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Cefpiramide와 Aminoglycoside의 혼합시 배합 변화
박미정,박광준,박경호,손인자 한국병원약사회 2006 병원약사회지 Vol.23 No.1
Cefpiramide is usually used for the treatment of a documented or suspected infection due to susceptible organisms such as G(-), G(+), P. aeruginosa. Aminoglycoside is used for infection due to G(-) organism. Aminoglycoside is usually used with cefpiramide to widen antibacterial spectrum. So in clinically, this combination used frequently. But, in vitro, when aminoglycosides antibiotics is added to Cephalosporin antibiotics, it is known to be incompatible. In Seoul National University Hospital in Korea, there is a report of incompatibility that when aminoglycoside antibiotic is added to cefpiramide, it will precipitate. So. We study, in vitro, compatibility of cefpiramide with aminoglycoside. The test sample was diluted in D5W, NS. cefpiramide was prepared five different concentrations; 1g/10ml(10%), 1g/20ml(5%), 1g/50ml(2%), 1g/100ml(1%), and 1g/200ml(0.5%). Three aminoglycoside antibiotics were prepared two different concentrations; amikacin(0.5%, 0.125%), gentamicin(0.16%, 0.04%), tobramycin(0.16%, 0.04%) of which prepared sample was mixed 1:1 in different concentration. We took 2 ml that the mixed sample, and observed for precipitation visually and determine the pH with pH meter. Immediately after preparing a injection, we observed signs for incompatibility such as formation of particle, occurrence of haze and gas, increase of turbidity and change of color. In result, compatible concentration range of cefpiramide + aminoglycoside group was 1% + 0.5%, cefpiramide + gentamicin group was incompatible within the range of study concentration, cefpiramide + tobramycin group was 0.5% + 0.16%. And the higher concentration of cefpiramide result in the higher pH of mixed sample to be incompatible.
Chaotic Signal 기반 UWB 통신의 timing 정확도 향상에 관한 구조 연구
박미정,박형철,김학선 한밭대학교 2007 한밭대학교 논문집 Vol.5 No.1
본 논문에서는 송 수신기간의 거리측정을 위해 UWB 시스템에서 chaotic 신호를 이용한 간단한 변·복조 방식인 COOK를 사용하였다. 이 시스템에서 정합펼터 출력 파형의 첨두 (peak) 지점이 송·수신기 간의 거리를 나타낸다- 이러한 특성으로 정합필터의 출력이 첨예해질수록 보다 정확한 위치를 획득할 수 있다. 어떠한 모양의 펄스를 사용해야 첨예한 출력 파형을 얻을 수 있는지를 알기위해 COOK 시스템의 송선기에 여 러 가지의 PSF(Pulse Shaping Filter) 를 추가하였다 구형파, 삼각파, roll-off가 0.25, 0.5, 그리 고 1 인 root raised cosine 신호 형태로 Chaotic signal을 변조하여 5가지 경우를 모의실험 하였다 그 결 과 삼각파 형태의 포락션을 갖는 chaotic 신호를 사용하였을 때가 가장 첨예한 특성이 나온다는 것을 알 수 있었으며 이를 위하여 COOK 변조에서 이러한 삼각파 형태의 chaotic 신호를 송신하기 위한 새로운 구조의 스위치를 제안하여 그 성능을 검증하였다. In this paper, We adapt UWB transceiver that used chaotic signal and simple COOK MODEM for the distance measurement. We can estimate the distance between transmitter and receiver by output waveform of the matched filter in this system. When this output pulse-width of the matched filter is the more sharp we can get the more precise positioning information. We simulated the UWB positioning system which added the PSF(Pulse Shaping Filter) to find out what kind of PSFs made the best sharp pulse. we took into account PSFs of the 5 cases which are a square wave, a chopping wave, a root raised cosine signal with roll-off 0.25, 0.5 and 1. As a result, the best sharp case of the demodulator output waveform characteristic is the a chopping wave. So We suggested new structure switches to generate the a chopping waveform envelope chaotic signal. and We can verify the performance by simulation that new switch architecture in the COOK modulation is matched very well.
A Simple and Reliable Method for Obtaining Entomosporium Monoconidial Isolates
박미정,Quinn A. Holtslag,신현동 한국미생물학회 2011 The journal of microbiology Vol.49 No.2
Monoconidial isolates of Entomosporium mespili were successfully cultured using a simple isolation procedure. A detailed description of the steps required for isolating E. mespili is provided. The characteristic pattern of conidial germination and growth on potato dextrose agar is also described. The process that was successful in obtaining pure isolates involved collecting material in the morning, picking a glistening white mass of conidia under dissecting microscope magnification, depositing a mass of conidia onto a drop of water on a glass slide, streaking the conidial mass onto potato dextrose agar, incubating the plate for 48 h, and transferring the characteristic fan-shaped colonies to fresh medium.