표적세포의 Nitric oxide 합성이 LAK 세포의 세포독성에 대한 예민도에 미치는 영향

박성일,박주형,이치국,김신재,최보금,곽재용,임창열,Park, Sung Il,Park, Ju Hyung,Lee, Chi Kug,Kim, Shin Chae,Choi, Bo Geum,Kwak, Jae Yong,Yim, Chang Yeol 대한면역학회 2001 Immune Network Vol.1 No.2

Background: Nitric oxide (NO), a cytotoxic molecule is produced in various tissues including tumor cells during interleukin-2 (IL-2) therapy . Lymphokine-activated killer (LAK) cells are induced during IL-2 therapy, and have cytotoxic activity against tumor cells. The current study investigated the effects of NO synthesized in target cells or exposure of target cells to NO on the sensitivity of target cells to LAK cell cytotoxicity. Methods: Cytotoxicity was measured using 4 h chromium release assays. LAK cells which were induced by a 4 day incubation of BALB/c mouse splenocytes with IL-2 (6,000 IU/mL) were employed as effector cells. RD-995 skin tumor cells originated from a C3H/HeN mouse were employed as target cells. NO synthesis in target cells was induced by a 24 h incubation of RD-995 cells with $IFN{\gamma}$ (25 U/mL), TNF (50 U/mL) and IL-1 (20 U/mL). S-nitrosyl acetylpenicillamine (SNAP), an NO donor, was used to expose target cells to NO. $N^G$-monomethyl-L-arginine (MLA) and carboxy-PTIO were added during cytotoxicity assays to inhibit NO synthesis, and to scavenge NO produced by target cells, respectively. Results: Sensitivity of NO-producing RD-995 cells to LAK cell cytotoxicity was decreased by addition of MLA and carboxy-PTIO during cytotoxicity assays. However, the two reagents had no effect on the sensitivity of non-NO-producing RD-995 cells. Pretreatment of RD-995 target cells with SNAP increased the sensitivity in comparison with untreated cells. Conclusions: Sensitivity of target cells to LAK cell cytotoxicity is increased by target cell NO synthesis or exposure to NO. Further studies are needed to evaluate whether these in vitro results have relevance to in vivo phenomena.

내장형 트리플(DCS, PCS, UPCS) 칩 안테나 설계 및 제작

박성일,박성하,고영혁,Park, Seong-Il,Park, Sung-Ha,Ko, Young-Hyuk 한국정보통신학회 2009 한국정보통신학회논문지 Vol.13 No.7

본 논문에서는 이동통신용 단말기 PCB Layout 위에 내장형 칩 안테나를 직접 설계하여 DCS(1.71${\sim}$1.88GHz) 대역, PCS(1.75${\sim}$1.87GHz) 대역 및 UPCS(1.85${\sim}$1.99GHz)대역에서 공통으로 사용할 수 있는 이동통신용 트리플밴드 칩 안테나를 설계하였다. 안테나의 특성 해석을 위해서 상용 고주파 시뮬레이션인 HFSS를 이용하였다. 트리플 광대역 특성은 1.71GHz${\sim}$1.99GHz의 대역에서 동작하는 설계된 안테나의 측정된 대역폭(V.S.W.R<2.0)을 실현시켰다. 이 안테나의 크기는 19mm${\times}$4mm${\times}$1.6mm로 설계하여 소형화시켰으며, 칩 안테나의 단점인 좁은 대역폭을 크게 개선시켰다. 그리고 실험 측정 결과들은 시뮬레이션 결과들과 매우 유사함을 보여 주었다. In this paper, triple band mobile chip antenna for DCS(1.71${\sim}$1.88GHz) / PCS(1.75${\sim}$1.87GHz) / UPCS(1.8S${\sim}$1.99GHz) on PCB Layout is designed. To analyze the characteristics of the designed antenna, we used commerical simulation tool(HFSS). Triple and wide band characteristic could be realized the measured bandwidth(V.S.W.R<2.0) of the designed antenna operated in 1.71GHz${\sim}$1.99GHz. The size of the designed antenna is about 19mm${\times}$4mm${\times}$1.6mm, narrow bandwidth which is a defect of chip antenna is improved. And its experimental results were a good agreement with simulation performance.

