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길상형,이효영,박광열,조경남,백승주,황교민,조성묵,최재혁,Kil, Sang-Hyeong,LEE, Hyo-Yeong,Park, Kwang-Yeol,Jo, Kyung-Nam,Baek, Seung-Jo,Hwang, Kyo-Min,Cho, Seong-Mook,Choi, Jae-Hyeok 대한핵의학기술학회 2014 핵의학 기술 Vol.18 No.1
본 연구의 목적은 고용량 방사성요오드($^{131}I$) 치료 시 완하제(laxatives) 투여가 체내에 불필요한 방사능을 줄이는데 유용한지 알아보고자 하였다. 입원환자 20명(남:여=6:14, 나이 $46.3{\pm}8.1$세)을 대상으로 $^{131}I$ 5,550 MBq을 복용 한 그룹(Group 1)과 $^{131}I$ 5,550 MBq을 복용한 후 16시간 뒤에 완하제(laxatives)를 투여한 그룹(Group 2)으로 나누었다. 16시간, 40시간 후에 감마카메라(Symbia E, Siemens, USA)를 이용하여 전신스캔 하였으며, 위장관부(Gastro-intestinal tract, GI)와 대퇴부(thigh)에 관심영역(region of interest, ROI)을 설정하여 위 장관의 계수 감소율(reduction ratio)를 구하였다. 일정 시간 간격으로 측정기기(RadEye-G10, Thermo Fisher Scientific, USA)를 이용하여 환자로부터 1 m 거리에서 공간선량률(Spatial dose rate)을 측정한 후, Origin 8.5.1 software를 이용하여 그래프로 나타내었다. 완하제(laxatives) 투여에 따른 두 그룹 간 차이는 독립표본 T검정(Independent samples t-test)을 하였다. 방사성요오드($^{131}I$) 복용 후 16시간 $^{131}I$ 전신영상검사에서 위 장관 계수(count)치는 그룹 1은 $2,825{\pm}337$, 그룹 2는 $2,792{\pm}198$였으며(P>0.05), 40시간 $^{131}I$ 전신영상검사에서 그룹 1의 위 장관 계수(count) 치는 $1,623{\pm}179$, 그룹 2의 위 장관 계수(count)치는 $778{\pm}188$였다(P<0.05). 위 장관내 계수 감소율은 그룹 1은 $42.1{\pm}6.3%$, 그룹 2는 $71.2{\pm}7.7%$였다. 일정 시간 간격으로 공간선량률(spatial dose rate)을 측정하여 비교 분석한 결과 완하제(Laxatives)를 투여하기 전에는 두 그룹 간 유의한 차이가 없었으며(P>0.05), 완하제(laxatives) 투여 4시간 후 부터 두 그룹 간 유의한 차이가 있었다(P<0.05). 퇴원 시 측정한 공간선량률(spatial dose rate)은 그룹 1은 $23.8{\pm}6.7{\mu}Sv/h$, 그룹 2는 $8.2{\pm}2.4{\mu}Sv/h$로 완하제(laxatives)를 병용 투여한 환자에서 체내에 남아있는 방사능이 많이 줄어들었다. 완하제(laxatives) 병용 투여는 위 장관에 남아 있는 방사성요오드 ($^{131}I$)의 배출을 원활히 하여 환자의 체내 방사능량을 크게 낮출 수 있었으며 퇴원 시 방사선량률을 효과적으로 낮출 수 있었다. 따라서 퇴원 후 가족 또는 환자 주변의 일반인에 대한 불필요한 방사선 피폭을 줄 일수 있을 것이다. 또한 방사성요오드($^{131}I$)의 생물학적 반감기를 단축시킬 수 있어 환자의 체내에 방사능량이 법적 선량 이하가 되는 시간이 단축되어 효율적인 병실 운영과 관리가 가능하리라 기대 된다. Purpose: Our goals were to evaluate the effect of high dose radioiodine treatment for thyroid cancer by taking in laxatives. Materials and Methods: Twenty patients(M:F=13:7, age $46.3{\pm}8.1\;yrs$) who underwent high dose radioiodine treatment were seperated into Group 1 taking $^{131}I$ 5,500 MBq and Group 2 with the use of laxatives after taking $^{131}I$ 5,500 MBq. The whole body was scanned 16 hours and 40 hours after taking radioactive iodines by using gamma camera, the ROIs were drawn on the gastro-intestinal tract and thigh for calculation of reduction ratio. At particular time during hospitalization, the radioactivity remaining in the body was measured in 1 meter from patient by using survey meter (RadEye-G10, Thermo Fisher Scientific, USA). Schematic presentation of an Origin 8.5.1 software was used for spatial dose rate. Statistical comparison between groups were done using independent samples t-test. P value less than 0.05 was regarded as statistically significant. Results: The reduction ratio in gastro-intestinal 16 hours and 40 hours after taking laxatives is $42.1{\pm}6.3%$ in Group 1 and $72.1{\pm}6.4%$ in Group 2. The spatial dose rate measured when discharging from hospital was $23.8{\pm}6.7{\mu}Sv/h$ in Group 1 and $8.2{\pm}2.4{\mu}Sv/h$ in Group 2. The radioactivity remaining in the body is much decreased at the patient with laxatives(P<0.05). Conclusion: The use in combination with laxatives is helpful for decreasing radioactivity remaining in the body. The radioactive contamination could be decreased at marginal individuals from patients.
