지백지황탕(知栢地黃湯)으로 호전된 진행성 색소성 자반병의 한방치료 1례

김현정,김태연,이창원,김창환,Kim, Hyun-Jung,Kim, Tae-Yeon,Lee, Chang-Won,Kim, Chang-Hwan 대한한방안이비인후피부과학회 2013 한방안이비인후피부과학회지 Vol.26 No.2

Objective : The purpose of this report is to know the effect of Jibaekjihwang-tang(知栢地黃湯) on progressive pigmented purpuric dermatosis. Methods : We experienced one case of progressive pigmented purpuric dermatosis treated with Jibaekjihwang-tang(知栢地黃湯). We used visual analogue scale(VAS). Results : After the treatment the grade of VAS was decreased and purpuras, pruritus and dryness of skin were disappeared. Conslusion : Jibaekjihwang-tang(知栢地黃湯) can be used on the treatment of progressive pigmented purpuric dermatosis.

알코올을 처리한 HepG2 세포에서 참죽나무 잎 추출물의 세포 보호 및 항산화 효과

김현정,조수연,김정봉,김헌웅,최정숙,장환희,Kim, Hyun-Jeong,Cho, Su-Yeon,Kim, Jung-Bong,Kim, Heon-Woong,Choe, Jeong-Sook,Jang, Hwan-Hee 한국식품영양학회 2018 韓國食品營養學會誌 Vol.31 No.4

All the parts of the Cedrela sinensis A. Juss., including the seeds, roots, and leaves, have been known to exert medicinal effects. The C. sinensis and its major compound, quercetin, were previously reported to exhibit the anti-inflammatory and anti-oxidative activities. However, the hepatoprotective effects of the C. sinensis leaves against the alcohol-induced oxidative stress in the HepG2 cells have not been studied. In this study, we investigated the antioxidant activities and analyzed the flavonoid contents of the C. sinensis-leaf extract (CE). The total flavonoid contents of the CE is 1,874.5 mg/100 g dry weight (DW), while the total quercetin 3-O-rhamnoside (quercitrin) contents, which was identified as the major flavonol in the CE, is 1,456.0 mg/100 g DW. In the ethanol-stimulated HepG2 cells, the CE effectively prevented the cytotoxic effect and increased the gene expression of the antioxidant enzymes, such as the heme oxygenase-1 (HO-1) and the glutathion peroxide (GPx). The level of the reactive oxygen species (ROS) production was significantly decreased in the CE-treated HepG2 cells. In conclusion, the C. sinensis extract suppressed the alcohol-induced oxidative stress in the HepG2 cells via the induced GPx and HO-1 gene expressions. It is expected the CE positive effects will likely be attributed to the flavonoids, like the quercetin, within the CE.

정적지능(情績知能)에 관한 문헌적(文獻的) 고찰(考察)

김현정,김장현,Kim, Hyun-Jung,Kim, Jang-Hyun 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.2

Objectives The purpose of this study is to determine oriental medical concept of emotional intelligence, and to develop the ways of treatment. Methods We investigated the literature of the oriental and western medicine about an emotional intelligence. Results Regarding an emotional intelligence from the oriental medicine, it will follow in attributes of five elements(五行), five emotions(五志), seven passions(七情). Due to the five emotions and seven passions will take to control themselves with following the principle of poles at interinhibition, and intergeneration among the five phases. There is a possibility of trying to apply in reflection control of emotion(partIV). Five emotions(五志), depression theories(鬱症), and a control of theories of seven passions(七情調節) will be applied an emotional stability and an emotional control. Conclusions This study showed that oriental medicine has more merits better than western medicine about emotional intelligence, because oriental medicine consider that the body and mental is an inseparable relation. The further study is necessary with the concept formulation and for a historical investigation about an emotional intelligence.

정서지능(情緖知能)에 관한 문헌적(文獻的) 고찰(考察)

