에스트로겐 수용체 양성 MCF-7 유방암 세포주에 대한 costunolide의 항암효과

김운지(Woon Ji Kim),최윤경(Youn Kyung Choi),우상미(Sang Mi Woo),박남규(Nam Gyu Park),정혜인(Hye In Jung),김용국(Yong Gook Kim),신용철(Yong Cheol Shin),고성규(Seong Gyu Ko) 한의병리학회 2013 동의생리병리학회지 Vol.27 No.3

지적장애인의 비만 관리 프로그램 효과: 메타분석-국내 연구를 중심으로-

김운지 ( Kim Woon-ji ),박은영 ( Park Eun-young ) 대구대학교 특수교육재활과학연구소 2017 특수교육재활과학연구 Vol.56 No.3

이 연구는 메타분석을 통해 지적장애인을 대상으로 한 비만 관리 프로그램의 효과를 알아보는데 그 목적이 있었다. 이를 위해, 지적장애인을 대상으로 한 비만 관리 프로그램 적용연구 중 단일집단 사전-사후 설계를 적용한 연구와 실험집단과 통제집단 사전-사후 설계를 적용한 연구를 선별하였다. 하위 요소별 분석결과는 다음과 같았다. 첫째, 종속변인에 따른 효과크기 측정 결과, 신체 조성은 체지방률(ES = -1.351), 체력은 심폐지구력(ES = 1.249), 혈중 지질은 LDL-C(ES = -1.434)의 효과크기가 가장 큰 것으로 나타났다. 둘째, 연구 설계에 따른 효과크기 측정 결과, 표집 방법은 무작위 실험연구(ES = -0.369)가 유의한 효과크기를 보였으며, 실험 설계는 통제집단 실험연구(ES = -0.281)가 유의한 효과크기를 보였다. 셋째, 운동 유형은 유산소 운동(ES = -0.204)이 유의한 효과크기를 보였다. 넷째, 중재 환경 중 중재 기간은 21주 이상(ES = -0.567), 중재 시간은 41-50분(ES = -0.370), 학교급은 성인(ES = -0.348)의 효과크기가 가장 큰 것으로 나타났다. 이 연구는 메타분석을 통해 지적 장애인의 비만 관리 프로그램의 내용과 종속변인 등에 따른 효과크기를 종합적으로 분석하여 비만 관리 프로그램의 실제적인 유용성을 확인하였다는데 그 의의가 있다. The purpose of this study was to investigate the effects of obesity management program for people with intellectual disabilities through meta-analysis. For that purpose, the investigator selected researches that applied an obesity management program to individuals with intellectual disabilities with a one group pretest-posttest design or experiment-control group pretest-posttest design. The analysis results by the subelements were as follows: first, the study measured effect sizes according to dependent variables and found that the body fat percentage, cardiovascular endurance, and LDL-C recorded the biggest effect size in body composition, physical strength, and blood lipid, respectively. Second, the measurements of effect size according to research designs indicate that there were significant effect sizes according to random experimental researches in terms of sampling methods and control group experimental researches in terms of research designs. Third, there were no significant effect sizes in case of anaerobic exercise and also a combination of anaerobic exercise and aerobic exercise. Significant effect sizes were found in case of aerobic exercise. Finally, the effect size was the biggest when the intervention period was 21 weeks or more, the intervention duration was 41~50 minutes in terms of intervention environment and when the school class was for adults. The present study holds its significance in that it conducted total analysis of obesity management programs for people with intellectual disabilities in content and effect sizes according to dependent variables through meta-analysis, thus confirming the actual usefulness of obesity management programs.

지적장애 분야에서 출판된 비무작위 연구의 방법론적 질 평가

김운지 ( Woon-ji Kim ),송민철 ( Min-chul Song ),김선옥 ( Sun-ok Kim ),박은영 ( Eun-young Park ) 한국지적장애교육학회(구 한국정신지체아교육학회) 2016 지적장애연구 Vol.18 No.2

