쥐의 포르말린 시험에서 척수강 Sildenafil의 항통각효과에 대한 GABAB 수용체 조절성

김웅모 ( Woong Mo Kim ),윤명하 ( Myung Ha Yoon ),이형곤 ( Hyung Gon Lee ),한용구 ( Yong Gu Han ),김여옥 ( Yeo Ok Kim ),황란희 ( Lan Ji Huang ),최금화 ( Jin Hua Cui ) 대한통증학회 2007 The Korean Journal of Pain Vol.20 No.2

시흥·안산 산단 및 영향지역의 휘발성유기화합물질(VOCs) 분포 특성

김동기(Dong-Gi Kim),우정식(Jung-Sik Woo),한현수(Hyun-Su Han),김용준(Yong-Jun Kim),김웅수(Woong-Soo Kim),홍순모(Soon-Mo Hong),김종수(Jong-Soo Kim),윤미혜(Mi-Hye Yoon) 한국환경보건학회 2020 한국환경보건학회지 Vol.46 No.3

Objectives: The concentrations and distribution characteristics of volatile organic compounds (VOCs) in an industrial complex and surrouding affected residential areas were investigated in an effort to support the efficient management of VOCs. Methods: The atmospheric concentrations of VOCs were analyzed at sites around the Sihwa-Banwol complex located in the cities of Siheung and Ansan and in the surrounding affected residential areas. The appearance of VOCs and the characteristics of their temporal and spatial distribution were evaluated. Results: The total VOC concentrations in the industrial complex were detected at 1.9-2.3 times higher than in the affected areas, but the daily VOCs distributions showed similar patterns in both sites. In particular, it was confirmed that the composition ratio of the VOCs and concentration fluctuations over time in the affected areas are similar to those in the adjacent industrial complex. VOC levels in the affected areas were higher than in residential areas in cities without an industrial complex. Conclusions: VOCs in residential areas near an industrial complex were highly distributed due to the influence of continuous pollutant emissions from the industrial complex. Therefore, the management of VOCs in the atmosphere of the affected area is important for identifying and managing the sources of VOCs detected in high concentrations in the industrial complex.

都心地 發破에서의 地盤振動 測定에 關한 鼎究

김웅수(Woong-Soo Kim),이경운(Kyoung-Woon Lee),림한옥(Han-Uk Lim),서백수(Baek-Soo Suh) 강원대학교 산업기술연구소 1983 産業技術硏究 Vol.3 No.-

국내 지역 공항개발 타당성 분석에 관한 연구 -서산 지역 공항개발 분석 사례를 중심으로-

김웅이 ( Woong Yi Kim ),한경근 ( Kyoung Keun Han ) 한국항공운항학회 2008 한국항공운항학회지 Vol.16 No.4

As the low-cost carriers of the region enters the air transportation market, the domestic air transport circumstance is to be changed and each local autonomous entity conducts the feasibility study to develop the regional airport. But the airport is developed almost all by the goal of the policy and actually the valid basis of the airport development is often weak. To present the validity of the regional airport development Using the pre-feasibility study method the government performs I apply it to the airport development project of the Seo-san region. To present the validity of the regional airport development this study carries out the pre-feasibility study by the AHP analysis.