심재익 ( Jae Ik Shim ),김택선 ( Taik Seon Kim ),이성종 ( Sung Jong Lee ),이석하 ( Suk Ha Lee ),김영배 ( Young Bae Kim ),윤정로 ( Jong Ro Yoon ),설의상 ( Eui Sang Seol ),박광열 ( Kwang Yeol Park ),강대웅 ( Dae Woong Kang ) 대한골절학회 2001 대한골절학회지 Vol.14 No.3
목적: 대퇴골 간부 골절치료 후 발생한 불유합의 수술적 치료 결과를 임상적 및 방사선학적으로 분석하고자 하였다. 대상 및 방법: 1993년 1월부터 1999년 12월까지 대퇴골 간부 불유합으로 수술한 환자 21예를 대상으로 하였으며 추시 기간은 평균 15개월이었다. 초기 골절의 원인, 형태와 분류 및 불유합의 원인을 임상적 및 방사선학적으로 분석하였다. 불유합의 수술 방법으로 자가골 이식술과 교합성 골수강내 금속정을 이용한 견고한 내고정술을 시행하였으며 골유합의 기간과 결과를 분석하였다. 결과: 평균 골유합 기간은 22주이었으며 21예중 18예(85.7%)에서 골유합 소견을 보였고 합병증으로는 하지 단축과 파행이 2예, 관절 부분 강직이 2예, 천부 감염이 2예이었다. 결론: 대퇴골 간부 불유합의 치료시 그 원인과 형태에 따라 자가골 이식술과 교합성 골수강내 금속정을 이용한 견고한 내고정술로 양호한 결과를 얻을 수 있을 것으로 생각되었다. Purpose: The purpose of this study is to analyze the clinical and radiological result of surgical treatment for femoral shaft nonunion. Materials and methods: From January 1993 to December 1999, 21 cases of femoral shaft nonunion were treated surgically and followed for an average of 15 months. We analyzed initial cause of injuries, classification of fractures, and cause of nonunion in clinically and radiologically. The authors analyzed the average time to union and results after surgical treatment by rigid internal fixation with interlocking intramedullary nail and autogenous bone graft. Results: The mean duration of bony union was 22 weeks and bony union achieved in 18 cases(85.7%) of 21 cases. The complications were shortening of leg length and limping gait in 2 cases, partial limitation of knee joint in 2 cases, superficial infection in 2 cases. Conclusion: Rigid internal fixation with interlocking intrameduallary nail and bone graft is useful method of treatment for femoral shaft nonunion according to cause and type of nonunion.
홍창의,김창균,장덕형,박광열 관동대학교 1999 關大論文集 Vol.27 No.2
Managing traffic accident becomes a critical factor to improve transportation safety. There are urgent needs to synthesize all the business relating traffic accident. An integrated strategy on traffic accident management system has been developed in this study. Exiting conditions and problems for managing traffic accidents are investigated in terms of administrative efficiency, accident reduction rats, systemic hardware public services. Based on the analysis of the present traffic accident management system a new system has been devised by incorporating basic accident data and general traffic data. A newly developed system are divided into six subsystem: traffic accident information management subsystem, traffic accident information search subsystem traffic accident analysis subsystem traffic accident countermearsure establishment shbsystem. traffic accident. Data structure for integrated management system has been classified population. transportation infrastructure, weather traffic accident and references. Expected benefits from this system are provision of basic tool and/or program to establish traffic safety countermeasure protection and minimization of damages caused by accident improvement of administrative efficiency reduction of traffic accident and enhancement of national competetive power against other countries. The system deveolped in this study will be colsely linked with GIS system and automated collision notification system in the future.
양양지역 교차로 신호시스템에 따는 대기오염물질 배출량 변화에 관한 연구
朴光烈 관동대학교 2000 關大論文集 Vol.28 No.2
The objective of this research is to analyze traffic congestion's effect on the chemical reaction of the waste gas. the mixture of CO. HC and NOx etc. Field survey were taken at the two intersections in the area of Yang-yang city. Kang won Province between May 4 and May 6 1998. investigating the traffic status and analyzing fuel consumption. engine displacement by using Transyt-7F. The principal findings of this research and it's implications are summarized as follows. First, signal optimization per stop penalty(CO. HC : 80-115 seconds. NOx :80-175 seconds ) to minimized the exhaust pollutant which was measured at the entry intersection of Yang-yang is different each other. however the coefficient of fuel consumption and SP which was measured at the front of city hall are same. Second, which the correlation of fuel consumption and exhausted pollutant. cycle time is optimal at 130 seconds and it is not sensitive to SP coefficient. Finally, the efficient managing of the intersection including the revising signal interval according to time. season. and weekend volume is required to minimize air pollution.