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- 저자 : 김해유 ( Hae Yu Kim ) (검색결과 5 건)
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김정수 ( Jung Soo Kim ),전경동 ( Kyoung Dong Jeon ),김해유 ( Hae Yu Kim ),이선일 ( Sun Il Lee ) 대한뇌종양학회 대한신경종양학회 2014 Brain Tumor Research and Treatment Vol.2 No.1
PMalignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma of ectomesenchymal origin. We experienced a case of metastatic MPNST from oral cavity onto skull with aggravation of malignant phenotype, and reported it with literature review. A 75-year-old woman was presented with a 3-months history of growing and indurate mass on her frontal skull. The patient underwent bifrontal craniectomy with safety margin from the lesion. Two years before, she had undergone trans-oral wide resection and anterior partial maxillectomy to extirpate the MPNST at oral cavity. No adjuvant therapy was added at that time. Histopathologic examination showed an poorly differentiated sarcoma. The tumor demonstrated palisade alignment, necrosis, cellular pleomorphism and increased mitosis of tumor cells. And their immunohistochemical studies showed positive in S-100, CK, CD68, Vimentin, Actin, and CD99. She received postoperative adjuvant radiation therapy. It was obvious that the tumor had changed toward more malignant phenotype. We strongly recommend a careful follow-up of remote area even after the wide resection in MPNST patient.
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김정수 ( Jung Soo Kim ),전경동 ( Kyoung Dong Jeon ),김해유 ( Hae Yu Kim ),이선일 ( Sun Il Lee ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2012 대한뇌종양학회지 Vol.11 No.2
PMalignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma of ectomesenchymal origin. We experienced a case of metastatic MPNST from oral cavity onto skull with aggravation of malignant phenotype, and reported it with literature review. A 75-year-old woman was presented with a 3-months history of growing and indurate mass on her frontal skull. The patient underwent bifrontal craniectomy with safety margin from the lesion. Two years before, she had undergone trans-oral wide resection and anterior partial maxillectomy to extirpate the MPNST at oral cavity. No adjuvant therapy was added at that time. Histopathologic examination showed an poorly differentiated sarcoma. The tumor demonstrated palisade alignment, necrosis, cellular pleomorphism and increased mitosis of tumor cells. And their immunohistochemical studies showed positive in S-100, CK, CD68, Vimentin, Actin, and CD99. She received postoperative adjuvant radiation therapy. It was obvious that the tumor had changed toward more malignant phenotype. We strongly recommend a careful follow-up of remote area even after the wide resection in MPNST patient.
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이수환 ( Su Whan Lee ),김해유 ( Hae Yu Kim ),이선일 ( Sun Il Lee ) 대한뇌종양학회·대한신경종양학회·대한소아뇌종양학회 2011 대한뇌종양학회지 Vol.10 No.1
Introduction:Multicentric glioblastoma is rare disease entity, which is frequently mimicking metastatic brain tumor. We experienced a case of multicentric glioblastoma which was diagnosed finally after multiple craniotomies for the multicentric intracranial lesions having been believed as metastatic brain tumor. We reported this rare case with literature reviews. Case Report:A 48-year-old man had underwent Novalis radiosurgery for multiple malignant tumors in other institute. He had no other malignant lesion in other part of body. He was followed up for 10 months and was taken brain magnetic resonance image (MRI) which showed progressed and newly developed intracranial lesions. He visited our institute with the images for Gamma Knife radiosurgery. During follow up after second radiosurgery, he developed neurological symptoms due to increasing intracranial lesions. We performed multiple craniotomies for large two lesions. He gradually recovered after surgery. Pathological report was glioblastoma. He underwent chemotherapy without radiotherapy due to previous radiosurgeries. Conclusion:This case`s intracranial lesions were considered as metastatic brain tumor undiagnosed primary tumor due to the multicentricity and formation of new lesions for several months. However this was not based on pathological diagnosis which should be necessary to decide precise treatment. This rare case might give us an education about the importance of consideration of invasive procedures for pathological diagnosis in the case of multiple intracranial lesions without evidence of extracranial lesions.
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내시경적 비강접근 농양배액술로 치료한 Pott’s puffy tumor 1례
양승현(Seung-Hyeon Yang),김용완(Yong Wan Kim),김해유(Hae Yu Kim) 대한두개저학회 2019 대한두개저학회지 Vol.14 No.1
Pott’s puffy tumor is soft tissue swelling of the forehead due to subperiosteal edema and the accumulation of pus or granulation tissue. It is usually associated with osteomyelitis of the frontal bone secondary to frontal sinusitis. An 11-year-old boy was admitted with left periorbital swelling and pain that had become aggravated from 3 days prior. Orbital computed tomography revealed pansinusitis with osteomyelitis on the left orbital roof. He underwent magnetic resonance image that showed an extradural abscess approximately 1.9 x 1.5 cm in his anterior cranial fossa. His serum test revealed increased white blood cell counts and an elevated C-reactive protein level. We performed a middle meatal antrostomy and frontal sinusotomy via a transnasal endoscope. Coagulase-negative Staphylococcus was cultured from the pus within his frontal sinus. Antibiotic therapy was administered for 6 weeks. The patient’s epidural abscess and pansinusitis subsided completely. We report herein a rare case of Pott’s puffy tumor patient who was treated with a transnasal endoscopic sinusotomy and antibiotic therapy.
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