농촌 지역 주민의 혈청 Ferritin 수준과 대사증후군과의 관련성

류소연,김기순,박종,강명근,한미아,Ryu, So-Yeon,Kim, Ki-Soon,Park, Jong,Kang, Myeng-Guen,Han, Mi-Ah 대한예방의학회 2008 예방의학회지 Vol.41 No.2

Objectives : The purpose of this study was to examine the relationship between serum ferritin and the metabolic syndrome (MS). Methods : We conducted a cross-sectional study of 1,444 adults over age 40 and under age 70 that lived in a rural area and participated in a survey conducted as part of the Korean Rural Genomic Cohort Study (KRGCS). The MS was defined as the presence of at least three of the followings : elevated blood pressure, low high density lipoprotein cholesterol, elevated serum triglycerides, elevated plasma glucose, or abdominal obesity. After adjustment for age, alcohol intake, menopausal status, body mass index (BMI), high sensitivity C-reactive protein (hs-CRP), and alanine aminotransferase (ALT), odds ratios (ORs) for the prevalence of the MS by sex were calculated for quartiles of serum ferritin using logistic regression analysis. Results : The MS was more common in those persons , with the highest levels of serum ferritin, compared to persons with the lowest levels, in men (37.1% vs. 22.4%, p=0.006) and women (58.8% vs. 34.8, p<0.001). In both sexes, the greater the number of MS components presents, the greater the serum ferritin levels. After adjustment for age, alcohol intake, and menopausal status, the OR for metabolic syndrome, comparing the fourth quartile of ferritin with the first quartile, was 2.21 (95% confidence interval; CI=1.26-3.87; p-trend=0.024) in men and 2.10 (95% CI=1.40-3.17; p-trend=0.001) in women. However, after further adjustment for BMI, hs-CRP, and ALT, the ORs were statistically attenuated in both sexes. Conclusions : Moderately elevated serum ferritin levels were not independently associated with the prevalence of the MS after adjusting for other risk factors. Further studies are needed to obtain evidence concerning the association between serum ferritin levels and the MS.

일부 사립대학 교직원의 요통 관련인자에 관한 연구

류소연,이철갑,박종,김기순,김양옥,Ryu, So-Yeon,Lee, Chul-Gab,Park, Jong,Kim, Ki-Soon,Kim, Yang-Ok 대한예방의학회 1996 Journal of Preventive Medicine and Public Health Vol.29 No.3

This study was performed to find the prevalence and the associated risk factors with low back pain(LBP) of the staffs in a university at Kwang-ju city. The data were collected by a questionnaire including SDS(self - rating depression Scale) battery from September 1st to October 15th, 1996. The results were as follows; 1. The prevalence rate of LBP during lifetime was 73.1%, 53.1% for the last one year, and 23.6% for the last one week. 2. Statistically significant factors related to LBP during lifetime were sex and satisfaction with job. Sex, smoking, alcohol drinking, occupation, work posture, forward bending of trunk and satisfaction with job were selected as significant factors related to LBP during the last one year. The significant determinants related with LBP during the last one week were sex, smoking, alcohol drinking, occupation, forward bending of trunk and satisfaction with job. 3. Through the analysis of self - rating depression scores according to LBP, respondents with LBP had the significantly higher value of physiological disturbances and lower value of psychomotor activities than those without LBP. 4. Through the multivariate logistic regression, significantly associated factors with LBP during lifetime were selected to be female(OR=2.63, 95% CI : $1.08\sim6.40$), dissatisfaction with job(OR=2.16, 95% CI : $1.16\sim4.15$), those for the last one year were chosen to be female(OR=2.30, 95% CI : $1.03\sim5.12$), forward bending of trunk(OR=2.18, 95% CI : $1.26\sim3.79$), dissatisfaction with job(OR=1.84, 95% CI : $1.06\sim3.21$), and those for the last one week were female(OR=3.00, 95% CI : $1.17\sim7.69$), forward bending of trunk(OR=2.85, 95% CI : $1.38\sim5.88$). In conclusion, for effective prevention of the LBP at work site, appropriate improvement of work posture and various psychological factors should be considered.

