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치어기 넙치 사료내 ${\beta}-1,3$ 글루칸의 첨가가 성장 및 비특이적 면역반응에 미치는 영향
김영철,김강웅,이승형,박건준,강용진,배승철,Kim, Young-Chul,Kim, Kang-Woong,Lee, Seung-Hyung,Park, Gun-Jun,Okorie, Okorie Eme,Kang, Yong-Jin,Bai, Sung-Chul C. 한국양식학회 2006 韓國養殖學會誌 Vol.19 No.4
본 실험은 치어기 넙치에 잇어서 ${\beta}-1,3$ 글루칸을 사료내 첨가시 성장, 비특이적 면역반응 및 질병저항성에 미치는 영향을 조사하기 위하여 사료내 ${\beta}-1,3$ 글루칸을 수준별 첨가하여 실시였다. 실험어는 평균무게 3.2 g인 넙치 치어를 사용하였으며, 기초사료에 ${\beta}-1,3$ 글루칸을 대조구, ${\beta}-1,3$ 글루칸 0.01, 0.025%, 0.05% 및 0.1%를 각각 첨가하여 총 5개 실험구로 3반복배치하여 6주간 실시하였다. 총 6주간의 성장 실험결과, 면역증강물질인 ${\beta}-1,3$ 글루칸의 첨가에 따르는 사료효율과 단백질전환효율에 있어서 ${\beta}-1,3$ 글루칸 0.1%를 공급한 사료구가 대조구와 다른처리구에 비하여 유의하게 높은 값을 나타냈다(P<0.05). 증체율과 일간성장율에 있어서는 ${\beta}-1,3$ 글루칸 0.1%를 공급한 사료구가 대조구, ${\beta}-1,3$ 글루칸 0.01%, 0.025%를 첨가한 구보다 유의하게 높은 값을 나타내었지만 ${\beta}-1,3$ 글루칸 0.05%구와는 유의한 차이가 없었다. 비만도에 있어서는 ${\beta}-1,3$ 글루칸 0.05%와 0.1%를 첨가한 구가 대조구와 첨가구보다는 유의적으로 높았다. 헤마토크리트치는 ${\beta}-1,3$ 글루칸 0.05%와 0.1%첨가한 실험구가 대조구와 ${\beta}-1,3$ 글루칸을 0.01%와 0.025%를 첨가한 실험구에 비하여 유의하게 높은 값을 나타내었다(P<0.05). 혈청내 GOT에 있어서 ${\beta}-1,3$ 글루칸 0.05%와 0.1%를 첨가한 실험구가 대조구, ${\beta}-1,3$ 글루칸 0.01%와 0.025%를 첨가한 실험구보다 유의하게 낮은 값을 나타내었다(P<0.05). 비특이적 면역반응 결과에 있어서는 ${\beta}-1,3$ 글루칸을 0.05%와 0.1%를 첨가한 실험구가 혈청의 lysozyme 활성 및 두신 phagocyte의 chemiluminescent(CL) 반응에서 대조구, ${\beta}-1,3$ 글루칸 0.01%와 0.025%를 첨가한 실험구보다 유의하게 높은 값을 나타내었으나, 보체대체활성의 경로에 있어서는 전실험구간의 유의한 차이를 보이지 않았다. 공격 실험 결과에서는 ${\beta}-1,3$ 글루칸을 첨가한 실험구가 대조구에 비하여 초기폐사율이 낮음을 확인할수 있었으며, 상기 결과를 토대로, 넙치 치어의 경우 ${\beta}-1,3$ 글루칸을 0.05% 이상 0.1% 미만을 사료에 첨가하는 것이 성장, 사료효율 증진, 항산화능 및 질병저항성에 가장 좋은 효과를 나타낼 수 있을 것을 사료된다. This study was conducted to investigate the effects of dietary supplementation of ${\beta}-1,3$ glucan on growth and immune responses in juvenile olive flounder, Paralichthys olivaceus fed the white fish meal based diets for 6 weeks. Five experimental diets supplemented with ${\beta}-1,3$ glucan at 0, 0.01, 0.025, 0.05, 0.1 % (Control, $G_{0.01},\;G_{0.025},\;G_{0.05}\;and\;G_{0.1}$, respectively) of diet on a dry-matter basis. Five experimental diets were formulated to be isonitrogenous and isocaloric to contain 50.0% crude protein and 16.7 kJ available energy $g^{-1}$. Fish averaging $3.2{\pm}0.1\;g\;(mean{\pm}SD)$ were randomly distributed in each aquarium as triplicate groups of 15 fish. Weight gain (WG, %), specific growth rate (SGR, %), and feed efficiency (FE, %) of fish fed $G_{0.1}$ diet were found significantly higher than those of fish fed Control, $G_{0.01},\;G_{0.025}\;and\;G_{0.05}$ diets (P<0.05). However, there was no significant difference among the fish fed control, $G_{0.01},\;G_{0.025}$. Chemiluminescent responses (CL) of fish fed $G_{0.1}$ diet were significantly higher than those of fish fed the other diets. Serum lysozyme activities of fish fed $G_{0.05}$ and $G_{0.1}$ diets were higher than those of fish fed control, $G_{0.025}$ and $G_{0.05}$ diets. Fish fed $G_{0.1}$ diet showed a significantly lower cumulative mortality than did fish fed control diet throughout the challenge test (P<0.05). These results suggested that based on growth rate, feed efficiency, non-specific immunity and protection against microbial infections the optimum dietary ${\beta}-1,3$ gulcan could be greater than 0.05% but less than 1.0% in juvenile olive flounder, Paralichthys oilvaceus.
