박판보 요소와 셸 요소를 이용한 T 조인트 진동 해석

김진홍,김현석,김윤영,Kim, Jin-Hong,Kim, Hyeon-Seok,Kim, Yun-Yeong 대한기계학회 2000 大韓機械學會論文集A Vol.24 No.9

This paper proposes an efficient beam-shell modeling technique for the free vibration analysis of a T-joint thin-walled beam structure. Except a small portion of a T-joint which is modeled by shell elements, the structure is modeled by thin-walled beam elements that can describe warping and distortion. In order to match the shell and thin-walled beam elements at the interface of the dissimilar elements, a technique based on a pseudo inverse matrix is formulated. This paper also examines the role of the thin-walled element taking into account the distortion and warping deformation degrees of freedom in predicting accurately the dynamic characteristics of a T-joint thin-walled structure.

물관리기본법(안)의 쟁점 사항

김진홍,Kim, Jin-Hong 한국수자원학회 2008 물과 미래(한국수자원학회지) Vol.41 No.3

Sarcoma Immunotherapy: Confronting Present Hurdles and Unveiling Upcoming Opportunities

김진홍,김이준,Hyun Guy Kang,정세한,Sharmin Afroz,Donghyun Kang,Jeonghwan Noh,서주연,June Hyuk Kim,유혜진 한국분자세포생물학회 2023 Molecules and cells Vol.46 No.10

Sarcomas are rare and heterogeneous mesenchymal neoplasms originating from the bone or soft tissues, which pose significant treatment challenges. The current standard treatment for sarcomas consists of surgical resection, often combined with chemo- and radiotherapy; however, local recurrence and metastasis remain significant concerns. Although immunotherapy has demonstrated promise in improving long-term survival rates for certain cancers, sarcomas are generally considered to be relatively less immunogenic than other tumors, presenting substantial challenges for effective immunotherapy. In this review, we examine the possible opportunities for sarcoma immunotherapy, noting cancer testis antigens expressed in sarcomas. We then cover the current status of immunotherapies in sarcomas, including progress in cancer vaccines, immune checkpoint inhibitors, and adoptive cellular therapy and their potential in combating these tumors. Furthermore, we discuss the limitations of immunotherapies in sarcomas, including a low tumor mutation burden and immunosuppressive tumor microenvironment, and explore potential strategies to tackle the immunosuppressive barriers in therapeutic interventions, shedding light on the development of effective and personalized treatments for sarcomas. Overall, this review provides a comprehensive overview of the current status and potential of immunotherapies in sarcoma treatment, highlighting the challenges and opportunities for developing effective therapies to improve the outcomes of patients with these rare malignancies.

회원작품 - 대율리주택 _ 심온재(心穩齋)

김진홍,Kim, Jinhong 대한건축사협회 2018 建築士 Vol.585 No.-

생태환경 기술에서 수공학의 역할

김진홍,Kim Jin-Hong 한국수자원학회 2006 물과 미래(한국수자원학회지) Vol.39 No.4

환경친화적인 하천복원 사업의 기술개발 방안

김진홍,Kim, Jin-Hong 한국관개배수위원회 2007 한국관개배수논문집 Vol.14 No.2

Chord 시스템에서 이동장비의 이동성 지원 방안 연구

김진홍,조인준,Kim Jin-Hong,Jo, In-June 배재대학교 공학연구소 2006 공학논문집 Vol.8 No.1

분산해쉬테이블 기반의 구조적 P2P 시스템의 대표적인 예로 Chord 시스템은 이동성에 대한 고려가 없다. 이로 인해 이동 노드가 이동하여 새로운 IP를 갖게 된다면 이동 노드뿐만 아니라 네트워크 자체에도 성능 저하를 유발할 수 있다. Chord 뿐만 아니라 대부분의 P2P 시스템 모델에서 이동 노드의 이동성에 대한 고려 없이 고정 노드만으로 구성되는 시스템으로 연구되어 왔고 최근 들어 P2P 시스템에서 이동성에 대한 연구가 이루어지고 있는 실정이다. 본 논문에서는 구조적 P2P 시스템의 하나인 Chord 시스템에서 이동성을 지원하기 위한 방안을 제안한다. 이동 노드는 네트워크에 이미 존재하는 고정 노드를 부모 노드로 하여 네트워크에 참여하고, 부모 노드를 통해 서비스를 요구 혹은 제공하도록 한다. Chord system, structured P2P system based on distributed hashed table, didn't consider the mobility of mobile device. Mobility of mobile node may cause performance falloff of both mobile node and P2P network. Not only Chord system but also the greater part of P2P system didn't consider the mobility of mobile node. Recently it is researched on mobility in P2P system. In this paper, it proposed the method of the supporting mobility in chord system. Mobile node joins to the P2P network through the stationary node meaning the parents node. Mobile node require or offer the service for the parents node.

