도시녹지 유형에 따른 휘발성유기화합물 농도 특성

조예슬(Yeseul Jo),박수진(Sujin Park),노관평(Gwan Pyeong Roh) 한국환경보건학회 2018 한국환경보건학회지 Vol.44 No.4

Objectives: The occurrence characteristics of BTEXS and phytoncides were investigated by type of urban forest. Methods: Four types of urban green space (Hongneung Forest, Mt. Chunjang, residential park, and traffic island) and Gwangneung Forest were selected. Monitoring of phytoncides and BTEXS was conducted considering the activity times of urban residents (five times per day) using a Tenax TA tube and suction pump in June 2017 (one day). Results: Phytoncide concentrations were ranked as Gwangneung Forest>Hongneung Forest>Mt. Cheonjang> traffic island>residential park. Relatively high concentrations of phytoncides were also identified in the urban forest. There was no significant difference between Gwangneung Forest and the urban forest. BTEXS concentrations were ranked as traffic island>residential park>Hongneung Forest>Gwangneung Forest>Mt. Cheonjang. Traffic island and residential park showed high levels of BTEXS depending on the inflow of vehicles. The difference in concentration by time was significant for the traffic island in particular. Pollutant levels in Hongneung Forest were as low as in Gwangneung Forest. Conclusion: The concentrations of phytoncides and BTEXS were different by types of urban green space, and the potential for health and hygiene of urban forests were able to be investigated. This study is expected to provide as basic data for the creation of urban forest spaces in the future.

Ti-capping층이 NiSi의 열적안정성에 미치는 영향

박수진,이근우,김주연,전형탁,배규식,Park, Soo-Jin,Lee, Keun-Woo,Kim, Ju-Youn,Jun, Hyung-Tak,Bae, Kyoo-Sik 한국재료학회 2003 한국재료학회지 Vol.13 No.7

Ni and Ti films were deposited by the thermal evaporator, and then annealed in the N$_2$ ambient at 300-80$0^{\circ}C$ in a RTA(rapid thermal annealing) system. Four point probe, AEM, FESEM, AES, and XPS were used to study the effects of Ti-capping layers on the thermal stability of NiSi thin films. The Ti-capped NiSi was stable up to $700^{\circ}C$ for 100 sec. RTA, while the uncapped NiSi layers showed high sheet resistance after $600^{\circ}C$. These results were due to that the Ni in-diffusion and Si out-diffusion were retarded by the capping layer, resulting in the suppression of the formation of NiSi$_2$and Si grains at the surface.

학술발표회 초록 ( 열역학 (Ⅱ) ) : Butane - Methanol , Butane - Ethanol 계의 90℃ 등온 기액상평형과 과잉 몰엔탈피

박수진,박소진 ( Soo Jin Park,So Jin Park ) 한국화학공학회 1994 춘계학술발표회 Vol.- No.-

치면열구전색재의 충전량에 따른 미세누출의 비교연구

박수진,정태성,김신,Park, Soo-Jin,Jung, Tae-Sung,Kim, Shin 대한소아치과학회 2003 大韓小兒齒科學會誌 Vol.30 No.2

