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      • KCI등재

        서비스 구성요소가 고객 만족도 및 재방문에 미치는 영향 -부산지역 미용실 소비자를 대상으로-

        류선이 ( Sun Yi Ryu ),박옥련 ( Ok Lyun Park ) 한국미용학회 2009 한국미용학회지 Vol.15 No.4

        This study analyzed the effect that service quality, display, and the use of information source of the clients have on consumer satisfaction and revisit. The results are as follows: it appeared that service quality factor, display factor, and the use of information source factor as independent variables had high explanation and significant effect on consumer satisfaction and revisit as dependent variables. It appeared that human service out of the service qualities had the highest effect on consumer satisfaction. And it appeared that technical service had the highest effect on revisit. First of all, atmosphere out of the display factors had high effect on consumer satisfaction and revisit, and had the second effect on the plan of lighting. It appeared that the use of information source out of human information had the highest effect on consumer satisfaction and revisit. Also it was analyzed that consumer satisfaction had high explanation and significant effect on revisit. This study intend to provide the management of beauty shop with useful information on the basis of the results above.

      • KCI등재

        라이프스타일에 따른 서비스품질 및 디스플레이 소비 욕구 차이에 관한 연구 -미용실 소비자를 대상으로-

        류선이 ( Sun Yi Ryu ),박옥련 ( Ok Lyun Park ) 한국미용학회 2009 한국미용학회지 Vol.15 No.2

        This study classified 4 life-style groups through clustering analysis with analyzing and extracting life-style factors of the clients. We named group 1 to the conservative type of pursuing appearance, group 2 to the type of pursuing appearance, group 3 to the type of indifference, and group 4 to the type of pursuing personality. The results of analysis are as follows: Firstly, the conservative type of pursuing appearance and the type of pursuing appearance appeared as groups which have characteristic of using appropriately service quality and display construction. Secondly, the type of indifference appeared as group which has characteristic of using negatively of them. And thirdly, the type of pursuing personality appeared as group which has characteristic of using positively of them. The difference of investigating objects` characteristics according to life-style group was analyzed, and the results are as follows: gender, the existence of marriage, job, total income a month, and spending money a month appeared to be significant. Age and educational level appeared not to be significant. We are intending to provide practical information use of beauty shop clients with information of research results above.

      • KCI등재후보

        미용실 소비자의 라이프스타일에 따른 서비스품질 디스플레이, 정보원활용에 대한 상관관계

        류선이(Ryu Sun Yi),박옥련(Park Ok Lyun) 한국인체예술학회 2009 한국인체미용예술학회지 Vol.10 No.1

        The objectives of the study were to analyze the factors of Lifestyle, service quality, display, utilization of informants; to examine the correlation between life style and service quality, between lifestyle and display, and between display and the source of information. Customer's various lifestyles were classified as price-oriented, trend oriented, brand oriented, convenience oriented, appearance oriented. This classification was meaningful and showed high level of reliability. Significant correlation between the lifestyle and service quality was found specially in appearance oriented customers. It was also found that the correlation between lifestyle and display is significant in appearance oriented customers. The correlation analysis between the display and utilization of informants showed that there was significant correlation in personal service, external/internal service, technical service, after service under human resource information factor. I hope the above mentioned findings of the study would be utilized for providing information for beauty shop customers

      • KCI등재
      • KCI등재

        Interleukin-17이 배양된 류마티스 관절염 활막세포에서 Matrix Metalloproteinase-3의 생성에 미치는 영향

        류선 ( Sun Ryu ),김성일 ( Sung Il Kim ) 대한류마티스학회 2004 대한류마티스학회지 Vol.11 No.1

        Objective: To investigate the effect of interleukin-17 (IL-17) on the production of matrix metalloproteinase-3 (MMP-3) and the expression of MMP-3 mRNA in rheumatoid arthritis synoviocytes. Methods: Fibroblast-like synovial cells (FLS) were prepared from the synovial tissues of rheumatoid arthritis patients and cultured in the presence of various concentration of IL-17. The production of MMP-3 and expression of MMP-3 mRNA were determined by sandwitch ELISA and real-time quantitative RT-PCR. Results: In ELISA, stimulation of FLS by IL-17 with 5, 10, 20, 40 ng/mL concentrations increased the production of MMP-3 by 2.7, 2.9, 3.1, 3.6 fold after 24 hours and 9.9, 10, 11, 12 fold after 48 hours over the constitutive levels of unstimulated FLS. In real-time quantitative RT-PCR, stimulation of FLS by IL-17 with 5, 10, 20, 40 ng/mL concentrations increased the MMP-3/β-actin mRNA ratio by 3.2, 5.7, 9.9, 30.5 fold after 24 hours over the constitutive levels of unstimulated FLS.