일부 농촌주민의 혈압과 사회적 지지도와의 관련성

류소연,이철갑,박종,김기순,Ryu, So-Yeon,Lee, Chul-Gab,Park, Jong,Kim, Ki-Soon 대한예방의학회 2001 Journal of Preventive Medicine and Public Health Vol.34 No.4

Objectives : This study was peformed to assess the association between the social support and blood pressure(BP) in a rural community. Methods : A cross-sectional survey, comprising a health examination including BP, height and weight and a questionnaire-based interview which investigated social support, demographic factors, smoking, drinking, and etc. was peformed between February 10th and March 5th, 1998. The survey included 318 persons who were over than 30-year-old in the rural community of Kwangju, Republic of Korea. We excluded persons who taking antihypertensive medications or who provided incomplete information; we subsequently analyzed the data from 284 persons. In order to test the hypothesis of an association between BP and social support controlling confounders such as age, educational level, working time, body mass index, smoking and drinking, the data was analyzed using multiple linear regression analysis. Results : The subjects were composed of 109(38.4%) males and 175(61.6%) females with mean ages of 62.0 years and 61.1 years, respectively. The hypertension prevalence was 41.3% among males and 45.1% among females. In the correlation analysis, higher total social support scores correlated significantly with lower systolic BP in both males and females. The hypertension prevalence increased significantly with the decreasing of the social support in males. In multiple regression analysis, systolic and diastolic blood pressure showed a negative association with social support in both males and females, although this was not statistically significant. Conclusions : Larger and broader studies are required in the future in order to identify the association between the social support and BP.

혈중 감마지티피와 청소년 대사증후군과의 관련성

류소연 ( So Yeon Ryu ),권순석 ( Sun-seog Kweon ),신민호 ( Min-ho Shin ),박형철 ( Hyung-chul Park ) 한국모자보건학회 2008 한국모자보건학회지 Vol.12 No.1

Objectives : This study was performed to investigate the association between serum gamma- glutamyltransferase (GGT) and the metabolic syndrome (MS) in Korean adolescents. Methods : Data were obtained from 1,372 students aged 12~13y with normal liver functions of 7 middle schools in a district of Gwang-ju. Serum GGT, alanine aminotransferase (ALT), body mass index(BMI), waist circumference, blood pressure, fasting glucose and lipid profiles were measured. MS was defined by criteria analogous to ATP Ⅲ as ≥3 of the following: 1) fasting triglycerides ≥100 mg/dL, 2) HDL-cholesterol < 50 mg/dL, 3) fasting glucose ≥110 mg/dL, 4) waist circumference >75th percentile for age and gender, and 5) systolic blood pressure >90th percentile for gender, age, and height. GGT quartiles were formed in assessing the likelihood of MS in logistic regression models that controlled for confounders such as sex, overweight and serum ALT. Results : The prevalence of MS was 5.2% (5.6% for male and 4.9% for female). The MS and its components were significantly related to increased serum GGT level except for HDL-cholesterol and fasting glucose. After the adjustment for sex, overweight and serum alanine aminotransferase (ALT), the association with the MS was attenuated, but the OR for MS was 2.06 (95% Confidence Interval: 1.02~4.17) in the highest compared with the lowest quartile of serum GGT. Conclusions : This study shows that serum GGT level, even within its normal range, is associated with the MS in Korean adolescents.

남자 흡연자의 금연의도 관련 요인

류소연(So-Yeon Ryu),신준호(Jun-Ho Shin),강명근(Myeng-Guen Kang),박종(Jong Park) 한국보건교육건강증진학회 2011 보건교육건강증진학회지 Vol.28 No.2

지역사회 거주 50세 이상 성인의 동맥경직도와 염증반응인자와의 관련성

류소연(So Yeon Ryu),신민호(Min-Ho Shin),이영훈(Young-Hoon Lee),최진수(Jin-Su Choi),박경수(Kyeong-Soo Park),남해성(Hae-Sung Nam),정슬기(Seul-Ki Jeong),권순석(Sun-Seog Kweon) 한국농촌의학 지역보건학회 2011 농촌의학·지역보건 Vol.36 No.2