본 연구는 치면열구전색재의 충전량이 미세누출에 미치는 영향을 비교분석할 목적으로 실시되었다. 6개의 군으로 나누어 각각 다른 충전량, 치면 전처리, 충전재를 적용하여 미세누출 양상을 비교하였다. 60개의 제 3대구치를 3개의 군으로 나누어 각 군당 20개씩 시편을 구성하였다. 각 치아는 교합면을 두 부분으로 나누어 한 부위는 충전재의 폭이 1mm이하가 되도록 충전하고(1, 3, 5군), 나머지 한 부위는 2mm이상 되도록 충전을 하였다(2, 4, 6군). 1, 2군은 산처리후 Helioseal F로 치면열구전색을 실시하였고, 3, 4군은 산처리후 상아질 접착제로 치면 전처리한 후 Helioseal F로, 5, 6군은 유동성 복합레진인 Tetric Flow로 치면 열구전색을 실시하였다. 500회의 열순환 및 색소침투 후, 미세누출도를 관찰하고 비교분석하여 다음과 같은 결론을 얻었다. 1. 동일한 충전폭을 적용하였을 경우, 미세누출도는 5군<3군<1군과 6군<4군<2군의 순으로 나타났으나 유의한 차이는 아니었다(p>0.05). 2. 동일한 재료와 치면처리를 하되, 충전폭만을 달리한 군들, 즉 1군과 크군, 3군과 4군, 5군과 6군간의 미세누출도에서는 유의한 차이를 보였다(p<0.05). 3. 미세누출은 전색재의 물성, 상아질 접착제 전처리 여부 보다 전색재의 충전량에 더 많은 영향을 받았다. With the purpose of evaluating the effect of ailing amount of pit and assure sealants on the microleakage, 6 groups of specimens with different filling amount, filling materials and surface pretreatment were investigated. Sixty permanent third molars were divided into three groups. The occlusal surface of each tooth was divided into two parts; the filing width of one part was below 1mm (group1, 3, 5), and in the other part more than 2mm (group 2, 4, 6) Group 1 and 2: Helioseal F was applied directly to etched enamel; Group 3 and 4: Helioseal F was applied to etched and scotchbond Multi-purpose plus pre-treated enamel; Group 5 and 6: Tetric Flow was applied. After 500 times thermocycling and dye infiltration, we evaulated the microleakage. The results were as follows; 1. The mean microleakage score at each width were increased in the following order;group 5<3<1, and group 6<4<2. 2. In comparing the groups with same material and surface pretreatment but with different filling width (group 1 versus 2, 3 versus 4, 5 versus 6), the microleakage scores were significantly different. 3 The microleage was affected by filling amount of pit and assure sealants than Oiling materials and dentin bonding agent pretreatment.

민간투자사업 활성화를 위한 제언

박수진,Park, Su-Jin 한국건설관리학회 2019 한국건설관리학회 논문집 Vol.20 No.4

최소 효과 용량을 정하는 축차 검정법

박수진,김동재,Park, Su-Jin,Kim, Dong-Jae 한국통계학회 2009 응용통계연구 Vol.22 No.5

신약 개발 연구 또는 임상시험에서 개발된 약이 0용량 대조군과 비교해 유의한 효과 차이가 있어 신체에 반응할 수 있는 최소 복용량을 결정하는데, 이 최소 복용량을 최소 효과 용량(Minimum Effective Dose; MED)이라 한다. 이 논문에서는 최소 효과 용량을 확인하기 위하여 업데이티드 대조군을 이용한 모수적 축차 검정법을 제안하였다. 또한 모의 실험을 통하여 기존의 검정법과 제안한 검정법의 실험유의수준(experimental significance level)과 검정력(power)을 비교하였다. In new drug development studies or clinical trials, zero-dose control is needed in general to determine the lowest dose level for a new drug which can act with our bodies. When the lowest dose level compared with zero-dose control has significant difference in effect, it is referred as minimum effective dose(MED). We propose, in this paper, parametric sequential test using updated control to identify the minimum effective dose(MED) level. Monte Carlo Simulation is adapted to examine the power and experimental significance levels of the proposed method with other methods.

Twin Block을 이용한 II급 부정교합의 치료증례

박수진,장기택,김종철,Park, Soo-Jin,Jang, Ki-Taeg,Kim, Chong-Chul 대한소아치과학회 1998 大韓小兒齒科學會誌 Vol.25 No.1