이 연구는 지적장애 분야에서 출판된 논문 중 비무작위 연구들을 방법론적 측면에서 분석하여 질적 수준을 알아보는 데 목적을 두었다. 이를 위해 비무작위 연구 101편을 MINORS의 분석기준에 따라 평가하고 질적 수준이 연구특성에 따라 차이가 있는지 알아보았다. 연구특성은 대상 연령, 연구 주제, 연구 환경, 출판 연도로 알아보았다. 질적 수준 평가 결과 문항의 전체 평균점수는 1.48점, 표준편차는 0.61점으로 나타났다. 연구 대상의 연령에 따른 질적 수준 평균 점수는 유.초는 12.66점, 중.고는 13.07점, 성인은 12.06점이었고 통계적으로 유의한 차이는 없었다. 연구 주제에 따른 질적 수준 평균 점수는 학습은 13.47점, 운동은 11.93점,적응행동은 13.00점, 치료는 12.42점이었고 통계적으로 유의한 차이는 없었다. 중재 환경에 따른 질적 수준 평균 점수는 학교는 13.10점, 지역사회는 12.31점, 치료실은 12.20점, 기타는 12.20점이었고 통계적으로 유의한 차이는 없었다. 연도에 따른 질적 수준 평균 점수는 2006-2008년은 12.38점, 2009-2011년은 12.93점, 2012-2015년은 12.80점이었고 통계적으로 유의한 차이는 없었다. 이 연구는 지적장애 분야 비무작위 연구의 방법론적 질 제고를 위한 방안을 모색하고 근거기반 중재를 위한 기초자료를 제시하는 데 그 의의가 있다. The purpose of this study was to examine the quality features of non-randomized studies in published thesis in a field of mental disability through methodology analysis. For this, the quality features of 101 non-randomized studies were evaluated by the criterion of MINORS and it was concluded that whether there was a significant difference of quality features according to the research characteristics. The research characteristics was examined according to the object age, the research subjects, the research settings and published year. The overall average of the quality evaluation was 1.48 points, the standard deviation was 0.61 points. The average quality score based on age of the study is a group of kindergarten & elementary school, middle & high school, and adults scored 12.66, 13.07, and 12.06, respectively. The score of middle & high school was no statistical significance. The average quality score of the research topic is the score of learning, exercise, adaptive behavior, and therapeutics was 13.47, 11.93, 13.00, and 12.42, respectively. The learning field score was no statistical significance. The average quality sore of the research settings is the score of school, local community, treatment room, and etcetera was 13.10, 12.31, 12.20, and 12.20, respectively. The score of school was no statistical significance. There are no significant differences in level of quality according to published year. This study might have implication for looking for ways to improve the methodological quality of non-randomized studies and for providing basic data for evidence-based interventions in field study related to mental retardation.

과학신문을 활용한 과학 글쓰기 프로그램이 지적장애 학생의 과학 글쓰기 및 과제수행행동에 미치는 효과

김선옥 ( Kim Sun-ok ),이옥인 ( Lee Ok-in ),송민철 ( Song Min-chul ),김운지 ( Kim Woon-ji ) 한국특수아동학회 2016 특수아동교육연구 Vol.18 No.4

연구목적: 이 연구에서는 고등학교에 재학 중인 지적장애 학생에게 과학신문을 활용한 과학 글쓰기 프로그램이 학업성취 및 과제수행행동에 어떠한 효과를 미치는지 알아보았다. 연구방법: 중재의 효과검증을 위해 D시, J시에 위치한 2개의 특수학교 고등학교와 공립 고등학교에서 시간제 특수교육을 받고 있는 지적장애 학생 3명에게 대상자간 중다 기초선 설계를 적용하였다. 중재로 투입된 과학신문을 활용한 과학 글쓰기 프로그램 내용은 「2011 개정 특수교육 기본교육과정」고등학교 과학과 학습내용과 연계되어 있으며, 참여한 지적장애 학생들의 능력과 흥미를 고려한 내용을 인터넷상의 과학 신문에서 발췌하여 재구성하였다. 중재의 효과크기 분석은 기초선과 중재 간평균, 범위, 경향선, PND값, Tau-U를 산출하였으며, 유지구간의 평균, 범위, 경향선을 산출하였다. 연구결과: 참여자별 과학 글쓰기 성취 결과는 세 명 학생 모두 중재효과가 있는 것으로 나타났으며, 유의미한 차이가 있는 것으로 나타났다. 또한 중재효과는 유지되고 있는 것으로 나타났다. 과제수행행동 결과도 세 명 학생 모두 중재효과가 있는 것으로 나타났으며, 유의미한 차이가 있는 것으로 나타났다. 결론: 학생 A와 B는 중재효과가 유지되었으며, 학생 C는 유지구간에 중재효과가 향상된 것으로 나타났다. Purpose: The purpose of this research was to examine how a science writing program using scientific articles affects academic achievement and on-task behavior of high school students who have intellectual disability. Method: A multiple baseline design across participants was applied to three students with intellectual disabilities who are enrolled in part-time special education classes of two different types of schools to verify the intervention effects; One is a school and another is a high school located in city D and J. The intervention contents applied to a science writing program using scientific articles were connected to learning contents of the 「Revised Basic Curriculum for Special Education in 2011」policy for high school science courses. The contents were extracted and restructured from online scientific articles based on abilities and interests of students with intellectual disabilities who participated in the research. Through effect-size analysis for the intervention, base line, means between the interventions, range, trend line, PND value, and Tau-U value were calculated and means, range, trend line during the sustain period were calculated. Results: The results of the science writing achievement for each participant indicated that all the three students had an intervention effects, and significant differences. Moreover, it showed that the intervention effects were still maintained. The on-task behavior results showed that all the three students had intervention effects and signifiant differences. Conclusion: The intervention effects of student A and as student B were also maintained, and the intervention effects of student C were improved during the maintain period.

