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김정훈,최재영,최영식<SUP>1<,SUP>,정미희<SUP>2<,SUP>,정경순<SUP>2<,SUP>,Jung Hoon Kim,M,D,Jae Young Choi,M,D,Young Sik Choi,M,D,<SUP>1<,SUP>,Mi Hee Jung,M,D,<SUP>2<,SUP> and Kyung Soon Jung,M,D,<SUP>2<,SUP> 대한갑상선-내분비외과학회 2011 The Koreran journal of Endocrine Surgery Vol.11 No.1
Purpose: Ultrasound (US) elastography is a newly developed imaging technique for assessing tissue stiffness by measuring the degree of the tissue's deformation in response to the application of an external force. This technique has recently been applied for making the diagnosis of nodular thyroid disease. The purpose of this study was to evaluate the diagnostic utility of US elastography for differentiating benign thyroid nodules from malignant thyroid nodules. Methods: A total of 63 consecutive patients with thyroid nodules and who were referred for surgical treatment were examined in this study. Seventy-five nodules in these patients were examined by US B-mode, color Doppler US and US elastography. The final diagnosis was obtained from the histologic findings. The tissue stiffness on ultrasound elastography was scored from 1 (elasticity in the whole nodule) to 5 (no elasticity in the nodule and in the posterior shadowing). Results: On US elastography, 18 of 32 benign nodules (56.3%) had a score of 1 to 3, whereas 23 of 43 malignant nodules (62.8%) had a score of 4 to 5. With applying a US elastography score of 4-5 as an indicator for malignancy, the sensitivity, specificity, positive predictive value and negative predictive value of US elastography were 65.9%, 52.9%, 62.8% and 56.3%, respectively. Of the 14 follicular tumors, 12 were follicular adenoma and four were follicular carcinoma. The sensitivity and specificity of US elastography for diagnosing follicular carcinoma were 50.0% and 81% (56=69), respectively. The positive and negative predictive values were 55.2% (16=29) and 60.0%, respectively. The accuracy of the technique was 57.1%. The findings of US elastography were not significantly correlated with the histopathologic findings. Conclusion: This study has shown that US elastography may be not useful for differentiating between benign and malignant thyroid nodules. Further studies are needed to confirm the usefulness of US elastography for making the differential diagnosis of thyroid nodules. (Korean J Endocrine Surg 2011;11:12-17)
유료 콘텐츠의 N-스크린 서비스를 위한 일시적 시청권한 위임 기법
김정훈,이훈정,김상진,오희국,Kim, Jung-Hoon,Lee, Hoon-Jung,Kim, Sang-Jin,Oh, Hee-Kuck 한국정보처리학회 2011 정보처리학회논문지 C : 정보통신,정보보안 Vol.18 No.3
최근, 통신기술의 급속한 발전으로 인해 때와 장소에 구애받지 않고 콘텐츠를 소비하고자 하는 사용자의 욕구와 새로운 비즈니스 모델을 찾고자 하는 사업자의 바람이 맞물려 N-스크린 서비스 전략이 주목 받고 있다. N-스크린은 TV, 컴퓨터, 휴대용 단말 등 다양한 기기에서 끊김 없이 콘텐츠를 공유, 소비할 수 있도록 지원하는 스크린 확장 개념의 서비스로서 미국의 통신회사인 AT&T에서 처음 제안했던 3-스크린 서비스 전략이 발전된 형태이다. 유료 콘텐츠에 대한 N-스크린 서비스에서 유료 콘텐츠에 대한 끊김없는 스크린 전환을 지원하기 위해서는 스크린을 전환하고자 하는 기기로 일시적인 시청권한을 부여해야 한다. 하지만 접근제어 시스템을 사용하고 있는 현재의 방송환경에서는 일시적으로 권한을 부여하는 것이 불가능하다. 본 논문에서는 현재 방송환경에서 유료콘텐츠에 사용하고 있는 접근제어 기법에 대해 살펴보고 일시적인 권한 부여를 할 수 없는 이유에 대해서 살펴본 뒤 현재 사용 중인 접근제어 기법을 기반으로 추가적인 키를 사용해 시청권한 문제를 해결하는 방법을 제안한다. Recently, the strategy for N-screen service is in the spotlight along with the consumer's need to use contents regardless of time and place due to the rapid development of communication technology, which is meshing with the desire of service providers seeking a new business model. N-screen, as a screen-extension-concept service which enables consumers to continuously share and use contents in various equipments such as TV, computer and portable terminals, is an advanced type of 3-screen service strategy initially proposed by AT&T, an American telecommunication company. In the N-screen service for pay-contents, in order to support continuous screen changes to and from various equipments, temporary watching right should be given to the equipment intended for screen change. However, it is impossible to give the temporary watching right in the present broadcasting environment, adopting an access-control system. In this paper, the access-control technology being used for pay-contents in the present broadcasting environment and the reason for not being able to give temporary watching right, will be examined. After the examination, the solution for delegation of watching right by using an additional key on the basis of currently used access-control technology, will be proposed.
