저농도 혈중연과 혈장레닌활성도 및 혈압과의 관련성

박순우,김두희,Park, Soon-Woo,Kim, Doo-Hie 대한예방의학회 1991 예방의학회지 Vol.24 No.4

일상생활을 통한 연섭취로 인한 고혈압 발생 가능성 및 이때 연이 혈압에 영향을 미칠 수 있는 기전을 밝히기 위한 연구의 일환으로 환자 대조군 연구를 실시하였다. 대상자로서 울산 및 그 인근지역의 직업적 연폭로 과거력이 없는 남자 근로자 중 고혈압 환자 72명, 대조군 69명을 선택하였다. 혈중 연과 혈장레닌활성도(Plasma renin activity, PRA)를 측정하였으며 동시에 흡연유무, 음주유무, 고혈압 가족력 유무를 확인하고 body mass index(BMI), 혈청 소디움, 포타시움, 이온화 칼슘, 크레아티닌 및 총 콜레스테롤을 측정하였다. 고혈압군의 혈중 연농도는 $19.8{\pm}5.5{\mu}g/dl$로서 대조군의 $12.5{\pm}4.7{\mu}g/dl$에 비해 유의하게 높았고(p<0.01) 또한 혈중 연의 고혈압발생에 대한 교차비(odds ratio)가 1.38로서 역시 유의하였다(p<0.01). PRA나 In(PRA)가 고혈압군과 대조군 사이에 유의한 차이가 없었으나 고혈압군에서 혈중 연농도가 증가함에 따라 PRA도 어느정도 증가하는 양상을 보였고(p<0.1), In(PHA)를 종속변수로 하는 중회귀분석을 실시하였을 때 혈중 연농도(회귀계수 ; 0.037)가 10% 수준에서 유의하였다. 본 연구를 통해 볼 때, 지금까지 알려진 정상치 범위 이내의 혈중 연과 고혈압 발생간의 인과 관계에 대해 계속 연구해 볼 필요성을 느끼며 이때 PRA의 변화가 작용 기전의 일부에 관여할 가능성이 있을 것으로 추측된다. A case-control study was conducted to investigate the effect of low-level blood lead on the blood pressure. The plasma renin activity(PRA) was measured also to investigate one of the possible mechanisms by which lead nay play a role to influence on the blood pressure. Seventy-two hypertensive and sixty -nine control study subjects were selected from the workers who had no history of b-related lead exposure, in Ulsan city and it's vicinity, Korea. In addition to measuring blood lead levels and PRA, body mass index(BMI), hematocrit, serum sodium, potassium, creatinine, ionized calcium, and cholesterol were measured. Also, the habits of smoking, alcohol drinking and family history of hypertension were checked. The blood lead level of the hypertensive group was $19.8{\pm}5.5{\mu}g/dl$, which was significantly higher than that of the control group, $12.5{\pm}4.7{\mu}g/dl$(p<0.01). On multiple logistic regression analysis, the odds ratio of blood lead level on the occurence of high blood pressure was 1.38, also statistically significant (p<0.01). There was no significant differences between the hypertensive and the control group in the PRA or In (PRA), but there was a marginally significant linear relationship between blood lead and PRA in the hypertensive group(p<0.1). In conclusion, blood lead level which has been known to be within normal limits may be one of the possible risk factors of hypertension and PRA alteration by lead may act as one of the mechanisms.

