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      • KCI등재
      • KCI등재

        일개 농촌지역 저소득층 당뇨병환자의 관리 상태

        김혜연,윤우준,신민호,권순석,안혜란,최성우,이영훈,조동혁,이정애,Kim, Hye-Yeon,Yun, Woo-Jun,Shin, Min-Ho,Kweon, Sun-Seong,Ahn, Hye-Ran,Choi, Seong-Woo,Lee, Young-Hoon,Cho, Dong-Hyeok,Rhee, Jung-Ae 대한예방의학회 2009 예방의학회지 Vol.42 No.5

        Objectives : Knowledge about the management status of diabetic melitus (DM) is essential to improve diabetic management. Moreover, low income is associated with poor adherence to treatment and increased mortality. This study was performed to evaluate the management status of DM in low-income patients in a rural area. Methods : We enrolled 370 patients with type 2 DM living in Gokseong county, JeollaNamdo. A well-trained examiner measured the height, weight, waist circumference, blood pressure, total cholesterol, triglyceride, high density lipoprotein cholesterol, fasting blood sugar and glycosylated hemoglobin (HbA1c) levels. Carotid ultrasonography was used to measure carotid artery carotid artery intima media thickness (IMT) and plaque. anklebrachial index (ABI) was used to evaluate peripheral artery disease. A fundoscopic examination was performed to evaluate diabetic retinopathy. A history of diabetes complications and health-related questionnaires were also completed. Results : The age of diabetic subjects was 68.7$\pm$8.7 years and the duration of diabetes was 8.9$\pm$8.2 years. Most (63.5%) had hypertension, and 45.7% had triglycerides below 150 mg/dl, 38.1% had low density lipoprotein cholesterol (LDL) cholesterol below 100 mg/dl, 48.7% had urine albumin to creatinine ratio (UACR) below 30 mg/g. Less than half (45.9%) achieved the goal of HbA1c less than 7% suggested by the American Diabetes Association (ADA). 10.6% had peripheral vascular disease, 11.9% had retinopathy, and 60.8% had chronic kidney disease. Conclusions : DM management in low income patients is very poor and requires further work to improve.

      • KCI등재
      • KCI등재

        자궁경부암에서 Cdc25A, Cdc25B 및 Cdc25C의 발현

        김혜연 ( Hye Yeon Kim ),김재욱 ( Jae Wook Kim ),김세광 ( Sei Kwang Kim ),김영태 ( Young Tae Kim ),김재훈 ( Jae Hoon Kim ),김성훈 ( Sung Hoon Kim ),김상운 ( Sang Wun Kim ),윤보성 ( Bo Sung Yoon ),남은지 ( Eun Ji Nam ),조혜진 ( Hye 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.10