김현정,김장현,Kim, Hyun-Jung,Kim, Jang-Hyun 동국대학교 한의학연구소 2008 東國韓醫學硏究所論文集 Vol.10 No.-

Objective: The purpose of this study is to determine oriental medical concept of emotional intelligence, and to develop the ways of treatment. Methods: We investigated the literature of the oriental and western medicine about an emotional intelligence. Results: Regarding an emotional intelligence from the oriental medicine, it will follow in attributes of five elements(五行), five emotions(五志), seven passions(七情). Due to the five emotions and seven passions will take to control themselves with following the principle of poles at interinhibition, and intergeneration among the five phases. There is a possibility of trying to apply in reflection control of emotion(partIV). Five emotions(五志), depression theories(鬱症), and a control of theories of seven passions(七情調節) will be applied an emotional stability and an emotional control. Conclusion: This study showed that oriental medicine has more merits better than western medicine about emotional intelligence, because oriental medicine consider that the body and mental is an inseparable relation. The further study is necessary with the concept formulation and a historical investigation about an emotional intelligence. 목적: 이 연구의 목적은 정서지능의 한의학적 개념의 정립하고, 치료 방법을 개발하는 것이다. 도구: 우리는 정서지능과 관련된 문헌을 분석 및 조사하였다. 결과: 한의학에서 정서지능은 오행, 오지, 칠정의 이론에 부합한다고 볼 수 있다. 오지와 칠정은 오행상승과 오행상극의 이론에 따라 정서조절의 역할을 할 수 있기 때문에 정서조절 영역 IV에 부합한다고 볼 수 있다. 오지, 울증, 칠정조절은 정서의 안정과 정서조절에 적용시킬 수 있다. 결론: 이 연구는 한의학이 서양의학보다 정서지능에 관하여 더 많은 장점을 지니고 있다. 왜냐하면 한의학은 정신과 육체를 불가분의 관계로 보기 때문이다. 앞으로의 연구에서는 정서지능의 한의학적 개념의 정립과 문헌적 추가 연구가 필요할 것이다.

동결 해동한 포배 이식에 있어서 동결시기가 임신결과에 미치는 영향

김현정,김충현,이중엽,권재희,황도영,김기철,Kim, Hyun-Jung,Kim, Chung-Hyon,Lee, Joong-Yeup,Kwon, Jae-Hee,Hwang, Do-Yeong,Kim, Ki-Chul 대한생식의학회 2010 Clinical and Experimental Reproductive Medicine Vol.37 No.1

목 적: 배양 환경과 동결 기술이 발달함에 따라 동결 포배의 해동-이식의 빈도가 증가하고 있으며, 신선 주기와 마찬가지로 해동-이식 주기에서도 질 좋은 배아를 선별하는 것은 임신 성공 여부를 결정하는 아주 중요한 과제이다. 본 연구는 동결 당시 포배로의 발달 속도가 임신 결과에 미치는 영향을 알아보기 위하여, 수정 후 5일 및 6일째 동결한 포배의 해동-이식 후 임신율을 비교 분석하였다. 연구방법: 2006년 1월부터 12월까지 5일째 또는 6일째 동결한 포배를 해동하여 2007년 6월까지 융해 이식한 87명, 93주기를 대상으로 하였다. 동결법은 ethylene glycol과 DMSO를 이용한 유리화 동결법을 이용하였으며, 팽창 포배는 인위적인 수축을 시행 후 동결하였다. 해동 과정은 이식 전날 시행하여 15~18시간 배양액에서 배양 후 재팽창 여부를 확인하였다. 결 과: 5일째 동결한 포배를 해동-이식한 52주기와 6일째 동결한 포배를 해동-이식한 41주기에서 환자의 나이, 이식한 배아의 수, 해동 배아의 생존율 등 임신 결과에 영향을 미칠만한 요인들의 차이는 없었다. 그러나 생화학적 임신율, 임상적 임신율, 진행 임신율, 착상율 등은 5일째 동결한 포배를 해동-이식한 주기에서 높게 나타났다. 결 론: 5일째 동결한 포배를 해동-이식했을 때의 임신율은 6일째 동결한 포배를 해동-이식했을 때의 임신율보다 2배 이상 높았으며, 이는 신선 주기와 마찬가지로 해동-이식 주기에서도 동결 전 배아의 발달 속도의 차이를 임신 성공 예측의 중요한 지표로 사용할 수 있음을 시사한다. Objectives: Likewise fresh cycle, it is also important to select right blastocysts for transfer in purpose of improving the pregnancy and implantation rates in frozen-thawed embryo transfer (ET) cycles. To investigate the relationship between the developmental velocity at the time of cryopreservation and pregnancy rates, we compared pregnancy rates between the day 5 cryopreservation group and the day 6 cryopreservation group. Methods: Transfers of frozen-thawed blastocysts which had been cryopreserved by vitrification on day 5 or day 6 were performed between January 2006 and June 2007. Ethylene glycol, DMSO, and pull and cut straws were used for vitrification and artificial shrinkage was done in expanded blastocysts. Thawing was performed on the day before transfer and thawed blastocysts were cultured in for 15~18 hrs in Quinn's blastocyct media. Blastocyst survival was assessed before transfer and post-thaw survival was defined as >50% of cells remaining intact and blastocoele re-expansion by the time of transfer. Results: Transfers of thawed blastocyst had been cryopreserved on day 5 were 52 cycles and 41 transfer cycles were cryopreserved on day 6. Patient characteristics, the number of transferred embryos and the survival rate of thawed blastocysts were not different in each cryopreservation day. But the biochemical pregnancy, clinical pregnancy, ongoing pregnancy, and implantation rate were significantly high in transfer of frozen-thawed blastocyst which were cryopreserved on day 5. Conclusions: The clinical pregnancy and implantation rate of day-5 blastocyst showed significantly higher than those of day-6 blastocyst in frozen-ET cycles. This result indicated that developmental rate of blastocyst at cryopreservation time in frozen-thawed cycle is discriminative marker of pregnancy outcome as like in fresh cycle.