QMSA 구조를 활용한 내장형 트리플 칩 안테나 개발

박성일,Park, Sung-Il 한국전자통신학회 2013 한국전자통신학회 논문지 Vol.8 No.10

본 논문에서는 이동통신용 단말기 PCB Layout 위에 내장형 칩 안테나를 직접 설계하여 DCS(1.71~1.88GHz) 대역, PCS(1.75~1.87GHz) 대역 및 UPCS(1.85~1.99GHz)대역에서 공통으로 사용할 수 있는 이동통신용 트리플밴드 칩 안테나를 설계하였다. 안테나의 특성 해석을 위해서 Single, Dual, Triple Band 안테나를 설계 및 측정하였다. 설계된 안테나들은 제작하여 LTK(Laird Technologies Korea)에서 네트워크 분석기에 의해서 측정되었다. 트리플 광대역 특성은 1.71GHz~1.99GHz의 대역에서 동작하는 설계된 안테나의 측정된 대역폭(V.S.W.R<2.0)을 실현시켰다. 이 안테나의 크기는 $19mm{\times}4mm{\times}1.6mm$으로 설계하여 매우 소형화시켰으며, 칩 안테나의 단점인 좁은 대역폭을 크게 개선시켰다. 그리고 실험 측정 성능들은 시뮬레이션 성능들과 매우 유사함을 보여 주었다. In this paper, triple band mobile chip antenna for DCS(1.71~1.88GHz) / PCS(1.75~1.87GHz) / UPCS(1.85~1.99GHz) on PCB Layout is designed. To analyze the characteristics of the designed antenna, we designed and measured Single, Dual, Triple Band antenna. The designed antenna was fabricated and measured using vector network analyzer in LTK(Laird Technologies Korea). Triple and wide band characteristic could be realized the measured bandwidth(V.S.W.R<2.0) of designed antenna operated in the band of 1.71GHz~1.99GHz. This antenna has a small size of about $19mm{\times}4mm{\times}1.6mm$, narrow bandwidth which is a defect of chip antenna is improved. And its experimental results were a good agreement with simulation performance.

WLAN Dual Band Dipole Antenna with Parasitic Elements and Reflector for High Gain Operation

박성일,정진우,Park, Sung-Il,Jung, Jin-Woo Korea Institute of Electronic Communication Scienc 2018 한국전자통신학회 논문지 Vol.13 No.2

A WLAN dual band dipole antenna with parasitic elements and a reflector is presented for high gain operation. The parasitic elements are used for practical application and high gain operation of the radiation pattern at the WLAN dual band. The proposed antenna consists of three layers, and has dimensions of $74mm{\times}40 mm{\times}31.4mm$. From the experimental results, the achieved impedance bandwidths were 1035 MHz (2.031-3.066 GHz) and 1119 MHz (5.008-6.127 GHz), respectively. The measured maximum gain at each WLAN band was 6.69 dBi and 7.81 dBi, respectively. 고 이득 방사 특성을 위한 기생 및 반사 소자를 갖는 WLAN 이중 대역 다이폴 안테나를 제안하였다. WLAN 이중 대역에서 실용적인 고 이득 방사 특성을 위해 기생 소자를 사용하였다. 제안된 안테나는 3개의 층으로 구현되었으며, 전체 체적은 $74mm{\times}40 mm{\times}31.4mm$ 이다. 측정 결과 제안된 안테나의 임피던스 대역폭은 1035 MHz (2.031-3.066 GHz)와 1119 MHz (5.008-6.127 GHz)를 만족하였으며, 각 WLAN 대역에서 최대 이득은 6.69 dBi와 7.81 dBi로 측정되었다.

치주 치료 후 적용된 상아질 지각과민 억제제의 임상 효과에 대한 연구

박성일,정진형,임성빈,홍기석,Park, Sung-Il,Chung, Chin-Hyung,Lim, Sung-Bin,Hong, Ki-Seok 대한치주과학회 2005 Journal of Periodontal & Implant Science Vol.35 No.4

The purpose of this study was to compare the effect of desensitizing agents applied on hypersensitive root surface following periodontal treatment. This study included 21 subjects(168 vital teeth). To evaluate dentin sensitivity, three clinical tests(tactile, air stream, cold water) were tried and three different densensitizing agents(MS coat, Elmex gel. Superseal) were individually applied. After application, reassessment was done at 1 minute, 1 week, 1 month and 3 months. The results were as follows : 1. The degree of dentin sensitivity was measured highly in the sequence of cold water, air stream and tactile and significantly decreased in all four groups with lapse of time(p<0.05). 2. There was no significant difference between all four groups in the tactile test with lapse of time. 3. There was no significant difference between three experimental groups in the air stream test with lapse of time. however, one minute later, it was measured highly in the sequence of Superseal, MS coat and Elmex 4. There was no significant difference between three experimental groups in the cold water test with lapse of time. As a result of this study, all of three agents were significantly effective in reducing dentin hypersensitivity and these agents could be positively employed to patients complaining of dentin hypersensitivity following periodontal treatment.

