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RISS 인기검색어
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- 저자 : 김영건 ( Young Kun Kim ) (검색결과 164 건)
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김선영(Sun Young Kim),김진희(Jin Hee Kim),이경태(Kyung Tae Lee),이승민(Seung Min Lee),김석현(Seok Hyun Kim),이병석(Byung Seok Lee),김남재(Nam Jae Kim),정현용(Heon Young Jeong),이헌영(Heon Young Lee),김영건(Young Kun Kim) 대한내과학회 1999 대한내과학회지 Vol.56 No.5
N/A Objective : Eradication of H. pylori not only results in ulcer healing, but reduces recurrences essentially curing peptic ulcer disease. The purpose of this study was to evaluate the eradication rate of H. pylori and side effects with regard to three drug regimens. Methods : 96 patients were included and divided into three groups: 14 patients(group 1: OA) received omeprazole(20 mg b.i.d.) and amoxicillin(1.0 gm b.i.d.) for 14 days ; 12 patients (group 2: BAM) received colloidal bismuth subcitrate(CBS)(120 mg b.i.d.), amoxicillin(500 mg q.i.d.) and metronidazole(250 mg q.i.d.) for 14 days. ; 70 patients(group 3: OAC) received omeprazole(20 mg b.i.d.), amoxicillin(500 mg q.i.d.) and clarithromycin(250 mg q.i.d.) for 10 days. The diagnosis of the status of H. pylori was made by histology or culture or rapid urease test(CLO test). Results : 1) The eradication rate of H. pylori was higher group 2(91.7%) and group 3(91.4%) than group 1(57.1%). 2) The total failure rate regardless of the regimens (n=96) was 13.5%(13 patients). 10 patients whose treatment failed were randomly assigned to receive retreatment with the alternative regimen of BAM or OAC. In retreatment group(n=10), the eradication rate of H. pylori infection was achieved in 100 %. 3) The side effects were oral burning sensation, odynophagia, nausea, epigastric pain, diarrhea, constipation, gas bloating. The side effects were negligible. Conclusions : 10-day therapy with omeprazole, amoxicillin and clarithromycin(OAC) achieved eradication rate of 91.4 %. The side effects were few and negligible. 10-day therapy with OAC was a safe and very effective regimen for the eradication of H. pylori infection.
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Ranitidine 의 소화성궤양치료효과에 대한 임상적연구
김영건(Young Kun Kim),윤성열(Sung Yeul Yoon),정현용(Hyeon Yong Jeong),정선묵(Seon Muk Jeong) 대한소화기학회 1983 대한소화기학회지 Vol.15 No.2
N/A This study was performed to assess the clinical therapeutic effectiveness of anti-histamine agent, ranitidine. The drug was given in the dose of 150mg twice a day to 12 cases of gastric ulcer and 11 cases of duodenal ulcer. Initial diagnosis and follow up observation after 4 weeks, 6 weeks and 8 weeks of treatment were made by the upper G-I endoscopy. The results observed are as followings. 1) The male to female ratio of the subject was about 20:3 and the most prevalent age group was the sixth decade of the life in both the gastric and duodenal ulcer groups. 2) The location of gastric ulcer were 7 cases in body and 5 cases in angle of the stomach and duodenal ulcer were 7 cases in bulb and 4 cases in pyloric area. 3) As for the subjective symptoms, epigastric pain, heart-burning sensation, hunger pain, abdominal discomfort, dyspepsia were experienced, and were relieved after 1 week of treatment in 60 80%, and were completely relieved after 4 weeks of treatment in all cases respecti vely. 4) The cumulative rates of complete healing of the gastric ulcer (12 cases) were 75% (9 cases) after 4 week, 92% (11 cases) after 6weeks, 100%(12 cases) after 8 weeks of treatment, and those of the duodenal ulcer (11 cases) were 91%(10 cases) after 4 weeks, 100%(11 cases) after 6 weeks of treatment. 5) The untoward side effect were not found. In conclusion ranitidine appears to be effective and safe for the treatment of patients with peptic ulcer disease.