      • KCI등재

        류마티스 관절염 동물 모델에서 활막의 RANKL/OPG mRNA 발현 비율 및 IL-17의 효과

        이준희 ( Jun Hee Lee ),김근태 ( Geun Tae Kim ),류선 ( Sun Ryu ),김주인 ( Ju In Kim ),백승훈 ( Seung Hoon Baek ),김성일 ( Sung Il Kim ) 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.2

        Objective: To investigate the synovial mRNA expression of receptor activator of NFκB (RANK), RANK ligand (RANKL), osteoprotegerin (OPG) and RANKL/OPG mRNA expression ratio, and to evaluate the effects of IL-17 in experimental rheumatoid arthritis (RA) model. Methods: After induction of collagen-induced arthritis (CIA) by type II collagen in DBA1 mice, mice were anesthetized at day 28 and a small aperture in the skin of the knee was performed. Mice, in which arthritis of knee was present, were selected and divided into 3 groups, and phosphate-buffered saline (PBS group), IL-17 (IL-17 group) or anti-IL-17 monoclonal antibody (anti-IL-17 group) was injected to both knee joint at day 28 and 32. At day 35, mice were sacrificed and synovium of knee joints were isolated. Synovial mRNA expression of RANKL, RANK and OPG was assessed by real-time RT-PCR and immunohistochemical stain. Results: Synovial RANKL and RANK mRNA expressions were significantly different among IL-17, PBS, anti-IL-17 and normal group (IL-17>PBS>anti-IL-17>normal group), and synovial OPG mRNA expressions in PBS, IL-17 and anti-IL-17 group were significantly high than those in normal group, however, there was no significant difference among IL-17, PBS and anti-IL-17 group. RANKL/OPG mRNA ratio was significantly different among these groups (IL-17>PBS>anti-IL-17>normal group). In immunohistochemical stain, RANKL, RANK and OPG-positive cells were expressed at synovium. Conclusion: Synovial RANKL/OPG mRNA ratio was enhanced in CIA, and IL-17 induced higher RANKL/OPG ratio in the synovium of CIA, which was blocked by anti-IL-17 antibody. These results suggest that RANKL/OPG mRNA ratio play an important roles on bone destruction, and IL-17 may be actively involved in bone destruction by enhancing RANKL/OPG ratio in CIA model.

      • KCI등재

        류마티스 관절염 동물 모델에서 Toll-Like Receptors의 발현

        이준희 ( Jun Hee Lee ),이수봉 ( Soo Bong Lee ),김근태 ( Geun Tae Kim ),류선 ( Sun Ryu ),김주인 ( Ju In Kim ),이선희 ( Sun Hee Lee ),김성일 ( Sung Il Kim ) 대한류마티스학회 2006 대한류마티스학회지 Vol.13 No.2

        Objective: To evaluate the expression of Toll-like receptor (TLR) 2, 4 and 9 and investigate the effects of IL-17 on the expression of TLRs in experimental rheumatoid arthritis (RA) model. Methods: After induction of collagen-induced arthritis (CIA) by type II collagen in DBA1 mice, phosphate-buffered saline (PBS, PBS group) or IL-17 (IL-17 group) was injected to both knee joint at day 28 and 32. At day 35, mice were sacrificed and knee joints were isolated. Synovial mRNA expressions of TLR-2, 4 and 9 determined by real-time RT-PCR were compared among normal DBA1 mice (normal group), PBS and IL-17 group. Results: Synovial TLR-2, 4, and 9 mRNA expressions of IL-17 and PBS group were significantly higher than normal group, and those of IL-17 group were higher than PBS group. Conclusion: Synovial TLR-2, 4 and 9 expression was enhanced in CIA and up-regulated by local overexpression of IL-17. These results suggest that TLRs play a roles on CIA and IL-17 induced aggravation of arthritis in CIA.

