감초 약침액의 항암 및 면역활성에 미치는 영향

박경미,조경희,손윤희,임종국,남경수,Park, Gyung-Mi,Cho, Kyoung-Hee,Shon, Yun-Hee,Lim, Jong-Kook,Nam, Kyung-Soo 한국생약학회 2000 생약학회지 Vol.31 No.1

Glycyrrhizae Radix aqua-acupuncture solution (GRAS) and Glycyrrhizae Radix water-extracted solution (GRWS) were prepared and tested for organ toxicities, antitumor activities, and immunomodulatory effects. The organ-toxicity of GRAS to male ICR mice was studied by the measurements of glutamic oxaloacetic transaminase (GOT), glutamic pyruvate transaminase (GPT), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP-s) activities after injection of GRAS for 7 days. The activities of GOT, GPT, LDH, ALP-s were decreased with GRAS. It was shown to possess considerable toxicity toward various tumor cell lines. Concentration of GRAS at 1.5g/ml and 3g/ml resulted in more than 80% inhibition of growth in Ehrlich ascites tumor cells (EATC), Hepa1c1c7, and HeLa cells. Toxicity of GRAS to A549 revealed that 68% inhibition of growth. GRWS at the concentration of 3g/ml showed more than 80% inhibition of growth with EATC, Hepalclc7, A549 and HeLa. In morphological study, the number of cells were decreased, and the shape of cells was round-form in EATC, Hepalclc7, A549 and HeLa cells with GRAS. Administration of GRAS inhibited the growth of EATC in vivo. Mice given EATC at 1.5g/ml or 0.3g/ml GRAS had 16.7% to 50% survival after 21 days. GRAS increased the proliferation of T and B cells and the cytolytic activity of purified T cell. The biosyntheses of nucleic acid and protein of EATC, Hepalclc7, A549 and HeLa cells were inhibited by GRAS.

N-pole 종류의 FSS가 결합된 복합재료 구조의 잔류응력과 전파투과특성

박경미,황인한,전흥재,홍익표,박용배,김윤재,Park, Kyoung Mi,Hwang, In Han,Chun, Heoung Jae,Hong, Ic Pyo,Park, Yong Bae,Kim, Yoon Jae 한국전산구조공학회 2013 한국전산구조공학회논문집 Vol.26 No.2

본 논문에서는 주파수 선택적 투과막(FSS)이 결합된 복합재료 구조에서 구성 재료 간의 열팽창계수 차이로 잔류응력이 발생하므로 이로 인한 층간분리나 FSS의 손상 등 구조적인 파손 가능성과 잔류응력으로 인하여 변형된 FSS가 전파투과특성에 미치는 영향에 대하여 연구하였다. FSS는 단위요소의 종류, 설계변수, 배열에 따라 전파특성이 다르게 나타나므로, PSO 알고리즘을 이용하여 다이폴이 목표주파수에서 투과특성을 갖도록 설계하고 그 설계치수를 다른 N-pole 종류 단위요소(Tripole, Cross dipole, Jerusalem cross)에 적용하여, 복합재료 구조에 발생하는 잔류응력과 그로인한 구조적 손상과 전파 특성을 영향성을 관찰하고 FSS패턴과 복합재료의 적층 변화에 따라 비교하였다. In this paper, the delamination and failures in frequency selected surface(FSS) caused by residual stresses in the FSS embedded hybrid composites due to the difference between the coefficients of thermal expansion of components and the transmission characteristic changes due to deformation of FSS patterns by residual stresses were studied. FSS may have different electromagnetic characteristics depending on the type of element, design variables, and arrangement. Design variables of dipole FSS were determined using PSO(Particle Swarm Optimization) to obtain the transmission characteristic for the target resonant frequency. Subsequently, the design variables of other types of N-pole(tripole, cross dipole, and Jerusalem cross) were determined based on the dimensions of the dipole for the comparisons of residual stresses of FSS embedded composite structures and transmission characteristics. In addition, effects of FSS pattern, and stacking sequence of composite laminates were considered.