CFD기법을 연계한 자이로콥터의 전산구조동역학 해석

김현정,정세운,박효근,양창학,김동현,Kim Hyun-Jung,Jung Se-Un,Park Hyo-Keun,Yang Chang-Hak,Kim Dong-Hyun 한국전산구조공학회 2006 한국전산구조공학회논문집 Vol.19 No.3

본 논문은 자이로콥터의 유한요소 모델링과 로터의 회전에 의한 동하중을 고려한 전산진동해석을 수행하였다. 이를 위해 자이로콥터의 최종 조립된 3차원 CATIA 모델을 구축하였으며, 3차원 데이터를 바탕으로 비구조 질량을 포함한 구조진동해석을 위한 유한요소모델을 생성하였다. 실용적인 전산구조동역학 해석을 위해 상용 유한요소 해석프로그램인 MSC/NASTRAN과 자체 개발한 프로그램을 병용하여 사용하였다. 비행 중 회전하는 로터에 의해 발생하는 동하중은 상용 CFD 프로그램인 FLUENT를 이용하였다. 유체해석과 구조진동해석의 결합을 위해 자체적으로 통합 연계 시스템을 구축하였다. 3차원 구조의 효율적인 진동특성을 고찰하기 위해 모달영역에서 천이응답해석과 주파수응답해석을 수행하였다. 실제 자이로콥터의 연료조건과 비행조건을 고려하였으며, 전산해석을 통하여 고유진동, 주파수 응답 및 천이응답 특성을 고찰하였다. In this study, computational structural dynamic analyses of a gyrocopter have been conducted considering unsteady dynamic hub-loads due to rotating blades. 3D CATIA models with detailed mechanical parts we constructed and virtually assembled into the complete aircraft configuration. The dynamic loading generated by rotating blades in the forward flight condition are calculated by a commercial computational fluid dynamics (CFD) code such as FLUENT. Modal based transient and frequency response analyses are used to efficiently investigate vibration characteristics of the gyrocopter. Free vibration analysis results for different fuel and pilot conditions, frequency responses and transient responses for critical flight conditions are also presented in detail.

최명익 소설에 나타난 소통의 모색 양상

김현정(Kim Hyun-jung) 한국비평문학회 2008 批評文學 Vol.- No.28

The purpose of this paper is to question to compare his works before Korean Independence day, his works after, and to discover the internal logic of all of his works in these two periods. After Korean independence day the change in his realism was not illustrated but made by inner motive. He did not only reveal the korean unstable consciousness of koreans during the Japanese occupation when disturbance, frustration, and hopelessness were rampant, but he also showed intellectuals' disruption and ambiguity, criticism and communication methods at the time. The most remarkable point of his work is that he presented a communication method thatall wed hope get through the desperation which other writers couldn't. In this way he changed modernism to realism. In 「Pye-eo-in(폐어인)」 as the character Hyun-il(현일) passionately emphasized, "Although an Individual for himself is unfortunate it doesn't mean life looks dark or cursed due to that." He, the writer, tried to find the hope to break the colony in 1930s when people could no longer see a positive outcome. This made his novels reality, which isn't limited to the category of modernism before Korean Independence day. With this point, it is natural that he released his realism novels after Korean Independence day.

미디어 퍼포먼스 「마담 프리덤」에 나타난 주인공 여성의 재현과 그 의미

김주희(연구원,조교수) ( Ju-hee Kim ),김현정(연구원,조교수) ( Hyun Jung Kim ) 대한무용학회 2016 대한무용학회논문집 Vol.74 No.3

This paper explores meanings of a main female character in Madame Freedom (2013), a media performance of Hyo-jin Kim and Hyung-su Kim. This research investigates characteristics of the heroine in its original novel and movie; and examines what the roles of dances and media workings are respectively and what the choreographer utilizes the original works in Madame Freedom. This paper argues that the media work shows a Korean housewife``s passion, sexuality & freedom; ambivalent interpretations; and strategic reconstruction of particularity and universality. These provide a way to produce diverse interpretations by exploring complex relations of novel, movie, and media performance.

