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      • 영아 담도폐쇄증 진단에서 Tc-99m DISIDA 간담도주사와 경피간침생검의 의의

        김우석,박우현,최순옥,김상표,Kim, Woo-Suk,Park, Woo-Hyun,Choi, Soon-Ok,Kim, Sang-Pyo 대한소아외과학회 1997 소아외과 Vol.3 No.1

        본 저자들은 1992년 3월부터 1996년 4월까지 신생아 울체성 황달의 감별진단, 특히 신생아담도폐쇄증과 신생아 간염의 감별진단에 있어 Tc-99m DISIDA 간담도주사와 경피간침생검을 시행하여 다음과 같은 결과를 얻었다. 질환별로 볼 때 전체 60예의 환아 중에서 담도패쇄증이 23예, 신생아 감염이 34예였으며 경정맥고영양법으로 인한 황달이 2예, Alagille 증후군이 1예였다. Tc-99m DISIDA 간담도주사는 60명의 환아를 대상으로 실시하였다. BA 진단에 대한 민감도와 특이도는 각각 96%와 32%로서 높은 민감도를 보인 반면 특이도는 낮게 나타났으며 전체적인 진단 정확도는 57%였다. 경피간침생검은 Tc-99m DISIDA 간담도주사를 실시한 60명의 환아중 장관내 방사능이 나타나지 않았던 38명의 환아에서 40회 실시하였는데, 경피간침생검에 BA 진단에 대한 민감도는 88%, 특이도는 96%로 모두 높았으며 전체적인 진단 정확도는 93%였다. 본 연구를 요약하면 Tc-99m DISIDA 간담도주사는 특이도 32%, 양성예측율 47%로서 Tc-99m DlSIDA 간담도주사에서 장관내 방사능이 배설이 되지 않을 때는 경피간침생검이 반드시 필요하리라 생각되며, 일단 장관내 방사능이 배출되면 BA는 배제할 수 있으리라 생각된다. 경피간침생검은 전체적인 진단율이 93%로 높으나, BA 환아에서 8주전에 경피간침생검시는 NH와 감별이 어려울 수 있으며, 또 일부 NH, 경정맥고영양법 관련 울체성 황달에서는 경피간침생검시 BA와 감별이 어려울 수 있으므로, 임상경과를 보아서 의심스러우면 재 경피간침생검을 시행하던지 타 진단법을 응용해서 참고하여야 할 것으로 생각된다. To differentiate biliary atresia from intraheaptic cholestasis, Tc-99m DlSIDA hepatobiliary scintigraphies and percutaneous needle biopsies of 60 consecutive infants were evaluated retrospectively. Twenty three patients had biliary atresia and 37 patients intraheaptic cholestasis(neonatal hepatitis 34, TPN induced jaundice 2 and Dubin-Johnson syndrome 1). All sixty patients underwent Tc-99m DlSIDA hepatobiliary scintigraphy with phenobarbital pretreatment. Of 23 patients with biliary atresia, 22 were correctly interpreted showing 96% sensitivity while of 37 patients with intraheaptic cholestasis, only 12 had intestinal excretion of radionuclide showing 32% specificity. Among the forty needle biopsies, 17 of biliary atresia and 23 of intrahepatic cholestasis, 37 were correctly interpreted as either having biliary atresia or intrahepatic cholestasis. The overall diagnostic accuracy was 93%. Of 3 misdiagnosed cases, the histologic findings of two patients with biliary atresia(aged 43 days and 54 days at the first needle biopsy) were essentially the same as those of neonatal hepatitis. Follow-up biopsies, however, showed findings consistent with biliary atresia. The third one(VLBW premie with history of 8 weeks of TPN) showed mild ductal proliferation and portal fibrosis. This was interpreted as suspicious for biliary atresia. Jaundice resolved gradually. In summary, patients who have intestinal excretion of radionuclide on Tc-99m DlSIDA hepatobiliary scintigraphy, biliary atresia can be ruled out. But the patients who do not have intestinal excretion of radionuclide should have further investigation by needle biopsy. Judicious use of Tc-99m DISIDA hepatobiliary scintigraphy and percutaneous needle biopsy can give a diagnostic accuracy of 95% or more in cases of infantile cholestasis.

