개에서 Tiletamine-Zolazepam 마취에 대한 Doxapram과 Yohimbine의 길항효과

박명호,김명철,Park Myeong-ho,Kim Myung-cheol 한국임상수의학회 1995 한국임상수의학회지 Vol.12 No.1

This study was performed to examine the general anesthetic efficacy of tiletamine-zolazepam, a mixture of phencyclidine-derived tiletamine and benzodiazepine-related zolazepam. The antagonistic activities of doxapram and yohimbine to the anesthetic effects of tiletamine-zolazepam were also studied. Thirty healthy mongrel dogs were divided into three groups (each of 10) twenty minutes after being anesthetized with tiletamine-zolazepam : T-Z-S group(tiletamine-zolazepam-saline), T-Z-D group (tiletamine -zolazepam-doxapram), T-Z-Y group (tiletamine-zolaz.pam-yohim bine). Various parameters wert evaluated in terms of the onset and recovery time of analgesia, respiration rates, hear rates, body temperature, electrocardiogram, blood chemistry, and lymphocyte blastogenesis. The results obtained through these experiment could be summarized as follows: 1. he anesthetic efficacy of tiletamine-zolazepam was considered desirable, with the onset time of anesthesia being as short as 0.23-0.24 minutes. 2. Both of the antagonistic effects of yohimbine and doxapram on the anesthesia induced by liletamine-zolazepan were evaluated statistically significant(p<0.05) as the recovery time was shortened from 39.3$\pm$4.9 min(T-Z-S group) to 25.3$\pm$2.9 nin(T-Z-Y group) and 29.9$\pm$8.8min(T-Z-D group), respectively. 3. Respiration rates were not changed by the treatments of both doxapram and yohimbine, with the only transient increase in the T-Z-D group. The changes in the respiration rate were not observed during the whole time course of the experiment. 4. Yohimbine(T-Z-Y group) increased the heart rate significantly from 30 minutes after the adminstration compared to the T-Z-S group and T-Z-D group (p<0.05). 5. The decreases in th, body temporature were observed from 30 minutes in the T-Z-S group(p<0.05) and 40 minutes in th, T-Z-D group(p<0.05), after the adminstration. On the other hand, there was no hypothermia in the T-Z-Y group. 6. In the all experimental groups of the T-Z-S, T-Z-D and T-Z-Y, there were no specific findings on the electrocardiograph incept slight shift to the tachycardia in all cases. 1. We could not find any differences in the blood chemistry between all experimental groups (T-Z-S, T-Z-D and T-Z-Y). 8. the inhibition of the lymphocyte blastogenesis shown in the T-Z-S with 3 hours decreasing and thereafter restoring to the normal values up to the point 5 hours were not occurred in the T-Z-D and T-Z-Y groups. With the above results, we could conclude that both doxapram and yohimbine can be clinically used as recovery agents towards anesthesia by tiletamine- zolazepam fi:on the efficacy point of view, but yohimbine is more recommendable in this case if considering the recovery time and lymphocyte blastogenesis.

동해 남서부 해역의 제4기 후기 퇴적물과 공극수에서의 퇴적학적 및 지화학적 변화의 의미

박명호,김지훈,류병재,이성숙,한상근,길영우,Park, Myong-Ho,Kim, Ji-Hoon,Ryu, Byong-Jae,Lee, Song-Suk,Han, Sang-Geun,Kil, Young-Woo 한국석유지질학회 2006 한국석유지질학회지 Vol.12 No.1