「각급학교 내 장애인 일자리사업」운영실태 분석

서화자 ( Seo Hwa Ja ),김운지 ( Kim Woon Ji ),이은진 ( Lee Eun Jin ) 대구대학교 특수교육재활과학연구소 2014 특수교육재활과학연구 Vol.53 No.4

이 연구는「각급학교 내 장애인 일자리 사업」을 운영과정에서 특수학교 담당교사들이 당면하기 쉬운 문제들의 개념을 범주화 및 유형화하고 탐색해보고자 실시되었다. 연구대상은「각급학교 내 장애인 일자리 사업」업무를 담당하고 있는 전라북도 내 특수학교 교사들로 근거이론 방법을 적용하여 면담자료를 분석했다. 연구결과는 다음과 같다. 첫째,「각급학교 내 장애인 일자리 사업」운영 과정에서 나타난 개념은 총 136개이며, 이를 통합한 하위범주는 45개이고, 이는 다시 11개의 상위범주로 통합되었다. 둘째,「각급학교 내 장애인 일자리 사업」운영 과정에서 나타난 중심현상은 ‘업무부담’과 ‘업무에 대한고민’이었다. 이에 작용하는 인과적 조건은 ‘일자리사업의 필요성’과 ‘업무 운영’ 이며, 맥락적 조건은 ‘환경적 어려움’과 ‘부족한 인적지원’ 이었고, 작용/상호작용 전략에 대한 중재적 조건의 결과는 ‘제도개선 요구’와 ‘정책 확립의 필요성’으로 도출되었다. 셋째, 패러다임 모형에 따라 연구 대상별「각급학교 내 장애인 일자리 사업」운영의 유형은 맥락적 조건과 중재적 조건에 따라 ‘극복형’, ‘순응형’, ‘혼란형’ 세 가지 유형이 존재하였다. 이러한 결과는「각급학교 내 장애인 일자리 사업」운영과정에서 담당교사들이 당면하는 문제들을 이해하고, 업무운영과 연관된 직무진행 및 일자리 사업운영의 질적향상을 위한 면밀한 계획을 세우고 실천해 나가는데 도움을 줄 수 있을 것이다. The purpose of this study was to profoundly examine the problems facing the special teachers charged with the duties related to the operation of ``Job Creation Project for the Disabled in School``. The subjects of this study was the special teachers responsible for the operation for the ``Job Creation Project for the Disabled in School`` in North Jeolla Province, and the data were collected through individual interview. The foundation theory approach method, presented by Strauss and Corbin(1998), was used. Based on the results of this study, a total of 136concepts, 45sub-categories, and 11 categories were derived in relation to the special teachers`` operation of ``Job Creation Project for the Disabled in School``. The special teachers`` operation of tasks related to the ``Job Creation Project for the Disabled in School`` was found to focus on the ``workload`` and ``concern about the works`` which were the main phenomenon of the operation. The causal conditions that led to the main phenomenon were found to be the ``necessity of the job creation project`` and ``operation of tasks``. Meanwhile, the ``environmental difficulties`` and ``inadequate manpower support`` were the environmental factors affecting the main phenomenon. The mediation situation factors affecting the resolution of main phenomenon in relation to the ``Job Creation Project for the Disabled in School`` were found to be the ``positive factors`` and ``negative factors``. The ``effort for the cooperative system`` was found to be the strategy to resolve the main phenomenon of the operation of ``Job Creation Project for the Disabled in School``, and the resultant outcomes were found to be the ``necessity for establishment of policies`` and ``demand for improvement of system``. The results from the analysis of operation processes of ``Job Creation Project for the Disabled in School`` were summarized to be the phase of implementation, phase of conflict, phase of adjustment, and phase of demand. 3types, i.e., overcome type, adaptation type, and confusion type, were presented for the foundation theory for the operation of ``Job Creation Project for the Disabled in School``. Based on the results of research, this study presented the recommendation for the succeeding studies, along with the discussion related to the special teachers`` operation of ``Job Creation Project for the Disabled in School``.

