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반복적인 호흡기 감염과 천식 악화가 동반된 IgG3 아형 결핍증 성인 환자에서 intravenous immunoglobulin 사용 1예
이홍열 ( Hong Yeul Lee ),윤상원 ( Sang Won Yoon ),김영 ( Young Kim ),조환준 ( Hwan Jun Cho ),이주영 ( Joo Young Lee ),구강모 ( Kang Mo Gu ),박태연 ( Tae Yun Park ),최재철 ( Jae Chol Choi ),신종욱 ( Jong Wook Shin ),김재열 ( Jae Y 대한천식알레르기학회(구 대한알레르기학회) 2016 Allergy Asthma & Respiratory Disease Vol.4 No.3
The IgG subclass deficiency is defined as a significant decrease in the serum concentrations of one or more subclasses of IgG in a patient whose total IgG concentration is normal. IgG subclass deficiency can predispose to recurrent sinopulmonary infections. A 29-year-old female patient with a 4-year history of bronchial asthma presented with cough, sputum, dyspnea, and recurrent respiratory infections. She had frequently been treated with antibiotics and systemic steroids for recurrent respiratory infections and acute asthma exacerbations. Chest X-ray and computed tomography showed pectus excavatum and bronchial wall thickening without lung parenchymal abnormalities. On immunological evaluation, she was found to have a low serum IgG3, with normal total IgG concentration. Under diagnosis of selective IgG3 deficiency, she was started on monthly infusions of intravenous immunoglobulin (IVIG) therapy. The frequency and severity of respiratory infections and acute asthma exacerbations were markedly decreased during 3 years of IVIG therapy. Our case report suggests that a patient who has underlying selective IgG3 deficiency and asthma may benefit from IVIG therapy as this can significantly reduce the incidence and severity of recurrent respiratory infections and acute asthma exacerbations. (Allergy Asthma Respir Dis 2016;4:225-229)
가스터빈 블레이드 온도 특성 및 코팅층 건전성 평가를 위한 적외선 열화상 카메라 기법 활용
김재열,심재기,최승현,최진호 한국공작기계학회 2008 한국공작기계학회 추계학술대회논문집 Vol.2008 No.-
Key part of main equipment in a gas turbine may be likely to be damaged due to operation under high temperature, high pressure, high-speed rotation, etc. Accordingly, the cost for maintenance increases and the damaged parts may cause generation to stop. The number of parts for maintenance also increases, but diagnostics technology for the maintenance actually does not catch up with the demand. Blades are made of precipitation hardening Ni superalloy IN738 and the like for keeping hot strength. The surface of a blade is thermal-sprayed, using powder with main compositions such as Ni, Cr, Al, etc. in order to inhibit hot oxidation. Conventional regular maintenance of the coating layer of a blade is made by FPI(Fluorescent Penetrant Inspection) and MTP(Magnetic Particle Testing). Such methods, however, are complicated and take long time and also require much cost. In this study, defect diagnostics were tested for the coating layer of an industrial gas turbine blade, using an infraredthermography camera. Since the infrared thermography method can check a temperature distribution on a wide range of area by means of non-contact, it can advantageously save expenses and time as compared to conventional test methods. For the infrared thermography method, however, thermo-load must be applied onto a tested specimen and it is difficult to quantify the measured data. To solve the problems, this essay includes description about producing a specimen of a gas turbine blade (bucket), applying thermo-load onto the produced specimen, photographing thermography images by an infrared thermography camera, analyzing the thermography images, and pre-testing for analyzing defects on the coating layer of the gas turbine blade.