주파수 선택막이 삽입된 복합재 평판의 잔류 열응력과 스프링 백 효과

박경미,서윤석,전흥재,홍익표,박용배,김윤재,Park, Kyoung-Mi,Seo, Yun-Seok,Chun, Heoung-Jae,Hong, Ic-Pyo,Park, Yong-Bae,Kim, Yun-Jae 한국전산구조공학회 2013 한국전산구조공학회논문집 Vol.26 No.6

복합재료 사이에 주파수 선택적 투과막(Frequency Selective Surface)을 삽입하여 동시경화 공정을 이용하여 주파수 선택적 투과 기능을 가지는 하이브리드 복합재료를 성형하면 재료들 간의 열팽창 계수와 강성의 차이로 인해 구조 내에 잔류 열응력이 발생하게 되고, 이로 인하여 스프링 백 현상이 발생한다. 따라서 복합재의 적층에 따른 영향을 알아보기 위해 복합재료의 적층각을 선택적 투과막(Frequency Selective Surface)을 중심으로 대칭과 비대칭 적층으로 적용하여 하이브리드 구조의 잔류 열응력을 예측하고, 이에 대한 스프링 백에 대해서 연구하였다. The residual stresses occur in the Frequency Selective Surface(FSS) embedded hybrid composite structures after co-curing due to mismatch among the coefficient of thermal expansions and stiffness values between the FSS and composite materials. The spring backs occur due to these residual stresses. Therefore, in this paper, the spring-backs caused by residual stresses in FSS embedded composite structures were studied with considering effect of symmetric and unsymmetric stacking sequence of composite laminates.

사업부 간 자원공유

박경미(Park, Kyoung Mi),황재원(Hwang, Jae Won) 한국인사관리학회 2009 조직과 인사관리연구 Vol.33 No.4

우리나라의 다각화된 기업들은 계열사 내에 사업부가 존재하는, 이중으로 다각화된 구조를 가지고 있다. 하지만 다각화 연구에서 자원공유에 관한 논의들은 주로 계열사들을 대상으로 이루어졌기 때문에 상대적으로 사업부 간 자원공유에 대한 관심은 부족하였다. 일부 연구들은 사업부에 관심을 가지기도 하였으나 계열사를 대상으로 하는 이론들을 분석수준만 달리하여 적용하는 수준에 그치고 있다. 하지만 다양한 사업영역에 걸쳐 존재하는 계열사들과는 달리, 사업부들은 동 일하거나 유사한 사업영역 내에 위치하기 때문에 조직부문들 간의 동질성이 상대적으로 높다는 특성을 가진다. 따라서 사업부 간 자원공유에 대한 논의는 계열사 간 자원공유와는 구분되는 논리를 토대로 진행되어야 한다는 것이 본 논문의 주장이다. 이에 따라 본 논문은 사업부 간 관련성, 계열사의 경쟁전략, 계열사가 보유한 자원의 유연성, 계열사가 직면한 환경의 불확실성을 사업부 간 자원공유의 네 가지 결정요인을 제시하고, 분석수준이 달라짐에 따라 자원공유의 논리가 어떻게 달라져야 하는지에 대한 내용을 중심으로 논의를 전개하고 있다. 또한 본 논문은 시너지와 경쟁우위에 대한 논의가 독립적으로 이루어지는 전통적인 다각화 연구의 접근방식과는 달리, 경쟁우위의 관점에서 시너지의 문제를 다루고자 하였다. 특히 본 논문은 계열사와 사업부 간의 유사성 보다는 상이성에 초점을 맞추어 사업부 간 자원공유의 문제에 접근함으로써 기존의 연구들에 대해 차별성을 가진다. Different from the SBU of U.S. multi-business firms, the subsidiary of Korean diversified firms has its own business divisions, which might be described as the duplicated diversification. There has been rare concern in resource sharing among divisions as the theories on resource sharing in diversification research target subsidiaries. A few studies are interested in division' affairs, but they only refer to the theories for subsidiaries. Subsidiaries are widely distributed over various industries, while divisions are placed in a single or similar industries leading divisional relations to be relatively homogeneous. We argue that the studies on inter-divisional resource sharing should be based on differentiated logic distinct from those on inter-subsidiary resource sharing. We suggest inter-divisional relatedness, competitive strategy, resource flexibility, and environmental uncertainty as the determinants of resource sharing among divisions and compare the logic in inter-divisional resource sharing to that in inter-subsidiary resource sharing. We also view resource sharing as a means of gaining competitive advantage, which is different from the existing approaches regarding synergy and competitiveness as separative issues. Our contribution is that we focus on divergencies between subsidiary and division, not similarities which the prior studies rest on.