청소년들의 또래 흡연율 추정에 대한 관련 요인

박순우,김종연,박정한,이상원,Park, Soon-Woo,Kim, Jong-Yeon,Park, Jung-Han,Lee, Sang-Won 대한예방의학회 2006 예방의학회지 Vol.39 No.3

Objectives: This study was conducted to examine the factors related to the perceived peer smoking prevalence for adolescents. Methods: A self-administrated questionnaire was administered to 352 students in a technical high school in Kangwon Province in May, 2002. The questions included in the questionnaire were concerned with the estimated number of smokers among ten students of the same grade in their school, the sociodemographic characteristics, the smoking-related behaviors and attitudes, and the smoking-related environments. All the students had their expiratory carbon monoxide level measured with EC50 Micro-Smokerlyzer? to verify their smoking status. Multiple regression analysis was applied for data analysis using Windows SPSS 11.5. Results: The former and current smokers overestimated the peer smoking prevalence. Multiple regression analysis for estimating the peer smoking prevalence for the male showed that the perceived smoking prevalence was higher in the female students than in the male students, higher in those students whose mothers had a higher educational level, who had smoked more frequently, who had more best friends smoking, and who had a higher actual smoking rate of the class. For estimating the peer smoking prevalence for the female, the perceived smoking prevalence was higher in the female students than in the male students, higher in those who smoked more frequently, whose five best friends smoked, who had higher actual smoking rate of the class, and who had smoking siblings. Conclusions: This study showed that a higher perceived peer smoking rate is related with their own smoking history and smoking frequency, the smoking related environment, and gender. Smoking prevention and smoking cessation programs need to focus on correcting the falsely perceived smoking prevalence.

설계기준 분석 방법에 의한 지역사회 청소년 흡연율 추정

박순우,이상원,박정한,윤연옥,이원기,김종연,Park, Soon-Woo,Lee, Sang-Won,Park, Jung Han,Yun, Yeon-Ok,Lee, Won-Kee,Kim, Jong-Yeon 대한예방의학회 2006 예방의학회지 Vol.39 No.4

Objectives: This study was conducted to estimate the unbiased smoking prevalence and its standard errors among adolescents in a large city in Korea, by design-based analysis. Methods: All the students in Daegu city were stratified by grade, gender and region, and then schools as primary sampling units (PSU) were selected by probability proportional to size (PPS) sampling. One or two classes were sampled randomly from each grade, from 5th grade in elementary schools to the 3rd grade in high schools. The students anonymously completed a standardized self-administered questionnaire from October to December 2004. The total number of respondents was 8,480 in the final analysis, excluding the third graders in the general high schools because of incomplete sampling. The sampling weight was calculated for each student after post-stratification adjustment, with adjustment being made for the missing cases. The data were analyzed with Stata 8.0 with consideration of PSU, weighting and the strata variables. Results: The smoking prevalence (%) and standard errors for male students from the fifth grade in elementary schools to the second grade in high schools were $0.93{\pm}0.47,\;1.83{\pm}0.74,\;3.16{\pm}1.00,\;5.12{\pm}1.02,\;10.86{\pm}1.13,\;15.63{\pm}2.44\;and\;17.96{\pm}2.67$, and those for the female students were $0.28{\pm}0.28,\;1.17{\pm}0.73,\;3.13{\pm}0.60,\;1.45{\pm}0.58,\;3.94{\pm}0.92,\;8.75{\pm}1.86\;and\;10.04{\pm}1.70$, sequentially. Conclusions: The smoking prevalence from this study was much higher than those from the other conventional studies conducted in Korea. The point estimates and standard errors from the design-based analysis were different from those of the model-based analysis. These findings suggest the importance of design-based analysis to estimate unbiased prevalence and standard errors in complex survey data and this method is recommended to apply to future surveys for determining the smoking prevalence for specific population.

정신지체아 두발 중 중금속 함량 II - 카드뮴 및 아연과의 관련성 -

박순우,이종영,김두희,Park, Soon-Woo,Lee, Jong-Young,Kim, Doo-Hie 대한예방의학회 1989 Journal of Preventive Medicine and Public Health Vol.22 No.2