동해 남서부해역에서 채취한 4개의 코어퇴적물과 공극수를 이용하여 제4기 후기의 층서와 퇴적환경변화를 연구하였다. 이를 위하여 테프라층서, 탄소연대측정, 퇴적상, 퇴적물의 암질, 퇴적물과 공극수의 원소성분 등을 분석하였다. 테프라층서와 탄소연대측정 결과, 코어의 층서는 MIS 3의 중반 시기부터 최상부의 MIS 1 (홀로세)까지 구성되어 있음을 보여준다. 코어의 평균퇴적률은 대부분 $10{\sim}20\;cm/kyr$의 값을 보여주고 있으나, 구간별로 퇴적률은 크게 변동을 한다. 특히 퇴적률은 MIS 2 시기에 상대적으로 높은 값을 보여주고 있는데, 이는 해수면 변동과 관련이 있는 것으로 추정된다. 반면, 측정된 ${\delta}^{13}C_{org}$과 C/N 비를 도식한 결과, 코어의 유기물질은 대부분 해성조류 기원임을 가리킨다. 또한 메탄가스의 ${\delta}^{13}C_{CH4}$ 값을 고려할 때, 메탄가스가 이산화탄소 환원작용의 경로를 따르는 박테리아기원으로 형성되었음을 보여준다. Late Quaternary stratigraphy and sedimentary environmental changes were studied based on four core sediments and their pore water taken from the southwestern part of the East Sea. The results of tephrostratigraphy and radiocarbon dates indicate that the cores cover the time interval from the middle stage of Marine Isotope Stage (MIS) 3 to MIS 1 (Holocene). The average of sedimentation rate in core sediments varies from 10 cm/kyr to 20 cm/kyr, but it fluctuates generally in particular time intervals such as MIS 2, which would be related with the sea-level changes at that time. On the other hand, the relations between ${\delta}^{13}C_{org}$ and C/N ratios suggest that the organic matter in the cores was originated mainly from marine algae. In addition, the value of ${\delta}^{13}C_{CH4}$ indicates bacterial origin rather than thermogenic one.

천연가스 연료의 연소특성에 관한 연구

박명호,이선봉,Park, Myung Ho,Lee, Sun Bong 대한기계학회 1999 大韓機械學會論文集B Vol.23 No.10

This study is concerned about the combustion characteristics of methane-air and methane/hydrogen-air mainly the behavior of burning velocity including the effect of the ignition energy. The experiments were conducted in a spherical combustion bomb designed in this laboratory. The burning velocities were measured by the pressure-time history and the reaction rates were estimated theoretically. The experimental results showed that the burning velocity increased by 25 to 50 percent when hydrogen is added to methane by 20 percent.

소에서 Detomidine 투여에 의한 진정효과 및 혈액성분의 변화

박명호,남치주,권오경,Park Myeung-Ro,Nam Tchi-Chou,Kweon Oh-Kyeong 한국임상수의학회 1989 한국임상수의학회지 Vol.6 No.1

In order to investigate sedative action of detomidine and its effect on physical signs, hematological and blood chemical components, 15 Holstein cattle were used. The dosage of detomidine was 25 ${\mu}$g/kg and 50 ${\mu}$g/kg. Blood was collected before injection, 30, 60 and 120 min. after injection. Induction time of sedation in a cattle given with 25 ${\mu}$g/kg and 50 ${\mu}$g/kg of detomidine was 10.6${\pm}$2.8. 7.6${\pm}$1.0min. respectively and maintenance time was 70.4${\pm}$8.3, 86.5${\pm}$9.9, respectively. After injection of detomidine, body temperature was slightly increased, heart rate and respiratory rate were slightly decreased. The levels of red blood cell, hemoglobin, packed cell volume and white blood cell were not changed by detomidine. Blood glucose level following detomidine was markedly increased but total protein, serum glutamic oxaloacetic transminase, alkaline phosphatase, lactic dehydrogenase, blood urea nitrogen and creatinine were not changed. This results indicated that detomidine was useful sedative in bovine practice.