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김영건(Young Kun Kim),이복희(Bok Hee Lee),정선묵(Seon Muk Jeong),정현용(Hyun Yong Jeong),김연길(Yun Keel Kim) 대한소화기학회 1984 대한소화기학회지 Vol.16 No.2
N/A A clinical analysis was performed in 408 patients with peptic ulcer among the various upper gastrointestinal diseases(2108 cases), who were diagnosed gastroduodenoscope at the endoscopic room of Chung Nam National University Hospital during period from January 1980 to August 1984. The results were as',follows: I) Of the total 2108 cases, the main diseases were gastritis(28.5%), gastric cancer(195 benign gastric ulcer(11.5%), etc, in order of frequency. 2) The symptoms of peptic ulcer were epigastric pain or discomfort(83.5%), melena or hematemesis(39.4%), indigestion, etc. 3) Of the 408 cases with peptic ulcer, 239 cases(58%) were gastric ulcer, 144 cases(35%) were duodenal ulcer and others were gastroduodenal combined ulcer. 4) Of the 408 cases with peptic ulcer, 339 cases (83.1%) were male and 68 cases(16.9%) were female. The male to female ratio was 5:1 and the highest number was in the 3th decade (26.2%). Gastric ulcer was distributed most commonly in the 6th decade(32.6%) and had high male to female ratio(6:1). Duodenal ulcer was been relatively younger age of the 4th decade(25%) and 5th decade(24%), had low male to female ratio(3.5:1). 5) In the annual distr ibution of peptic ulcer from to 1984, gastric ulcer was 29.9%, 69.8%, 62.0%, 54.1%, 51.1%, respectively and duodenal ulcer was 28.6%, 27.9%, 33.8%, 37.8% and 40%. And there was evidence of increasing tendency in duodenal ulcer. 6) The most common prevalent site of gastric ulcer in all age was gastric angle. The more old age, the upper stomach was involved. The most favorable site of duodenal ulcer was bulb (81.2%) and pyloric canal(17.4%). 7) The most frequent size of gastric ulcer(34.6%) was from l.0 cm to 1.9 cm. And that of duodenal ulcer was from pinhead to 0. 4cm(50.2%). 8) Among the 408 cases who has been confirmed peptic ulcer by gastroscopy, 219 cases have been taken UGI examination concomitantly. The concordance rate of gastric ulcer, duodenal ulcer svas 70%and 76.9%, respectively.
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김영건(Young Kun Kim),이복희(Bok Hee Lee),박헌진(Hun Jin Park),이헌영(Heon Young Lee),안정기(Jeong Ki Ahn),강원권(Won Kwon Dang) 대한소화기학회 1989 대한소화기학회지 Vol.21 No.1
N/A The clinical, laboratory and pathological features were evaluated in 44 patients with fatty liver, those were proved by nedle biopsy. The following results were obtained. 1) The mean age of the patients was 40.2 ± 11.8 years old, and the most prevalent age group was 4th decade (40.9%). The male and female ratio was 3.4:l. 2) Suspected etiologies were obestity (61.4%), alcohol (18.2%), crytogenic (13.6%), Diabetes Mellitus (6.8%), and prednisolon (2.3%), in order of frequency. 3) Clinical symptoms were asymptomatic (50%), fatigue and/or weakness (43%) and anorexia (16 %) etc. 4) Degrees of fatty infiltration on biopsy specimens revealed mild (18.2%) moderate (45.5%) and severe (36.4%). 5) Degrees of ultrasonographic findings (20 cases) resemble those degree of biopsy findings and positive rate was 80%. 6) Liver scan showed mottlings in 44% of patients and 28% of patients had no abnormal findings. 7) HBsAb positive cases were 61.4%, and no HBV markers found in 31.8% of the patients. 8) Diagnoses without liver biopsy were NANB hepatitis about half of the patients and only 20% of cases were suspected as fatty liver. 9) At the time of diagnosis, hypertriglyceridemia revealed at rate of 75% (30/40 cases) and the differences of the levels of serum TG, ALT and AST according to the degrees of fatty infiltration were not presented significantly. 10) The differences of the TG, ALT and AST levels between before and after treatment were noted significantly. 11) The significant relationships between degrees of fatty liver and degrees of obesity were observed (Grade I and II: p<0.05, I and III: p<0.01).
