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      • KCI등재

        2003년 국내 원종계 및 종계의 추백리-가금티푸스 감염실태

        김애란,김재홍,이영주,조영미,권준헌,권용국,이윤정,최준구,조성준,김민철,이은경,김창섭,양흥구,곽상익,성환우,모인필,Kim, Ae Ran,Kim, Jae Hong,Lee, Young Ju,Cho, Young Mi,Kwon, Jun Hun,Kwon, Yong Kuk,Lee, Youn Jeong,Choi, Jun Gu,Joh, Sung Jun,Kim, Min C 대한수의학회 2006 大韓獸醫學會誌 Vol.46 No.4

        Serum samples of 30 chickens per flock from 6 grand parent stock (GPS) farms and 70 parent stock (PS) farms were collected for seroprevalent study of pullorum disease-fowl typhoid (PD-FT) infection by serum plate agglutination test (SPA). The incidence of PD-FT infection in GPS flocks and PS flocks were 0% and 15.7%, respectively. Especially PS flocks infected with PD-FT showed age dependent patterns that 22.2% of flocks between 20 to 30 weeks of age and 38.9% of flocks between 30 to 40 weeks of age were positive. The incidence of GPS flocks and PS flocks using Salmonella (S.) gallinarum 9R (SG9R) live vaccine were 33.3% and 58.6%, respectively. The sero-positive rate of 11 flocks were 6.7-83.3% by SPA and 2.9-55.6% by enzyme linked immunosorbent assay (ELISA), and ELISA showed more lower antibody levels than SPA. Furthermore, specific antibodies produced by SG9R vaccination were detectable by SPA using SG9R antigen without cross-reaction with the PD-FT infection.

      • KCI등재

        이중으로 집중된 동적 미세 다엽콜리메이터의 선량학적 특성 평가

        김애란,서재혁,신헌주,박형욱,이기웅,이재춘,김신욱,김지나,박혜리,이희관,강영남,Kim, Ae Ran,Seo, Jae-Hyuk,Shin, Hun-Joo,Park, Hyeong Wook,Lee, Ki Woong,Lee, Jae Choon,Kim, Shin-Wook,Kim, Ji Na,Park, Hyeli,Lee, Heui-Kwan,Kang, Young-Nam Korean Society of Medical Physics 2015 의학물리 Vol.26 No.4

        이중으로 집중된 미세 다엽콜리메이터(Double-focused micro Multileaf Collimator: ${\mu}MLC$)는 보통의 다엽콜리메이터(Multileaf Collimator: MLC)에 비하여 조사면 가장자리 부분의 선량을 급격하게 줄여준다. 이러한 특성 때문에, 미세 다엽 콜리메이터는 정위적 방사선 수술과 치료(Stereotactic Radio-Surgery/RadioTtherapy, SRS/SRT)에 사용되어 왔다. 우리는 Elekta Synergy 선형가속기에 이중으로 집중된 동적 미세 다엽콜리메이터(Double-focused Dynamic micro-Multileaf Collimator: DMLC)를 부착하여 선량학적 특성을 평가하였다. 본 연구에서는, 필름(GafChromic EBT2 film), EDGE 다이오드 검출기, 3차원 물 팬텀을 이용하였다. 깊이선량백분율(Percent Depth Dose, PDD), 엽 투과도(leaf leakage), 반그림자(Penumbra)를 측정하였고, 모든 데이터들은 6MV 광자선으로 측정하였다. 그 결과, DMLC가 1% 이내의 투과도를 갖는것을 확인할 수 있었다. DMLC는 이중으로 집중 되는 구조를 가졌기 때문에 반 그림자가 조사야 크기에 대하여 독립적인 것을 확인하였다. 본 연구에서는 DMLC의 선량학적 특성을 바탕으로, Elekta Synergy에 부착된 DMLC의 적용 가능성을 증명하였다. Double-focused micro-Multileaf Collimator (${\mu}MLC$) is able to create radiation fields having sharper dose gradients at the field edges than common MLC. Therefore, ${\mu}MLC$ has been used for the stereotactic radiosurgery (SRS) and Stereotactic Radiotherapy (SRT). We evaluated the dosimetric characteristics of a doublefocused Dynamic-${\mu}MLC$ (DMLC) attached to the Elekta Synergy linear accelerator. For this study, the dosimetric parameters including, Percent Depth Dose (PDD), Leaf leakage and penumbra, have been measured by using of the radiochromic films (GafChromic EBT2), EDGE diode detector and three-dimensional water phantom. All datas were measured on 6 MV x-ray. As a result, The DMLC shows transmission below to 1% and because of double-focused construction of the DMLC, the penumbras of fields with DMLC are independent from the field sizes. In this paper, the resulting dosimetric evaluations proved the applicability of the DMLC attached to the Elekta Synergy linear accelerator.

