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      • KCI등재

        케톤생성 식이요법 후 급성신부전 및 단백열량부족증 소견을 보인 영아성 경축 1례

        김영명,김태홍,정진아,황규근,Kim, Young-Myoung,Kim, Tae-Hong,Jung, Jin-A,Hwang, Kyu-Geun 대한소아청소년과학회 2003 Clinical and Experimental Pediatrics (CEP) Vol.46 No.11

        저자들은 영아성 경축 환아에서 케톤생성 식이요법 중 단백열량부족증(Kwashiorkor)을 포함한 중증의 탈수, 급성신부전과 흡인성 폐렴을 동반한 영아성 경축 1례를 경험하여 문헌 고찰과 함께 보고하여 케톤생성 식이요법시 참고를 하고자 한다. The ketogenic diet is a high-fat, low-protein, low-carbohydrate diet developed in the 1920s for the treatment of difficult-to-control seizures. Despite advances in both the pharmacotherapy and the surgery of epilepsy, many children continue to have difficult-to-control seizures. In this situation, a ketogenic diet should be considered as an alternative therapy. However, less attention has been paid to associated adverse events in the ketogenic diet. We report a case of infantile spasm associated with acute renal failure, lipoid pneumonitis and kwashiorkor after ketogenic diet. A better understanding of this adverse event profile will allow the pediatric neurologist to have a true informed consent discussion with the care giver when considering initiation of the ketogenic diet.

      • KCI등재

        미래사회의 고객니즈 분석을 통한 시나리오 기반의 미래 기술예측 방법론

        김영명(Young Myoung Kim),김민관(Min Kwan Kim),이준석(Jun suk Lee),한창희(Chang Hee Han) 한국경영과학회 2011 經營 科學 Vol.28 No.3

        Recently, the level of uncertainty in R&D investment for an enterprise has increased due to technological development and industrial changes. Accordingly it is necessary for an enterprise to forecast the future or foresight the future technologies. But, the fact that the methodology used in predicting future technology is suitable for large project makes enterprise difficult to forecast the future technologies or trends. Thus, this study seeks for available methodology for future technology foresight from enterprise standpoint. The methodology proposed in this research is based on the scenario model, especially focused on the customer needs and future society change.

      • KCI등재

        대황(Eisenia bicyclis)으로부터 Laminaran의 정제 및 화학적 특성

        김영명(Young-Myoung Kim),최용석(Yong-Seok Choi),박종혁(Jong-Hyuk Park) 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.1

        국내 울릉도 연안에서 자생하는 대황에서 라미나란을 분리, 정제 분획하여 구조적 특성을 비교하였다. 분쇄한 대황을 0.09 N HCl로 추출한 조 라미나란과 이를 CPC로 정제한 부분 정제 라미나란의 수율은 각각 14.5%, 6.5%였으며, 그 화학적 조성을 비교해 보면, 총당의 함량이 68.2%에서 74.7%로 증가하였고, 단백질의 함량(8.4%→3.8%) 및 황산기의 함량(7.6%→3.2%)로 감소하였으며, 주요 구성당인 glucose의 함량이 55.0%에서 83.3%로 증가하여 CPC를 사용하여 라미나란을 간단히 정제할 수 있었다. 라미나란의 분자량 및 당구조 분석을 위하여 부분정제 라미나란을 Sephacryl S-300 HR 칼럼으로 정제하였으며, 이 정제물의 평균 분자량은 12,500 dalton이었다. 그리고 총당의 함량이 89.9%, 단백질 함량은 1.1%, 그리고 황산기 함량 0.8%이었으며, 주요 구성당인 glucose의 함량이 98.3%였다. 그리고 FT-IR 분석 결과 glucose는 대부분 β-결합(888 ㎝-¹)의 형태로 존재하는 것을 확인하였다. 그리고 ¹³C NMR 분석 및 methylation 분석을 해본 결과 라미나란은 주로 β-1,3 결합에 β-1,6 분지를 갖는 glucan임을 확인하였다. Laminarans with different purity were prepared from Eisenia bicyclis and their structures were characterized. Crude laminaran was successively extracted two times at room temperature for 2 hr with 0.09 N HCl, and partially purified laminaran was isolated using cetylpyridinium chloride (CPC). Crude laminaran accounted for 14.5% of the dry seaweed weight and contained 8.4% protein, 7.6% sulfate and 68.2% polysaccharide. Partially purified laminaran accounted for 6.5% of the dry algal weight and composed of 3.8% protein, 3.2% sulfate and 74.7% total sugar, which is mainly composed of glucose (83.3%), indicating that partially purified laminaran was more purified polysaccharide than crude laminaran. Purified laminaran was fractionated into one fractions by Sephacryl S-300 HR column chromatography and this fraction was analysed by FT-IR, ¹³C NMR, methylation and gel filtration chromatography. Purified laminaran showed β-configuration (¹³C: 103.0 ppm, FT-IR: 888 ㎝-¹) in the anomerization of the glycosidic linkages and was (1→3), (1→6) linked β-glucan. The average molecular weight of purified laminaran was 12,600 dalton.