Recurrence and Extraneural Metastasis in 31 Meningeal Hemangiopericytomas
김정훈,김준수,김창진,황승균,정희원,권병덕,Kim, Jeong Hoon,Kim, Joon Soo,Kim, Chang Jin,Hwang, Sung Kyun,Jung, Hee Won,Kwun, Byung Duk The Korean Neurosurgical Society 2001 Journal of Korean neurosurgical society Vol.30 No.3
목 적 : 높은 재발율과 전이 가능성의 특징을 갖고 있는 수막 혈관외세포종은 perivascular pericytes에서 기원하는 드문 종양으로, 저자들이 경험한 수막 혈관외세포종에 있어서 종양의 재발 및 신경계외 전이에 대하여 알아 보고자 한다. 연구 대상 및 방법 : 1982년부터 1999년까지 수술을 시행하여 수막 혈관외세포종으로 진단받은 31명의 환자를 대상으로 후향적 연구를 시행하였다. 진단 후 재발까지의 기간, 재발에 영향을 미칠 수 있는 여러 가지 인자들, 그리고 신경계외 전이의 기간 및 부위 등을 분석하였다. 결 과 : 총 31명의 환자들 중 12명의 환자들에서 원발성 부위에 종양이 재발하였다(38.7%). 전체의 환자들에서 재발이 발생하지 않았던 평균 기간(recurrence-free period : RFP)은 104개월이었으며 처음 수술 후 5년, 그리고 10년의 재발이 발생하지 않았던 율(recurrence free period : RFP)은 각각 59.2%, 33.6% 이었다. 원발성 부위에 종양의 재발을 보였던 12명의 환자들 중 4명의 환자들에서 첫 수술 후 5년 이후에 재발을 관찰 할 수 있었다. 처음 수술시의 절제 정도가 재발에 가장 큰 영향을 미쳤다. 처음 수술시에 완전 절제한 군의 RFP는 111 개월이었으며, 추적 관찰 5년째 RFR는 완전 절제한 경우 72.7%, 불완전 절제한 경우 20.8%로 그 차이는 통계 적으로 유의하였다(p=0.0060). 통계적으로 유의성은 없었지만 완전 절제 후 부가적인 방사선 치료를 시행하였을 경우가 완전 절제만을 시행한 경우보다 RFR가 높아 추적 관찰 5년째의 RFR는 각각 100%, 그리고 70.3% 이었다(p=0.3359). 4명의 환자들(12.9%)에서 수막 혈관외세포종의 신경계외 전이가 발생하였으며, 이 경우 신경계 외 전이의 평균 기간은 107개월, 그리고 추적 관찰 5년, 10년째의 신경계외 전이율은 각각 4.4%, 24.9% 이었다. 결 론 : 수막 혈관외세포종은 수술적 제거 후 원발성 부위에 또는 원발성 부위에서 멀리 떨어진 부위에 재발의 가능성이 무척 높은 종양이다. 이러한 재발의 가능성을 줄이는 가장 중요한 인자는 수술적 제거 정도로 처음 수술시에 가능한 완전 절제를 시도하여야 한다. 그리고 처음 수술시에 완전 절제가 가능하였다고 하여도 완전 절제 후 부가적인 방사선 치료를 시행하는 것이 재발의 위험성을 낮출 수 있을 것으로 생각한다. 원발성 부위의 재발 또는 신경계외 전이는 오랜 시간이 지난 후에도 가능할 수 있으므로 장기간의 추적 관찰이 필요하다고 생각한다. Purpose : Meningeal hemangiopericytoma(M-HPC), characterized by a high local recurrency and metastatic potential, is a rare neoplasm arising from perivascular pericytes. A retrospective study was performed to identify the recurrence and extraneural metastasis in M-HPC. Materials and Methods : We reviewed the records of 31 M-HPC patients treated from 1982 through 1999 at our institution. The time to recurrence and the various parameters affecting recurrence were determined. Extreneural metastasis was also analyzed. Results : The rate of local recurrency was 38.7%(12/31). The overall average recurrence-free period(RFP) before the first recurrence was 104 