      • SCOPUSKCI등재

        비분산 적외선 분광법을 이용한 Co<sub>2</sub>농도 고속 분석기의 Sampling Module 특성에 관한 실험적 연구

        김우석,손덕영,박영무,유재석,이종화,Kim, Woo-Seok,Shon, Deok-Young,Park, Young-Moo,Yoo, Jae-Suk,Lee, Jong-Hwa 대한기계학회 2003 大韓機械學會論文集B Vol.27 No.3

        A fast response analyzer for measuring carbon dioxide concentration has been developed for transient characteristic and researches tested on internal combustion engine. The analyzer uses the well known NDIR(Non-Dispersive Infrared) method with miniaturized detection system, giving a time constant of approximately 30 microsecond, and sampling module consists of capillary tube. Since the transit time and the time constant of the sampling system depend on the sampling conditions, it is necessary to investigate the characteristics of sampling system before applied to exhaust gas measurement in engine. A unique method was designed to study the influence of the diameter of transfer sample line and operating conditions of the FRNDIR on transit time and time constant. A database of transit time and time constant was built up for different measured and simulated pressure conditions. The database can be used for correcting eventual $CO_2$ concentration measurement.

      • KCI우수등재

        순환골재를 사용한 고강도 철근콘크리트보의 휨거동에 관한 연구

        김우석,여진동,곽윤근,강현구,홍성걸,Kim, Woo-Suk,Yeo, Jin-Dong,Kwak, Yoon-Keun,Kang, Thomas H.K.,Hong, Sung-Gul 대한건축학회 2012 대한건축학회논문집 Vol.28 No.3

        Currently, approximately 90% of waste concrete is being used solely for landfills. Of the total waste concrete only about 14% is made into aggregate and recycled. Such usage is a very low-efficiency method of recycling these materials, under-utilizing an important and valuable asset. Common engineering practice has thus far failed to promote the design of structural members using recycled aggregates. Moreover, appropriate structural design standards for such materials have not been established, despite the number of domestic research studies which have been, and are being, conducted. Such practices overlook the fact that the recycling of aggregate from demolished concrete structures is both structurally and economically beneficial. In making full use of recycled concrete aggregates (RCA) it is necessary to understand its mechanical properties such as compressive, tensile and flexural strengths, and bond strength, as well as its structural performance. The main objectives of this research study are the investigation of flexural performance and the evaluation of the potential applications of RCA on concrete structures. For this, flexural tests of 12 reinforced high-strength concrete beams with RCA were performed. The current test data were examined in terms of flexural strength, along with the data from previously tested reinforced concrete beams with RCA. It is anticipated that this research will play a role of establishing the structural design standards for concrete members with RCA.

