양식 넙치에서 분리한 어병세균의 lincomycin에 대한 내성 유전자의 분포

김예지,전려진,이영준,고예진,한소리,김성현,정준범,Kim, Ye Ji,Jun, Lyu Jin,Lee, Young Juhn,Ko, Ye Jin,Han, So Ri,Kim, Sung Hyun,Jeong, Joon Bum 한국어병학회 2022 한국어병학회지 Vol.35 No.1

Lincomycin as one of the lincosamides antibiotics have been mainly used in human and livestock fields, but have not been used in aquaculture. In this study, the distribution of minimum inhibitory concentration (MIC) values against lincomycin and the detection of the macrolide-lincosamide-streptogramin (MLS) resistance gene were confirmed in bacterial pathogens isolated from cultured olive flounder (Paralichthys olivaceus). Of the 107 strains isolated from Jeju, 36 strains of Gram-positive bacteria and 71 strains of Gram-negative bacteria were identified. Most of Streptococcus spp. was found to have a MIC value of less than or equal to 0.5 ㎍/mL, and Edwardsiella piscicida was found to have a MIC value higher than 1,024 ㎍/mL. V. harveyi and V. alginolyticus mostly showed MIC values of 256 ㎍/mL, but V. scophthalmi displayed values of 8~64 ㎍/mL. In the detection of MLS resistance gene, erm(B) was detected in 9 strains of Streptococcus spp., and erm(A) was confirmed in one strain.

한약재 약욕요법이 소아 발열기간에 미치는 영향 : 체계적 문헌고찰 및 메타분석

김예지,박소현,서혜선,박슬기,이선행,이진용,Kim, Ye Ji,Park, So Hyun,Seo, Hae Sun,Park, Sul Gi,Lee, Sun Haeng,Lee, Jin Yong 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.3

Objective The purpose of this study is to evaluate whether herbal bath shortens the duration of pediatric fever. Methods Databases, such as Medline, EMBASE, Cochrane library, OASIS, KISS, KMBASE, CNKI, Wanfang Med Online were used to search randomized controlled trials. Those trials that included children younger than 18-year-old were evaluated for the clinical efficacy of herbal bath in fever by analyzing 'body temperature (BT) drop start time' and 'time to return to normal BT'. Results 12 studies or 1306 participants were analyzed in the study. When applying herbal bath in combination with the controlled treatment, 'BT drop start time' was decreased by 0.11 hours, and 'time to return to normal BT' was decreased by 10.94 hours compared to the controlled group. When comparing herbal bath with tepid bath, 'time to return to normal BT' was reduced by 8.19 hours in herbal bath group. In regards to safety, 3 studies out of 12 studies mentioned about its adverse events: 2 studies did not have any adverse events, and a minor needle-shaped bleeding had occurred in one of the studies. Conclusion Use of herbal bath as a treatment of fever in children was associated with shortened duration of fever. However, cautious interpretation is necessary due to its limited safety data.

완전 무치악 환자들을 위한 보철 수복 시 흡착 의치를 이용한 비교 분석 증례

김예지,송영균,Kim, Ye-Ji,Song, Young-Gyun 대한치과보철학회 2019 대한치과보철학회지 Vol.57 No.4

심하게 흡수된 치조제에서 의치의 유지력을 얻기 어려운 경우, 의치가 불안정하게 되어 의치 사용이 어렵다. 흡착 의치는 의치상 변연부를 가동 점막으로 봉쇄하여 폐구 시에 의치상 내면에 생기는 음압 형성을 통해 더 높은 유지와 안정을 목표로 한다. 본 증례에서는 4명의 환자들이 의치가 헐겁다는 주소로 내원하였다. 의치의 유지력에 대한 높은 요구도를 반영하여 흡착 의치의 개념을 이용하여 유지와 안정을 얻고자 하였다. 무치악 환자들에서 흡착의치를 이용한 보철 수복 시 고려할 사항들에 대하여 비교 분석하여 보고하고자 한다. In patients with severely resorbed alveolar bone, it is difficult to gain retention in denture. Lack of retention makes denture unstable and lead to trouble in using denture. Suction denture seals the entire denture border with movable mucosa and this sealing mechanism forms negative pressure beneath the denture and produce higher retention and stability to denture. In this case, 4 edentulous patients visited for lack of retention with dentures. Considering their high expectation with retention, suction denture concept was used to fabricate retentive and stable denture. The purpose of this case report is to compare and analyze the considerations of suction denture restorations in edentulous patients.