        목적: 본 연구는 자궁경부암에서 세포주기 조절인자인 cell division cycle (Cdc) 25A, Cdc25B 및 Cdc25C 발현 양상을 정량적으로 측정하여 이들이 자궁경부암의 발암과정에서 어떠한 역할을 하는지를 규명하며 아울러, 자궁경부암의 여러 다른 임상적 및 병리학적 예후 인자와 상관관계가 있는지를 연구하고자 하였다. 연구 방법: 본원 산부인과에서 2000년 2월부터 2005년 3월까지 수술적 치료를 받은 환자를 대상으로 하여 신선 자궁경부 조직을 얻었다. 역전사 중합요소 연쇄 반응과 Western blot analysis를 이용하여 각각 Cdc25A, Cdc25B 및 Cdc25C의 mRNA와 단백질 발현 양상을 확인하였다. 결과: 자궁경부암 조직에서의 Cdc25A, Cdc25B 및 Cdc25C의 mRNA 발현은 정상 자궁경부 조직보다 모두 통계학적으로 유의하게 높았으며 (p=0.02, 0.01, 0.02), Cdc25A, Cdc25B 및 Cdc25C의 단백질 발현 양상도 자궁경부암 조직에서 정상 자궁경부 조직에 비해 모두 통계학적으로 유의하게 높은 결과를 보였다 (p=0.01, 0.02, 0.01). 또한 자궁경부암에서의 Cdc25A, Cdc25B 및 Cdc25C의 mRNA 발현과 단백질 발현을 임상적 및 병리학적 예후 인자들에 따라 비교한 결과 환자의 연령과 Cdc25B mRNA 발현 (p=0.03), 세포 형태와 Cdc25C mRNA 발현 (p=0.04) 사이에서는 통계학적으로 유의한 상관관계를 보였으나 그 외의 인자들인 세포아형태, 혈청내 squamous cell carcinoma antigen (SCC Ag) 수치, 유세포 분석법을 통한 DNA flow cytometry 결과, 림프절 전이, 림프혈관 침범, 인유두종 바이러스 감염 등과는 통계학적으로 유의한 상관 관계를 보이지 않았다. 결론: 본 연구 결과에 따르면 Cdc25A, Cdc25B 및 Cdc25C가 대조군인 정상 자궁경부 조직에 비해 자궁경부암 조직에서 통계학적으로 유의하게 높게 발현됨을 확인할 수 있었다. 따라서, 자궁경부암의 발생기전에 Cdc25A, Cdc25B 및 Cdc25C가 중요한 역할을 할 가능성을 제시하였다. 또한 Cdc25A, Cdc25B 및 Cdc25C의 mRNA와 단백질 발현은 환자의 연령이 50세 이상인 경우에 Cdc25B mRNA 발현이 유의하게 높았으며 (p=0.03), 세포형태에 따라 분류하였을 때 편평상피세포암에서 Cdc25C mRNA 발현이 통계학적으로 유의하게 높았다 (p=0.04). 그러나, 다른 예후 인자들과는 통계학적으로 유의한 상관관계를 보이지 않았다. 향후 Cdc25A, Cdc25B 및 Cdc25C가 자궁경부암의 유용한 예후 인자로 사용되기 위해서는 향후 생존율과 연관된 연구가 추가로 뒷받침되어야 할 것으로 생각된다. Objective: This study was undertaken to quantitatively detect Cdc25A, Cdc25B and Cdc25C in cervical carcinoma and determine the relationship between the expression of mRNA and protein of cell division cycle (Cdc)25 phosphatase and various clinicopathologic prognostic factors of cervical carcinoma. Methods: 39 patients diagnosed with cervical carcinoma between February 2000 to March 2005 and 10 patients with benign gynecologic disease were enrolled in this study. A reverse transcriptase-polymerase chain reaction (RT-PCR) and Western blot analysis were used to analyze the expression of Cdc25 phosphatase mRNA and protein in fresh invasive cervical cancer tissue and normal cervix tissue. Results: The mRNA expressions of Cdc25A, Cdc25B and Cdc25C in the cancer tissues were significantly greater than in the control (p=0.02, 0.01, 0.02), respectively. A Western blot analysis yielded same results (p=0.01, 0.02, 0.01). There were also significant relationships between the age and the Cdc25B mRNA expression (p=0.03), between the cell type and the Cdc25C mRNA expression (p=0.04). However, other clinicopathologic prognostic factors including stage, subtype, SCC Ag level, DNA flow cytometry, lymph node metastasis, lymphovascular space invasion and HPV positivity were not statistically significant. Conclusion: Our results show that Cdc25A, Cdc25B and Cdc25C expression levels were significantly greater in cervical cancer patient group than in those of control group. Thus Cdc25 phosphatase might play an important role in carcinogenesis of cervical carcinoma. Further studies based on the correlation between Cdc25 phosphatase and survival rate would be need to support Cdc25 phosphatase as a prognostic factor of cervical carcinoma.

      • KCI등재

        건강가정 교육프로그램 개발에 관한 연구: 최소치 향상 원리의 팀 성과행동 코칭모델의 적용과 평가

        김혜연 ( Hye Yeon Kim ) 대한가정학회 2013 Human Ecology Research(HER) Vol.51 No.6

        This study aims to develop an educational program for healthy families using Christoph`s team performance coaching (TPC) model and evaluate the program by program participant feedback. The educational program is unique in terms of helping the program participants measure the health level of their families, setting goals for the health improvement of their families based upon minimum family performance and seeking ways to achieve these goals. The educational program was designed as 3-hour-course for the convenience of implementing education and recruiting participants. The overall program was based on the characteristics and principles of coaching. Those with a master`s degree or above and professional coaches were recruited as instructors. The first workshop for the instructors was conducted in 2 sessions, for 12 hours each (Dec 29-30, 2010 and Feb 12-13, 2011) and the second workshop was conducted Mar 25-26, 2011, for 12 hours. During the workshop for the instructors, the final education program was completed based upon the instructors` impression and evaluation. 8 instructors conducted the educational programs in educational institutions and facilities across the nation. The results of the program evaluated by 419 adults of education participants demonstrated the applicability of Christoph`s team performance coaching model to the educational program for healthy family and its effects. If various educational programs with flexible education hours and content according to the needs of subject groups are developed, this educational program can be used as a basic educational program for in-depth education and further service for the improvement of family health.

