Phentermine 및 Phendimetrazine으로 유발된 정신병적 장애 및 양극성 장애 증례군 연구

김수영,김태석,김대진,채정호,이창욱,주수현,Kim, Soo Young,Kim, Tae-Suk,Kim, Dai-Jin,Chae, Jeong-Ho,Lee, Chang Uk,Joo, Soo Hyun 대한생물정신의학회 2022 생물정신의학 Vol.29 No.1

Objectives Recently, weight loss has emerged as a national concern in South Korea, and this has resulted in an increase in the frequency of use of central nervous system (CNS)-stimulating appetite suppressants. This study aimed to collect cases of psychotic disorders and bipolar disorders triggered by phentermine and phendimetrazine and explore the clinical features and courses. Methods In this retrospective study, we analyzed the electronic medical records of patients and selected eight patients who developed psychotic symptoms and manic symptoms for the first time after taking phentermine and phendimetrazine. All cases were reviewed, and their clinical features and course were summarized. Results All eight patients developed psychotic symptoms, and one had accompanying manic symptoms. The final diagnosis was appetite-suppressant-induced psychotic disorder in four patients, schizophrenia in three, and appetite-suppressant-induced bipolar disorder in one. In addition, three patients were diagnosed as having substance-use disorder. The key psychotic symptoms of these patients were hallucinations and paranoia. Conclusions These case findings suggest that phentermine and phendimetrazine can cause psychotic disorder, bipolar disorder, or substance use disorder and that medical professionals and the public should practice caution when prescribing and using these drugs.

드라이클리닝 근로자들의 유기용제 폭로와 자각증상

김수영,김정윤,이연경,이석구,이영수,조영채,이태용,이동배,Kim, Soo-Young,Kim, Jeong-Yun,Lee, Yeon-Kyeng,Lee, Sok-Goo,Lee, Young-Soo,Cho, Young-Chae,Lee, Tae-Young,Lee, Dong-Bae 대한예방의학회 1998 예방의학회지 Vol.31 No.4

To investigate the exposure levels of organic solvents and subjective symptoms of dry-cleaning workers, 77 male and 52 female dry-cleaning workers who had been worked in a small city of Chungnam province, and a large city, Taejon were selected for the study group. Air concentrations of organic solvents in the working environment were analyzed, and subjective symptoms of dry-cleaning workers were surveyed, from July to August 1996. The results obtained were as follows : 1. The concentrations of organic solvents in the working environment were within permissible TLV-TWA limits. 2. For the 13 symptom clusters, the most frequently complained symptom clusters were fatigue as 71.3%, and followed by depression and urinary disturbances as 53.5% and 51.9%. Other symptom clusters complained were below 50%. 3. Positive response rates of subjective symptoms were significantly higher in worker groups such as lived in a large city, female, higher education level, more frequently alcohol drinking, higher concentration of organic solvent in working environment, work in alone. 4. Workers who had used solvent B showed 2.3 point higher scores of subjective symptoms than those of solvent A. Of the subjective symptoms scores, amnesia and nervousness were higher in solvent B user group than solvent B user group. 5. As a result of factor analysis, 3 factors such as depression, urinary disturbance and neurologic disturbance were selected. 6. As a result of the logistic regression analysis, sex, the number of fellow workers, working time, region, job tenure, smoking, alcohol drinking, ventilating system, concentration of organic solvent in working environment and place of residence were selected for the related variables. For the conclusion, even though the concentrations of organic solvents in the working environments of dry-cleaning workers were within permissible limit of TLV-TWA, many dry-cleaning workers complained symptoms, such as fatigue, depression, urinary disturbances and so on. And the factors affecting to the symptoms of dry-cleaning workers were the number of fellow workers, work hours, region, job tenure, smoking and alcohol drinking.

