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부식제에 의한 위장관 손상 환자에서 상부 위장관 조영술 후 발생한 위유문부 폐쇄 1례
김정구,조혜진,이승희,김범수,노형근,Kim, Jeong-Goo,Cho, Hye-Jin,Lee, Seung-Hee,Kim, Pum-Soo,Roh, Hyung-Keun 대한임상독성학회 2003 대한임상독성학회지 Vol.1 No.1
Caustic ingestion can produce a progressive and devastating injury to the esophagus and stomach, In the acute stage, perforation and necrosis may occur. Long-term complications include esophageal stricture, antral stenosis and the development of esophageal cancer. Endoscopy should be performed as soon as possible in all cases to evaluate the extent and severity of damage, unless there is evidence of perforation. Endoscopy is the diagnostic procedure of choice. However, when the endoscopy cannot be passed through due to esophageal stricture, upper GI barium studies may be useful as a follow-up measure and in the evaluation of complications. A 44-year-old man visited our hospital complaining frequent vomiting 1 hour after ingestion of unknown amount of hydrochloric acid. At the time of arrival, the patient's oral cavity was slightly swollen and erythematous. On the endoscopic examination fourteen hour after the caustic ingestion, marked swelling of the arytenoids and circumferential ulceration with brown and black pigmentation at the upper esophagus were observed. Four weeks after the caustic injury, upper esophageal narrowing was observed and then the scope could not be advanced to the stomach. Upper GI barium study performed at that time revealed diffuse luminal narrowing of the esophagus and concentric luminal narrowing from prepyloric antrum to pylorus with disturbance of barium passage. At a week after the Upper GI study, through endoscopic examination after bougie dilatation of the esophagus, barium impaction in the stomach and the pylorus was noticed.
A Clinical Analysis of 100 Cases of Gasless Endoscopic Thyroidectomy
Jeong Soo Kim(김정수),Chung Goo Kim(김정구),Kee Hwan Kim(김기환),Chang Hyuck Ahn(안창혁),Hae Myung Jeon(전해명),Keun Woo Lim(임근우),Eung Kook Kim(김응국),Chung Soo Chun(전정수),Jai Hak Lee(이재학),Hyun Shik Son(손현식),Jung Min L 대한외과학회 2002 Annals of Surgical Treatment and Research(ASRT) Vol.63 No.1
점막하 침윤 조기위암에서 Vascular Endothelial Growth Factor (VEGF)-C와 VEGF-D의 발현
김정구(Jeong Goo Kim),최명규(Myung Gyu Choi),박원상(Won Sang Park),이상철(Sang Chul Lee),이동호(Dong Ho Lee),유영경(Young Kyoung You),안창준(Chang Joon Ahn),박조현(Cho Hyun Park) 대한외과학회 2008 Annals of Surgical Treatment and Research(ASRT) Vol.74 No.1
Purpose: Vascular endothelial growth factor (VEGF)-C and VEGF-D are considered novel growth factors that potentially induce lymphangiogenesis and hyperplasia of lymphatic vessels. The aim of this study was to investigate whether the expressions of VEGF-C and VEGF-D are associated with the clinicophathologic factors, and particularly lymphatic invasion and lymph node metastasis, in early gastric cancers that’s invaded the submucosa. Methods: Using immunohistochemical staining, we studied the VEGF-C and VEGF-D expressions in the gastric cancer specimens from 83 patients who underwent curative gastrectomy. Results: The VEGF-C and VEGF-D immunoreactivity was mainly located in the cytoplasm of the tumor cells. There was a positive VEGF-C expression in 27 of 83 cases (32.5%). The VEGF-D positivity rate was lower than the VEGF-C positivity rate. VEGF-D was positive in 20 of 83 cases (24.0%). A VEGF-C positive expression was associated with lymphatic invasion (P=0.018) and lymph node metastasis (P=0.001). However, the expression of VEGF-D had no correlation with any of the clinicopathologic factors, including lymphatic invasion and lymph node metastasis. Conclusion: The VEGF-C expression may have a role in lymph node metastasis of gastric cancer cells. The VEGF-C expression in tumor specimens may be a reliable marker for lymph node metastasis of early gastric cancer that’s invaded the submucosa.