소아 세균성 수막염에서 원인균에 관한 고찰(1992-2002)

김현정,이지원,이경일,이형신,홍자현,한승훈,황경태,Kim, Hyun-Jung,Lee, JI-Won,Lee, Kyung-Yil,Lee, Hyung-Shin,Hong, Ja-Hyun,Hahn, Seung-Hoon,Whang, Kyung-Tai 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.11

목 적 : 국내 소아 세균성 수막염의 원인 균주가 시대적으로 차이가 있는지 알아보고자 하였다. 방 법 : 1992년 1월부터 2002년 12월까지 가톨릭대학교 대전성모병원에 세균성 수막염으로 입원한 40례(신생아군 14례, 소아군 26례)를 대상으로 하여 신생아군은 1970-80년대의 국내 보고와 비교하였고, 소아군은 Hib 백신이 도입되기 전후 시기의 H. influenzae 수막염의 발생 빈도를 비교하였다. 결 과 : 신생아군에서 GBS(33.3%)가 가장 흔한 원인 균주였으며 국내에서도 그람 음성균에서 GBS를 주로 하는 그람 양성 균주로의 변화 양상을 보였다. 소아군에서는 Hib 백신이 도입되기 이전인 1992년-1995년 사이에는 11례의 세균성 수막염 중 6례(55%)가 H. influenzae에 의한 수막염이었다. Hib 백신이 일반화된 시기인 1999-2002년에 7명의 세균성 수막염 환아 중 2명(29%)으로 H. influenzae 수막염이 감소하는 추세를 보였지만 통계학적으로 유의하지는 않았다(P=0.36). 결 론 : 신생아 수막염에서 GBS가 주된 원인 균주로 나타났으며, 이후 연령에서는 Hib 백신이 도입된 이후 H. influenzae에 의한 수막염은 감소하는 경향을 보였다. Purpose : This study was performed to assess the difference of organisms causing bacterial meningitis according to time. Methods : We analyzed retrospectively 40 medical records of bacteriologically proven meningitis from 1992 to 2002. We divided them into two groups; neonate's group(14 cases), and children's group(26 cases). The results of the neonate's group were compared with those of previously reported articles in Korea, in 1970s-1980s. The causative agents of the children's group were analyzed according to the stage before and after the introduction of H. influenza type b(Hib) vaccine. Results : In neonates, Group B streptococci(GBS) was the most common cause of bacterial meningitis. There was a trend in Korea that major causative agents of neonatal bacterial meningitis have changed from gram negative bacteria including E. coli to gram positive bacteria including GBS. In children, H. influenzae was isolated in six out of 11 cases(55%) in 1992-95, before the introduction of Hib vaccine, while two out of seven(29%) were isolated in 1999-2002, after the introduction of the Hib vaccine. Conclusion : Our study showed that the most common agent of neonatal bacterial meningitis was GBS. There was a trend that after the introduction of Hib vaccine, the incidence of H. influenza meningitis decreased in children.

암종으로 오인된 전이 폐포횡문근육종의 세침흡인 세포소견 -1예 보고-

김현정,임성직,박경미,Kim, Hyun-Jung,Lim, Sung-Jik,Park, Kyeong-Mee 대한세포병리학회 2005 대한세포병리학회지 Vol.16 No.1

Fine-needle aspiration cytology (FNAC) has been used extensively in the diagnosis of metastatic malignancies. However, metastatic soft tissue sarcomas are often overlooked, primarily due to the low frequency with/ which they occur. Here, we report a rare case of metastatic rhabdomyosarcoma in both cervical lymph nodes, which was detected by FNAC. A 45-year-old woman presented with anosmia, postnasal drip, and sneezing, symptoms which had persisted for 1 month. The patient was found to have a tumorous lesion at the upper portion of the mid-turbinate, with multiple enlarged cervical lymph nodes, and this lesion was examined closely at our facility. FNA cytology smears obtained from both cervical lymph nodes revealed a high degree of cellularity, and displayed cohesive clusters with gland-like spaces, as well as single isolated cells with abundant karyorrhectic debris. The tumor cells exhibited round to oval nuclei containing fine chromatin, occasional small nucleoli, and scanty cytoplasm, or a total lack of cytoplasm. Some of the tumor cells were arranged in multinucleated forms and abundant dense eosinophilic cytoplasms, reminiscent of a rhabdomyoblast. The histological findings on the lymph nodes revealed an outstanding sinusoidal infiltration and a prominent alveolar growth pattern, interspersed with occasional typical rhabdomyoblasts. The immunohistochemical results [desmin (+), myoglobin (+), myogenin (+), pan CK (-), synaptophysin (-), neuron specific enolase (-)] supported a confirmative diagnosis of alveolar rhabdomyosarcoma. Alveolar rhabdomyosarcoma is a representative sarcoma, which typically manifests with nodal metastasis and carcinoma-like clustering. The cytopathologist should remain alert upon encountering unusual morphology, so that the possibility of this condition, although somewhat remote, should not be dismissed or overlooked.