조원경본 「김영철전(金英哲傳)」의 로컬리티 : 박재연본과의 비교로 본

김수영 ( Kim Soo-young ) 민족문학사학회·민족문학사연구소 2021 민족문학사연구 Vol.76 No.-

조원경본은 1762년 무렵에 필사된 「김영철전(金英哲傳)」의 한문본 이본이다. 조원경본은 긴 편폭의 연의소설 계열 현전 이본 중 ‘김영철 서사’의 효시인 김응원(金應元)의 「김영철유사(金英哲遺事)」에 시간적으로 가장 가깝다. 본고에서는 이처럼 선본(先本)에 해당되는 조원경본의 로컬리티를 후대의 다른 한문본 이본인 박재연본과의 비교를 통해 고찰했다. 조원경본과 박재연본은 모두 연의소설 계열의 이본으로서 서사의 경개가 대체로 유사하다. 이에 평안도 지역의 특수성과 그 하위주체의 비판적 문제제기가 공통적으로 보인다. 그렇기는 하지만 조원경본의 로컬리티가 박재연본보다 한층 더 뚜렷하고 예리하다. 첫째, 조원경본은 17세기 평안도 하층민 김영철이 겪은 고통이 국가의 공적 체제에서 기인하는 것임을 일관되게 비판적으로 말하고 있다. 이와 달리 후대의 박재연본은 김영철이 겪은 고통이 유림이라는 한 위정자의 사적 원한에서 기인하는 것으로 일부분을 개작해 놓았다. 둘째, 조원경본의 끝부분에는 하위주체로서 각성한 김영철 자신이 한양의 조정을 향해 스스로 목소리를 내어 자신의 고통을 말하고, 공적을 인정받게 해달라고 호소한 사건이 명확히 서술되어 있다. 이와 달리 박재연본은 이 부분이 다소 모호하게 서술되어 있다. 이처럼 박재연본에 비해 조원경본에 로컬리티가 현저하게 보이는 것은, 「김영철유사」에 담긴 로컬리티와 관련된 문제의식이 크게 퇴색되지 않은 채 조원경본으로 전승된 결과로 추정된다. Jowongyeongbon(Kimyoungcheoljeon owned by Jo Won-gyeong) is the text of the classical Chinese version of Kimyoungcheoljeon, which was copied around 1762. A relatively long version of the scripts that exist today, Jowongyeongbon is the closest in time to Kimyoungcheolyusa, the origin of Kim Young-cheol’s narrative. In this paper, the locality of Jowongyeong_ bon, which was written in this early period, was examined by comparing it with the other later classical Chinese version of Parkjaeyeonbon (Kimyoungcheoljeon owned by Park Jae-yeon). Both Jowongyeongbon and Parkjaeyeonbon are scripts of the Yeon-eui(演義) novel series, and the narratives in these two works are generally similar. The local specificity of Pyeongando and the critical problem raised by its subaltern have much in common. However, the locality of Jowongyeongbon is more distinct and sharper than that of Parkjaeyeonbon. The reason behind this difference is that Jowongyeongbon was passed without much fading of the awareness of the locality contained in Kim Eung-won’s Kimyoungcheolyusa.

비주 버팀목으로 흡수성 고정판을 이용한 비첨 성형술

김수영,이수향,황은아,최현곤,김순흠,신동혁,엄기일,Kim, Soo-Young,Lee, Soo-Hyang,Hwang, Eun-A,Choi, Hyun-Gon,Kim, Soon-Heum,Shin, Dong-Hyeok,Uhm, Ki-Il 대한성형외과학회 2010 Archives of Plastic Surgery Vol.37 No.3

Purpose: Most surgeons have used autogenous cartilage for columella strut graft. But the supply of autogenous cartilage is often limited. So, this study is to investigate the usefulness of biodegradable plate as columella strut material. Methods: We studied 19 patients who have secondary cleft nasal deformity. Patients were divided into two groups. Group A patients who were not closed their growth plate underwent columella strut graft only with biodegradable plate through endonasal approach. The biodegradable plate was inserted between nasal tip and anterior nasal spine. Group B patients were closed their growth plate. They had an operation for columella strut graft with biodegradable plate fixed with autogenous conchal cartilage. If nasal tip projection was insufficient, we performed additionally onlay graft on nasal tip with autogenous soft tissue or remnant cartilage. Results: As a result of mean 14 months follow-up, we achieved a good nasal tip projection, narrowing of interalar distance and symmetrical nostril shape. No specific complications were reported except 2 cases, which were the extrusion of biodegradable plate into the nasal cavity and Staphylococcus aureus infection. Conclusion: The columella strut graft using biodegradable plate is simple and effective method. Biodegradable plate can be a good substitute for columella strut in patients who can not use autogenous cartilages.

Korean guidelines for postpolypectomy colonoscopic surveillance: 2022 revised edition

김수영,곽민섭,Soon Man Yoon,정윤호,Jong Wook Kim,Sun-Jin Boo,Eun Hye Oh,Seong Ran Jeon,Seung-Joo Nam,Seon-Young Park,Soo-Kyung Park,전성란,Dong Hoon Baek,Mi-Young Choi,Suyeon Park,Jeong-Sik Byeon,Hyung Kil Kim,Jo 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.6

Colonoscopic polypectomy is effective in decreasing the incidence and mortality of colorectal cancer (CRC). Premalignant polyps discoveredduring colonoscopy are associated with the risk of metachronous advanced neoplasia. Postpolypectomy surveillance is the most important meth-od for the management of advanced metachronous neoplasia. A more efficient and evidence-based guideline for postpolypectomy surveillance isrequired because of limited medical resources and concerns regarding colonoscopy complications. In these consensus guidelines, an analytic ap-proach was used to address all reliable evidence to interpret the predictors of CRC or advanced neoplasia during surveillance colonoscopy. Thekey recommendations state that the high-risk findings for metachronous CRC following polypectomy are as follows: (1) adenoma ≥10 mm in size;(2) 3 to 5 (or more) adenomas; (3) tubulovillous or villous adenoma; (4) adenoma containing high-grade dysplasia; (5) traditional serrated adeno-ma; (6) sessile serrated lesion (SSL) containing any grade of dysplasia; (7) serrated polyp of at least 10 mm in size; and (8) 3 to 5 (or more) SSLs. More studies are needed to fully comprehend the patients most likely to benefit from surveillance colonoscopy and the ideal surveillance intervalto prevent metachronous CRC.