      • KCI등재

        골반 장기 탈출증 환자에서 각 연령별에 따른 수술 후 합병증 비교

        김혜연 ( Hye Yeon Kim ),전명재 ( Myung Jae Jeon ),정다정 ( Da Jung Chung ),김세광 ( Sei Kwang Kim ),김재욱 ( Jae Wook Kim ),배상욱 ( Sang Wook Bai ) 대한산부인과학회 2007 Obstetrics & Gynecology Science Vol.50 No.11

        목적: 본 연구는 골반 장기 탈출증 환자에서 연령이 증가함에 따라 수술 후 퇴원까지의 합병증이 증가하는지에 대해 알아보고자 하였다. 연구 대상 및 방법: 1999년 3월부터 2006년 2월까지 본원 산부인과에서 골반 장기 탈출증으로 수술을 시행 받은 환자 중 기록 분석이 가능한 322명의 환자를 대상으로 하였다. 40대부터 80대까지 각 연령에 따른 환자들의 특성과 재원일수, 신체질량지수, 기왕 수술력, 수술 시간, 수술 방법, 마취 방법, 기저 질환, 수술 전 후의 혈색소 차이와 수술 후 합병증에 대해 후향적으로 조사하여 비교 분석하였다. 결과: 연령별로는 40-49세가 35명 (10.9%), 50-59세 97명 (30.1%)이었고, 60-69세가 123명 (38.2%)으로 가장 많았으며, 70-79세가 64명 (19.9%), 80세 이상은 3명 (0.9%)으로 가장 적었다. 각 연령군 간에는 분만력에서만 유의한 상관관계를 보였으며, 병기, 신체질량지수, 기왕 수술력, 수술 시간, 수술 종류, 마취 종류, 기저 질환, 수술 전후의 혈색소 차이는 통계학적으로 유의한 상관 관계가 없었다. 또한 발열, 빈혈, 수혈 여부, 혈종, 장마비, 장폐색, 상처 감염, 상처 열개, 하부 요료계 감염, 폐렴, 골반 감염, 심부전, 심근 경색, 폐부종, 폐색전 등의 수술 후 합병증 발생에서 각 연령군 간에 유의한 차이를 보이지 않았다. 결론: 골반 장기 탈출증 환자에서 수술 후 합병증의 발생은 환자의 연령과 연관성이 없는 것으로 사료된다. Objective: The purpose of this study was to estimate the effect of age on the risk of in-hospital surgical morbidity in patients with pelvic organ prolapse (POP). Methods: Of the women aged 40 years and older who underwent surgical correction of POP at this institution from March 1999 to February 2006, 322 had medical records that could be analyzed. These patients were grouped according to decade of age and assessed according to a set of characteristics and postsurgical complications. Results: There were 35 patients between 40 to 49 years of age, 97 between 50 to 59 years, 123 between 60 and 69 years, 64 between 70 to 79 years and 3 patients were 80 years or older. There were no differences between age groups regarding the following variables: stage, delivery history, BMI, previous surgical history, underlying medical disease, duration of hospital stay, operation time, type of operation and anesthesia, difference of preoperative and postoperative hemoglobin level. There were differences only for parity. Also, between each age group, no statistical differences were noted in postoperative complications. Conclusion: The risk of in-hospital surgical morbidity in patients with POP was not related to the age of the patients.

      • KCI등재
      • KCI등재

        경량패널로 마감된 사회체육시설의 음향성능 개선에 따른 주관적 반응의 변화

        김혜연(Hye-Yeon Kim),박정수(Jeong-Soo Park),김재수(Jae-Soo Kim) 한국생활환경학회 2015 한국생활환경학회지 Vol.22 No.2

        The recent improvement in the quality of living has led to greater interest in health and to constant establishment of community sports facilities which are not dependent on seasons or weather. However, lightweight panel, which is convenient and cheap, has been used as a finished material for most of the existing community sports facilities, which, thus, have acoustic defect with excessive echoes. Although acoustic simulation is used to change finished material and improve acoustic performance, there are significant differences from subjective satisfaction among people after the improvement. From this perspective, this study aimed to conduct a psycho-acoustic experiment to see the variation in subjective responses among people on the basis of the data concerning acoustic performance in community sports facilities finished with lightweight panel. After improving acoustic performance in terms of optimum reverberation time in community sports facilities where acoustic defect was found, such evaluation vocabularies as “reverberant”, “loudness”, and “diffusion” got lower responses while “intimacy”, “definition”, “clarity”, “warmth”, and “balance” got higher responses. It was therefore found that subjective responses could be improved along with the improved acoustic performance in community sports facilities with the problem of excessive echoes. It is expected that this study will be able to provide useful data for improving acoustic performance in similar community sports facilities.

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