리카도의 "기계(機械)"에 대한 재해석(再解釋)

박명호,Park, Myeong-Ho 한국개발연구원 1995 KDI Journal of Economic Policy (KDI JEP) Vol.17 No.2

본 연구에서는 리카도가 자신의 "정치경제학(政治經濟學)과 조세(租稅)의 원리(原理)"(이하에서는"원리(原理)"라고 하겠음) 3판에 새로이 도입한 "기계(機械)"의 내용을 중심으로 기술진보(技術進步)가 고용(雇傭)에 미치는 영향(影響)에 대해 살펴보고자 하였다. 리카도는 당시 대부분의 주류 경제학자들과 마찬가지로 과학의 발전과 기술진보로 인한 새로운 기계(機械)의 도입은 근로자, 자본가 및 지주를 포함하는 모든 계급(階級)에게 유리한 결과를 가져오리라 생각하였다. 그러다가 그는 "원리(原理)" 3판을 작성하면서 이러한 자신의 견해가 잘못된 것임을 시인하고, 새로운 기계(機械)의 도입이 근로자(勤勞者)에게는 불리한 결과를 가져올 수 있음을 분석적인 방법으로 보여주었다. 그러나 이러한 리카도의 시도는 당시 및 후대의 경제학자들에 의해서도 지적되었듯이 부분적으로 논리적인 오류(誤謬)를 범하였다. 리카도의 논리적 오류를 수정하면서도 그의 문제의지(問題意識)을 부각시키기 위해 본 연구에서는 힉스에 의해 도입된 신(新)오스트리안(Neo-Austrian) 자본개념(資本槪念)과 이에 입각한 기술진보(技術進步)의 형태분류를 리카도의 분석틀에 적용시켰다. 그 결과 일정한 형태의 기술진보하에서는 수익성이 높은 기계(機械)가 도입될지라도 과도기적으로 고용(雇傭) 및 총생산물(總生産物)에 불리한 효과를 나타낼 수 있음을 보여주게 되었다. 그리고 과도기적으로 기계(機械)의 도입에 따른 기술적(技術的) 실업(失業)이 발생할 경우 그 기간에 영향(影響)을 주는 요인(要因)에 대해서도 살펴보고자 했다.

Ag-20wt% Pd-20wt% Cu 3원합금(元合金) 및 Au첨가합금(添加合金)의 시효경화특성(時效硬化特性)

박명호,배봉진,이화식,이기대,Park, M.H.,Bae, B.J.,Lee, H.S.,Lee, K.D. 대한치과기공학회 1997 대한치과기공학회지 Vol.19 No.1

The Ag-Pd-Cu alloys containing a small amount of Au is commonly used for dental purposes, because this alloy is cheaper than Au-base alloys for clinical use. However, the most important characteristic of this alloy is age-hardenability, which is not exhibited by other Ag-base dental alloys. The specimens used were Ag-20Pd-20Cu ternary alloy and Au addition alloy. These alloys were melted and casted by induction electic furace and centrifugal casting machine in Ar atmoshpere. These specimens were solution treated for 2hr at $800^{\circ}C$ and were then quenched into iced water, and aged at $350{\sim}550^{\circ}C$ Age-hardening characteristics of the small Au-containing Ag-pPd-Cu dental alloys were investigated by means of hardness testing, X-ray diffraction and electron microscope observations, electrical resistance, differential scanning calorimetric, emergy dispersed spectra and electron probe microanalysis. Principal results are as follows : Hardening occured in two stages, I. e., stage I in low temperature and stage II in high temperature regions, during continuous aging. The case of hardening in stage I was due to the formation of the Llo type face centered tetragonal PdCu-ordered phase in the grain interior and hardening in stage I was affedted by the Cu concentration. In stage II, decomposition of the $\alpha$ solid solution to a PdCu ordered phase(L1o type) and an Agrich ${\alpha}2$ phase occurred and a discontiunous precipitation occurred at the grain boundary. Form the electron microscope study, it was concluded that the cause of age-hardening in this alloy is the precipitation of the PdCu ordered phase, which has AuCu I type face-centered tetragonal structure. Precipitation procedure was ${\alpha}\to{\alpha}+{\alpha}2+PdCu\to{\alpha}1+{\alpha}2+PdCu$ at Pd/Cu = 1 Ag-Pd-Cu alloy is more effective dental alloy as ageing treatment and is suitable to isothermal ageing at $450^{\circ}C$.