months, with overall recurrence-free rates(RFRs) at 5 and 10 years after first surgery of 59.2% and 33.6%, respectively. Of the 12 patients who experienced local recurrence, 4 had recurrences 5 years later after the first surgery. Complete excision at the first operation significantly extended the average time before first recurrence from 43 to 111 months. The 5-year RFRs for the groups of complete excision and incomplete excision were 72.7% and 20.8%, respectively(p=0.0060). Although there was no statistical significance, complete excision followed by adjuvant radiotherapy of more than 50Gy extended the RFP. The 5-year RFRs for the groups of complete excision and complete excision with adjuvant radiotherapy were 70.3% and 100%, respectively(p=0.3359). Four patients(12.9%) presented one or more extraneural metastases that were developed at an average of 107 months after the first operation with the 5- and 10-year metastasis rates of 4.4% and 24.9%, respectively. Conclusions : M-HPC has a propensity to recur either locally or at distant sites after surgical resection. Complete excision is the most important factor to reduce recurrence. However, even with complete excision, adjuvant radiotherapy of more than 50Gy significantly reduces the risk of recurrence. Local and distant recurrences may occur after a prolonged disease-free interval, emphasizing the need for long-term follow-up.
보중익기탕(補中益氣湯)이 생쥐의 기아(飢餓)stress에 미치는 영향
김정훈,이태희,Kim, Jung-Hoon,Lee, Tae-Hee 대한한의학방제학회 2006 大韓韓醫學方劑學會誌 Vol.14 No.1
Objectives: We investigated the effect of Bojungikgitang on the change of the corticosterone and the rectal temperature of the mice induced by starvation stress. Methods: After administration of Bojungikgitang three times, mice were starved. The corticosterone and rectal temperature were measured after 36.5 hours starvation stress. Results : The plasma corticosterone level in Bojungikgitang(0.25g/Kg) was decreased comparing with the Control group and the rectal temperature in the Bojungikgitang(1.0g/Kg) was increased comparing with the Control group. Conclusion : it might be recognized that Bojungikgitang has anti starvation stress effect, and also it might be needed further study in various viewpoints.