치어기 넙치(Paralichthys olivaceus)에 있어서 어분 대체원으로써 탈피대두박을 이용하여 생산한 오징어 간분의 평가
김영철 ( Young Chul Kim ),배승수 ( Sung Su Bae ),이준호 ( Jun Ho Lee ),박건현 ( Gun Hyun Park ),이정열 ( Jeong Yeol Lee ),배승철 ( Sung Chul C. Bai ) 한국수산학회 2009 한국수산과학회지 Vol.42 No.3
This study was conducted to determine the proper inclusion levels of squid liver powder (SLP) and dehulled soybean meal (DHSM) as a fish meal (FM) replacement in the diets for olive flounders. All the experimental diets were formulated to be isonitrogenous (50% crude protein, CP) and isocaloric (17.1 kJ energy g-1 diet). Four diet were formulation of FM with SLP (DHSM) were tested at 0, 25, 50, 75% (SLP(DHSM)0, SLP(DHSM)25, SLP(DHSM)50 and SLP(DHSM)75, respectively). Triplicate groups of 12 fish with an average body weight of 5.56±0.1g(mean±S.D.) were fed one of three experimental diets for 7 weeks. Weight gain (WG) and the specific growth rate(SGR) of fish fed SLP(DHSM)0 and SLP(DHSM)25 diets were significantly higher than those of fish fed SLP(DHSM)50 and SLP(DHSM)75 diets (P<0.05). Also, WG and SGR of fish fed SLP(DHSM)50 had significantly higher WG and SGR than that of fish fed SLP(DHSM)75 (P<0.05). The feed efficiency (FE) and protein efficiency ratio (PER) of fish fed SLP(DHSM)0 and SLP(DHSM)25 were significantly higher than those fed SLP(DHSM)50 and SLP(DHSM)75 (P<0.05). The whole-body crude lipid content of fish SLP(DHSM)75 was significantly higher than that of fish fed SLP(DHSM)50 (P<0.05). However, there were no significant differences in whole-body moisture, crude protein and crude ash of fish fed all diets. Based on these growth performance results, the SLP(DHSM) combination replace up to 25% FM protein by the ANOVA test in juvenile olive flounder diets.
김영철(Young-Chul Kim),Glenn C. Loury 한국재정학회 2016 한국재정학회 학술대회 논문집 Vol.2016 No.-
We develop a theoretical model explaining how the problem of poor labor market outcomes for ex-convicts might be alleviated by a government intervention. While employers wish to avoid associating with those who will end up returning to crime, they cannot be certain from the available information which convicts will reoffend and which will not. We illustrate that, notwithstanding this informational asymmetry, a government can nevertheless design a costly, yet net socially beneficial program through which some ex-convicts can credibly convey their good intentions to employers. Such a “rebranding” program can help more ex-convicts find legitimate work, with fewer electing to return to crime than would otherwise have been the case.