      • 백양사 사찰림 비자나무 임분의 테르펜류 잔존량과 성분특성

        김애란 ( Ae-ran Kim ),양천은 ( Cheon-eun Yang ),허예나 ( Ye-na Heo ),김강산 ( Kang-san Kim ),박종석 ( Jong-suk Park ),김은일 ( Eun-il Km ),안기완 ( Ki-wan An ),김민희 ( Min-hee Kim ) 한국산림경제학회 2018 산림경제연구 Vol.25 No.1

        본 연구는 비자나무 임분내의 NVOCs 잔존량을 규명하고 비자나무에서 방출되는 NVOCs의 성분을 규명하고자 수행하였다. 실험은 2017년 4월부터 10월까지, 총 7회에 걸쳐 장성군에 위치한 내장산국립공원 백양지구 내 비자나무 임분에서 이루어졌다. NVOCs의 포집은 가지에 테틀러백을 씌우고 순수공기를 주입시켜 11시부터 12시까지 포집하는 테틀러백 법과 임분 내에서 직접 포집하는 미니펌프법으로 실시하였다. 테틀러백을 이용한 비자나무의 월별 NVOCs 잔존량은 각각 146,156 pptv/4월, 176,786 pptv/5월, 132,466 pptv/6월, 22,908pptv/7월, 73,782pptv/8월, 38,736pptv/9월, 41,233pptv/10월로 측정되었으며, 비자나무 임분 내에서 측정한 월별 NVOCs는 5,169 pptv/4월, 11,940 pptv/5월, 7,657 pptv/6월, 6,864pptv/7월, 13,912pptv/8월, 2,640pptv/9월, 1,828pptv/10월로 나타났다. NVOCs의 15종에 대한 성분을 7회 평균값을 산출한 결과, limonene이 약 43∼52%로 가장 많은 함량을 차지하고 있었으며 α-pinene 은 약 35∼39%의 비율인 것으로 분석되었다. 비자나무를 대상으로 포집방법의 차이에 따른 NVOCs 잔존량은 최소 15배에서 28배까지 차이를 보였으며, NVOCs 성분의 대부분이 limonene과 α-pinene으로 나타났다. 임분내 NVOCs에 대한 기초자료로서 활용될 수 있을 것으로 사료된다. This study aims to identify the NVOCs(Natural Volatile Organic Compound) retention volume of Torreya nucifera stand and the characteristic of chemical compositions of the NVOCs emitted from it. This experiment was performed seven times in total from April to October, 2017 at Torreya nucifera temple forest of Naejangsan National Park Baekyangsa in Jangseong-gun. Two methods were used as the sampling methods of NVOCs. The first one was to use tedlar bags. After placing a tedlarbag over a branch and leafs, we injected pure air into it and captured NVOCs for 2 hours from 11 a.m. to 12 p.m. The second one was to capture NVOCs directly in a stand of Torreya nucifera used mini pump. When tedlarbags were used, the monthly NVOCs retention volumes of Torreya nucifera were 146,156pptv/April, 176,786pptv/May and 132,466pptv/June, 22,908pptv/July, 73,782pptv /August, 38,736pptv/September, 41,233pptv/October respectively. In addition, when measured using minipump in the stand, the monthly NVOCs retention volumes were 5,169 pptv/April, 11,940pptv /May, and 7,657pptv/June, 6,864pptv/July, 13,912pptv/August, 2,640pptv/September, 1,828pptv/October respectively. In order to identify the characteristic of compositions, 15 kinds of terpenes were analyzed, and their average was calculated seven times. As a result, limonene had the highest percentage of 43 to 52%, and α-pinene accounted for 35 to 39%. The NVOCs retention volume depended on the sampling method from Torreya nucifera stand. The highest NVOCs retention volume was at least 15 to 28 times higher, and most components of NVOCs were limonene and α-pinene. It is believed that NVOCs within the domain can be utilized as a baseline.

      • KCI등재

        임상 한의사의 이침 사용 실태 조사 보고

        김애란 ( Ae Ran Kim ),이상훈 ( Sang Hun Lee ),김정은 ( Jung Eun Kim ),김보영 ( Bo Young Kim ),강경원 ( Kyung Won Kang ),최선미 ( Sun Mi Choi ) 경락경혈학회 2011 Korean Journal of Acupuncture Vol.28 No.4

        Objectives: The survey was conducted to find out ear acupuncture usage of clinical traditional Korean medicine doctor and lay a foundation for the standards for its clinical application. Methods: An e-mail was sent to Korean medicine doctors whose email addresses are registered at the Association of Korea Oriental Medicine twice over two weeks. 280 completed questionnaires were used for the analysis. Results: 66.07% of respondents answered in use, whereas the answer that "less than 10 per 100 patient applied" was more than majority of 54.29%. The major field of treatment is addictive disorders such as smoking and the 80.11% patients got less than 3 days of treatment. Ear region was the most commonly treated area with 66.67%. Since the self removal frequency was high as 65.05% in compared to the case of visiting clinic. The rate of side effects was less than 10% (96.70%), and these side effects showed light symptoms such as "pain" (46.95%), itchiness (29.27%), flare (19.51%). The Acquired complements for improving ear acupuncture treatment was "the development of effective treatment manual" (28.57%) and "increasing insurance costs" (27.86%). Conclusions: Based on the survey, the vast majority of the TKM doctor used ear acupuncture but the frequency of use was low. We hope this study can be the basis for development of treatment manuals for various indications and safe treatment guidelines.

