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후두기관지폐렴으로 진단된 소아 환자들의 임상 양상과 원인: 크룹 환아와의 비교
김은진 ( Eun Jin Kim ),남혜나 ( Hyena Nam ),선용한 ( Yong Han Sun ),차한 ( Hann Tchah ),류일 ( Eell Ryoo ),조혜경 ( Hye Kyung Cho ),조혜정 ( Hye Jung Cho ),손동우 ( Dong Woo Son ) 대한천식알레르기학회(구 대한알레르기학회) 2017 Allergy Asthma & Respiratory Disease Vol.5 No.5
Purpose: Croup, a common childhood respiratory illness with various severities, has many unanswered questions. Laryngotracheo-bronchopneumonitis (LTBP) is a disease entity considered to be an extension of croup to the lower respiratory tract. The object of this study was to compare epidemiology, clinical characteristics, and viral etiologic spectrum between croup and LTBP. Methods: Patients hospitalized with croup at Gachon University Gil Hospital from January 2010 to April 2016 were recruited. LTBP was defined as pneumonia confirmed on radiographs of patients with croup. Clinical findings and demographic data were re-viewed of patients whose nasopharyngeal swabs were done for viral analysis. Results: A total of 371 patients with only croup and 63 patients with LTBP were included. Croup was found to be significantly associ-ated with parainfluenza virus type 1 (P=0.006). LTBP was related to parainfluenza virus type 3, respiratory syncytial virus, and hu-man bocavirus (P=0.001, P=0.030, and P=0.019, respectively). The duration of fever was longer in patients with LTBP than in those with croup (3.87±1.85 days vs. 2.86±1.80 days, P<0.001). Conclusion: Specific etiologic viruses might be associated with the progression from croup to LTBP. Pronged fever is also associated with progression from croup to LTBP. (Allergy Asthma Respir Dis 2017;5:274-279)