Twin Blocks are simple bite-blocks that effectively modify the occlusal inclined plane to induce favorably directed occlusal forces by causing a functional mandibular displacement. These devices use upper and lower bite-blocks that engage on occlusal inclined planes. Twin Blocks use the forces of occlusion as the functional mechanism to correct the malocclusion. To get an excellent result in the treatment by using the Twin Block appliances, proper case selection must be needed. Twin Block treatment is performed in two stages. Twin Blocks are used in the active phase to correct the anteroposterior relationship and establish the correct vertical dimension. Once this phase is accomplished, the Twin Blocks are replaced with an upper Hawley type of appliance with an anterior inclined plane, which is then used to support the corrected position as the posterior teeth settle fully into occlusion. The Twin Block is the most comfortable, the most esthetic ane the most efficient of all the functional appliances. Twin Blocks have many advantages compared to other functional appliances. Patients can wear Twin Blocks 24 hours per day and can eat comfortably with the appliances in place. From the moment Twin Blocks are fitted, the appearance is noticeably improved. There is less interference with normal function. Integration with conventional fixed appliances is simpler than with any other functional appliance. Twin Blocks allow independent control of upper and lower arch width. Appliance design is easily modified for transverse and sigittal arch development. The authors treated Class II malocclusion with Twin Blocks. and the results as follows; 1. Rapid profile improvement was achieved in 2-3 months. 2. There was excellent patient cooperation. 3. Severe overjet and overbite were reduced. 4. Class II molar relationship was changed to Class I.

강원도 기후변화 적응대책 세부시행계획 수립 현황

박수진,한대건,Park, Su-Jin,Han, Dae-Geon 한국수자원학회 2020 물과 미래(한국수자원학회지) Vol.53 No.9

시계열 모형과 기계학습 모형을 이용한 풍력 발전량 예측 연구

박수진,이진영,김삼용,Park, Sujin,Lee, Jin-Young,Kim, Sahm 한국통계학회 2021 응용통계연구 Vol.34 No.5

Wind energy is one of the rapidly developing renewable energies which is being developed and invested in response to climate change. As renewable energy policies and power plant installations are promoted, the supply of wind power in Korea is gradually expanding and attempts to accurately predict demand are expanding. In this paper, the ARIMA and ARIMAX models which are Time series techniques and the SVR, Random Forest and XGBoost models which are machine learning models were compared and analyzed to predict wind power generation in the Jeonnam and Gyeongbuk regions. Mean absolute error (MAE) and mean absolute percentage error (MAPE) were used as indicators to compare the predicted results of the model. After subtracting the hourly raw data from January 1, 2018 to October 24, 2020, the model was trained to predict wind power generation for 168 hours from October 25, 2020 to October 31, 2020. As a result of comparing the predictive power of the models, the Random Forest and XGBoost models showed the best performance in the order of Jeonnam and Gyeongbuk. In future research, we will try not only machine learning models but also forecasting wind power generation based on data mining techniques that have been actively researched recently. 빠르게 발전하고 있는 재생에너지 중 하나인 풍력에너지는 기후변화 대응에 맞추어 개발 및 투자가 이루어지고있다. 신재생에너지 정책과 발전소 설치가 추진됨에 따라 국내 풍력 보급이 점차 확대되어 수요를 정확히 예측하기 위한 시도들이 확대되고 있다. 본 논문에서는 전남지역과 경북지역의 풍력 발전량 예측을 위하여 시계열 기법인 ARIMA, ARIMAX 모형과 기계학습 모형인 SVR, Random Forest, XGBoost 모형들을 비교 분석하였다. 모형의 예측 결과를 비교하기 위한 지표로서 mean absolute error (MAE)와 mean absolute percentage error (MAPE)를 사용하였다. 2018년 1월 1일부터 2020년 10월 24일까지의 시간별 원 데이터를 차분한 후 모형을 훈련시켜 2020년 10월 25일부터 2020년 10월 31일까지의 168시간에 대한 풍력 발전량을 예측하였다. 모형의 예측력 비교 결과, Random Forest와 XGBoost 모형이 전남지역, 경북지역 순으로 가장 우수한 성능을 보였다. 향후 연구에서는 기계학습뿐 아니라 최근 활발한 연구가 이루어지는 데이터 마이닝 기법 기반의 풍력 발전량 예측을 시도할 것이다.