정신지체와 인체내 카드뮴 함량과의 관련성을 보기 위해 정신지체아 297명(가정이 있는 아동이 다니는 특수학교 1개교의 132명과 고아로 구성된 특수학교 1개교의 165명)을 대상으로 두발중 카드뮴 및 아연함량을 측정하였으며 학업성적이 중위권 이상인 일반 국민학교 학생 117명을 대조군으로 하여 비교해 보았다. 시료의 분석은 원자흡광광도계를 이용하였다. 두발 중 카드뮴 함량의 연령에 따른 차이는 없었으며 아연은 대조군 남자의 경우 연령 증가에 비례하였다. 가정이 있는 정신지체아의 경우 카드뮴 함량이 남녀 각각 $0.64{\pm}0.24ppm,\;0.66{\pm}0.18ppm$, 가정이 없는 정신지체아(고아군)의 경우 남녀 각각 $0.71{\pm}0.19ppm,\;0.65{\pm}0.15ppm$ 으로써 대조군 (남;$0.45{\pm}0.15ppm$, 여:$0.49{\pm}0.16ppm$)에 비해 유의한 차이가 있었다. 그러나 아연의 경우 유의한 차이는 없었다. 정신지체의 정도별로 보았을때 고아인 경우 남녀 모두 카드뮴 함량이 지체정도가 심할수록 높았으나 가정이 있는 지체아의 경우는 그러한 차이가 없었다. 다만 선천성 질환인 Down증후군은 남녀 모두 대조군과 카드뮴함량의 차이가 없었다. 자폐증이 있는 경우 아연의 함량이 특이적으로 낮았다. 본 연구의 결과에서 카드뮴이 정신지체에 어느 정도의 영향을 끼칠 것으로 추측되나 더욱 연구를 계속해 보아야 하겠다. The relationship between cadmium level and mental retardation was investigated. The 297 subjects with mental retardation were drawn from two schools providing special educational services, one, consisted of children living in an orphan home, another, children with parents. The 117 control subjects were drawn from whom had got average or above average academic achivement in a general elementary school. Hair sample was taken from the nape of the neck and the cadmium and zinc analysis were carried out on an atomic absorption spectrophotometer (IL 551). Children in the retarded group had significantly higher cadmium levels compared with control but not in zinc levels. There was no relationship between metal concentrations and age except control male group, which showed significant positive linear relationship in zinc, and there was no difference between sex in both metal except the male orphan group in cadmium. In the orphan group, there was relationship between severity of retardation and cadmium concentration in both sex but not in retarded children with parents. No difference in cadmium levels between the group with Down's syndrome, one of causes of mental retardation, and the control group suggested the cadmium as a possible cause of mental retardation. In the case of accompanying autism, zinc level was significantly lower than that of other accompanying diseases. Although not establishing an etiologic relationship, findings of this study suggest that there are some influeces of cadmium on mental retardation, and call for a continuing study.

고려전기 정부의 한인(漢人)인식과 내투(來投) 한인들의 행적

박순우(Park, Soon-woo) 한국역사연구회 2012 역사와 현실 Vol.- No.84

So far, studies of the Chinese people who immigrated to the Korean peninsula during the Goryeo dynasty period rather concentrated upon determining their overall number, or the governmental posts they received after immigration. Based upon such data, previous studies concluded that Goryeo, out of sincere respect of advanced Chinese institutions, actively invited these Chinese figures to Goryeo with the objective to refine its own governmental system, and the Chinese immigrants were treated more fabulously than any other Goryeo officials. Yet such conclusion needs to be revised in certain points. According to the analysis attempted in this article, the situation before the reign of King Munjong, and the situation which unfolded in the following era, were fairly different. Before King Munjong’s reign, it is true that the Chinese immigrants-turned-Goryeo officials received rather high ranks, yet in the wake of certain political strifes and rather heightened animosity from local Goryeo officials, their career and their status did not last very long. Then, since King Mujong’s reign, things started to change. Most of the Chinese immigrants entered the Goryeo government only after passing the national examination, and received low-rank positions as their first assignments, just like any other Goryeo officials did. Animosity toward Chinese immigrants was considerably weakened compared to before, and a much warmer environment for them was established, partially thanks to the Goryeo people’s cultural achievements accumulated at that point. Also, some of the descendants of these Chinese immigrants are confirmed to have served the Goryeo government as well. It does not seem like they were elevated to powerful families, but at least we can see that they were being integrated into the Goryeo society. Such integration was made possible not by the Goryeo government’s urging or the accomplishments of limited number of individuals, but by the Chinese immigrants’ own collective efforts. And their activities would surely have changed the Goryeo people’s view of the people from foreign countries.