50세 이상 건강한 성인을 대상으로 baPWV로 측정한 동맥경직도 수준과 염증인자와 동맥경직도와의 관련성을 파악하기 위하여 본 연구를 수행하였다. 2007년과 2008년에 수행된 광주광역시 동구연구(Dong-gu Study)의 기반조사에 참여한 50세 이상 주민 4617명을 대상으로 하였으며, 다중회귀분석을 시행하여 전통적인 심뇌혈관질환 위험요인을 통제한 상태에서 baPWV와 CRP, GGT와 WBC 등의 염증반응인자와의 관련성을 알아보았다. 평균 baPWV는 남자 17.0±4.0 ㎧, 여자 16.2±3.6 ㎧로 남, 여 간에 통계적으로 유의한 차이가 있었고, 연령이 증가할수록 baPWV는 통계적으로 유의하게 증가하는 경향을 보였다. 성, 연령, 흡연상태, 체질량지수, 수축기혈압, 공복혈당, 고혈압 또는 당뇨병의 투약 여부, 혈청 지질, 요산과 ALT 등의 전통적인 심뇌혈관질환 위험요인을 통제한 상태에서 WBC (β=0.158, p<0.0001), hs-CRP(β=0.244, p=0.026)와 GGT (β=0.003, p<0.0001)는 baPWV와 통계적으로 유의하게 독립적인 관련성이 있음을 알 수 있었다. 결론적으로 baPWV로 측정한 동맥경직도 지표는 염증반응인자와 관련이 있음을 알 수 있었다. baPWV 등의 동맥경직도 측정 지표는 동맥 기능의 초기변화를 반영하고 일반적으로 알려져 있는 심혈관질환 위험요인과 유의한 상관관계를 가지고 있어, 이를 이용하여 심혈관질환의 위험을 예측하는데 활용할 수 있을 것으로 생각된다. Objectives: The aim of this study is to determine arterial stiffness levels as measured by brachial-ankle pulse wave velocity (baPWV) and to identify the association between arterial stiffness and inflammatory markers, in healthy adults over 50 years old. Methods: The study population consisted of 4617 persons over the age of 50 years who participated in the baseline survey of the Dong-gu Study, which was conducted in 2007 and 2008. Arterial stiffness was measured using baPWV. A multiple regression analysis was performed to assess the relationship between conventional cardiovascular risk factors and inflammatory markers, including white blood cell (WBC) counts, high-sensitive C-reactive protein (hs-CRP), and gamma glutamyltransferase (GGT). Results: After adjustment for conventional cardiovascular risk factors including sex, age, smoking status, body mass index, systolic blood pressure, fasting glucose, hypertension or diabetic medication, total cholesterol, triglycerides, uric acid, and alanine aminotransferase, baPWV was significantly associated with WBC counts (β=0.158, p<0.0001), hs-CRP (β=0.244, p=0.026), and GGT (β=0.003, p<0.0001). Conclusion: This study shows that arterial stiffness correlates with inflammatory markers. Arterial stiffness may be used as a composite risk factor to identify persons with higher risk for cardiovascular disease. Additionally, arterial stiffness may be a marker for future cardiovascular disease and a target for prevention.

광주광역시 요양시설 코로나19 집단 발생 사례에서 코로나19 백신 접종에 의한 사망 예방 효과

류소연(So Yeon Ryu),조준휘(Jun Hwi Cho),이란(Ran Lee),박소영(So Yeong Park),정다운(Daun Jung),배소현(So Hyun Bae),고화평(HwaPyeong Ko) 한국농촌의학 지역보건학회 2022 농촌의학·지역보건 Vol.47 No.2

Objectives: The purpose of this study was to identify the effectiveness of COVID-19 vaccinations on deaths of the COVID-19 cases in some elderly long-term care facilities (LTCF) in Gwangju Metropolitan City. Methods: The study subjects were 659 COVID-19 cases in residents of 7 elderly LTCF, Gwangju, from 21 Dec. 2021 to 28 Jan. 2022. The used variables were confirmed dates for COVID-19, demographic characteristics, co-morbidities, presentation of symptoms, death and vaccination related characteristics including type of vaccine, doses and dates. Vaccination status were classified as not vaccinated, partially and fully vaccinated. The associations of vaccination status and deaths of COVID-19 cases were tested by chi-square test and multiple logistic regression analysis. Results: The rates of not vaccinated, partially vaccinated and fully vaccinated were 19.4%, 10.2% and 70.4%, respectively. The mortality rate of the cases was 6.4%. The death rate by vaccination status was 16.4% in not vaccinated, 15.4% in partially vaccinated and 2.6% in fully vaccinated, showing a statistically significant difference. The adjusted odds ratios (ORs) (95% confidence intervals, CIs) of death compared to fully vaccinated were 7.64 (3.87-16.34) in non-vaccinated, and 6.97 (3.44-14.14) in partially vaccinated. Conclusions: COVID-19 vaccination seems to work effectively in preventing deaths of COVID-19 cases of elderly LTCF residents. This finding support that fully vaccinations in high risk group such as elderly LTCF residents is very important for one of strategies of COVID-19 management.