      • KCI등재

        산림체험 프로그램이 갱년기 여성에 미치는 생리·심리적 변화

        김애란 ( Ae-ran Kim ),안기완 ( Ki-wan An ) 한국산림경제학회 2021 산림경제연구 Vol.28 No.1

        본 연구는 산림체험이 갱년기 중년여성의 갱년기 증상 및 삶의 질의 변화를 규명하고자 비자나무 임분에서 치유 프로그램을 실시하였다. 피험자는 자발적 참여에 동의한 일반인 15명을 선정하였고, 전남대학교 생명윤리심사위원회의 심의를 받았다. 2019년 5월부터 10월까지, 총 6회의 산림체험 프로그램에 모두 참여한 7명의 피험자를 대상으로 수행하였고, 스트레스 감소를 규명하기 위해 생리적 척도는 심박수와 교감신경·부교감신경 활성수치를 측정하였다. 심리적 척도는 폐경증상지수와 삶의 질 척도를 조사하였으며 비모수적 통계를 적용하였다. 그 결과, 첫째 심박변이도(z=-2.38, p<.05), 자율신경활성도(z=-2.20, p<.05), 심박변이전체활성도(z=-2.20, p<.05), 부교감신경활성도(z=-2.21, p<.05), 교감신경활성도 (z=-2.20, p<.05), 교감신경균형도(z=-2.20, p<.05)에서 산림체험 사전·사후의 값은 유의함을 보였다. 둘째 갱년기 증상(z=-2.23, p<.05) 및 폐경증상지수의 신체적 증상(z=-2.03, p<.05), 정신적 증상(z=-2.07, p<.05)에 있어서 산림체험 전과 후의 값은 유의한 변화를 보였다. 즉, 산림체험 프로그램이 갱년기 증상을 다소 완화시킨 유의미한 결과를 얻었다. 셋째 산림체험 후의 삶의 질(z=-2.39, p<.05)지수 값은 체험 전에 비해 향상되는 결과를 얻었다. 그러나 본 연구의 한계점은 피험자의 수가 적었다는 점으로 보다 많은 연구자료 수집이 필요하다. Middle-aged women are stressed by postmenopausal symptoms, and the higher the stress, the higher the symptoms of menopause and the lower the quality of life. This study conducted a forest experience programs in the forest stand of Torreya nucifera(L.) to identify changes in menopause symptoms and quality of life in middle-aged women in menopause. The subjects selected 15 ordinary people who agreed to voluntarily participate, and reviewed the bioethics review committee of Chonnam National University. From May to October 2019, It was conducted on seven subjects who participated in a total of six forest experience programs and physiological measures measured heart rate, sympathetic nerve and parasympathetic nerve activity levels to determine stress reduction. Psychological measures examined the Menopause Symptom Index and WHOQOL-BREF which applied nonparametric statistics. As a result, First, the post-experience values were significant than before the forest experience programs in the heart rate variability(z=-2.38, p<.05), total power(z=-2.20, p<.05), high Frequency(z=-2.21, p<.05), Low Frequency(z=-2.20, p<.05), Normalized LF(z=-2.20, p<.05). Second, pre-forest experience and post-experience values showed significant changes in the physical(z=-2.03, p<.05) and mental(z=-2.07, p<.05) symptoms of menopause and menopause symptoms index. Third, the quality of life index(z=-2.39, p<.05) was improved before and after the forest experience. In other words, forest experience programs have achieved significant results that have somewhat alleviated menopause symptoms. However, the limitation of this study is that the number of subjects was small, which is why more research data are needed.

      • SCOPUSKCI등재

        Docetaxel과 Cisplatin으로 치료한 비소세포폐암환자에서 발생한 BOOP

        김애란 ( Ae Ran Kim ),김태영 ( Tae Young Kim ),이영민 ( Young Min Lee ),이승헌 ( Seung Heon Lee ),정수진 ( Soo Jin Jung ),이현경 ( Hyun Kyung Lee ) 대한결핵 및 호흡기학회 2010 Tuberculosis and Respiratory Diseases Vol.69 No.4

        A 60-year-old man was diagnosed with stage IV squamous cell carcinoma of lung and treated with weekly doses of docetaxel and cisplatin. Tumor mass and mediastinal lymphadenopathy disappeared after 4.5 cycles of chemotherapy. At one week post final chemotherapy, the patients developed sudden shortness of breath. New, multifocal infiltrations developed on both lungs without definitive evidence of infection. Despite administration of broad spectrum antibiotics, the lung lesion did not improve, so bronchoalveolar lavage and computed tomography-guided lung biopsy were performed. The proportion of lymphocytes was increased markedly and histopathology revealed squamous cell carcinoma combined with bronchiolitis obliterans organizing pneumonia. After high dose corticosteroid therapy, dyspnea and the newly developed consolidation had decreased slightly. However, dyspnea and hypoxemia increased again because of aggravated lung cancer since chemotherapy had stopped. Chemotherapy couldn`t be restarted due to the poor performance status of the patient. Later, patient died of respiratory failure from poor general condition and progression of lung cancer.

      • KCI등재

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