해외파견인력의 적응에 대한 갈등관리의 영향

김웅기(Woong Ki Kim),한태영(Tae Young Han) 한국인사관리학회 2012 조직과 인사관리연구 Vol.36 No.2

본 연구의 목적은 해외파견인력의 갈등관리와 비교문화역량의 영향을 통하여 현지 파견적응에 이르는 과정을 밝히는데 있다. 또한 해외파견인력에 대한 현지 팀의 파견지원이 개인 선행변인들 간의 관계에 미치는 교차수준 조절효과를 검증하였다. 국내기업의 10개 국가에 진출한 31개 해외지사에 소속된 41개 팀의 근로자 164명을 대상으로 설문조사를 실시하였으며, 여기에는 해외파견인력 120명과 현지채용인력 44명이 포함되었다. 다수준(multi-level) 방법론을 활용한 분석한 결과, 개인수준에서 해외파견인력의 갈등관리 행동 및 비교문화역량과 파견적응 간의 관계가 정적으로 나타났으며, 개인수준의 매개효과 검증을 통하여 갈등관리가 파견적응에 미치는 영향에서 비교문화역량이 부분매개역할을 하는 것으로 나타났다. 그리고 해외파 견인력의 갈등관리-비교문화역량의 관계에서 해외파견인력에 대한 현지 팀 파견지원의 교차수준 조절효과가 정적으로 유의하게 나타났다. 이러한 결과를 바탕으로 해외파견인력이 현지에 적응하는 과정에 대하여 이론적으로 논의하고 해외파견인력의 적응수준을 향상시키는데 필요한 개인과 팀의 역할에 대한 시사점과 미래연구를 제시하였다. The purpose of this study was to identify the process of expatriate adjustment from conflict management via cross-cultural competencies and to examine the influence of team characteristics on the relationship between expatriate adjustment relevant antecedents. Specifically, this study examined the mediating effect of cross-cultural competencies between conflict management effectiveness and expatriate adjustment at the individual level. The study also examined the cross-level moderating effect of team support for expatriates on the relationship between conflict management effectiveness and cross-cultural competencies. The study conducted a survey research method using a data collected from 120 expatriates and 44 local employees of 41 teams in 22 Korean companies and 31 overseas branch across 10 countries. The results of the study found positive effects of conflict management and cross-cultural competencies on the expatriate adjustment at the individual level. The mediation analyses showed a partial mediation effect of cross-cultural competencies between conflict management and expatriate adjustment at individual level. This study also found a positive moderating effect of team support in a way that effective conflict management of expatriates with higher level of team support were better in learning and implementing cross-cultural competencies that affect expatriate adjustment. From the results, theoretical and practical implications were discussed.

대동맥판역류증과 좌심실수축말기용적 확장이 있는 환자에서 좌심실최고수축기압/수축말기용적비와 판막치환후의 증상적 호전과의 관계

김웅한,안혁,Kim, Woong-Han,Ahn, Hyuk 대한흉부심장혈관외과학회 1996 Journal of Chest Surgery (J Chest Surg) Vol.29 No.8

이 연구는 대동맥판역류증이 있으면서 좌심실수축말기용적(left ventricular end-systolic volullle)이 커져있는 환자에서 수술전 좌심실 최고수축기압수축말기용적비(left ventricular peak systolic presslle/end-systolic volume ratio)를 판막치환후의 증상적 호전 판단의 자료로서의 적용 여부를 검토하기위한 것이 다 대상은 중정도 이상의 대돈맥판역류증이 있고다른 심혈관계의 이상이 없으면서 좌심실수축말기용적이 60mm2 넘는 21명(남 15, 여 6, 15까에서 60세가지 연령 분포)이었다. 이들을 대상으로 심도자시 통 상적으로 측정하는 여러 변수와 판막치환후 증상적 호전과의 관계에 대해서 분석하였다. 수술 6개월후 증세의 호전이 13명(62%)의 환자에서 있었고, 8명(38%)에서는 증세의 변화가 없었다. 복합변수분석을 통해서 좌심실최고수축기압$\boxUl$수축말기 용적 비는 통계적으로 유의하게 수술 a개월후의 기능적분류상태(p=0.005)와 수술전에 비해 수술 6개월후 기능적분류상태의 변화 정도(p=0.032)를 판단 하는 지표임을 나타냈었다. 판막치환 6개월후 비가 1.71 mmHg/ml/m2 이상되는 모든 환자는 기능상태 I 혹은 II를 유지한 반면 비가 1.71 mmHg ml/m2 미만인 환자에서는 40%가 기능적분류상태 III이 있다. 좌심실 수축말기 용적이 60 ml/m2 이상 커져 있는 대동맥 판역류증 환자에서 좌심실최고수축기 압1수축 말기용적비는 판막치환후의 증상적 호전을 예측하는 지표로 사용될 수 있다. This study was designed to assess the left ventricular peak systolic pressure/end-systolic volume (PSP/ESV) ratio in predicting symptomatic improvement with valve replacement in patients with aortic regurgitation and enlarged left von'lrlcular volume. We studied 21 patients (15 men and 6 women aged 15 to 60 years) with moderate or severe aortic regur- gitation, no other cardiovascular abnormalities and left ventricular end-systolic volume over 60 m11m2. In this group we assessed the preoperative variables which routinely were measured at cardiac catheterlzation to predict symptomatic improvement with valve replacement. Six months after operation, symptoms were alleviated in 13 patients(62%), and unchanged in 8()8%). By multivariate analysis, the PSP/ESV rati was a strong predictor for functional class 6 months after surgery(p=0.005) and also for change- in functional class prior to an operation to 6 months postoperatively(p=0.0)2). By 6 months after receiving valve replacement, all patients with a ratio over 1. 71 mmHglml/m'were in functional class I or II , in contrast, of those with a ratio < 1.71 mmHg/ml/m2, 40% were in functional class III. The PSP/ESV ratio may help to predict which patients with aortic regurgitation and enlarged left ven- tricular end-systolic volume will have symptomatic improvement with valve replacement.