미생물 및 아미노산 액비가 토마토의 역병 발생과 토양 특성에 미치는 영향

박경미 ( Kyoung Mi Park ),장영희 ( Young Hee Jang ),이승환 ( Seung Hwan Lee ),이훈섭 ( Hun Seop Lee ),이규승 ( Kyu Seung Lee ) 한국환경농학회 2009 한국환경농학회 학술대회집 Vol.2009 No.1

농협조직에서의 시너지 창출: 기업조직과의 비교연구

박경미 ( Kyoung Mi Park ),황재원 ( Jae Won Hwang ) 한국협동조합학회 2014 韓國協同組合硏究 Vol.32 No.2

This study explores the determinants of resource sharing and its impacts on organizational performance in Agricultural Cooperative Federation. We claim resource sharing is one of the most critical alternatives in improving internal efficiency and suggest relatedness, competitive strategy, and environmental uncertainty as the determinants of resource sharing. Our argument is having highly related connection, seeking cost-leadership strategy, facing low uncertain environment encourage more resource sharing and lead to increasement of performance. The empirical results support our ideas on relatedness and environmental uncertainty, but we find no evidence in competitive strategy. We also compare our empirical results with those of diversified firms and get the same results. It shows our logic has general applicability. According to the ratio analyses, Agricultural Cooperative Federation shares more resources for the same level of relatedness and less resources for the same level of environmental uncertainty than diversified firms do. The implication of the study is the universality of resource sharing theory is confirmed and a practical proposal for increasing efficiency of resource sharing in Agricultural Cooperative Federation is suggested.

계열사의 전략적 상황에 따른 계열사 간 및 계열사 내 자원공유의 선택모형

박경미(Kyoung Mi Park),권구혁(Ku Hyuk Kwon) 한국경영학회 2009 經營學硏究 Vol.38 No.2

Existing diversification researches in Korea have accepted the theories for american diversified firms without question. However, the research practice like this may cause a theoretical problem in that Korean diversified firms are so different in organizational structure compared to american ones. The organizational structure of Korean diversified firm is based on a triple-tier system composed of corporate, business, and divisional levels whereas an american one has only corporate and business levels. Due to structural distinction of Korean diversified firm, the logics need to be separately identified according to an organizational level to which it is applied. The issue of resource sharing is also unexceptional. The logic should be differentiated whether the resources are shared between businesses or between divisions within a business. It is stressed in this paper that resource sharing at each level has its own logic. We present relatedness, strategic mission, competitive strategy, and resource attractiveness measured at a business level as the determinants of resource sharing and clarifies which determinant would be effective in resource sharing between businesses or resource sharing within a business. We could get the following results by testing the hypotheses. First, industrial and resource relatedness affect resource sharing between businesses in a positive way, whereas neither has an influence on resource sharing within a business. Second, it is suggested that a build mission would be related to resource sharing between businesses and a harvest mission would be related to resource sharing within a business. However, neither one is significantly supported. We infer the reason from the possibility that the business units to which a build or a harvest mission is assigned indiscriminately involve in resource sharing between businesses because a business unit with a build mission is supposed to be given the resources from other ones whereas the one with a harvest mission is supposed to give. As the fact that a business unit with a hold mission falls on the cell of star in the BCG matrix indicates that it should feed itself, it is encouraged to share the resources inside to efficiently utilize its own resources rather than to give or to be given them. A business unit with a divest mission might not share the resources with other business units as it prepares for being sold or liquidated. Third, a differentiation strategy affects resource sharing between businesses, but it does not affect resource sharing within a business. In contrast, a low-cost strategy does not affect resource sharing between businesses, but it affects resource sharing within a business. Fourth, resource value is positively influential to resource sharing within a business. Also, resource level is related to resource sharing within a business in a positive way and is related to resource sharing between businesses in a negative way. We expect that resource value would not affect resource sharing between businesses because of its inimitability, but the result shows that it does affect. It implies that the inimitability of resources blocks transferring not between different industries but between different organizations as the reason why the resource cannot be imitated is rooted in organizational specificity such as path dependence or tacitness. It would not be so easy for the business units which resides in the different firms to replicate other one`s resources even if they are in the same industry. However, those in the same firm would not have such a difficulty in imitating the resources in spite of industrial differences. The contributions of this study could be summarized as follows. First of all, we argue that a differentiated logic should be applied to each of the organizational levels. On the contrary of existing researches which use a homogenized logic regardless of an organizational level to which it is applied, we stress that a discriminative logi