치어기 넙치 사료내 Seleno-yeast 수준에 따른 조직학적 변화
배승철 ( Sungchul C. Bai ),김영철 ( Young Chul Kim ),이준호 ( Jun Ho Lee ),김재원 ( Jae Won Kim ) 한국어병학회 2010 한국어병학회지 Vol.23 No.1
본 실험은 치어기 넙치 사료 내 셀레노이스트 첨가에 따른 영향을 평가하기 위하여 조직학적 반응을 살펴보았다. 사료 내 셀레늄은 각각 0ppm, 1ppm, 3ppm 및 5ppm의 총 4개 실험구로 설정하였으나 실험사료 분석을 통하여 사료내 셀레늄의 함량은 각각 0.56, 1.07, 2.86 및 4.56mg Se/kg으로 나타났다. (Se0.56, Se1.07, Se2.86, 및 Se4.56). Se1.07 실험구의 신장에서 사구체의 혈구세포가 점진적인 팽창을 보여주고, 일부 세뇨관의 상피세포들의 파열도 나타나기 시작하였으며 대식세포도 점차적으로 커지는 것을 알 수 있었다. Se0.56 실험구의 간에서 정상적인 형태를 갖추고 있다. 농도가 증가될수록 모세 혈관 내 혈구의 팽창, 췌장 효소원 과립의 감소, 간세포의 팽창이 점진적으로 진행되는 볼 수 있었다. 그리고 Se1.07 실험구에서 일부 비정상적인 새판을 가지는 것으로 나타났으나 Se0.56 실험구와 크게 차이가 없는 것으로 관찰되었다. 이상의 세 기관의 조직학적 연구에서 치어기 넙치 사료내 첨가제로서 셀레노이스트의 적정 첨가량은 1.07mg/kg이하 수준이 적당한 것으로 사료된다. This study was conducted to investigate the effects of dietary seleno-yeast on histological response in juvenile olive flounder Paralichthys olivaceus. Fish averaging 4.0±0.1g (mean±SD) were fed one of the four semi-purified diets containing 0.56, 1.07, 2.86 and 4.56mg Selenoyeast/kg diet (Se0.56, Se1.07, Se2.86 and Se4.56, respectively) in triplicates for 12weeks. Swelling of blood cell in glomerulus, the rupture of some epithelial cell in the renal tubules and enlarged macrophage were observed in the Se1.07group. The hepatopancreas had hepatic cell, capillary and zymogen in the pancreas and was normal in the Se0.56 group. Swelling of hepatocyte gradually decreased with increase in selenoyeast supplementation. The gill lamellae showed partial abnormal condition (terminal clubbing) in the Se0.56group, but there were little differences between these and other treatments. These results indicated that the optimum dietary supplementation level of selenoyeast in juvenile olive flounder, Paralichthys olivaceus, could be less than 1.07mg selenoyeast/kg diet based on histological responses of the fish.
인공습지와 기계적 처리요소를 연계한 마을하수 처리기술의 개발
이치타오(Yi, Qitao),권태영(Kwon, Tae-Young),박동소(Park, Tong-So),김영철(Kim, Y.C.) 한국산학기술학회 2009 한국산학기술학회 학술대회 Vol.- No.-
기계적인 요소와 자연적인 요소를 연계한 마을하수처리 실증플랜트의 가동후 공정별 수질분석 및 자료수집개시: 2008년 9월20일에 착수하여 1주에 1회 간격으로 현재까지 공정별 26회의 현장방문과 수질조사를 실시하였다. 질산화 전환율은 70∼80%로 훌륭하나 탈질은 탄소원 부족으로 저조하였다. 그 이유는 유기물질은 전처리 단계인 바이오필터에서 대부분 제거되었기 때문으로 참여기업과 협의하여 바이오 필터 체류시간 감축방안 수립하여 운영한 결과 탈질효율을 향상시킬 수 있었다. 유기물질 제거효율은 상시적으로 90% 이상의 제거효율 달성할 수 있었다.
폐암환자에서 발생한 피하매몰 중심정맥포트 골절 및 색전증 2예
주진영 ( Jin Yung Ju ),조재영 ( Jae Yeong Cho ),임정환 ( Jung Hwan Lim ),조계중 ( Gye Jung Cho ),채동렬 ( Dong Ryeol Chae ),오인재 ( In Jae Oh ),김규식 ( Kyu Sik Kim ),김유일 ( Yu Il Kim ),임성철 ( Sung Chul Lim ),김영철 ( Young C 대한결핵 및 호흡기학회 2007 Tuberculosis and Respiratory Diseases Vol.63 No.5
Totally implanted central venous access devices for chemotherapy (chemoport) are being used increasingly in lung cancer patients. Vascular catheters are associated with various complications including infection, thrombosis as well as spontaneous fractures and embolization of the catheter, which is known as ``pinch-off syndrome``. ``Pinch-off syndrome`` refers to the compression of a subclavian central venous catheter between the clavicle and first rib resulting in an intermittent or permanent obstruction, which can lead to tears, transection, or embolization. We report two cases of fractured and embolized implanted subclavian venous catheters in which the fragments were removed percutaneously. A 62-year-old man presented with back pain with a duration of a few weeks. The chest radiograph revealed complete transsection and embolization of the catheter into the right atrium. In addition, a 47-year-old woman with a chemoport had a grade 3 pinch-off sign in a chest radiograph demonstrating complete transsection and embolization of the catheter into the pulmonary artery. Both cases were managed by retrieving the embolized distal fragment percutaneously and removing the proximal section of the catheter. (Tuberc Respir Dis 2007;63:449-453)