지하시설물 유지관리 업무프로세스 개선 방향에 관한 연구 ; 지역난방 시설을 중심으로
김정훈,임시영,Kim, Jung-Hoon,Lim, Si-Yeong 한국공간정보학회 2009 한국공간정보학회지 Vol.17 No.3
The growth of sensor and wireless communication technology enable us to monitor the status of things in real-time. There are many attempts to apply the real-time monitoring in various fields. Especially, the real-time monitoring in facility management fields has attracted much attentions recently. But it is difficult to apply recent technologies including sensor, wireless communication and Geospatial information technologies, etc, to the real situation directly. One of the reasons is that facility managers who are familiar with existing processes may resist the change induced by new technologies. So it is necessary to close the gap between new technologies and existing processes by improving the existing processes prior to putting them in the field. In this paper, we suggest the management process improvement focused on the district heating facilities. 센서 및 무선통신 기술의 발달로 인해 사물의 상태에 대한 실시간 모니터링이 가능해지고 있다. 이에 다양한 분야에서 실시간 모니터링을 활용하고자 하는 시도가 진행되고 있으며, 특히 시설물 관리 분야에서도 이를 활용하여 시설물 관리의 지능화를 추진하고 있다. 그러나 센서 기술, 통신 기술, 공간정보 등 핵심 요소기술을 바로 현장에 적용하기에는 다소 무리가 있다. 현장에서는 새로운 기술이 적용되기 이전의 업무프로세스를 통해 시설물 관리가 이루어지고 있기 때문이다. 즉, 새로운 기술을 현장에 적용하기 위해서는 필연적으로 업무프로세스의 개선을 병행하여 기술과 현장의 간극을 최소화함으로써 기술의 현장 적응력을 높일 필요성이 존재한다. 이에 본 연구에서는 기존의 지하시설물 유지관리 프로세스를 살펴보고, 실시간 모니터링이 가능하다는 가정 하에 지하시설물 유지관리 업무프로세스의 개선 방향을 제시하고자 한다. 본 연구에서는 지역난방 업무프로세스를 대상으로 하였다.
체외수정시술시 예후 인자로서 정자 첨체반응 유발검사의 유용성
김정훈,채희동,강은희,추형식,전용필,강병문,장윤석,목정은,Kim, Chung-Hoon,Chae, Hee-Dong,Kang, Eun-Hee,Chu, Hyung-Sik,Cheon, Yong-Pil,Kang, Byung-Moon,Chang, Yoon-Seok,Mok, Jung-Eun 대한생식의학회 1998 Clinical and Experimental Reproductive Medicine Vol.25 No.3
It is well known that the clinical test for responsibility of accurate fertilization capacity in male partners is very important to diagnose and treat the infertility. However, it has been reported that the traditional semen analysis cannot accurately predict fertilization and pregnancy potential. The present study was performed to evaluate the acrosomal reaction to ionophore challenge (ARIC) test as a prognostic indicator for fertilization of sperm and oocyte in an in vitro fertilization and embryo transfer (IVF-ET) program. From March 1996 to Februry 1997, 30 couples undergoing IVF program were allocated to this study group. All female partners in the study group were 35 years old or less and their serum level of basal follicle stimulating hormone (FSH) and estradiol $(E_2)$ were normal. All the male partners have normal parameters of semen analysis. The ARIC tests were performed on the day of ovum pick up and in vitro insemination in all the male partners. The controlled ovarian hyperstimulation (COH) using luteal long protocol of gonadotropin releasing hormone (GnRH) agonist was used in all couples for IVF-ET. The acrosomal reaction with $10{\mu}l$ of 10% DMSO was induced spontaneously in $10.1{\pm}9.8%$, and acrosomal reaction with calcium ionophore A 23187 was induced in $27.4{\pm}18.1%$, and the ARIC value was $17.4{\pm}16.2%$. There were no significant correlation between the ARIC value and the fertilization rate ($r^2$=0.044, p=0.268). There were also no significant correlation between the ARIC value and the percentage of the grade I, II embryos ($r^2$=0.046, p=0.261). On the basis of above results, it was suggested that ARIC test might not be a useful prognostic indicator for fertilization in IVF-ET in male partners with normal parameters of conventional semen analysis. We guessed that IVF-ET could be performed to the patients primarily without universal appilcation of ARIC test to all male partenrs, and if fertilization failure occurs, the micro assisted fertilization (MAF) such as intracytoplsmic sperm injection (ICSI) might be used as an alternative mode of treatment with acceptable success rate.