일부 농촌지역 농업조사자들의 건강진단 수검 실태

박순우(Soon-Woo Park) 한국농촌의학 지역보건학회 1997 농촌의학·지역보건 Vol.21 No.1

노인생활시설 종사자의 재교육 활성화에 관한 연구

박순우(Soon Woo Park),정성배(Seong Bae Jeong) 한국노인복지학회 2006 노인복지연구 Vol.0 No.34

라마찬드란 플롯 관점에서 바라본 단백질 구조의 정적 및 동적 특성

박순우(Soon Woo Park),이병호(Byung Ho Lee),송승훈(Seung Hun Song),김문기(Moon Ki Kim) 대한기계학회 2022 대한기계학회 춘추학술대회 Vol.2022 No.11

농촌지역 청소년의 건강행태

박순우(Soon-Woo Park) 한국농촌의학 지역보건학회 2009 농촌의학·지역보건 Vol.34 No.2

본 연구는 농촌지역 청소년들의 건강행태를 도시지역 청소년들과 비교하기 위해 2005년에 실시한 전국청소년건강행태 온라인 조사 자료를 이용하여 분석하였다. 그 결과 흡연경험률, 중학교 입학전 흡연경험률, 음주빈도, 음주후 위험행동 경험률, 점심 및 저녁 결식, 과일 및 우유 섭취, 칫솔질 횟수, 구강질환 증상 경험, 구강 진료 경험, 구강 에방진료. 안전 및 위생의식 등의 행태에서 도시지역 청소년에 비해 바람직하지 못 한 결과를 보였다. 이러한 결과가 지역규모에 따른 차이인지 혹은 도농간의 사회경제적 수준의 격차와 관련이 있는지에 대하여 향후 추가적인 연구가 필요하다. 본 조사 결과를 통해 청소년 건강행태 개선을 위한 건강증진사업은 농촌 청소년을 대상으로 우선적으로 수행하여야 할 당위성을 확인하였다고 할 수 있다. Objectives: The aim of this study was to compare health related behaviors among adolescents in the rural area with those in the urban area in Korea. Methods: The data source was the Korea Youth Risk Behavior Web-based Survey in 2005. With two stage cluster sampling, a total of 58,224 sample was selected from 799 middle and high schools nationwide. The area was classified into county area, small to medium city, and large city, and then the county area was considered as a rural area. Data was analyzed with STATA 9.0 using the method of complex survey data analysis considering sampling weight, strata, and primary sampling unit. Results: The prevalence of health related behaviors among adolescents in the rural area was higher than the city area as following health behaviors: smoking behaviors of smoking experience, smoking experience before entrance to middle school; drinking behaviors of frequent drinking, high risk behaviors with drinking; dietary behaviors of omitting of lunch or dinner, less intake of fruits or milk, more intake of cooky; oral hygiene of less tooth brushing, less preventive oral care, more oral symptoms and less dentist visit; safety behaviors of less wearing of safety belt or protective device; general hygiene of less hand washing before meal or after visiting rest room. Conclusions: The health behaviors among adolescents in the rural area were generally poorer than the city area. The results showed national health program for adolescents should be conducted primarily for those in rural areas. Further study is needed to explore the factors related with the discrepancy of health behaviors between the rural and urban area.

영국복지개혁의 사회투자전략에 관한 연구

박순우 ( Soon Woo Park ),최영 ( Young Choi ) 한국사회복지정책학회 2007 사회복지정책 Vol.30 No.-