수출회화로서 기산 김준근(箕山 金俊根) 풍속화 연구

김수영,Kim, Soo-Young 한국미술이론학회 2009 미술이론과 현장 Vol.8 No.-

Kim, Jun-Geun(Gisan) was a late 19th century Chosen dynasty painter who created numerous genre paintings for West European clients in the newly opened treaty ports of Wonsan, Busan and Inchon. The treaty ports in the late 19th century Chosen represented of the crossroads the economy, values, and the institutions of the West European powers. In particular, the agriculture-based economy, Confucianism, and land-owner noble class started being eroded by a commerce-based economy, the values of Christianity, West European institution, and a new class of people who amassed wealth from commerce. As Kim, Jun-Geun's paintings were created for sale to West European clients, they exhibit characteristics that are distinct from the traditional genre paintings in terms of presentation style and the selection of the subject matters. The export genre painting originated in the 18th century around Guangdong, China. Broadly, there are two styles of genre paintings: the Guangzhou style and Ningbo style. Kim, Jun-Geun's paintings resemble the Ningbo style. The Ningbo style tends to highlight the main subjects, form an album of small paintings, and provide a simple treatment of the scenes without the background. Kim, Jun-Geun's paintings cover most aspects of life of common people of his time, ranging well beyond the subjects matters of the traditional genre paintings. His subject matters include the scenes of funeral, folk games, Buddhist and ancestor worship, prison and punishment, shaman custom, debauchees, government officials' formal trips, beggars and handicapped, etc. Many of the subjects are the neglected and the oppressed of the society. And he presents in detail the dress and its ornament that the subjects wear, and all the utensils and things around them. Besides, his subjects' faces are generally expressionless, and their postures are stiff; as such, the feeling of liveliness or movement is lacking. It may be the results of Kim, Jun-Geun's taking the other perspective, namely of his West European clients, rather than his own. The adoption of the other perspective may in turn be a product of the Social Darwinism and the new sense of values that accompanied the infusion of Christianity and West European institutions. Kim, Jun-Geun's portrayals of his subjects appear to reflect the attributes with which the West European Orientalists' of the period characterized the people of the Far East, namely, backwardness, barbarity, irrationality, violence, and mysticism.

유아의 창의성과 음악능력이 음악적 창의성에 미치는 영향

정나영(Jung Na Young),김수영(Kim Soo-Young) 한국육아지원학회 2010 육아지원연구 Vol.5 No.2

본 연구는 유아의 연령과 성별에 따른 창의성, 음악능력, 그리고 음악적 창의성의 차이를 살펴보고, 유아의 창의성과 음악능력이 유아의 음악적 창의성에 미치는 영향을 알아보는 것을 목적으로 하였다. 이를 위해 대구․경북에 위치한 유치원과 어린이집에 다니고 있는 만 4, 5세 유아 338명의 창의성, 음 악능력, 그리고 음악적 창의성을 측정하였으며, 자료 분석을 위해 MANOVA와 중다회귀분석을 실시하 였다. 연구 결과 첫째, 유아의 음악 능력은 연령에 따른 차이가 유의하게 나타났으나, 유아의 창의성과 음악적 창의성은 연령과 성별에 따른 차이가 유의하지 않게 나타났다. 둘째, 유아의 창의성은 유아의 음악적 창의성에 유의한 영향을 미치는 것으로 나타났으나, 유아의 음악능력은 유아의 음악적 창의성 에 유의한 영향을 미치지 않는 것으로 나타났다. The purpose of this study was to analyze the effects of children’s creativity and musical ability on children’s musical creativity. 338 children, aging 4~5 who enrolled at kindergarten and child care center in Daegu and Gyeongbuk province were selected for the research and analysis. Three different methods were used as a tool for the research. First, children’s creativity evaluation scales for the teacher developed by Rho Young-hee, Kim Kyung-chul and Kim Ho(2006) was used to measure the children’s creativity. Second, PMMA(Primary Measure of Music Audition) developed by Gordon(1986) which was translated to Korean by Shin In-suk(1994) was used to measure the children’s musical ability. Finally, MCSM(Measures of Creativity in Sound and Music) developed by Wang(1985) which was translated to Korean by Hue Sun-hee(1996) was used to measure children’s musical creativity. All collected datum were analyzed by MANOVA Process of SPSS /PC and Multiple Regression Analysis. Summaries of the research results are as follows. First, children’s creativity had no differences in age and gender excepting partial differences in children’s independence and against-norm. Second, children’s musical ability had significant differences in age but no differences in gender. Third, children’s musical creativity had no differences in age and gender. Fourth, children’s creativity effected significantly on the children’s musical fluency and musical imagination, but not on children’s musical originality. Finally, children’s musical ability didn’t effect on the children’s musical creativity.