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위내시경으로 진단된 소화성 궤양환자 1501명에 대한 임상적 관찰
김영건(Young Kun Kim),이복희(Bok Hee Lee),김성철(Sung Chul Kim),박헌진(Hun Jin Park),안정기(Jeong Ki Ahn),이헌영(Houn Young Lee) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.3
N/A The epidemiology and clinical aspect of peptic ulcer is ever-changing along with changes in environment. Therefore, we had a clinical analysis in 1501 patients, who were diagnosed as peptic ulcer with gastroscopy in Chungnam National University Hospital from January 1984 to June 1988. The results were as follows: 1) Of the total 8912 cases of endoscopy, the numbers of patient with gastric ulcer were 784(8.8%), with duodenal ulcer, 591(6.6%) and with combined ulcer, 126(1.4%) 2) The mean age of patients with gastric ulcer was 50.9+14.9, and that with duodenal ulcer was 41.76+13.8. 3) The ratio of males to females was 3.7: 1 in gastric ulcer group and 2.4: 1 in duodenal ulcer group. 4) The most common stympom was epiagastric pain, 48.3% of gastric ulcer patients and 47.2% of duodenal ulcer patients, And the patients with hematemesis and/or melena were 19.5% of gastric ulcer patients and 12.9% of duodenal ulcer patients 5) During the period 1984-1988, the annual proportion of gastric ulcer were 58.8%, 51.4%, 53.3%, 50%, and 50.7%. And that of duodenal ulcer were 36.5%, 39.4%, 38.2%, 40.5%, and 41.1%. 6) The patients with multiple ulcers were 26.5% of gastric ulcer group and 15.7% of duodenal ulcer group. 7) The patients of 78.1% of total peptic ulcer was in active stage, 11% in healing stage, and 10.9% in scarring stage. 8) In 30.8% of gastric ulcers, the size of ulcer was within 1.0 to 1.4 cm and in 31.6% of duodenal ulcers the size of ulcer was less than 0.4 cm. 9) The most common site of gastric ulcer was angle of stomach (42.7%), and that of duodenal ulcer was bulb (98.6%). 10) The proportion of patients with combined ulcer of stomach and duodenum was 8.3% of total patients and that of channel ulcer was 3.1%.
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한국인소화액에 관한 면역학적 연구 - 제 1 편 정상인 위액의 Immunoglobulin
김영건 ( Young Kun Kim ) 대한내과학회 1970 대한내과학회지 Vol.13 No.6
It is now well established that immunoglobulins found in external secretions of man differ both in molecular structure and relative concentrations from those in serum. In colstrum, parotid fluid, and nasal secretions, IgA is the predominate major class of
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김영건(Young Kun Kim),이형호(Hyung Ho Lee),백남종(Nam Jong Baeg),장병환(Byeng Hwan Jang),김성철(Sung Chul Kim),박헌진(Hun Jin Park) 대한소화기학회 1987 대한소화기학회지 Vol.19 No.2
Stomach cancer is the most common malignant neoplasm in Korea, and the 5-year survival rate of early cancer is excellent in comparison with advanced cancer. Therefore, tremedous efforts would be made for the early detection of gastric cancer. We clinically reviewed our cases and the literatures of early gastric cancer (EGC). During the recent 7 years from Jan. 1981 to Aug. 1987, 82 cases of EGC were collected from Chungnam National University Hosptial, Daejeon St. Marie Hospital and Daejeon Eulji Hospital. The resuls were summerized as follows, 1) The incidence of EGC among gastric resection due to gastric cancer was 14.2% (51 cases among the 358 cases). 2) The overall male to female sex ratio was 1.6: 1, and the peak age incidence was 6th decade. 3) Symptoms and signs, in order of frquency, were as follows; epigastric pain (58.5%), epigastric discomfort (26.8%), indigestion (25.6%). 4) The most frequent macrotype of EGC was IIc (28%), and its combined type (46.3%). 5) The major locations of EGC were pylorus & antrum (52.4%) and angle (30.5%). 6) 28 cases among 82 EGC were confined to mucosa (34.1%), and metastasis to regional lymph node was found in 5 cases (6.1%). 7) The size of EGC was variable, but average 2.0 cm in diameter. 8) The most common microscopic tissue type of EGC was adenocarcinoma, poorly differentiated (63.4%). 9) Preoperative endoscopic gross finding was as follows; advanced cancer (48.6%), EGC (32.9%), benign lesion (18.6%). 10) 29 cases among 30 cases of follw-up were lived recently.
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