UHF RFID 리더기용 LHCP 안테나 설계 및 제작

박성일,김선일,고영혁,Park, Sung-Il,Kim, Sun-Il,Ko, Young-Hyuk 한국정보통신학회 2010 한국정보통신학회논문지 Vol.14 No.1

본 논문에서는 원형편파를 가진 900MHz 대역 RFID 리더기 안테나를 설계 및 제안하고 실험에 의하여 조사하였다. 900MHz 대역 RFID 리더기 안테나는 좌선편파를 산출할 수 있는 용량을 구성한 단순한 방사기로 제안되었다. 또한, 설계 제작한 900MHz대역 RFID 리더기 원형편파 안테나는 1010MHz 중심주파수 대역에서 -38.28dB의 리턴로스 값을 가지며, 905~1030MHz에서 12.5% 대역폭을 갖는다. 제안한 LHCP 안테나 최대이득은 6dBi이고, 축비가 2이하에서 동작하는 원편파 안테나이다. 측정된 결과, 2기준 이하 축비값은 동작 주파수에서 양호하게 관측되었으며, 제안된 안테나는 무선통신에서 RFID응용을 위해 적합하다. In this paper, a design for the 900MHz bandwidth RFID reader antenna with circular polarization is proposed and experimentally investigated. The 900MHz bandwidth RFID reader antenna is proposed as a simple radiator with loading capacitor to generate LHCP(Left Hand Circular Polarization). Also, the design and fabrication of antenna has the returnloss of -32.28dB at the center frequency of 1010MHz and Bandwidth of 12.5% at 905Hz~1030MHz. Proposed LHCP antenna of maximum gain is 6dBi and satisfy axial ratio based on 2. From the measured result, axial ratios based on 2 are observed at the operating frequencies. The proposed antenna is suitable for RFID applications in wireless communications.

${Ni_3}Al-{Ni_3}V$ 준이원계 합금 포함 삼원계 시스템에서의 meso-scale 미세구조의 전산 모사에 관한 연구

박성일,이혁모,Park, Sung-Il,Lee, Hyuck-Mo 한국재료학회 2001 한국재료학회지 Vol.11 No.11

The meso-scale microstructure of the $Ni-Ni_3Al- Ni_3V$ system is crucial to obtain both high strength and high toughness. Its evolution may be predicted with the aid of computer simulation of the compositional separation for heat-treated alloys. In this study, computer simulations of the hypothetical A-B-C ternary system, which is similar to the $Ni-Ni_3Al- Ni_3V$ system in terms of phase equilibria, have been performed using the kinetic modeling. Simulated morphologies were changed with nominal compositions and model parameters. It was showed the current model was useful and the more realistic model was proposed.

회원작품 - 지우네집(문호리 패시브 주택)

박성일,Park, Sung-il 대한건축사협회 2022 建築士 Vol.641 No.-

견관절 통증에 대한 테이핑적용 증례

박성일,배준호,김용권,Park, Sung-Il,Bae, Jun-Ho,Kim, Yong-Kwon 대한물리치료과학회 1999 대한물리치료과학회지 Vol.6 No.1

Pain is the most common symptom that brings a patient to the hospital. In general, two major interventions in pain control are pharmacotherapy and physical therapy. But recently introduced taping method that release pain at one time. The 7 patient with shoulder problems were applied Arikawa taping approaches. The flexor or extensor patterns were determined by Arikawa method at first, and the patients were tested and applied taping at comfortable patterns. We found that: 1)We applied taping approach to the 7 patient, and all of them improved pain and ROM; 2)If the symptoms and patterns were similar, the taping was attached same point; 3)Although several therapist participated in treatment, the effects are regular. It' s caused by ordinary character of taping approach; 4)The patient can attache easily himself; 5)The taping approach has side effects(skin problems, increasing pain, etc.). But if remove them, it's subside immediately. Thus the taping approach is not hazard.

NEV용 스마트 Off-Board 충전시스템 설계

박성일,이정기,Park, Sung-Il,Lee, Jeong-Gi 한국전자통신학회 2013 한국전자통신학회 논문지 Vol.8 No.10

급격한 원유가격 상승과 환경 친화적 차량에 대한 수요가 증가하면서 전기자동차에 대한 연구개발이 활발히 진행되고 있으며, 특히 근거리 전기자동차(NEV)는 양산 가능성이 매우 높은 무공해 차량으로 관련 기술에 대한 개발이 시급히 요구되는 시점이다. 본 논문에서 연구하고자 하는 중대형 2차전지 On-Board 충전기는 우주항공 및 일반 산업 분야에서도 충분히 응용가능한 요소 기술이고, Off-Board 스탠드형 충전기는 향후 활성화될 충전 인프라 구축 사업에 활용할 수 있을 것으로 예상된다. As oil price and demand for environment friendly vehicle rapidly increase, research on electric car is being widely carried out. Especially, NEV(Neighborhood Electric Vehicle) is a pollution-free vehicle that can be mass-produced which the time of development for related technologies is urgently needed. In this paper the On-Board charger for mid- and large- sized secondary cell is applicable in aerospace and other general industries, and the Off-Board standing charger is expected to be employed in creating charging infrastructure.