테트라싸이클린 함유 Slow release system이 진행된 치주질환에 미치는 효과에 대한 임상 및 암시야현미경적 연구

김진홍,조규성,채중규,김종관,Kim, Jin-Hong,Cho, Kyoo-Sung,Chai, Jung-Kui,Kirn, Chong-Kwan 대한치주과학회 1990 Journal of Periodontal & Implant Science Vol.20 No.1

식생에 의한 하안 퇴적과 침식 경감

김진홍,Kim, Jin-Hong 응용생태공학회 2015 Ecology and resilient infrastructure Vol.2 No.2

본 연구에서는 현지조사를 통해 식생의 하안 퇴적과 침식 경감을 판단하였다. 달뿌리풀은 임계유속 1.0 m/s-1.2 m/s을 기준으로 0.2 m 정도의 하안 퇴적과 0.3 m-0.4 m의 침식 경감 기능을 발휘하였다. 갈대는 임계유속 0.6 m/s-0.7 m/s을 기준으로 0.1 m-0.4 m의 하안 퇴적과 0.2 m-0.3 m의 침식 경감 기능을 발휘하였다. 갯버들은 임계유속 1.2 m/s-1.4 m/s을 기준으로 0.1 m-0.2 m의 하안 퇴적과 0.4 m-0.5 m의 침식 경감 기능을 발휘하였다. 물억새는 임계유속 0.6 m/s-0.7 m/s을 기준으로 0.1 m-0.4 m의 하안 퇴적과 0.1 m-0.2 m의 침식 경감 기능을 나타내었다. 조사 대상 식생 중 갯버들이 가장 높은 하안 침식 경감 기능을, 물억새가 가장 낮은 침식 경감 기능을 발휘하였다. 그러나 현지조사 결과 대상 식물종 모두 하안 퇴적 및 침식 경감 기능을 발휘함으로써 안정하도 형성에 기여함을 알 수 있었다. This paper presents the field investigation of deposition and erosion relief of a riverfront using vegetation. The results obtained were as follows: Phragmites japonica showed 0.2 m of deposition and 0.3 m-0.4 m of erosion relief of river front by the critical velocity of 1.0 m/s-1.2 m/s. P. communis showed 0.1 m-0.4 m of deposition and 0.2 m-0.3 m of erosion relief by the critical velocity of 0.6 m/s-0.7 m/s. Salix gracilistyla showed 0.1 m-0.2 m of deposition and 0.4 m-0.5 m of erosion relief by the critical velocity of 1.2 m/s-1.4 m/s. Miscanthus sacchariflorus showed 0.1 m-0.4 m of deposition and 0.1 m-0.2 m of erosion relief by the critical velocity of 0.6 m/s-0.7 m/s. S. gracilistyla had the greatest role, while M. sacchariflorus had the lowest role for erosion relief. These results showed that aquatic plants had an effective role in sustaining a stable channel.

정자의 여러가지 형태학적 특징에 따른 정자 침투능의 평가

김진홍,정기욱,유영옥,권동진,임용택,김장흡,나덕진,이진우,Kim, J.H.,Jung, K.W.,Lew, Y.O.,Kwon, D.J.,Lim, Y.T.,Kim, J.H.,Nha, D.J.,Lee, J.W. 대한생식의학회 1994 Clinical and Experimental Reproductive Medicine Vol.21 No.1

Morphological estimation of human spermatozoa is complicated by the fact that there is great natural variation in shape. This natural variation in shapes makes it difficult to say which forms are associated with infertility and which are normal variations. Possibly post coital test or in vitro cervical mucus penetration tests will help to clarify this question by showing which sperm are capable of penetration. The purpose of this investigation was performed to assess distribution of various morphological abnormalities according to the ability of sperm to penetrate cervical mucus. The sperm-mucus penetration using hen's egg white as substituting mucus for human cervical mucus was done in 45 fertile men with normal semen analysis and 122 infertile men with abnormal seminal parameters more than one. The female partners of 122 infertile couples showed normal results in the female fundamental test for fertility. Conventional semen analysis was evaluated according to the WHO standard normal(l980). The detailed classification of the abnormal sperm was made according to David et al(l975). The vitality of the sperm samples determined by eosin yellow-nigrosin stainig according to the method of Eliasson(l977). Results were as follw; 1. The patients had significantly lower total sperm count, motility (%), normal morphology (%), viability and total functional sperm fractions(TFSF) than fertile donors. 2. The mean value of sperm penetration distance of the patients(28.69${\pm}$11.02mm) showed significantly lower than fertile donors(37.33${\pm}$5.49mm). And 43/45 fertile donors(95.5%) as well as 57/122 patients(46.7%) had over 30mm in sperm penetration distance respectively. While 2/45 fertile donors(4.5 %) and 65/122 patient(53.3%) had under 30mm in sperm penetration distance respectively. 3. The morphological abnormalities in fertile donors were significantly lower 23.04${\pm}$5.83% (head = 12.89${\pm}$4.98, neck=6.11${\pm}$3.83%, and tail=3.43${\pm}$2.65%), compared to 36.03${\pm}$14. 40% in patients(head = 15.98 8.60%, neck 11.20${\pm}$6.56% and tail=8.70${\pm}$6.55%). Also, 3 types of sperm abnormalities including head, neck and tail were significantly lower in patient than fertile donors, respectively. Both the patients and fertile donors showed higher distribution of sperm with abnormal head than abnormal neck and tail. 4. The mean morphological abnormalities(SP>30mm) of the patients(30.68 11.64%; head = 15.95${\pm}$9.35%, neck=8.14${\pm}$4.21 %, tail=6.56${\pm}$5.64%) were significantly lower compared to patients(40.72${\pm}$15.01 %; head=16.02${\pm}$7.69%, neck 13.89${\pm}$7.82%, tail=1O.58${\pm}$6.75%) under 30mm in sperm penetration distance. Also, both groups over 30mm and under 30mm in sperm penetration showed distance higher distribution of sperm with abnormal head than abnormal neck and tail. The morphological abnormalities of head did not show significant difference but abnormal neck and tail were significant difference between the over 30mm and under 30mm group in sperm penetration distance.