      • KCI등재

        어르신 체육 활동지원 서비스 참여노인의 신체활동에 대한 의미 형성과정

        김우석(Kim, Woo-Suk),강형숙(Jung, Joo-Hyug) 한국체육교육학회 2015 한국체육교육학회지 Vol.20 No.3

        이 연구는 어르신체육활동 지원 사업에 참여하는 노인들을 대상으로 신체활동에 대하여 의미를 형성해 나가는 과정을 규명하여 농촌지역 노인들의 신체활동에 참여를 유도하고 어르신 체육활동서비스 사업의 활성화를 위한 전략을 제공 하는데 목적이 있다. 연구방법은 질적 연구방법을 채택하여 2015년 경기, 충남지역 생활체육회에서 진행하는 어르신체육활동 지원 사업에 참여하는 65세 이상의 노인들을 모집단으로 설정한 후 비 확률표본추출방법 중 편의표본추출방법을 사용하여 연구목적에 맞는 10명의 노인과 이를 지도하는 지도자 2명을 연구대상으로 선정하였다. 자료수집은 2015년 7월 1일부터 8월 10일까지 이야기 식 면담과 반 구조화 설문을 통하여 자료를 수집하였으며 자료 분석은 3단계를 거친 텍스트 분석을 실시하였다. 이와 같은 방법을 통하여 얻어진 결과는 다음과 같다. 첫째, 농촌지역 노인들의 체육활동 참여과정에서 인식하는 신체활동의 의미는 ‘여가에 대한 무의미’, ‘신체활동에 대한 제한된 의미부여’, ‘지역공동체를 통한 관계적 접근’, ‘건강에 대한 갈증’이 발견되었다. 둘째, 농촌지역 노인들의 체육활동 참여를 통해 변화된 신체활동의 의미는 ‘신체활동에 대한 재미요소 발견’, ‘신체적 변화 (운동기술, 수행능력의 향상경험)’, ‘심리적 활력’, ‘지역과 세대를 어우르는 연결망 경험’, ‘새로운 라이프 스타일 발견’, ‘신체활동에 대한 공유된 정서 경험’이 발견되었다. 셋째, 농촌지역 노인들의 체육활동 참여의 의미형성 결과로 나타난 신체활동에 대한 공유된 의미는 ‘통합적 건강증진 활동’, ‘세상과의 소통도구(지역·세대 간 메신저 역할),’ ‘정보 공유의 장’, ‘여가 자본의 확충활동’이 발견되었다. Purpose: This study, targeting elderly participants in elderly sports activity support programs, defines their physical activity meaning formation process so as to encourage rural elderly people to further participate in physical activities and to present strategies designed for invigorating elderly sports activity support programs. Methods: A quality research methodology was adopted. A population of 65-year-old or oder participants in 2015 elderly sports activity support programs organized by Life Sports Associations in rural areas in Gyeonggi and Chungnam was set, and out of the population, ten elderly people deemed suitable for this research purpose and two instructors were sampled using the convenience sampling method of non-probability sampling methods. From July 1 to August 10, 2015, subjects were interviewed using a talk-style method based on a semi-structured questionnaire, and the text of gathered data was analyzed in three stages. Results: The findings of this study are outlined below. First, subjects" perception of the meaning of physical activities included meaninglessness of leisure, limited meaning of physical activities, relational approach through the communities, and thirst for health. Second, subjects" perception of the meaning of changed physical activities through the programs included the discovery of fun elements in physical activities, physical changes (sporting skills, and experience in enhanced performance ability), psychological vitality, and experience of networking with the various communities and generations, the discovery of new lifestyles, and experience of shared emotions about physical activities. Third, subjects" perception of the meaning of physical activities as a result of participation in sports activities included holistic health-improvement activities, a tool of communicating with the world (serving as a messenger to network with various communities and generations), a stage of sharing information, and expanded activities of leisure capital.

      • KCI등재

        제주도에서 분리한 미생물의 수질정화 성능 평가에 관한 연구

        김우석 ( Woo Suk Kim ),박준석 ( Jun Seok Park ),서대석 ( Dae Seuk Seo ),김봉균 ( Bong Kyun Kim ),손승욱 ( Seung Wook Son ),박재로 ( Jae Roh Park ) 한국수처리학회 2016 한국수처리학회지 Vol.24 No.4

        In this study, we collected samples from rivers in Jeju Island and other places where the self-purification capacity of rivers had been recovered by utilizing effective microorganisms(EM). And then after separating microorganisms from among the samples, we evaluated each microorganism’s water purification. In addition, we performed DNA sequencing by means of the 16S rRNA gene (16S rDNA) sequencing method for the identification of microorganisms capable of improving water quality and sought to register gene sequence information in GenBank at the National Center for Biotechnology Information (NCBI). According to the COD experiment results, C1, B4 and C6 showed the average removal efficiency of 21.3, 23.4 and 38.6% respectively. According to the T-N experiment results, the respective strains of B4, B6, M3 and C1 showed the average removal efficiency of 26.8, 34.9, 28.3 and 23.3% respectively. According to the T-P experiment results, the respective strains of B4, B6, C1 and C4 showed the average removal efficiency of 15.0, 19.4, 15.1 and 9.1% respectively. By examining the present study, it is judged that the strain of B6 has the best water purification performance. As a result of its identification, the strain of B6 showed 99.66% similarity to the strain of Bacillus subtilis. Moreover, the gene sequence information was registered in GenBank at NCBI in the USA, thereby being assigned the accession number of ‘KU672511’.

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