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AA 아밀로이드증에서 Infliximab (Remicade(R)) 치료
김다함 ( Da Ham Kim ),박경혜 ( Kyeong Hye Park ),이수환 ( Su Hwan Lee ),현신영 ( Shin Young Hyun ),기정혜 ( Jeong Hae Kie ),강이화 ( Ea Wha Kang ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.5
AA amyloidosis is one of the most significant complications of rheumatoid arthritis characterized by the deposition of amyloid A (AA) in multiple organs and tissues in the body. This disorder displays variable clinical symptoms depending upon the involved organ and a diagnosis is rendered through a biopsy of the affected organ, followed by staining using Congo-red which reveals an apple-green birefringence. Fundamental disease control is critical in the treatment of AA amyloidosis. Anti-tumor necrosis factor alpha (anti TNF- ) agents are promising in inducing clinical remission by suppressing systemic inflam α - mation in AA amyloidosis. We report a case of AA amyloidosis in a 71 year old woman with rheumatoid arthritis that responded well to infliximab therapy.
말단비대증 환자에서 소마토스타틴 유사체 사용에 대한 권고안
진상욱 ( Sang Ouk Chin ),구철룡 ( Cheol Ryong Ku ),김병준 ( Byung Joon Kim ),김성운 ( Sung-woon Kim ),박경혜 ( Kyeong Hye Park ),송기호 ( Kee Ho Song ),오승준 ( Seungjoon Oh ),윤현구 ( Hyun Koo Yoon ),이은직 ( Eun Jig Lee ),이정민 대한내과학회 2019 대한내과학회지 Vol.94 No.6
Acromegaly is a chronic disorder caused by excessive growth hormone (GH) secretion. In most cases, the excess GH originates from GH-producing pituitary adenomas. Surgery is the preferred first-line treatment for patients with acromegaly, but medical man-agement is considered when the disease persists after surgery or in cases where patients refuse surgery or are poor candidates for surgery. Somatostatin analogues are commonly used to treat acromegaly. The Korean Endocrine Society and the Korean Neuroendocrine Study Group have developed a position statement for the use of somatostatin analogues in the medical treatment of acromegaly. This position statement is based on evidence from the current literature and expert opinions. In the case of discrep-ancies among expert opinions, the experts voted to determine the recommended approach. (Korean J Med 2019;94:485-494)