소아 알레르기 결막염의 한의학적 병인, 변증, 치법 및 한약재 선택에 대한 문헌적 고찰

김예지,서혜선,박용석,박슬기,이선행,이진용,Kim, Ye Ji,Seo, Hae Sun,Park, Yong Seok,Park, Sul Gi,Lee, Sun Haeng,Lee, Jin Yong 대한한방소아과학회 2021 대한한방소아과학회지 Vol.35 No.2

Objectives We aimed to understand etiology, pattern differentiation, treatment principle, and the role of selected herbs in the treatment of Korean herbal medicine for allergic conjunctivitis (AC) in children. Methods We searched relevant literature published up to February 20, 2021 through CNKI, using search formula of (SU= '結膜炎'+'conjunctivitis') AND (SU='儿童'+'小儿'+'少儿'+'幼年') AND (SU='治療'+'中医治療'+'中藥'+'中医藥'+'顆粒'+'胶囊'+'自擬'+'湯'+'丸'+'散'+'方'). Results Among 81 searched studies, 9 randomized controlled trials and 1 case report were selected and analyzed. In all studies included, the efficacy of herbal treatment for AC was confirmed, and there was no evidence that herbal medicine treatment has higher risk of developing side effects compared to conventional eye drop treatment. As an etiology, wind (風邪) was observed the most frequently, and Saposhnikoviae Radix (防風) and Schizonepetae Spica (荊芥) were in frequent use to dispel wind (祛風). As visceral pattern identification, spleen (脾) and lung (肺) were two important keywords, and spleen deficiency (脾虛), dampness-heat in the spleen and stomach (脾胃濕熱), lung qi deficiency (肺氣虛) were main pathologic mechanisms. Else, treatments related to liver (肝) and removing dampness-heat (濕熱) were mentioned next. Conclusions This study is significant in that AC in children, which has a lack of research compared to other allergic diseases, has been studied in the contents of Korean medicine and laid foundation that can be used as basic data in the actual clinical field. Based on this study, it is hoped that clinical data of Korean herbal medicine treatment for childhood AC will be further accumulated.

청소년기 우울증의 한약치료에 관한 주제범위 문헌고찰

김예지,서혜선,김상민,이선행,이진용,Kim, Ye Ji,Seo, Hae Sun,Kim, Sang Min,Lee, Sun Haeng,Lee, Jin Yong 대한한방소아과학회 2022 대한한방소아과학회지 Vol.36 No.2

Objectives The purpose of this study was to collect reported but scattered data on herbal medicine treatment for depression in adolescents and young adults and to establish future research directions for this topic. Methods Using the scoping review method, 10 Korean and foreign databases were searched for studies published up to March 22, 2022. Studies targeting children and adolescents diagnosed with depression, studies using herbal medicine treatments, and clinical studies were included. Results Twelve randomized clinical trials, two chart reviews, and six case reports were identified. Frequently used Korean medical patterns, treatment methods, herbal medicines, decoctions, treatment periods, and post-treatment evaluation results were analyzed. Differences in the confirmed results from actual clinical settings were reviewed, and the direction of follow-up research on this topic was suggested. Conclusions This study outlined the results of various levels of clinical research on herbal medicine treatment for depression in adolescents and young adults, showed the clinical availability of herbal medicine, and provided a foundation for future research.

정신치료 수련의 질과 역량에 관한 정신건강의학과 전공의 인식도 조사

김예지(Ye Ji Kim),견영기(Yeong Gi Kyeon),이승재(Seung Jae Lee),전명욱(Myong-Wuk Chon),이상원(Sang Won Lee),정성원(Sung Won Jung),이강욱(Kang Uk Lee),대한신경정신의학회 수련위원회(The Committee of Residency Training of the Korean Neurop 대한신경정신의학회 2021 신경정신의학 Vol.60 No.3

Objectives This study surveyed the quality of psychotherapy training and psychotherapy competencies during residency in Korea. Methods A questionnaire developed by The Committee of Residency Training of the Korean Neuropsychiatric Association was completed by fourth-year residents of Korean psychiatry (n=120). The questionnaire examined their demographic characteristics, their experience of clinical psychotherapy training, their degree of satisfaction in the quality of psychotherapy training, and self-rated competence regarding the six types of psychotherapies, including supportive psychotherapy, cognitive behavioral therapy, interpersonal psychotherapy, psychoanalytic psychotherapy, group psychotherapy, and family psychotherapy. Results The degree of satisfaction of the residents with the psychotherapy training was diverse among the types of psychotherapy and contents of training. Across all types of psychotherapies, the satisfaction levels of the quantity and quality of supervision education were low, except for psychoanalytic psychotherapy. Overall, more than 70% of residents were not satisfied with the theoretical education, clinical practice, and supervision education in three types of psychotherapies, including interpersonal psychotherapy, group psychotherapy, and family psychotherapy. A positive correlation was found between the degree of satisfaction with the quality of training experience and self-rated competence of psychotherapy. Specifically, the self-rated competence of psychotherapy was more highly correlated with the experience of clinical cases and supervision than theoretical education Conclusion This study showed the quantitative and qualitative status of psychotherapy training in Korean psychiatry residency programs, and the satisfaction level of psychotherapy education was low except for psychoanalytic psychotherapy. There is a strong need for the improvement of psychotherapy training programs in Korea.