강우시 유출부하량을 이용한 팔당상수원 유역의 비점오염원 원단위와 발생량 추정

이현동(Hyun Dong Lee),안재환(Jae Hwan Ahn),배철호(Chul Ho Bae),김운지(Woon Ji Kim) 한국물환경학회 2001 한국물환경학회지 Vol.17 No.3

In the study, unit loading and total loading on landuse types in Paldang watershed were estimated by using runoff loading of nonpoint source on nonurban(Forest/Resort and Rice/Crops area) areas and urban areas. Those areas were selected as river basins that have similar landuse types that could be represented as unit landuse types. Although it was difficult to compare directly unit loading proposed in this study with that used conventionally because of the difference of field investigation. But the results showed that unit loading on landuse types may be included in the range of conventional unit loading. The results also showed that total loading of BOD was 29,085 ton/year in Paldang watershed. The contribution ratio of South Han River in Paldang watershed was about 69%. Among total BOD loading generated of 18,097 ton/year (62%) attributed to loading from urban areas and 5,703 ton/year derived in forest/resort areas. While 5,285 ton/year was loaded in rice/crops areas. In addition, the contribution ratio of total nitrogen (T-N) in urban areas was also higher than other landuse types. On the other hand, the ratio of total phosphorous (T-P) was lower than in all areas. In case of considering total loading generated of point source, the contribution ratios of nonpoint source pollutants such as BOD. T-N, and T-P were 37.8%. 38.4% and 18.5% respectively. Among those pollutants. the contribution ratio T-N was higher than other pollutants.

토지이용별 강우시 비점오염 물질의 유출특성

이현동(Hyun Dong Lee),안재환(Jae Hean Ahn),김운지(Woon Ji Kim),배철호(Chul Ho Bae) 한국물환경학회 2001 한국물환경학회지 Vol.17 No.2

This study carried out to identify the runoff characteristics of non-point source(NPS) pollution in the Paldang reservoir watershed. Several sub-basins were selected and used as the study sub-basins in which major landuse types were different each other. Rainfall, water quality and flow rate were observed by landuse types in the study sub-basins. Peak time of storm water runoff and pollutant concentration showed big differences depending on landuse and rainfall conditions at each corresponding sub-basins. Although slight differences in storm flow rate were observed depending on rainfall, sudden increase and decrease in flow rate were, however, noted in forest/resort and urban areas. While in agricultural areas, the slope of the hydrograph of storm runoff flow increased and decreased gradually. The variation of pollutant concentrations in terms of BOD, COD, SS and T-P was large depending on the flow rate of stormwater. On the other hand, little change of T-N concentration in stormwater was appeared. In forest/resort areas, the BOD load discharged was 1.53 ㎏/ha/day for total rainfall of 140.4 ㎜ during three rainfall. The BOD loading from agricultural areas was 1.93 ㎏/ha/day for total rainfall of 84.9 ㎜. And BOD loading from urban areas was 22.84 ㎏/ha/day for total rainfall of 72.94 ㎜. Although the total rainfall in the urban areas was smaller than other areas, the BOD load attributed to NPS in urban areas was much greater.

한의원에서 사용 가능한 정량적인 월경곤란증 평가지표 개발

박정수 ( Jeong Su Park ),박선주 ( Sun Ju Park ),김경훈 ( Gyeong Hun Gim ),김운지 ( Woon Ji Kim ),최형심 ( Hyeong Sim Choi ),최한석 ( Han Seok Choi ),최윤경 ( Youn Kyung Choi ),조정훈 ( Jung Hoon Cho ),신용철 ( Young Chul Shin ) 대한한방부인과학회 2011 大韓韓方婦人科學會誌 Vol.24 No.1