      • SCOPUSKCI등재

        톳유래의 무기성분강화염이 본태성 고혈압쥐와 정상쥐의 혈압과 미네랄대사에 미치는 영향

        김영명(Young Myoung Kim),변지영(Jee-Young Byun),한찬규(Chan-Kyu Han),성기승(Ki-Seung Sung),남궁배(Bae NamGung) 한국식품과학회 2009 한국식품과학회지 Vol.41 No.2

        본 연구는 톳유래의 무기성분강화염이 혈압과 무기질 대사에 미치는 영향을 검토하기 위하여 수행하였다. 실험처리는 고·저염식군(Hizikia mineral salt)과 대조군(정제염)의 세가지 처리군으로 하였고, 실험동물인 본태성 고혈압쥐(SHR/NCrj)와 정상쥐(WKY/NCrj)에 음용수의 형태로 식염을 급여하였다. SHR에서는 시험 6주째 수축기혈압(SBP)이 C군보다 고·저염식군(A, B)이 각각 17, 24 mmHg 낮았고, 기준혈압(RBP)대비 시험 6주째 혈압의 상승율은 A, B, C군에서 각각 12, 4, 21%로 B군이 가장 낮았다. WKY의 경우 시험 6주째 SBP는 A군과 C군에서 각각 165, 164 mmHg인 반면, B군은 148 mmHg로 훨씬 낮았다. RBP 대비 시험 6주째 혈압의 상승율은 A, B, C군에서 각각 17, 7, 19%로 B군이 가장 낮았다. 소변과 분변 중의 미네랄은 SHR/WKY 종에서 무기성분강화염군이 정제염군보다 Na<SUP>+</SUP> 함량은 유의하게 낮았지만 K<SUP>+</SUP> 함량은 무기성분강화염군이 정제염군보다 유의하게 또는 대체로 높았다. 소변과 분변 중 미네랄함량은 다소간 차이가 있었지만 대변보다 소변으로 더 많이 배설된 것으로 나타났다. 간장의 경우 SHR은 K<SUP>+</SUP>을 제외한 Na<SUP>+</SUP>, Ca<SUP>++</SUP> 및 Mg<SUP>++</SUP> 함량은 무기성분강화염군보다 대조군이 통계적으로 높았다(p<0.05). WKY에서 Na<SUP>+</SUP> 함량은 고염식군(A)이 가장 높았고, 신장에서 SHR의 Na<SUP>+</SUP> 함량은 정제염군이 무기성분강화염군보다 높았지만 WKY에서는 오히려 A군과 B군이 대조군보다 높았고, K<SUP>+</SUP> 함량은 저염식군(B)이 가장 높았다(p<0.05). 이상의 결과에서 톳유래의 저염식은 Na<SUP>+</SUP> 함량은 낮추고 K<SUP>+</SUP> 함량은 높이는 등의 체내 미네랄 대사에 긍정적인 영향을 미치기 때문에 혈압상승 억제작용이 있는 것으로 사료되었다. This study was conducted to evaluate the effects of the salts fortified with Hizikia component on blood pressure and mineral composition in spontaneously hypertensive rats (SHR/NCrj) and normotensive rats (WKY/NCrj). The two species rats were assigned to three groups and were fed with drinking water to which Hizikia salts were added for 6 weeks. The final blood pressures (BP) among groups of SHR were increased to 12, 4, and 21%, respectively. In terms of urine and fecal minerals, the Na<SUP>+</SUP> contents in two species were significantly higher in the control than in the salt groups, and vice versa with regard to the K<SUP>+</SUP> contents. The amount of excretion mineral was higher in urine than in feces. The Na<SUP>+</SUP>, Ca<SUP>++</SUP> and Mg<SUP>++</SUP> contents of the liver in SHR were higher in the control than in the salt groups (p<0.05). The Na<SUP>+</SUP> content of the kidney in SHR was higher in the control than in the salt groups, but the content was shown an opposite trend in WKY. The K+ contents were higher in the low salt group (p<0.05). These results may indicate that the salts fortified with the Hizikia component may be useful in lowering systolic blood pressure owing to the maintenance of positive mineral metabolism.