A Case of Kabuki Syndrome Confirmed by Genetic Analysis: A Novel Frameshift Mutation in the KMT2D Gene

박수진,안문배,장우리,조원경,채효진,김명신,서병규,Park, Su Jin,Ahn, Moon Bae,Jang, Woori,Cho, Won Kyung,Chae, Hyo Jin,Kim, Myung Shin,Suh, Byung Kyu The Korean Society of Inherited Metabolic Disease 2017 대한유전성대사질환학회지 Vol.17 No.3

가부키 증후군(Kabuki syndrome)은 특징적인 얼굴(아치형의 넓은 눈썹, 낮은 코끝, 큰 귓바퀴, 아래 외측 안검 외전), 골격계 이상, 출생 후 성장 지연, 그리고 경도의 정신 지체를 특징으로 나타내는 선천성 이상 질환이다. 또한, 선천성 심장기형, 비뇨생식기 기형, 구개구순열을 포함한 위장관 기형, 안검 하수 등의 증상이 동반되기도 한다. 감염과 면역질환, 경련, 내분비 문제, 청력 손실이 나타날 수 있다. 가부키 증후군의 대부분은 12번 염색체의 장완에 위치한 KMT2D 유전자의 돌연변이에 의해 발병된다. KMT2D 유전자의 돌연변이로 생성된 비정상적인 KMT2D 단백질로 인해 신체의 여러 장기와 조직의 특정 유전자의 활성이 정상적으로 이뤄지지 못하여, 결과적으로 가부키 증후군의 특징적인 외형과 기능장애가 나타난다. 출생시 선천성 심장 기형, 갑상선 기능 저하 및 일과성 저혈당 과거력이 있던 환아가 만 4세경 성장 지연, 아치형 눈썹, 낮은 코끝, 아래 외측 안검 외전, 큰 귓바퀴 등의 얼굴 생김새를 보여 시행한 분자유전학적 검사에서 KMT2D의 exon 15에서 새로운 frameshift mutation이 발견되어 증례를 보고하는 바이다. 가부키 증후군은 성장 지연 뿐 아니라, 발달 장애 및 행동 장애, 사춘기 여아의 경우 조기 가슴 발육을 포함한 내분비적 문제, 사시, 안검하수 등의 안과적 문제, 만성 중이염, 청력 손실, 감염, 경련 등 다양한 증상을 나타낼 수 있기 때문에 조기에 질환을 진단하고, 임상증상에 따라 적절한 중재를 할 수 있도록, 정기적으로 신장, 몸무게, 머리둘레, 발달상태, 청각과 시각상태를 확인하는 것이 중요하다. 따라서 여러 장기의 선천 기형을 보이는 환아의 경우, 임상의는 출생 당시에는 두드러지지 않을 수 있는 특징적인 얼굴 생김새, 성장 지연, 정신 지체 등의 이상에 대해 유의하여야 한다. 분자유전학적 검사는 임상적으로 가부키 증후군이 의심되는 환아를 조기에 진단할 수 유용한 방법이며, 앞으로도 가부키 증후군과 연관된 유전자 변이에 대한 연구가 더욱 필요할 것으로 사료된다. Kabuki syndrome is a rare congenital disorder that causes multiple birth defects and mental retardation. Mutation of the lysine methyltransferase 2D (KMT2D) gene is the primary cause of Kabuki syndrome. We report a 4-year-old Korean girl diagnosed with Kabuki syndrome based on distinctive facial features (eversion of the lower lateral eyelid, arched eyebrows, depressed nasal tip, prominent ears), skeletal anomalies, short stature, and molecular analysis, which revealed a novel frameshift mutation in the KMT2D gene. A 4-year-old patient had a past history of congenital cardiac malformations (coarctation of the aorta, ventricular septal defect, atrial septal defect, patent ductus arteriosus), subclinical hypothyroidism and dysmorphic features at birth including webbed neck, short fingers, high arched palate, micrognathia and horseshoe kidney. She showed unique facial features such as a long palpebral fissure, long eyelashes, arched eyebrows with sparseness of the lateral third, broad nasal root, anteverted ears, and small mouth. Her facial features suggested Kabuki syndrome, and genetic analysis discovered a novel heterozygous frameshift mutation (c.4379dup, p.Leu1461Thrfs*30) in exon 15 of the KMT2D gene. The diagnosis of our 4-year-old patient was made through thorough physical examination and history taking, and genetic testing. It is challenging to diagnose patients with Kabuki syndrome at birth, since the characteristic facial features are expressed gradually during growth. Clinical suspicion aroused by regular follow-ups may lead to earlier diagnosis and interventions.