지능형 지하시설물관리를 위한 상수도 모니터링 기술개발의 우선순위 평가에 관한 연구
김정훈,이미숙,한재일,Kim, Jung-Hoon,Yi, Mi-Sook,Han, Jay-Il 한국공간정보학회 2008 한국공간정보학회지 Vol.16 No.2
최근 지방자치단체들은 u-City 사업구상을 통해 지능형 지하시설물 관리를 계획하고 있지만, 지하시설물의 지능화를 위해서는 막대한 재원이 소요되므로 단계적 접근이 필요하다. 따라서 본 연구의 목표는 센싱기술 개발의 우선순위가 높은 상수도 모니터링 항목을 도출하여 기술적 실현가능성과 경제적 파급효과가 높은 킬러어플리케이션을 발굴하는데 있다. 이를 위해 상수도 업무분석, 심층면담조사, 지자체 설문조사, 전문가의견조사 등을 통해 최종 모니터링 항목을 도출하였다. 분석 결과 유량계 유량, 상수관로 누수 균열, 상수관로 압력, 정수장 유량에 대한 모니터링 기술개발의 우선순위가 높게 나타났다. 이러한 연구결과는 상수도 시설물 관리의 실제적인 수요와 우선순위를 도출하고 평가하였다는데 의의가 있으며, 향후 지하시설물 지능화 관련 기술개발의 방향성 제시에 기여할 것이라 기대된다. Nowaday, local governments have planned to manage intelligent underground facilities through the u-City project. But, the intelligent underground facilities are in need of the progressive approach because of the required huge financial resources. Therefore, the objectives of this research are (1) to prioritize the monitoring items of sensing technology developments, (2) to study technological feasibilities, and (3) to discover the killer application which expands ripple effects on economy. To achieve these objectives, final monitoring items were derived from the business analysis of the water supply, the local government survey, the hearing expert opinions and so on. The priority order of final monitoring items were technology developments of (1) the flowmeter flux, (2) the water leakage/crack, (3) the pressure of water supply pipes, and (4) the flux of filtration plants. The research significance is obtained from the derivation and the evaluation of the priority order and the actual demand for the water supply facility management. And, the research results will contribute to the strategic planning for the underground facility intelligence.
김정훈,이나리,신현규,서창섭,Kim, Jung-Hoon,Lee, Nari,Shin, Hyeun-Kyoo,Seo, Chang-Seob The Korean Medicine Society for the Herbal Formula 2014 大韓韓醫學方劑學會誌 Vol.22 No.2
Objectives : Gwakhyangjeonggi-san (GJS) which consists of 13 herbal medicines has been used to treat gastrointestinal disorders caused by common cold. This study was performed to compare GJS decoctions produced using different pressure levels for various extraction times. Methods : Decoctions were prepared by the pressure levels of $0kgf/cm^2$ (non-pressurized) or $1kgf/cm^2$ (pressurized) for 30-180 min. The extraction yield, total soluble solid content (TSSC), and hydrogen ion concentration (pH) were measured, and the contents of the nine marker compounds were determined using high performance liquid chromatography. Results : The higher pressure and longer extraction time significantly increased TSSC value, while decreased the pH value. However, only extraction time affected the extraction yield of pressurized decoction. Variation of the amounts of chemical compounds was shown in pressurized and non-pressurized decoctions during extraction time. The result of regression analysis showed that pressure and extraction time can influence to extraction yield, TSSC, pH, and the content of chemical compounds. Conclusions : This study suggests that the pressure and extraction time can significantly affect the extraction efficiency of components from GJS decoctions.
열보호재료의 열 및 물질전달 현상에 관한 수치해석적 연구
김정훈,권창오,서정일,배철호,송동주,Kim, Jung-Hoon,Kwon, Chang-Oh,Seo, Jeong-Il,Bai, Cheol-Ho,Song, Dong-Joo 대한기계학회 1999 大韓機械學會論文集B Vol.23 No.9
A numerical analysis is performed to predict the thermal response and ablation rate for charring or non-charring material which is designed to be used as thermal protection system (TPS). The numerical program composed of in-depth energy balance equation and the aerotherm chemical equilibrium (ACE) program. The ACE program calculates various thermochemical state from ablation products. The developed numerical program is verified by comparing the reported results from literature. The sensitivity tests for input parameters are performed. The thermal behavior of ablating material is mainly affected by density of ablating material, convective heat transfer coefficient and recovery enthalpy of flow field.