산촌생태관광 도입에 관한 산촌방문객의 인식과 요구 조사

김예지 ( Kim Ye-ji ),김종호 ( Kim Jong-ho ) 한국산림과학회(구 한국임학회) 2018 한국산림과학회지 Vol.107 No.2

본 논문은 산촌지역 방문객을 대상으로 산촌생태관광에 대한 인식 및 요구를 파악하기 위해 설문조사를 실시하였다. 새로운 산촌 정책으로 산촌생태관광을 도입하기 위한 타당성 조사로 산림청의 산촌지역 내 산촌생태마을과 농림축산 식품부의 농촌체험휴양마을을 포함한 57개 산촌 마을의 방문객 439명을 대상으로 2015년 6월 17일부터 9월 17일까지 구조화된 설문지를 이용한 개별면접 설문을 실시하였다. 주요 분석 결과, 산촌생태관광 참여의향에 대하여 Likert 5점 척도로 살펴본 결과, 평균 3.65점으로 산촌생태관광 도입에 대하여 긍정적으로 인식하였으며, 방문횟수는 1년에 1회(44.6%), 1년에 2회(30.1%) 순으로 선호하였다. 또한 희망 방문지역으로 강원도(44.8%)를 가장 많이 응답하였으며, 지불의향은 평균153,320원으로 나타났다. 산촌생태관광 요구사항으로 지역관광 연계 상품 개발(평균 3.99점), 산촌생태관광 프로그램 개발(평균 3.96점) 순으로 응답하였다. 위의 결과들은 산촌생태관광의 가치에 대한 국민들의 인식 강화와 산촌생태관광의 매력성 증대를 위한 소프트웨어 발굴이 필요하다는 것을 시사한다. 이에 따라 산촌생태관광은 지속가능한 산촌이 되기 위한 수단으로 활용될 수 있을 것이다. This study was carried out to investigate the recognition and requirements of mountain eco-tourism by surveying mountain villages’visitors. As a feasibility study to introduce new eco-tourism policies, the individual interview survey was conducted from June 17, 2015 to September 17, 2015 targeting 439 visitors in 57 mountain villages, where the Korea Forest Service designated them as mountain eco-villages and the Ministry of Agriculture, Food and Rural Affairs has been operating the rural experience and recreation village business. As a result of the major analysis, the respondents’intention to participate in mountain eco-tourism was 3.65 by Likert 5-point-scale and the respondent’s most preferred the number of visits was once a year(44.6%) or twice a year(30.1%). Also, the most preferred region was Gangwon-do(44.8%) and the average amount of expense willing to pay was 153,320 won. Lastly, the respondents said they expect development of regional tourism product(M=3.99) and mountain eco-tourism program(M=3.96) by requirements for mountain eco-tourism. This result shows that it is necessary to inspire public awareness regarding the value of mountain eco-tourism and to develop new policies or programs making people more attracted to mountain villages. Thus, it means that mountain eco-tourism can be utilized as a way to steer sustainable mountain village.