      • KCI등재

        R&D 프로젝트 성과의 경제적 가치 측정 모델 연구

        김영명 ( Young Myoung Kim ),성한규 ( Hank Yu Sung ) 기술경영경제학회 2013 Journal of Technology Innovation Vol.21 No.1

        본 연구의 목적은 연구개발(R&D) 프로젝트의 성과를 재무적 가치로 측정하기 위한 모델을 제안하는 것이다. 이를 위해 선행 연구를 통해 연구개발 프로젝트 성과를 측정할 수 있는 지표를 추출하고, 그 측정 방법을 제시하였다. R&D 성과를 재무적 가치로 환산하려는 일부 시도가 있었으나 전문가 평가, 예상 매출액, 미래시장 점유율, 할인율, 순현재가치, 실물옵션 접근법 등 주관적 의견과 과도한 예측으로 측정결과에 대한 의문이 제기되었다. 이러한 문제점을 보완하고 다양한 각도에서 재무적 가치로 평가가 가능한 모델을 제안하고자 한다. 개발된 모델을 국내 IT 기업의 실제 사례를 통하여 검증을 실시하여 신뢰성을 높였기 때문에 추후 기업의 R&D 프로젝트에 대한 경제적 평가에 새로운 전기를 마련할 수 있을것으로 기대된다. The aim for this study is to suggest a practical model to measure the financial values of the achievements from corporate research and development(R&D) projects. Performance indicators for R&D projects were identified from the extensive literature reviews and the evaluation methods to convert them into financial values were proposed to overcome the problems of excessive predictions and subjective expert assessments in existing methods. The proposed model was applied to R&D projects of an IT company in Korea for its validity test. The model is expected to be a turning point in economic evaluation of corporate R&D projects in general due to its practical and reasonable scheme.

      • 한ㆍ중ㆍ일 체육전공 대학생의 스포츠 상해에 관한 임상적 고찰

        김영명(Kim Young-Myoung),김종동(Kim Jong-Dong) 동아대학교 스포츠과학연구소 2005 스포츠科學硏究論文集 Vol.23 No.-

          This study analyzed the status of sports injury occurring in the university students of Korea, China and Japan who major in athletics. The survey questionnaire was collected from 1,017 students majoring in athletics at 4-year universities located in Busan, Korea and 478 students majoring in athletics at 4-year universities in Kyushu, Japan. Also 856 university students in athletics-related majors in Beijing and Shanghai, China, answered the questionnaire. The research results are as follows: The rate of experiencing sports injury and handicap before entering university was found to be the lowest in Korean students. On the other hand, the rate of healing after sports injury and handicap was the highest in China Chinese students experienced less sports injuries and handicap than Japanese students. This shows that China has better environment to treat and care sports injuries. After entering university, Japanese students and Chinese students experienced sports injuries and handicap in similar frequencies(67% for Japan and 61% for China). Korean students had lower rate of 51% than their counterparts in China and Japan. Compared to before and after entering university, students of .all three countries had less sports injuries and handicap experiences after they entered university than before they entered university. Sports injuries and handicap rates by the month were found higher between March and May in Korea and between April and October in China and Japan. This result implies that sports injuries have something to do with the school opening seasons and sports season of each country as well as the cold weather.<BR>  The body parts which had higher rates of sports injuries were knee joints, ankle joints and legs in all three countries. Also students suffered back pain a lot (especially in case of women regardless of country). The rate of sports injuries increased as students went into a higher grade. Therefore a regular exercise program to strengthen the body parts susceptible to injury and an aftercare treatment following games are necessary. In terms of experiencing of handicap at the time of exercise and everyday life, Japanese students answered more positively than the students of Korea and China. However, Korean and Chinese students answered that they experienced more handicap at the time of playing games than their Japanese counterparts. First aid was given best in Japan, and the rate of students who answered they knew how to give first aid was highest in Chinese students. Comparison of athletics-majors and non-athletics majors showed that the group of students majoring in athletics had higher rates of first aid experience than non-athletics majors in all three countries. Japanese students were found to be more active in preventing their injuries than Korean or Chinese students. Therefore, the group of athletics-majoring students in all three countries were found to be more active in taking care of their body and preventing injuries than non-athletics majors.

      • KCI등재
      • KCI등재

        ICT 연구개발 프로젝트 발굴을 위한 창의적 방법론

        김영명(Young-Myoung Kim),노윤정(Younjung Ro) 한국IT서비스학회 2012 한국IT서비스학회지 Vol.11 No.2

        The rapid evolution of ICT industry brings not only new services or products but also changes from common individual life to whole human society. Coping with these situations and survival, companies cannot help regarding R&D as the most important thing. So, discovering R&D projects which are suitable for the alternation is a big issue for many companies. To resolve the issue, KT has adopted Innovative Management Methodology developed by Strategos, which is co-founded by Gary Harmel. This paper describes this Innovative Management Methodology tailored to KT R&D. The methodology consists of five phases:focusing discovery, discovery, ideas/domains, domain elaboration & aiming point and R&D project proposal. Also, it shows some interim findings that came from the Innovative Management Process. Finally, the future plan for elaborating the methodology itself and generating new R&D projects is suggested.

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