주관적 구강건강 불편 및 치과치료 필요 환자에서 미충족 치과의료 관련요인: 제6기 3차년도(2015) 국민건강영양조사 자료

김소영 ( So Yeong Kim ),박종 ( Jong Park ),류소연 ( So-yeon Ryu ),최성우 ( Seong-woo Choi ) 한국보건정보통계학회(구 한국보건통계학회) 2020 보건정보통계학회지 Vol.45 No.2

Objectives: The purpose of the study was to investigate the factors affecting unmet dental care needs in requiring oral health problems and dental care patients. Methods: The study subjects were 3,213 oral health problems and dental care patients who participated in the first year of the Korea National Health and Nutrition Examination Survey (KNHANES 2015). The data were analyzed by frequency analysis, Rao- Scott chi-square test, t-test, and binary logistic regression analysis. data were analysis using IBM SPSS 25.0 program. Results: In multiple logistic regression analysis, the odds ratio (OR) for unmet dental care needs in middle school graduates (OR=1.39, 95% confidence interval, 95% CI=1.05-1.92), and high school graduates (OR=1.37, 95% CI= 1.03-1.83), and college graduates (OR=1.42, 95% CI=1.05-1.93) than below elementary school graduates. And unmet dental care needs in not economically active group (OR=1.25, 95% CI=1.01-1.55) than economic activity group had higher odds. Also, the odds ratio for unmet dental care needs in unmet medical needs group (OR=3.46, 95% CI=2.65-4.52) than receive medical care group had significantly higher odds. Conclusions: Those who are high learning group, and not economically active group, and unmet medical needs group had much higher unmet dental care needs. Further study is needed to analyze the association between unmet medical needs and unmet dental care needs.

치과 내원 흡연자의 전자담배 사용 및 사용의도 관련요인

김소영 ( So Yeong Kim ),박종 ( Jong Park ),류소연 ( So Yeon Ryu ),한미아 ( Mi Ah Han ),최성우 ( Seong Woo Choi ) 한국보건정보통계학회(구 한국보건통계학회) 2020 보건정보통계학회지 Vol.45 No.1

Objectives: This study was to investigate the factors affecting the use of electronic cigarettes and intent to use cigarettes who visited dental clinic. Methods: This study is researched 179 people as smoker which visited 2 dental hospital and 3 dental clinic in Gwangju Metropolitan City using questionnaire survey from September 27, 2017 to October 24, 2017. The data was analyzed as frequency, percentage, average, standard deviation, chi-square test, t-test, logistic regression using by SPSS version 24.0 statistics program. Results: Look over the analyze logistic regression using simple analysis result which percentage of relate lower than 0.1 based on answer which electronic cigarettes is no effect as use cessation aid, effective is 5.75 times higher. In case answer the effective as use cessation aid, they relate on use electronic cigarette (95% confidence interval, 95% CI=1.57-21.03). Based on no stress during everyday life, stressed is 3.53 times higher than unstressed and relate on intent to use electronic cigarettes (95% CI=1.25-9.98). Also based on answered no effect as use cessation aid is 6.62 times higher than effective as use cessation aid and related to intent of use electronic cigarette (95% CI=1.58-27.66). Based on doesn’t heard about electronic cigarettes are legally classified cigarettes, heard is 3.31 times higher than doesn’t heard and related on intent of use electronic cigarettes (95% CI=1.26-8.67). Conclusions: In this study, if help to get a correct recognition of electronic cigarettes and use cessation education to use people who visited dental clinic can be possible effective use cessation.

응급구조(학)과 학생들의 윤리적 가치관 관련 요인

김예림,류소연,박종,한미아,Kim, Ye-Rim,Ryu, So-Yeon,Park, Jong,Han, Mi-Ah 한국응급구조학회 2018 한국응급구조학회지 Vol.22 No.2

Purpose: This study was performed to investigate the level of ethical values and its related factors among some paramedic students. Methods: The subjects of this study were 480 paramedic students from five universities located in G-metropolitan city and J province. Data were collected using a self-administered questionnaire and analyzed using t-test, ANOVA, Pearson's correlations, and multiple regression analysis. Results: The mean scores of level of ethical values, academic self-efficacy and self-esteem were $3.70{\pm}0.45$, $3.15{\pm}0.42$ and $3.60{\pm}0.70$, respectively. In the correlation analysis, ethical value level was significantly positively correlated with self-esteem (r=.195, p< .001) and academic self-efficacy (r=.156, p= .001), of domains in academic self-efficacy, self-regulation efficacy (r=.230, p< .001) and confidence (r=.105, p= .022). In multiple regression analysis, self-esteem (${\beta}=.163$, p= .026), task ease preferences (${\beta}=-.350$, p< .001) and confidence (${\beta}=.403$, p< .001) were significantly related to ethical value levels. In addition, subjects willing to participate in the bioethics education showed higher relevance to ethical values than indifferent subjects (${\beta}=2.751$, p= .003). Conclusion: Concrete and systematic education will be needed in order to foster the establishment of ethical values of the paramedic students. Additionally, to fulfill their roles and obligations as emergency medical technicians, in the field, various educational curricula based on simulated cases in the university should be introduced.