      • KCI등재후보

        반코마이신 내성 장내구균 분리 환자에서 황색포도알균의 내성

        김동욱,신선혜,김혜진,류선,이선희,장철훈,김영대,곽임수 대한감염학회 2004 감염과 화학요법 Vol.36 No.1

        목적 : Vancomycin-resistant enterococci (VRE)로부터 S. aureus로의 vacomycin 내성 유전자의 전파는 오래전부터 예견되어져 왔으며 큰 걱정거리로 남아있다. 최근에 vanA 유전자를 가지고 있는 vancomycin-resistant S. aureus 2주가 미국에서 분리되었다. 이 연구의 목적은 VRE를 보균하고 있는 환자들에서 S. aureus 보균양상과 항균제 내성을 알아보는데 그 목적이 있다. 재료 및 방법 : 2001년 1월부터 2001년 12월까지 부산대학교병원에 입원하였던 환자들 중 임상검체에서 VRE가 분리된 환자 7명과 2001년 9월부터 12월까지 외과 중 환자실에 입원하였던 환자들 중 VRE 감시배양을 시행하였던 20명의 환자들을 대상으로 하였다. 환자들은 전비공, 액와부, 회음부, 직장에서 매주 면봉으로 검체를 채취하였다. 선별배지에서 검체를 배양하여 S. aureus를 분리하였고 원판 확산법을 이용하여 methicillin 감수성을 측정하였다. Broth microdilution 법으로 vancomycin MIC를 측정하였다. 결과 : 총 27명에서 73회의 방문과 292회의 배양이 시행되었으며 총 67주의 S. aureus가 분리되었다. 이중 64주(95.5%)가 methicillin 내성이었다. 전비공 MRSA 보균율은 VRE를 보균하고 있었던 환자는 19명 중 11명(58%)에서, VRE를 보균하지 않았던 환자는 8명 중 3명(37.5%)으로 VRE 보균자에서 보균율이 더 높았다. 총 64주의 MRSA의 vancomycin MIC의 분포는 0.5-2㎍/mL였으며 2㎍/mL를 초과하는 균주는 발견되지 않았다. 64주 중 vancomycin MIC가 1㎍/mL인 균주가 54주(84.4%)로 가장 많았으며 2㎍/mL 6주(9.4%), 0.5㎍/mL 4주(6.3%)의 순이었다. 결론 : VRE 환자에서 S. aureus의 보균율은 비보균자 보다 높았으며 분리된 균주들은 대부분 MRSA였다. VRSA 균주는 발견되지 않았다. Background : The transfer of vancomycin resistance from vancomycin-resistant enterococci (VRE) to Staphylococcus aureus has been predicted. The purpose of this study is to determine the prevalence and antibiotics resistance of S. aureus among patients colonized with VRE. Methods : Between January 2001 and December 2001, a prospective study was performed at Pusan National University Hospital on 27 patients. Surveillance swabs from nasal cavity, axilla, perineum, and rectum were obtained at weekly intervals. Methicillin susceptability of S. aureus was determined by oxacillin disk diffusion test and minimum inhibitory concentration (MIC) for vancomycin by microdilution broth test. Results : Total of 292 swab cultures were performed and 67 S. aureus isolates were collected. 64 isolates (95.5%) were resistant to methicillin. The prevalence of nasal MRSA carrier in 19 patients colonized with VRE was higher than that in 8 patients not colonized with VRE (58% vs. 37.5%). In 64 MRSA isolates, MIC (㎍/mL) for vancomycin ranged from 0.5 to 2. No isolates with MIC >2 ㎍/mL were observed. MIC of 1 ㎍/mL was shown (observed) in 54 isolates, 2 ㎍/mL in 6 isolates, and 0.5 ㎍/mL in 4 isolates. Conclusion : The prevalence of S. aureus with colonization of VRE is higher than that without colonization of VRE. Most of S. aureus isolates were resistant to methicillin. VRSA isolates were not observed.

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