유아의 인터넷게임 과몰입에 영향을 주는 유아 개인, 부모 및 가정환경변인 분석

김예지 ( Ye-ji Kim ),김수영(교신저자) ( Soo-young Kim ) 열린부모교육학회 2016 열린부모교육연구 Vol.8 No.2

본 연구의 목적은 유아의 인터넷게임 과몰입에 영향을 주는 유아, 부모 및 가정환경 변인 간의 차이, 관계 및 전체적인 경향을 분석해 보는 것이다. 연구대상은 D시와 K도의 어린이집, 유치원 및 초등학교에 재학 중인 유아 245명이었으며 측정도구는 유아의 인터넷게임 과몰입, 감성지능, 공격성 검사와 부모의 인터넷 중독, 양육태도 검사이다. 자료분석은 t검증, 일원배치분산분석, pearson 상관분석 및 중다회귀분석을 이용하였으며 연구결과는 다음과 같다. 먼저 유아의 인터넷게임 과몰입은 유아 개인변인에서 연령(5,6세/3,4세), 형제관계(형,오빠/누나언니/동생), 감성지능, 공격성이, 부모변인에서는 부모의 인터넷 중독과 가정환경변인에서는 수입구조(외벌이/맞벌이), 가족형태(대가족/핵가족)와 통계적으로 유의한 차이가 나타났으며 부모의 양육태도는 부분적으로 유의함이 나타났으나 유아의 성별과는 유의한 차이가 나타나지 않았다. 또한 유아의 인터넷게임 과몰입과 유아의 개인 및 부모 변인간의 상대적 기여도는 유아의 감성지능, 부모 인터넷 중독, 유아의 공격성 순으로 기여도가 큰 것으로 나타났다. 이러한 본 연구결과는 유아의 인터넷게임 과몰입에 어떤 변인들이 가장 많은 영향을 주는지 밝혀보는 것으로 예방프로그램 계획시 유익한 자료가 될 수 있으리라 사려된다. This study aims at figuring out trends and relations between children``s personal(age, gender, sibling, emotional intelligence and aggression), parental(internet addition of parents and parenting attitude) and familial(family income, family structure) variables affecting internet game overindulgence of children. The research was conducted on total 245 children(boys; 108, girls: 137), consisting of three to six-year-olds who attend children``s center, kindergarten and elementary school in D city and K region. The measuring instrument for the study are children``s internet game overindulgence, children``s emotional intelligence, children``s aggression, Adult Internet Addiction Self-Report Scale(A-Scale), parenting attitude. T-test, ANOVA, Pearson``s correlation analysis, multiple regression analysis were conducted by using SPSS 20.0. The results are as follows: First, depending on age(three, four/five, six years olds), sibling relations of children(older sisters/brothers, younger sisters/brothers), family income(both working/single working), family structure(extended family/core family), children``s emotional intelligence, children``s aggression and parents`` internet addiction, there were significant correlations. Second, there were partly significant correlations between parenting attitude and no significant correlations between gender of children. Parents and teachers should guide children with right internet use and help to make children do safe internet activities.

기울기 기반 허프 변환을 이용한 실시간 차선 검출 시스템 설계

김예지(Ye-Ji Kim),공민성(Min-Seong Gong),박태근(Tae-Geun Park) 대한전기학회 2023 전기학회논문지 Vol.72 No.6

Straight line detection using the gradient-based Hough transform has high accuracy, but has the disadvantage of increased memory and longer processing time due to storing and processing a lot of data. The proposed architecture applies the gradient-based Hough transform algorithm to consider only the points in the range of -4 to +4 centered on the gradient angle in parallel, and increases accuracy by applying the highest weight to the central pixel. In order to improve overall performance, the LUT for the trigonometric functions and voting memory for weight values are divided into 9 parts for each address area, so that the line detection speed is improved by processing data at the same time. The proposed architecture was designed with VerilogHDL and synthesized with DBhitek 110nm standard cell library and the results showed that the maximum operating frequency was 210Mhz (73 fps) with 15K of 2-input NAND gates and 5,950Kb of memory.

증례 : 감염 ; 결핵성 임파선염 환자에서 Rifampin 재투여로 인한 치명적 과민성 반응 1예

김예지 ( Ye Ji Kim ),임선영 ( Sun Young Yim ),배송이 ( Song I Bae ),안재희 ( Jae Hee Ahn ),장원진 ( Won Gin Chang ),손장욱 ( Jang Wook Sohn ),김민자 ( Min Ja Kim ) 대한내과학회 2012 대한내과학회지 Vol.82 No.1

저자들은 rifampin에 과민 반응이 있는 환자가 rifampin에 다시 노출된 후, 아나필락시스 및 횡문근 융해증, 급성 신부전, 파종성 혈관내응고증후군이 병별하여 결국 사망에 이르렀던 예를 경험하여 문헌고찰과 함께 보고하는 바이다. A 44-year-old patient who had been diagnosed with tuberculous Lymphadenopathy came to our hospital with a rash. He began to take antituberculous medications, but the next day, a rash appeared and persisted for one week. When he came to the hospital, he had already stopped the medication by his own decision. We stopped all drugs and reintroduced one drug at a time. After re-administration of rifampin, anaphylactic shock and subsequent acute renal failure and rhabdomyolysis occurred. Intensive care was performed, but the patient died 60 h after the first hypersensitive reaction that occurred due to rifampin. Anaphylaxis and subsequent rhabdomyolysis induced by rifampin is an extremely rare event. It is necessary to initially prescribe low dose rifampin in cases of re-administration. (Korean J Med 2012;82:115-118)