계열사 간 자원공유와 사업부 간 자원공유의 결정요인 및 성과함의

박경미(Kyoung Mi Park),권구혁(Ku Hyuk Kwon) 한국경영학회 2007 한국경영학회 통합학술발표논문집 Vol.2007 No.8

본 논문에서는 그룹본부-계열사-사업부로 이루어진 우리나라 재벌그룹의 구조적 특성을 반영하여, 계열사가 처한 상황적 요인에 따라 계열사 간 자원공유와 사업부 간 자원공유가 차별적으로 결정된다는 논의를 중심으로 가설을 제시하고, 이를 검증하였다. 또한 본 논문에서는 계열사의 성과에 대한 계열사 간 자원공유와 사업부 간 자원공유의 상충적 관계도 함께 다루었다. 본 논문에서는 가설검증을 통해 다음의 결론을 얻을 수 있었다. 첫째, 계열사의 타계열사에 대한 산업의 관련성과 자원의 관련성은 계열사 간 자원공유에 긍정적인 영향을 미치는 것으로 나타났다. 둘째, 계열사의 차별화 전략은 계열사 간 자원공유에 긍정적인 영향을 미치는 것으로 나타났으며, 계열사의 원가우위 전략은 사업부 간 자원공유에 긍정적인 영향을 미치는 것으로 나타났다. 셋째, 계열사의 보유자원의 가치와 계열사의 자원보유수준이 높은 경우 사업부 간 자원공유에 긍정적인 영향을 미치는 것으로 나타났으며, 계열사의 자원보유 수준이 낮을수록 계열사 간 자원공유를 많이 하는 것으로 나타났다. 넷째, 자원의 매력도와 성과와의 관계를 보면, 계열사의 보유자원의 가치가 높을수록, 자원보유수준이 높을수록 계열사의 성과에 긍정적인 영향을 미치는 것으로 나타났다. 마지막으로, 자원공유와 시너지 효과, 그리고 계열사 성과와의 관계를 보면, 사업부 간 자원공유는 계열사 성과에 긍정적인 영향을 미치지만, 계열사 간 자원공유는 계열사 성과에 긍정적인 영향을 미치지 않는 것으로 나타났다. 계열사 간 자원공유의 경우에는 시너지 효과가 전제될 때에만 계열사 성과에 긍정적인 영향을 미치는 것으로 나타났으며, 사업부 간 자원공유는 계열사 간 자원공유가 계열사의 시너지 효과에 미치는 영향을 제한하는 것으로 나타났다. 본 논문에서는 기업본부-계열사-사업부의 특성을 반영하는 통합적 분석틀과 분석수준에 따른 차별적 논리를 제시하였으며, 특히 계열사 간 자원공유와 사업부 간 자원공유의 관계와, 이들이 계열사의 성과에 미치는 영향을 실증연구를 통해 입증했다는 점에서 의의를 찾을 수 있다. This study reflects the structural uniqueness of a Korean chaebol composed of the headquarter, subsidiaries, and divisions and suggests the differentiated determinants of resource sharing between and within subsidiaries. The study also touches on the conflicting effects of each level of resource sharing on a subsidiary`s performance. The empirical results lead to the following conclusions. First, industry relatedness and resource relatedness both determines resource sharing between subsidiaries. Second, differentiation strategy determines resource sharing between subsidiaries and low-cost strategy, on the other hand, determines resource sharing within a subsidiary. Third, resource value and resource level both determine resource sharing within a subsidiary, but resource level negatively influences resource sharing between subsidiaries. Fourth, resource value and resource level both determine a subsidiary`s performance. Fifth, resource sharing within a subsidiary influences performance, but resource sharing between subsidiaries does not. Resource sharing between subsidiaries influences performance on condition that a subsidiary`s synergy effect exists and resource sharing within a subsidiary controls the influence of resource sharing between subsidiaries on synergy effect. This paper proposes the integrated framework that contains and characterizes the organizational structure of a Korean chaebol and suggests the differentiated logic aligned with it. It is another implication of the study to investigate and verify the relationship between each level of resource sharing and its influences on a subsidiary`s performance.

착과량 조절이 ‘어윈’ 망고의 과실품질에 미치는 영향

박경미(Kyoung Mi Park),천미건(Mi Geon Cheon),이서현(Seo Hyun Lee),최성태(Seong Tae Choi),황연현(Yeon Hyeon Hwang),장영호(Young Ho Chang) 한국원예학회 2022 한국원예학회 학술발표요지 Vol.2022 No.5

조직문화의 조직 내 차별적 영향: 지역농협을 대상으로

박경미 ( Kyoung Mi Park ),황재원 ( Jae Won Hwang ) 한국협동조합학회 2013 韓國協同組合硏究 Vol.31 No.2

This study investigates the differentiated influences of organizational culture on organizational effectiveness. Our argument is that a different organizational culture affects job performance according to both group-level and individual-level conditions. Quinn & McGrath (1985)`s typology of organizational culture is applied to regional agricultural cooperatives. Our empirical analyses imply that developmental culture, group culture, hierarchical culture, and rational culture affect job performance in a general condition. But the valid influence of organizational culture is varied with location, number of cooperative members, number of employees, years of employment, self-efficacy in specific conditions. The study contributes to existing research by providing an insight that it is desirable for increasing organizational effectiveness not to infuse a standardized organizational culture into all of the members but to implant a customized organizational culture targeted to each of the members.