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비만한 성인 남자에서 혈중 렙틴과 비알코올성 지방간과의 관계
이은상(Eun Sang Lee),이돈행(Don Haeng Lee),김승연(Seung Youn Kim),김진영(Jin Young Kim),김화숙(Wha Sook Kim),이훈재(Hoon Jae Lee),최원(Won Choi),김범수(Pum Soo Kim),김형길(Hyung Gil Kim),김영수(Young Soo Kim) 대한내과학회 2001 대한내과학회지 Vol.61 No.6
N/A Background: The non-alcoholic fatty liver is characterised by accumulation of triglycerides within liver parenchymal cells without intake of alcohol. Leptin is produced by peripheral adipose cells and it's blood concentrations are positively correlated with blood insulin levels, independent of body mass index. Non-alcoholic fatty liver is associated with insulin resistance and hyperinsulinemia even in lean subjects. Therefore, we aimed to elucidate whether hyperleptinemia is associated with non-alcoholic fatty liver, independent of age and obesity. Methods : The age, weight, BMI and blood laboratory data such as LFT, lipid profiles, insulin, and leptin were analyzed on 26 control subjects and 30 non-alcoholic fatty liver subjects with BMI above 25 kg/㎡ in male adults. Results: There was no significant difference in their age, height, weight, and BMI between normal control group and non-alcoholic fatty liver group. But, blood triglyceride, leptin, and insulin level of patients with non-alcoholic fatty liver were significantly higher than those of normal control group. Conclusion: Blood leptin levels of non-alcoholic fatty liver group were significantly higher than that of control group. Thus, high circulating leptin concentrations may play a role in the pathogenesis of non-alcoholic fatty liver, regardless of age and obesity.(Korean J Med 61:634-640, 2001)
김화숙,김범수,정석,심미란,양문희,김성연,권계숙,조현근,김형길,신용운,김영수,이돈행 대한내과학회 2002 대한내과학회지 Vol.62 No.6
Congenital solitary nonparasitic cysts of the liver are rare condition in all age groups. Since 1856, only approximately 900 cases having been reported in the world literature. Epidermoid cysts of the liver are extremely rare type of congenital nonparasitic hepatic cysts, characterized by a fibrous wall entirely lined with stratified squamous epithelium, but lacking hair or skin appendages. This condition has yet to be reported in Korea. Because they have a potential for malignant transformation, it is important to totally resect the epidermoid cyst of the liver. Recently, we experienced a case of 44-year-old female patient with epidermoid cyst of the liver, which condition was complicated by a secondary infection. For this patient, an enucleation of entire cyst was performed. Given the rarity of this case, the following is a report of this case and a review of the relevant literature.
李醇熙,金和淑,金洋一,李學重 中央醫學社 1974 中央醫學 Vol.26 No.1
Statistical studies were made on the arrhythrnias found in 1,763 electrocardiographic tracings taken at the National Medical Center from January to October 1973. The results were as follows: 1) The over-all incidence of various arrhythmias was 33.02 per cent which consisted of disturbance in impulse formation 26.21 per cent and conduction disturbance 6.81 per cent. The frequent arrhythmia was abnormality oftsinus rhythm 13.96 per cent. 2) The incidences of arrhythmias except for sinus rhythm abnormalities were auricular fibrillation 5.84 per cent, ventricular pre-:nature beat 4.42 per cent, right bundle branch block 2.72 per cent, atrial premature beat 0. 91 per cent, left anterior hemiblock 0. 91 percent, idionodal rhythm 0.51 percent, left bundle branch block 0.45 percent, intraventricular conduction defect 0.45 per cent, nodal escaped beat 0. 17 per cent, second degree A-V block 0. 17 per cent, S-A block 0. 17 per cent, supraventricular tachycardia 0. 11 per cent, third degree A-V block 0. 11 per cent, A-V dissociation 0. 11 per cent, aberrant conjunction 0. 11 per cent, W-P-W syndrome 0. 11 per cent, nodal premature beat 0.03 per cent and ventricular tachycardia 0. 06 per cent of the 1, 763 tracings. 3) Arrhythmias were found in 75 percent of 45 patients with coronary heart disease, 68.85 per cent of 108 with valvular heart disease, 46.15 per cent of 13 with pericarditis, 33.33 per cent of 15 with corpulmonale, 27.42 per cent of 197 with hypertension or hypertensive heart disease and 25 Per-,Cent of 24 with congenital heart disease. An 47.45 per cent incidence of arrhythmip in the cardiovasculr disease group, 7.93 per cent in the non-cardiovascular group and 6.32 per cent in apparently healthy group were observed. The most frequent underlying disease of arrhythmias -in the non-cardiovascular group was renal disease (12.15 per cent incidence). 4). Cardiovascular diseases were ,observed 4n 74.75 per cent of all patients with auricular fibrillation and non-cardiovascular diseases in 25.25, percent. Mitral valvular disease was seen in 65.9 per cent of patients with auricular fibrillation which was cause by organic heart diseases. 5) Left anterior hemiblock occurred most frequently after 40 years of age (in 12 of 16 cases). The most common causes of the hemiblock were myocardial infarction and coronary heart disease after 40 and mitral valvular disease before 40 years of age.