흰쥐 폐에서 Prednisone 에 의한 산소 독성과 Liposomal Superoxide Dismutase 의 보호 효과

김수영,백광진,이희성 ( Soo Young Kim,Kwang Jin Baek,Hee Sung Lee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.3

The changes of superoxide dismutase (SOD), catalase, peroxidase and xanthine oxidase activities in the lung were observed after treating rats either with prednisone (10 ㎎/100 g body weight, group A) alone or with oral liposomal superoxide dismutase (3,000 units) followed by prednisone (10 ㎎/100 g body weight, group B). The results were summarized as follows: 1. In group A, Cu, Zn-SOD activity was higher than non-treated control values, but group B showed lower than that in the control. 2. The activity of Mn-SOD in group A increased progressively until the 3rd day after prednisone treatment and then decreased thereafter, but in group B, the activity was not changed except on the 4th day after the treatment. 3. In all experimental groups, the catalase activity was higher than that in the control, and gorup B showed higher activity than that in group A except on the 4th day after the treatment. 4. The activity of peroxidase in group A was higher than that in the control, but the activity in group B was similar to that in control. 5. In group A, xanthine oxidase activity showed higher than that in the control and group B except on the 1st day after the treatment, and the activity in group A increased with time. The above results suggest that prednisone administration could enhance the xanthine oxidase activity which lead to the production of oxygen radicals in the lung, and that the liposomal SOD may effectively protect the lung from the oxygen toxicity.

근거중심의학과 체계적 고찰

김수영,Kim, Soo Young 한국의료질향상학회 2006 한국의료질향상학회지 Vol.12 No.2

체계적 고찰은 명확히 정의된 문헌검색에 기반하고, 결정된 기준(criteria)을 이용하여 선택된 문헌의 질을 평가하며, 타당성이 입증된 방법으로 분석을 시행하는 리뷰의 한 형태이다. 체계적 고찰은 (1)답을 얻고자 하는 질문을 공식화 하고 이에 대한 프로토콜을 작성하고, (2)해당 질문에 대한 일차 연구를 찾아서 포함시키고 (3)자료의 질을 평가하고, (4)자료를 추출하여 뽑고, (5)자료를 분석하며, (6)결과를 해석하고 보고서를 작성하는 순서로 이루어진다 하지만 체계적 고찰 혹은 메타분석이 모든 문제에 대한 해결책은 아니다. 메타분석이 수행되었다고 하더라도 질이 나쁜 연구가 포함되거나 질 문제를 무시한 경우, 이질성에 대해 적절한 주의를 기울이지 못할 때, 무차별적인 자료 병합으로 결론이 정확하지 않은 경우, 출판 비뚤림, 시간 지체 비뚤림, 이중 출판 비뚤림, 언어 비뚤림, 결과 보고 비뚤림과 같은 보고 비뚤림이 문제가 되는 경우에는 메타분석 혹은 체계적 고찰이 잘못된 결론으로 도달하도록 할 수 있다. 따라서 올바른 방법론에 기초한 체계적 고찰만이 현존하는 모든 근거를 결합하여 올바른 결론으로 이끌 수 있다.

양방향 삼중편심 버터플라이 밸브 개발

김수영,이동명,배정훈,신성철,설창호,Kim, Soo-Young,Lee, Dong-Myung,Bae, Jung-Hoon,Shin, Sung-Chul,Sul, Chang-Ho 대한조선학회 2009 大韓造船學會 論文集 Vol.46 No.5

In naval architecture and offshore engineering, the development and a broad use has been achieved in the field of flow control valves for pipe system. Butterfly valves are also widely used for flow control, but there are not many studies for triple-eccentric butterfly valves. Moreover, if the fluid of pipeline flows in the bi-direction then it makes more complicate to adapt triple-eccentric butterfly valves to flow control. In this study, we are trying to develop a bi-directional triple-eccentric butterfly valve through sealing mechanism and stem design study. Digital mockup using 3D CAD was constructed for shape interference check and structural analysis was conducted for structural safety. Also we performed leakage test to check out the durability of the bi-directional pressure for the developed valve.