한국의 과학기술 어디까지 왔나 - PDP기술

박명호,Park, Myeong-Ho 한국과학기술단체총연합회 1999 과학과 기술 Vol.32 No.2

대형화면으로 현장감 넘치는 영상을 즐길 수 있는 디스플레이어에 대한 요구가 증대되고 있다. 대형화, 디지털화, 고정세화, 고화질화 등이 용이한 플라즈마 디스플레이 패널(PDP)이 21세기 멀티미디어시대의 총아로 떠오르고 있다. 우리나라는 90년대 중반부터 본격적인 연구개발에 착수하여 97년 LG전자가 국내 최초로 40인치 PDP개발에 성공하였으며 일본보다 앞서서 세계 최초로 초대형 60인치를 선보이게 되었다.

가철성 국소의치 설계의 기본원리에 관한 고찰

박명호 대구보건대학 1995 대구보건대학 論文集 Vol.15 No.-

Again, a distal extension removable partial denture rotates when forces are applied. Since it can be assumed that this rotation must create predominantly off-vertical forces, location of stabilizing and retentive components in relation to the horizontal axis of rotation of the abutment becomes extremely important. In other words, an abutment tooth will better tolerate off-verrtical forces if these forces accrue as near as possible to the horizontal axis of rotation of the abutment. The axial surface contours of abutment teeth must usually be altered to locate components of direct retainer assemblies more favorably in relation to the abutment's horizontal axis.

국내산(國內産) RDF의 배출(排出)가스 특성(特性) 비교실험(比較實驗)

박명호,Park, Myung-Ho 한국자원리싸이클링학회 2007 資源 리싸이클링 Vol.16 No.6

본 연구는 에너지의 합리적 이용 및 산업폐기물의 재활용을 위하여 고효율 폐기물 고형연료의 개발을 목표로 하였다. 이 분야의 대부분의 연구는 킬른과 같은 대형연소장치에 집중하여 연구가 이루어졌기 때문에 본 연구에서는 화격자연소방식인 열용량 $66{\sim}132m^2$ 규모의 소용량 열시스템에 초점을 맞추었다. 실험은 RDF, 코크스 및 폐타이어 3종류의 연료를 이용하여 질량값 및 열량값의 변화를 측정하였으며 CO, $CO_2$, NO, $NO_2$ 등의 연소가스 분석 실험을 수행하였다. 연소가스분석결과 RDF의 CO 농도값은 코크스와 폐타이어보다 높았으며. RDF 및 코크스의 NO, $CO_2$, $SO_2$의 농도값은 폐타이어보다는 낮은 값을 나타내었다. This study aimed at developing high-efficiency RDF(refuse derived fuels) fuel in order to use RDF energy rationally and to recycle industrial product. As most studies in this area are concentrated in large combustion apparatuses such as kilns, but this study was focused on the small-sized heating systems, applying them directly to grate type boiler which has a heating capacity of $66{\sim}132m^2$. The different kinds of fuel are experimented including RDF. Coke and Waste Tire. First, for this, we experimented and analyzed RDF to see the change in its mass and heating value. Also, four kinds of exhaust gas are sampled by gas analyzer including CO, $CO_2$, NO and $NO_2$ at different temperature. As a result, the levels of CO concentration of RDF are higher than these of coke and waste tire. But, the levels of NO, $CO_2$ and $SO_2$ concentration of RDF and coke were lower then the levels when waste tire is burned.

일반적인 구강보건 지식에 관한 인식도

박명호 대구보건대학 1994 대구보건대학 論文集 Vol.14 No.-

1. In the brushig time of Knowledge of teeth care, after meal showed 88.4% and the three times of brushing frequency Showed the high dental Knowledge as 70.2% (p<0.01) 2. In the Knowledge on the care of dental Proshetic stuff, there isn't any significant difference 3. In the cognitive degree on the dental caries, 'the dental caries occure as not to brush teeth' appeared to 52.1% and the ingestion of sweet food which is a reason of causing a dental caries appeared unexpectedly to 31.6%. So, it was considered to be a result of realized an importance of brushing.