후방 대정맥-우심방 우회술에 의한 하대정맥 미만성 폐쇄의 치험 2

김웅한,안혁,Kim, Woong-Han,Ahn, Hyuk 대한흉부심장혈관외과학회 1993 Journal of Chest Surgery (J Chest Surg) Vol.26 No.12

Two patients with chronic Budd-Chiari syndrome resulting from segmental obstruction of the inferior vena cava underwent operation. There were 1 man and 1 woman. The obstructed segment was directly visualized by a transthoracic, transdiaphragmatic, retroperitoneal approach. In these two cases, severe segmental obstruction of the inferior vena cava was observed just above the right hepatic vein. These patients underwent successful retrohepatic cavoatrial bypass with a polytetrafloroethylene [PTFE] graft [ 16mm plain and 16mm ringed graft ]. There were no operative mortality and postoperative complication. These patients have been followed up for 6months and 36months without evidence of re-obstruction. When there is a severe stricture of the IVC with hepatic veins draining freely into the obstructed segment of the IVC, a dorsal cavoatrial bypass with a PTFE graft, preferably ringed, is the method of choice.

쥐의 포르말린 시험에서 척수강 Sildenafil의 항통각효과에 대한 GABA_B 수용체 조절성

김웅모,윤명하,이형곤,한용구,김여옥,황란희,최금화,Kim, Woong Mo,Yoon, Myung Ha,Lee, Hyung Gon,Han, Yong Gu,Kim, Yeo Ok,Huang, Lan Ji,Cui, Jin Hua 대한통증학회 2007 The Korean Journal of Pain Vol.20 No.2

Background: A phosphodiesterase 5 inhibitor, sildenafil, has been effective against nociception. Several lines of evidence have demonstrated the role of the GABAergic pathway in the modulation of nociception. The impact of the GABA receptors on sildenafil was studied using the formalin test at the spinal level. Methods: Male SD rats were prepared for intrathecal catheterization. The formalin test was induced by subcutaneous injection of formalin solution. The change in the activity of sildenafil was examined after pre-treatment with GABA receptor antagonists ($GABA_A$ receptor antagonist, bicuculline; $GABA_B$ receptor antagonist, saclofen). Results: Intrathecal sildenafil dose-dependently attenuated the flinching observed during phase 1 and 2 in the formalin test. The antinociceptive effect of sildenafil was reversed by the $GABA_B$ receptor antagonist (saclofen) but not by the $GABA_A$ receptor antagonist (bicuculline) in both phases. Conclusions: Intrathecal sildenafil suppressed acute pain and the facilitated pain state. The antinociception of sildenafil is mediated via the $GABA_B$ receptor, but not the $GABA_A$ receptor, at the spinal level.

國産 火藥類의 種類에 따른 發破 振動値의 比較

Han Uk Lim(林漢旭),Woong Soo Kim(金雄秀),Kyoung Woon Lee(李慶雲) 강원대학교 산업기술연구소 1985 産業技術硏究 Vol.5 No.-

The blast-induced ground vibrations is one of the most important factors which is considered to design blasting patterns in urban excavation. To compare with vibration level of different explosives, peak particle velocity of each explosive was measured. The results are summerized as follows. 1. Among the three kinds of explosives, the largest vibration was obtained from the gelatine dynamite, while the smallest was blasting of ammonium nitrate. 2. The vibration levels of ammonim nitrate and slurry explosive were smaller about 35%, 20% respectively than that of gelatine dynamite.

단일 관상동맥 기형이 동반된 급성 대동맥박리의 수술치험

김웅한,안현,Kim, Woong-Han,Ahn, Hyuk 대한흉부심장혈관외과학회 1994 Journal of Chest Surgery (J Chest Surg) Vol.27 No.12

Emergency operation was performed in a patient with severe aortic insufficiency caused by type A acute aortic dissection with aberrant high take-off origin of single coronary artery. The single coronary artery was found to arise from an unusual position high in the ascending aorta. Dissection was begun in the aortic root and involved the single coronary ostium. Valve competance was restored by resuspension of the commissures. the false lumen was obliterated with strips of Teflon felt and surgical glue. The aortic tissues were firmly reinforced and sutured. The proximal aortic stump was anatomically reconstructed, and fortunately the aortic valve was preserved and coronary reimplantation avoided. The patient was discharged at postoperative 13 days without specific complications. Postoperative course during the 18 months follow-up was uneventful.