호시스템의 보안성 평가시 공통평가기준(Common Criteria: CC)에서는 보안 구조(ADV_ARC) 패밀리 요구사항을 제공하여 평가대상의 보안성을 보장하도록 한다. 하지만, 체계적인 소프트웨어 보안 구조 설계 프로세스 없이 이러한 보증 요구사항을 일관되게 만족시키는 것이 다소 어려운 것이 현실이다. 본 논문에서는 BSIMM의 보안 프레임워크를 활용한 정보보호시스템의 보안 설계 방안을 제안한다. In the recent IT industry, security has established itself as the factor to be considered the most in the software development. It goes without saying that security is the critical factor for the development of information security products. In the evaluation of the information security products, the security is assured by the security architecture requirement (ADV_ARC). However, the Absence of the systematic software security architecture process makes it difficult to guarantee the security quality consistently even though they are evaluated based on common criteria. In this paper, we propose a way to ensure a consistent security quality applying the software security framework in BSIMM.
2-Aryl-3-(5-nitro-2-furyl) acrylamide류의 합성과 항균작용에 관한 연구
박정섭(Jung Sup Park) 대한약학회 1974 약학회지 Vol.18 No.4
Eighteen 2-aryl-3-(5-nitro-2-furyl) acrylamides were synthesized as antimicrobial agent, by the condensation of 2-(p-substituted phenyl)-3-(5-nitro-2-furyl) acryloyl chloride with amino component, such as sulfisoxazole, sulfamethoxypyridazine and sulfadimethoxine. All compounds showed fair bacteriostatic activity against Staphylococcus aureus 6538p, Bacillus subtilis, Escherichia coli, and Klebsiella pneumoniae. 2-(p-Hydroxyphenyl)- and 2-(p-acetoxyphenyl) compounds also showed antimicrobial activity against Saccharomyces cerevisiae 396 and Aspergillus oryzae.
7beta-[2-(치환 Benzylthio)Alkanamido]Cephalosporins의 합성 및 항균작용
박정섭(Jung Sup Park),김강열(Kang Yual Kim),유응걸(Eung Kul Ryu) 대한약학회 1988 약학회지 Vol.32 No.4
A series of substituted benzylthioalkanamidocephalosporins 3a-3p were synthesized and tested in vitro antibacterial activity. Of these new cephalosporins exhibited good antibacterial activity against Gram-positive bacteria whereas none of the compounds possessed the activity against Gram-negative bacteria at the concentration tested.
이시형,박정섭,여현수,최유경,전찬용,박종형,김동우,Rhee, See-Hyung,Park, Jung-Sup,Yeo, Hyun-Soo,Choi, You-Kyung,Jun, Chan-Yong,Park, Chong-Hyeong,Kim, Dong-Woo 대한한방내과학회 2006 大韓韓方內科學會誌 Vol.27 No.3
Objectives : This study investigated whether taking herbal medicine over the long-term had any side effects of liver damage. Methods : We checked LFT levels of the 58 admitted patients. Results : When we compared admission LFT levels with discharge LFT levels, we found the levels of AST, ALT and LDH had decreased. This test showed statistically significant decrease. When we compared admission LFT levels with discharge LFT levels, we found the increases of discharge LFT levels fell within the standard deviation. When we compared admission LFT levels with discharge LFT levels, we found the levels of LFT did not increase as much as two standard deviations. Conclusions : According to the above results, taking herbal medicine over a long-term did not have any side effects of drug-induced liver damage.
봉약침(蜂藥鍼)을 이용한 요추(腰椎) 추간판(椎間板) 탈출증(脫出症) 치료(治療)에 대한 증례보고
조태영,진성순,박정섭,여현수,임형호,이시형,Cho, Tae-Young,Jin, Sung-Soon,Park, Jung-Sup,Yeo, Hyun-Soo,Lim, Hyung-Ho,Rhee, See-Hyung 척추신경추나의학회 2006 척추신경추나의학회지 Vol.1 No.1
Objectives : This report was performed to evaluated the treatment of Bee venom acupuncture Therapy, acupuncture Therapy, Herbal medicaion and Moxibustion in herniation of inter-vertebral disc. Methods : We treated 1 case of herniation of inter-vertebral disc with Bee venom acupuncture Therapy, acupuncture Therapy, Herbal medicaion and Moxibustion. Results : After 12 days of Bee venom acupuncture Therapy, acupuncture Therapy, Herbal medicaion and Moxibustion, a remarkable improvement was made for herniation of inter-vertebral disc. The patient couldn't feel pain on walking. Conclusion : Bee venom acupuncture Therapy, acupuncture Therapy, Herbal medicaion and Moxibustion were effective in reducing the symptoms.
김학성(Hack-Seang Kim),박정섭(Jung-Sup Park),박해자(Hae-Ja Park),지형준(Hyung-Joon Chi) 한국생약학회 1980 생약학회지 Vol.11 No.1
A Study of the effects of the root components of Angelica gigas Nakai (Umbelliferae) on voluntary activity in mice has confirmed that there are: 1) MeOH soluble extract, MeOH insoluble extract, decursin and decursinol were antagonized against the voluntary activity in mice pretreated with a dose of caffeine natrium benzoate 30㎎/㎏. 2) MeOH insoluble extract, showed higher depressant effect than MeOH soluble extract. 3) The depressant activity of decursinol was significantly more highly effective than that of decursin.